• 제목/요약/키워드: KI12

검색결과 6,585건 처리시간 0.032초

A Study on a Statistical Matching Method Using Clustering for Data Enrichment

  • Kim Soon Y.;Lee Ki H.;Chung Sung S.
    • Communications for Statistical Applications and Methods
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    • 제12권2호
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    • pp.509-520
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    • 2005
  • Data fusion is defined as the process of combining data and information from different sources for the effectiveness of the usage of useful information contents. In this paper, we propose a data fusion algorithm using k-means clustering method for data enrichment to improve data quality in knowledge discovery in database(KDD) process. An empirical study was conducted to compare the proposed data fusion technique with the existing techniques and shows that the newly proposed clustering data fusion technique has low MSE in continuous fusion variables.

Assessment of Cellular Proliferation in Oral Verrucous Carcinoma and Well-Differentiated Oral Squamous Cell Carcinoma Using Ki67: A Non-Reliable Factor for Differential Diagnosis?

  • Zargaran, Massoumeh;Eshghyar, Nosratollah;Baghaei, Fahimeh;Moghimbeigi, Abbas
    • Asian Pacific Journal of Cancer Prevention
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    • 제13권11호
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    • pp.5811-5815
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    • 2012
  • Background: Non-invasive oral verrucous carcinoma (OVC) and invasive well-differentiated oral squamous cell carcinoma (OSCC) have similar histopathologic findings but different biological behavior. These two malignancies must be correctly differentiated by pathologists. The aim of this study was to determine immunohistochemical (IHC) expression of Ki67 in OVC and well-differentiated OSCC. Methods: Expression of Ki67 was evaluated by IHC in 15 cases of epithelial hyperplasia with no dysplasia (A group), 15 cases of OVC (B group), 12 cases of microinvasive OSCC(C group) and 15 cases of well-differentiated OSCC (D group). Results: There was a significant difference in Ki67 expression based on pattern distribution of immunostaining positive cells, with quantitative and semi-quantitative analyses, among the four groups ; also, between A group and each of the other three groups (P=0.0001). But there was no significant difference between B and C, C and D, and B and D groups (P>0.05). Conclusions: The three evaluation methods of Ki67 expression showed Ki67 (Mib-1) is not a good immunohistochemical marker to assess invasion status and differentiate OVC from well-differentiated OSCC; also, it cannot be used as a diagnostic tool to distinguish between variants of OSCC with similar grade.

Ki-67 Labeling Indices in 'Classic' versus 'Blastoid' Mantle Cell Lymphomas - Proposed Cutoff Values for Routine Diagnostic Workup

  • Pervez, Shahid;Haroon, Saroona;Awan, Dreema
    • Asian Pacific Journal of Cancer Prevention
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    • 제16권15호
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    • pp.6591-6594
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    • 2015
  • Background: Mantle-cell lymphoma (MCL) is a unique entity of peripheral B-cell lymphoma that has a discrete morphologic, immunologic, and genetic phenotype, with more common 'classic' and less frequent 'blastoid' and 'pleomorphic' variants, associated with an aggressive clinical course. The aim of this study was to analyze proliferation (Ki-67) indices of 'classic' (c-MCL) and 'blastoid' (b-MCL) variants of a cohort of MCL and to suggest cut off values for the Ki-67 proliferation index in these two subsets. Materials and Methods: MCL cases diagnosed over $4{\frac{1}{2}}$ years at Section of Histopathology, Department of Pathology and Laboratory Medicine, Aga Khan University Hospital, Karachi were retrieved and reviewed. Ki-67 labelling was scored and analysed. Results: A total of 90 of cases of MCL were scrutinized. Mean age ${\pm}SD$ was $60.2{\pm}12.5$ years and the male to female ratio was 4:1, with 67 (75%) cases of c-MCL and 23 (25%) cases of b-MCL. Most samples were lymph node biopsies (n=68), whereas the remainder were from various extranodal sites The mean Ki-67 proliferation index was $29.5%{\pm}14.4%$ in classic variants and $64.4{\pm}15.2%$ for the blastoid variant, the difference being statistically significant (p = 0.029). Conclusions: It was concluded that differential cut-off values of Ki-67 labeling may be used in more objective way to reliably classify MCL into classic or blastoid variants by diagnostic pathologists. We propose a < 40 proliferative index to be suggestive of c-MCL and one of > 50 for the blastoid variant.

뇌졸중 치료제인 한약의 효과 (The Effects of Herb Extracts in Cerebrovascular Accidental Patient)

  • 이미화;박형숙;최원철
    • 재활간호학회지
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    • 제3권2호
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    • pp.141-153
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    • 2000
  • The several Chinese herbs such as Soon-Ki-Hwal-Hyul-Tang, Bo-Yang-Hwan-O-Tang, Seong-Hyang-Jeong-Ki-San, So-Hap-Hyang-Won and O-Yak-Soon-Ki-San were extracted with water and then lyophilized. For identification of the effect of extracted herbs, they were medicated to 103 patients of cerebrovascular accident for 4 week. They were hospitalized in D-Oriental Medical Hospital from April to August in 1999. The herbs were extracted with water and lyophilized and then, used as samples. The medical history of each patient was detected and analyzed from their medical records. The results were as follows; 1) Each sample (Soon-Ki-Hwal-Hyul-Tang, Bo-Yang-Hwan-O-Tang, Seong-Hyang-Jeong-Ki-San, and O-Yak-Soon-Ki-San) was statistically significant differences of systolic blood pressure(t=4.22, P=0.0004; t=3.44, P=0.0028; t=2.11, P=0.0463; t=3.23, P=0.0052). The statistically significant difference of diastolic blood pressure showed by medicated with Soon-Ki-Hwal-Hyal-Tang, Seong-Hyang-Jeong-Ki-San, and O-Yak-Soon-ki-San (t=2.13, P=0.0459; t=2.68, P=0.0136; t=3.12, P=0.0066). 2) The statistically significant difference of the arm/leg-ROM showed by medicated with Soon-Ki-Hwal-Hyul-Tang, Bo-Yang-Hwan-O Tang, So-Hap-Hyang-Won(t=4.74/4.95, P=0.0002/0.0001; t=2.25/2.44, P=0.0368/0.0248; t=5.85/6.76, P=0.0001/0.0001). 3) In the verbal disorder, Soon-Ki-Hwal-Hyul-Tang, Bo-Yang-Hwan-O-Tang had statistically significant differences(t=4.50, P=0.0002; t=3.32, P=0.0036). 4) In the conscious disorder, Soon-Ki-Hwal-Hyul-Tang, Bo-Yang-Hwan-O-Tang, Seong-Hyang-Jeong-Ki-San, and So-Hap-Hyang-Won had statistically significant differences(t=6.32, P =0.0001; t=8.32, P=0.0001; t=3.74, P=0.0012; t=5.14, P=0.0001). 5) Bovine aortic endothelial cell (BAEC) were cultured in DMEM treating 0.01mg/ml, and 0.1mg/ml of each lyophilized samples for 24 hours. In BAECs were treated by 5 kinds of samples, the effect of So-Hyap-Hyang-Won induced syncytium of adjacent endothelial cells. It may induce the recovering of the damaged blood vessels in cerebrovascular accidental patient by angiogensis of endothelial cells. Therefore, it suggests that the medication of So-Hap-Hyang-Won will help to nursing care for cerebrovascular accidental patients.

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족관절 염좌에 SSP 전자침 요법을 병행한 동기침법(動氣鍼法)의 효과 (The Effects of Alphabet Exercise with SSP Electrotherapy on Lateral Ankle Sprain)

  • 심우진;류수민;신현대;우경하
    • 대한추나의학회지
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    • 제4권1호
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    • pp.89-98
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    • 2003
  • The multiple acupuncture techniques have been used to relieve the pain of lateral ankle sprain. Recently, early functional rehabilitation is emphasized in rehabilitative concepts using active ROM, facilitated proprioception, alphabet exercise and so forth. Similarly, in oriental rehabilition medicine, traditional movement technique called "Dong-Ki" has been used to relieve pain of ankle sprain. So we used "Dong-Ki" technique with SSP(silver spike point) electrotherapy transformed from alphabet exercise and evaluated the effects in method of randomized controlled trials. Methods : 27 outpatients with lateral ankle sprains were randomized into two groups : 15 samples and 12 controls. Sample group was treated with "Dong-Ki" technique(writing his name with foot) with SSP electrotherapy to relieve pain during additionally. "Dong-KI". Outcomes were measured by 10cm VAS and ankle circumference(cm). Results : In terms of VAS, Sample group had inclination of pain relieving but not significantly meaningful. In terms of ankle circumference measurement, Sample group showed significantly improved.

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$\ll$영추(靈樞).동수(動輸)$\gg$에 대한 연구(硏究)

  • 장대원;이남구;채우석
    • 대한한의학원전학회지
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    • 제12권2호
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    • pp.294-315
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    • 1999
  • $\ll$靈樞 動輸$\gg$ explains the way that the Arm Greater um Lung meridian, the Leg lesser urn kidney meridian and the Leg Yang-Myong Stomach meridian are keeping incessant pulsation, and the relation that these three meridians transport ant irrigate around the whole body. And also, when the meridian lines have been obstructed, the ki travels via shortcuts, in the course of spreading outer ki and inner ki around the whole body. Concretely speaking, in the first mapter it is explained the way that the Arm Greater urn Lung meridian pulses incessantly, in the second chapter, it is explained the way that the Leg Yang-Myong stomach meridian pulses incessantly, in the third chapter, the Leg Lesser urn kidney meridian pulses incessantly and in the fourth chapter, the movement of inner and outer ki are explained. But this chapter has many ancient letters and many parts omitted, so it is too hard to understand directly. Therefore we set to work with the view of helping to understand the original text more accurately by the reference of several editions and many commentarists' fruitful researches.

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SLS 공정을 이용한 산업용 SFF 시스템용 신소재 고분자분말 개발 (Development of New Polymer Powders for the Industrial SFF system by using SLS Process)

  • 방영길;최기섭;박창현;김형일;임병석;김동수
    • 대한기계학회:학술대회논문집
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    • 대한기계학회 2007년도 춘계학술대회A
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    • pp.1404-1409
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    • 2007
  • Polymers for laser sintering were needed in order to fabricate the articles with the three-dimensional duplication equipment of SLS (selective laser sintering) process. The thermal properties, particle size, distribution, and shape of polymer powder had a close relation with the processibility of laser sintering. In this study, we prepared new polymer powders with uniform size and higher bulk density by wet process. Wet process consists of several finely-controlled steps such as dissolution, nucleation, propagation and crystallization. Several additives were added to improve the thermal, rheological, and flow properties.

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