• Proceedings of the PSK Conference
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• 2005.11a
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• pp.182-183
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• 2005

• Proceedings of the Korean Society of Sericultural Science Conference
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• 2003.10a
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• pp.87-90
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• 2003

Cytokines represent an essential part of the innate immune response in mammals. Recently, several studies have reported presence of cytokine-like activities and molecules in the invertebrates such as echinoderms, tunicates, molluscs and insects (Beck and Habicht, 1986; Beck et al.; 1959; Ottaviani et al.; 1993; Franchini, 1996). The cytokines found in those organisms include IL-1, IL-2, IL-6, and tumor necrosis factor (TNF). (omitted)

• Proceedings of the Korean Society of Crop Science Conference
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• 2005.04a
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• pp.178-179
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• 2005

• Food Science of Animal Resources
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• v.43 no.1
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• pp.101-112
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• 2023

This study aimed to assess whether genomic DNA (gDNA) extracted from Pediococcus acidilactici inhibits Porphyromonas gingivalis lipopolysaccharide (LPS)-induced inflammatory responses in RAW 264.7 cells. Pretreatment with gDNA of P. acidilactici K10 or P. acidilactici HW01 for 15 h effectively inhibited P. gingivalis LPS-induced mRNA expression of interleukin (IL)-1β, IL-6, and monocyte chemoattractant protein (MCP)-1. Although both gDNAs did not dose-dependently inhibit P. gingivalis LPS-induced mRNA expression of IL-6 and MCP-1, they inhibited IL-1β mRNA expression in a dose-dependent manner. Moreover, pretreatment with both gDNAs inhibited the secretion of IL-1β, IL-6, and MCP-1. When RAW 264.7 cells were stimulated with P. gingivalis LPS alone, the phosphorylation of mitogen-activated protein kinases (MAPKs) was increased. However, the phosphorylation of MAPKs was reduced in the presence of gDNAs. Furthermore, both gDNAs restored IκBα degradation induced by P. gingivalis LPS, indicating that both gDNAs suppressed the activation of nuclear factor-κB (NF-κB). In summary, P. acidilactici gDNA could inhibit P. gingivalis LPS-induced inflammatory responses through the suppression of MAPKs and NF-κB, suggesting that P. acidilactici gDNA could be effective in preventing periodontitis.

• Journal of architectural history
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• v.13 no.3
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• pp.21-36
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• 2004

Most of the studies on Confucian Architecture dealt with the administrative system and typification. The study was about the outline buildings of the Architecture. However, specific view of personal architecture is limited. The aim of this study is to clarify the idea of Seonbi, Confucian Scholars in Choson Dynasty, in building the second house, Byul-Seo Architecture. The Byul-Seo was used to Jang-Su(藏修) for training oneself and teaching his students, and You-Sik(遊息) for strolling the surrounding of nature. The Byel-Seo in Bogil-do by Gosan Yoon, Sun-Do is influenced not only by the idea of Confucianism which is 'knowing through by approaching to object(格物致知)', but also by Feng-shui and Taoism. From the idea of Gosan Yoon, Sun-Do in Byul-Seo Architecture, ecology and spirit of the times must applied to our modern architecture.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.44 no.10
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• pp.148-155
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• 2007

The routing optimization mode, which Mobile IPv6 provides for the direct communication between a mobile node and its correspond node, introduces various security threats, thus causing several protocols to be proposed for the secure binding update procedure. In particular, the Kang-Park protocol, which Kang and Park presented in 2005, achieves the optimized cryptographic operations and the strong security, while based on its unique security proxy structure. In spite of such advantages, it has some drawbacks in terms of security and efficiency. This paper improves the Kang-Park protocol through the strong CoA validation and early binding update methods. Also, we show that the improved protocol is better than others.

• IMMUNE NETWORK
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• v.12 no.5
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• pp.213-216
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• 2012

Our previous report showed that polyacetylene compound, 1-Heptadecene-11, 13-diyne-8, 9, 10-triol (PA) from the root of Cirsium japonicum var. ussuriense has anti-inflammatory activity. In this study we investigated the role of the PA as inhibitor of caspase-1, which converts prointerleukin-$1{\beta}$ (proIL-$1{\beta}$) to active IL-$1{\beta}$ and is activated by inflammasome involved in the inflammatory process. We tested the effect of PA on the production of pro-inflammatory cytokines, IL-$1{\beta}$ in murine macrophage cell line, RAW264.7. PA inhibited lipopolysaccharide (LPS)-induced IL-$1{\beta}$ production by macrophages at a dose dependent manner. PA also suppressed the activation of caspase-1. The mRNA level of ASC (apoptosis-associated spec-like protein containing a CARD), an important adaptor protein of inflammasome, was decreased in the PA treated group. Therefore our results suggest that the anti-inflammatory effect of PA is due to inhibit the caspase-1 activation.

• Proceedings of the Korean Society of Crop Science Conference
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• 2005.04a
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• pp.174-175
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• 2005

• 대한예방의학회:학술대회논문집
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• 2005.10a
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• pp.322-322
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• 2005

• 대한예방의학회:학술대회논문집
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• 1999.10a
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• pp.27-28
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• 1999