• Title/Summary/Keyword: K-hospital

Search Result 43,080, Processing Time 0.055 seconds

Risk factors of ocular involvement in children with mitochondrial respiratory chain complex defect

  • Chae, Jung-Hyun;Lee, Jung-Hun;Kim, Kyo-Ryung;Byeon, Suk-Ho;Lee, Young-Mock;Kang, Hoon-Chul;Lee, Joon-Soo;Kim, Heung-Dong
    • Clinical and Experimental Pediatrics
    • /
    • v.53 no.12
    • /
    • pp.994-999
    • /
    • 2010
  • Purpose: Mitochondrial dysfunction can present with various symptoms depending on the organ it has affected. This research tried to analyze the ophthalmologic symptoms and ophthalmologic examination (OE) results in patients with mitochondrial disease (MD). Methods: Seventy-four patients diagnosed with mitochondrial respiratory chain complex defect with biochemical enzyme assay were included in the study. They were divided into 2 groups based on the OE results by funduscopy and were analyzed on the basis of their clinical features, biochemical test results, morphological analysis, and neuroimaging findings. Results: Thirty-seven (50%) of the 74 MD patients developed ophthalmologic symptoms. Abnormal findings were observed in 36 (48.6%) patients during an OE, and 16 (21.6%) of them had no ocular symptoms. Significantly higher rates of prematurity, clinical history of epilepsy or frequent apnea events, abnormal light microscopic findings in muscle pathology, diffuse cerebral atrophy in magnetic resonance imaging, and brainstem hyperintensity and lactate peaks in magnetic resonance spectroscopy were noted in the group with abnormal OE results. Conclusion: Although the ophthalmologic symptoms are not very remarkable in MD patients, an OE is required. When the risk factors mentioned above are observed, a more active approach should be taken in the OE because a higher frequency of ocular involvement can be expected.

A case report of generalized morphea treated with herbal medication and moxibustion

  • Lee, Hye Yoon;Kim, So Yeon;Cho, Min Kyoung;Choi, Jun Yong;Hong, Minna;Lee, Ji Hye;Lee, In;Hong, Jin Woo;Han, Chang Woo;Kwon, Jung Nam
    • The Journal of Korean Medicine
    • /
    • v.36 no.4
    • /
    • pp.104-113
    • /
    • 2015
  • A 56-year-old Korean female patient developed generalized morphea over three months. We focused on imbalance of the neuroendocrine-immune axis, mainly using Jiawei-Renshengyangrong-tang and Jiawei-Siqi-tang. Moxibustion on LU9 was conducted for skin symptoms. The patient's modified localized scleroderma skin severity index score decreased from 22 to 6 over 22 weeks of treatment and to 4 during a 3-month follow-up. Her verbal rating scale score for general symptoms decreased from 17 to 1 during the 22-week treatment.

Interventional Therapy for Renal Artery Pseudoaneurysms

  • Ji, Wen-Bin;Wang, Wei-Zheng;Sun, Song;Mi, Yu-Cheng;Xu, Qiong;Chen, Yi-Er;Yang, Song;Tao, Dan;Xu, Wei;Xu, Chao
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.13 no.4
    • /
    • pp.1595-1598
    • /
    • 2012
  • The aim of this study was to explore the angiographic diagnosis and embolization therapy for renal artery pseudoaneurysms due to acute urinary tract hemorrhage after conservative medical management failed. Seven out of ten cases had fever symptoms after the kidney surgery. The pseudoaneurysms were treated with gelatin sponge and (or) spring coil and the majority demonstrated rapid blockage of hemorrhage. Angiography diagnosis and trans catheter embolization are rapid, safe and effective methods for diagnosis and treatment of renal artery pseudoaneurysms.