• 제목/요약/키워드: KFDA

검색결과 710건 처리시간 0.028초

Investigation of potential estrogenic activity of bioallethrin in vitro and in vivo assays

  • Kim, Soon-Sun;Rhee, Gyu-Seek;Lee, Rhee;Kwack, Seung-Jun;Lim, Kwon-Jo;Park, Chul-Hoon;Lee, Geun-Shik;Jeung, Eui-Bae;Kil, Kwang-Sup
    • 대한약학회:학술대회논문집
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    • 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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    • pp.173.2-174
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    • 2003

  • Many pesticides possess hormonal activity and have been thus classified as endocrine disruptors. Bioallethrin is one of the pyrethroids. synthetic derivatives of naturally occurring pyrethrins. These pyrethroids including bioallethrin have been developed as insectides due to their high insecticidal potency and low mammalian toxicity. Currently, bioallethrin is used to eradicate pests and insects in Korea, providing potential for human exposure. (omitted)

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Effect of Genistein on the Wnt Signaling Pathway and Cell Growth

  • Moon, Hyun-Ju;Ryu, Sung-Yeoul;Kang, Tae-Seok;Kang, Ho-ll;Kang, ll-Hyun;Kim, Tae-Sung;Hong, Jin;Han, Soon-Young;Choi, Kang-Yell;Kwon, Ki-Sung
    • 한국독성학회:학술대회논문집
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    • 한국독성학회 2005년도 춘계 국제심포지엄 및 학술대회
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    • pp.189-189
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    • 2005

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Effects of Benomyl and Lindane during late pregnancy in the rat

  • Moon, Hyun-Ju;Shin, Jae-Ho;Lee, Sujung;Kang, Il-Hyun;Kim, Tae-Sung;Hoon Bae;Ryu, Seung-Yeoul;Seok, Ji-Hyun;Ahn, Ji-Yeon
    • 한국독성학회:학술대회논문집
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    • 한국독성학회 2002년도 Molecular and Cellular Response to Toxic Substances
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    • pp.165-165
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    • 2002

  • These experiments tested whether exposure to benomyl (BN) or lindane (LD) during late pregnancy affect the development of reproductive tract in adult offspring. Timed pregnant Sprague Dawley rats (N=7∼8/treatment) were gavaged with LD (1, 5, or 10 mg/kg), BN (50, 250, or 500 mg/kg), or com oil on gestation days 15∼19.(omitted)

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Assessment of cytokine producing cells to discriminate between allergen and irritant in the local lymph node assay

  • Lee, Jong-Kwon;Byun, Jung-A;Park, Seung-Hee;Kim, Hyung-Soo;Park, Jae-Hyun;Ryu, Mi-Hyun;Park, Han-Jin;Juno H. Eom;Oh, Hye-Young
    • 한국독성학회:학술대회논문집
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    • 한국독성학회 2003년도 추계학술대회
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    • pp.124-124
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    • 2003

  • A murine local lymph node assay(LLNA) has been developed as an alternative method to guinea pig maximization test for contact sensitization potential. This study was carried out to investigate the potential use of cytokine producing cells to discriminate between allergens and irritant in the LLNA.(omitted)

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