• Title/Summary/Keyword: KPS

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Nanotechnology in Cancer Therapy: Overview and Applications

  • Choi, Eun-Joo
    • Journal of Pharmaceutical Investigation
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    • v.41 no.2
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    • pp.59-65
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    • 2011
  • Nanotechnology for cancer therapy is playing a pivotal role in dramatically improving current approaches to cancer detection, diagnosis, and therapy while reducing toxic side effects associated with previous cancer therapy. A widespread understanding of these new technologies will lead to develop the more refined design of optimized nanoparticles with improved selectivity, efficacy and safety in the clinical practice of oncology. This review provides an integrated overview of applications and advances of nanotechnology in cancer therapy, based on molecular diagnostics, treatment, monitoring, target drug delivery, approved nanoparticle-based chemotherapeutic agents, and current clinical trials in the development of nanomedicine and ultimately personalized medicine.

Crystal Forms of Ziprasidone (지프라시돈의 결정형)

  • Youn, Mi-Hee;Bang, Hyo-Chun;Sohn, Young-Taek
    • Journal of Pharmaceutical Investigation
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    • v.39 no.2
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    • pp.117-120
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    • 2009
  • Two crystal forms of ziprasidone have been isolated by recrystallization from different organic solvents and characterized by differential scanning calorimetry, powder X-ray diffractometry and thermogravimetric analysis. It was confirmed that Form 2 has the same crystal structure as Form 1.

국제 협력 - 제34회 한·일 원자력산업 세미나

  • 한국원자력산업회의
    • Nuclear industry
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    • v.37 no.10
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    • pp.68-71
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    • 2017
  • 한국원자력산업회의(KAIF)와 일본원자력산업협회(JAIF)가 공동으로 주최한 제34회 한 일 원자력산업세미나가 10월 16일(월)부터 10월 18일(수)까지 일본에서 개최되었다. 도쿄 Belle Salle 회의장에서 열린 이번 세미나에는 한국수력원자력, 한전KPS, 한전원자력연료, 한국원자력연구원 등 9개 기관에서 총 22명의 한국 측 대표단이 참석하여 논문 발표와 함께 후쿠시마 제1원전, 오나가와 원전을 방문하는 산업시찰 일정을 소화했다. 이번 세미나에서 행한 한국 측 대표단장(강재열 한국원자력산업회의 부회장)의 개회사와 폐회사를 게재한다.

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Synthesis and Biocompatibility of Graft Copolymer of Butyl Methacrylate onto Gelatin (Gelatin에 Butyl Methacrylate 그라프트 공중합체의 합성과 생체적합성)

  • 김상기;김공수
    • Journal of Biomedical Engineering Research
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    • v.11 no.1
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    • pp.47-56
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    • 1990
  • The grafting of butyl methacrylate onto gelatin was investigated by potassium persulfate(KPS) redox system in aqueous solution. The optimum conditions of grafting were observed, and the physical property and the biocolnpatibility of graft copolymer membrane were examined. The gas permeability and the biodegradation by bacteria were decreased with the grafting percentage increased, and tensile strength increased with the grafting percentage increased.

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Crystal Form of Cefuroxime axetil (세푸록심 악세틸의 결정형)

  • Kim, Bo-Yeon;Sohn, Young-Taek
    • Journal of Pharmaceutical Investigation
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    • v.37 no.1
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    • pp.23-26
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    • 2007
  • Two crystal forms of cefuroxime axetil were obtained by the recrystallization from different organic solvents and characterized by differential scanning calorimetry (DSC), X-ray powder diffraction (XRD). It was confirmed that two crystal forms are identical. The dissolution patterns of these two forms were also checked in 0.07 N HCl at $37{\pm}0.5^{\circ}C$, 100 rpm for 180 minutes. The transformation during storage was also studied.

정부의 규제 개혁과 원자력 안전 규제의 효과성

  • Choe, Gwang-Sik
    • Nuclear industry
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    • v.28 no.6
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    • pp.24-27
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    • 2008
  • "정부의 규제 개혁과 원자력 안전 규제의 효과성"을 주제로 한 2008년 제1회 원자력안전포럼이 6월 5일(목) 한국원자력안전기술원 본관 세미나실에서 개최되었다. 발표자들을 포함하여 과학기술부, 녹색연합, 월성원전 환경감시센터, 한수원(주), 원자력발전기술원, 한수원 원자력교육원, 한전KPS, 한전기술(주), 원자력안전기술원 등의 관계자 총 60여명이 참석한 본 포럼은 원자력안전기술원 안전정책실에서 기획 주관하였으며, 원자력안전기술원 장현섭 박사와 박윤원 박사가 진행을 담당하였고, 최광식 박사가 전체 발표 내용과 종합 토의 내용을 요약 정리하였다. 본 특집은 포럼 발표 내용을 발표자의 집필로 구성한 것이다.(편집자)

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국내외 측위정보서비스 동향 분석을 통한 중파서비스 정책방향 연구

  • 이유경;최금성;박우경;이형우
    • Proceedings of the Korean Institute of Navigation and Port Research Conference
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    • 2023.11a
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    • pp.172-174
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    • 2023
  • 최근 3년간 위성항법 보유 및 활용이 가능한 주요 국가들은 DGNSS 중파서비스를 중단하고 위성기반의 보정 서비스(SBAS) 제공 추세이다. 한국형 SBAS 서비스인 KASS가 개발 중에 따라 우리나라 해양분야 활용 가능성 검토 및 중파서비스에 대한 정책방향 연구가 필요하다.

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Prognostic Significance of CYFRA21-1, CEA and Hemoglobin in Patients with Esophageal Squamous Cancer Undergoing Concurrent Chemoradiotherapy

  • Zhang, Hai-Qin;Wang, Ren-Ben;Yan, Hong-Jiang;Zhao, Wei;Zhu, Kun-Li;Jiang, Shu-Mei;Hu, Xi-Gang;Yu, Jin-Ming
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.1
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    • pp.199-203
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    • 2012
  • Purpose: To evaluate the prognostic value of serum CYFRA21-1, CEA and hemoglobin levels regarding long-term survival of patients with esophageal squamous cell carcinoma (ESCC) treated with concurrent chemoradiotherapy (CRT). Methods: Age, gender, Karnofsky Performance Status (KPS), tumor location, tumor length, T stage, N stage and serum hemoglobin, and CYFRA21-1 and CEA levels before concurrent CRT were retrospectively investigated and related to outcome in 113 patients receiving 5-fluorouracil and cisplatin combined with radiotherapy for ESCC. The Kaplan-Meier method was used to analyze prognosis, the log-rank to compare groups, the Cox proportional hazards model for multivariate analysis, and ROC curve analysis for assessment of predictive performance of biologic markers. Results: The median survival time was 20.1 months and the 1-, 2-, 3-, 5- year overall survival rates were 66.4%, 43.4%, 31.9% and 15.0%, respectively. Univariate analysis showed that factors associated with prognosis were KPS, tumor length, T-stage, N-stage, hemoglobin, CYFRA21-1 and CEA level. Multivariate analysis showed T-stage, N-stage, hemoglobin, CYFRA21-1 and CEA level were independent predictors of prognosis. By ROC curve, CYFRA21-1 and hemoglobin showed better predictive performance for OS than CEA (AUC= 0.791, 0.704, 0.545; P=0.000, 0.000, 0.409). Conclusions: Of all clinicopathological and molecular factors, T stage, N stage, hemoglobin, CYFRA21-1 and CEA level were independent predictors of prognosis for patients with ESCC treated with concurrent CRT. Among biomarkers, CYFRA21-1 and hemoglobin may have a better predictive potential than CEA for long-term outcomes.