• YAKHAK HOEJI
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• v.57 no.6
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• pp.426-431
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• 2013

In our previous studies, 6-hydroxy-7-methoxychroman-2-carboxylic acid N-phenylamide (KL-1156) was identified as a good inhibitor of nuclear factor-${\kappa}B$ (NF-${\kappa}B$) activation. In continuation of our study, we describe the structure-activity relationship of chroman derivatives containing N-arylalkyl groups and their NF-${\kappa}B$ inhibitory activities. In addition, inhibitory effects of cell proliferation are evaluated against human cancer cell lines (NCI-H23 and PC-3). The most active compounds 3i and 3j contained diphenylethyl and diphenylpropyl side chain on amide nitrogen.

• Journal of Microbiology
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• v.44 no.2
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• pp.192-199
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• 2006

Pseudomonas putida KL47 is a natural isolate that assimilates benzene, 1-alkylbenzene $(C_1-C_4)$, biphenyl, p-cumate, and p-cymene. The genetic background of strain KL47 underlying the broad range of growth substrates was examined. It was found that the cym and cmt operons are constitutively expressed due to a lack of the cymR gene, and the tod operon is still inducible by toluene and biphenyl. The entire array of gene clusters responsible for the catabolism of toluene and p-cymene/p-cumate has been cloned in a cosmid vector, pLAFR3, and were named pEK6 and pEK27, respectively. The two inserts overlap one another and the nucleotide sequence (42,505 bp) comprising the cym, cmt, and tod operons and its flanking genes in KL47 are almost identical (>99 %) to those of P. putida F1. In the cloned DNA fragment, two genes with unknown functions, labeled cymZ and cmtR, were newly identified and show high sequence homology to dienelactone hydrolase and CymR proteins, respectively. The cmtR gene was identified in the place of the cmtI gene of previous annotation. Western blot analysis showed that, in strains F1 and KL47, the todT gene is not expressed during growth on Luria Bertani medium. In minimal basal salt medium, expression of the todT gene is inducible by toluene, but not by biphenyl in strain F1; however, it is constantly expressed in strain KL47, indicating that high levels of expression of the todST genes with one amino acid substitution in TodS might provide strain KL47 with a means of adaptation of the tod catabolic operon to various aromatic hydrocarbons.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.35 no.12
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• pp.1375-1381
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• 2011

Combustion processes in an optically-accessible single-cylinder heavy-duty diesel engine equipped with a highpressure common-rail injection system were investigated for JP-8 and diesel. Direct imaging and two-color thermometry were employed to verify the emission trend for both fuels. The combustion process was characterized by image analysis with focus on luminosity. The results of two-color thermometry were analyzed on the basis of the flame temperature and KL factor distribution. Analysis of the combustion process by direct imaging showed that the ignition delay was longer for JP-8 than for diesel, while the flame was extinguished rapidly. Analysis of the flame luminosity showed that the combustion intensity was higher for diesel and that the flame lasted for a longer duration in this case. Two-color thermometry results showed that the high-temperature region extended over a large area during JP-8 combustion, implying the formation of a large amount of $NO_x$. In addition, the KL factor showed low level over a large area and relatively homogeneous in the case of JP-8 combustion, which implied that less smoke was produced when using this fuel.

• Journal of the Korea Organic Resources Recycling Association
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• v.13 no.4
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• pp.89-99
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• 2005

The golf courses more than about 200 are operating in Korea. From the golf courses, a great amount of turfgrass clippings tend to increase, steadily. Materials used in the experiment were Creeping Bentgrass(CB), Kentucky Bluegrass(KB), Korean Lawngrass(KL), rice bran and composted chicken drop. Treatments are CB, KB, and KL. The temperature during the composting of all treatments increased rapidly and reached at the highest temperature($57.9^{\circ}C$, $67.8^{\circ}C$, $74.3^{\circ}C$) within 20 days, and then stabilized to the range of $35.2{\sim}41.6^{\circ}C$ at the 30th day. The pH values of all treatments decreased on the first day. However, they were increased rapidly after three days and decreased again on 10~20 days. The pH values of all treatments at the final day were stabilized to the low alkali levels. The contents of total carbon during the period of composting tend to decrease and total nitrogen was increased for factor of reduction of volume. CEC value of all treatments during the period of composting tends to increase. The round paper chromatogram of extracted solution of KL sample was the sharpest and clearest among all treatments. The G.I. values of CB, KB, and KL in 30th day of composting were about 95.1, 77.7, and 98.7 in germination test using chinese cabbage, respectively. Conclusively, all turfgrass clippings used in this experiment were composted well, suitable as composting products standardized by KSC. The maturity of the final compost samples is best in KL, followed by CB and KB treatments. The turfgrass compost can contribute to the plant cultivation for environment-friendly farm, and the results of this study can become the basic data of turfgrass clippings compost. Further research on the mixing ratio of each material is required to produce compost of good quality.

• Journal of the Institute of Convergence Signal Processing
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• v.11 no.4
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• pp.320-325
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• 2010

This paper is about the method and procedure to register the candidate sequentially in the face recognition system using the PCA(Principal Components Analysis). We use the method to update the principal components sequentially with the SKL algorithm which is improved R-SVD algorithm. This algorithm enable us to solve the re-training problem of the increase the candidates number sequentially in the face recognition using the PCA. Also this algorithm can use in robust tracking system with the bright change based to the principal components. This paper proposes the procedure in the face recognition system which sequentially updates the principal components using the SKL algorithm. Then we compared the face recognition performance with the batch procedure for calculating the principal components using the standard KL algorithm and confirms the effects of the forgetting factor in the SKL algorithm experimentally.

• Economic and Environmental Geology
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• v.39 no.5 s.180
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• pp.537-554
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• 2006

Water levels of thermal groundwater ($>30^{\circ}C$) were recorded from March 2002 to June 2006 at several monitoring wells within the Yuseong spa area. Using these data, we elucidated the long-term cyclic fluctuations of thermal groundwater levels with 1 year period. We also observed a noticeable water level variation with periods of 0.5, 1 and 7 days in most monitoring wells, which indicates relatively good hydraulic connectivity within the main hotspring area. By comparing water level variations among several wells, we found out that E-W and N-S trending geological structures should be an important control factor for emplacement and flow of thermal groundwater in the study area. It may be also inferred that geothermal source is highly associated with the hydraulic connectivity of aquifers at the Yuseong spa area.

• International Area Studies Review
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• v.22 no.4
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• pp.19-35
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• 2018

This paper is to estimate the total factor productivity(TFP) in the Korean manufacturing and service industries during the period 1975:1-2016:4 using the stochastic frontier analysis model. In order to analyze the determinants for the total factor productivity the paper estimates the industry-specific determinant elasticities of TFP using the autoregressive distributed model. The industry-specific determinants, which reflect the industrial structure and properties include markup, the ratio of capital to labor(KL), and the ratio of foreign intermediate goods (FIG) to industrial output. The average value for total factor productivity growth was estimated to be 0.0199 in manufacturing and 0.0063 in the service industry. The markup and KL elasticities of TFP were estimated to be 2.481 and 0.651 in manufacturing respectively and -1.403 and 0.042 in the service industry respectively. The empirical results suggest that the industrial markup and the ratio of capital to labor have had decisive effects on the changes in the total factor productivity in the Korean manufacturing and service industries during the period 1975:1-2016:4.

• YAKHAK HOEJI
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• v.54 no.3
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• pp.200-204
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• 2010

Nuclear factor-${\kappa}B$ (NF-${\kappa}B$) plays critical roles in physiological and pathological processes such as immune function, cellular growth, homeostasis, apoptosis, and inflammation. As part of our ongoing efforts to develop novel NF-${\kappa}B$ inhibitory agents, we reported that KL-1156 (6-hydroxy-7-methoxychroman-2-carboxylic acid phenylamide) exhibited potent inhibitory activity of NF-${\kappa}B$. For further structure-activity relationship, a series of 7-aryloxy-chroman-2-carboxylamide derivatives were synthesized to explore their inhibitory activities of NF-${\kappa}B$.

• Transactions of the Korean Society of Automotive Engineers
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• v.15 no.5
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• pp.38-47
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• 2007

Based upon temperature calibration using the diffusion flame, the temperature and soot concentration of the turbulent flame in a visualized Diesel engine's turbulent flow of flame was qualitatively measured. Two different heads were used to judge the effect of swirl ratio within the combustion chamber. It was possible to measure the highest temperature of the non-swirl head visualized engine which is approximately 2400K, and that the swirl head engine managed up to 2100K. Also, the more the pressure of the spray increases the more the temperature increases due to the improved combustion situation with respect to the visualized diesel engine soot. This experiment also revealed that the KL factor was high where the fuel collided with the walls of the combustion chamber. Moreover the KL factor was high on parts of the chamber where the temperature dropped rapidly.

• Korean Linguistics
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• v.77
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• pp.95-124
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• 2017

The purpose of this study is to examine aspects and causes of the change and disappearance in the Gangneung dialect vocabulary about costume. A typical example of linguistic factors that influence the change of costume vocabulary is competition with the standard language. However, costume as culture has a more powerful effect than linguistic factor. For example, the following factors lead to the disappearance: the disappearance of the referent, the inherent characteristics of the costume, the introduction of the new culture, and the change in values about costume.