• Journal of Chest Surgery
• /
• v.29 no.11
• /
• pp.1267-1269
• /
• 1996

Coronary artery bypass grafting without cardiopulmonary bypass is now one of accepted technique of myocardial revascularization. This technique is an alternative method for patients with lesions in the left anterior descending coronary artery and right coronary artery. We report a case of coronary artery bypass grafting without cardiopulmonary bypass or cardiac arrest.

• 대한생식의학회:학술대회논문집
• /
• 2002.11a
• /
• pp.98.2-99
• /
• 2002

• 대한생식의학회:학술대회논문집
• /
• 2006.06a
• /
• pp.156.1-156.1
• /
• 2006

• Tuberculosis and Respiratory Diseases
• /
• v.65 no.5
• /
• pp.416-420
• /
• 2008

Many classes of drug, such as antineoplastic drugs and antiarrhythmic drugs, have potential to induce interstitial lung disease. Herbal medicines are also believed to have the potential to induce pneumonitis. However, to our knowledge, there are no reports of pneumonitis caused by herbal medications in the Korean medical database. We report a case of recurrent pneumonitis caused by a self rechallenge of the Herbal medicine Bojungikgitang (Bu-Zhong-Yi-Qi-Tang : Hochu-ekki-to).

• Asian Pacific Journal of Cancer Prevention
• /
• v.13 no.7
• /
• pp.3223-3228
• /
• 2012

HMGN5 is a typical member of the HMGN (high mobility group nucleosome-binding protein) family which may function as a nucleosomal binding and transcriptional activating protein. Overexpression of HMGN5 has been observed in several human tumors but its role in tumorigenesis has not been fully clarified. To investigate its significance for human lung cancer progression, we successfully constructed a shRNA expression lentiviral vector in which sense and antisense sequences targeting the human HMGN5 were linked with a 9-nucleotide loop. Inhibitory effects of siRNA on endogenous HMGN5 gene expression and protein synthesis were demonstrated via real-time RT-PCR and western blotting. We found HMGN5 silencing to significantly inhibit A549 and H1299 cell proliferation assessed by MTT, BrdU incorporation and colony formation assays. Furthermore, flow cytometry analysis showed that specific knockdown of HMGN5 slowed down the cell cycle at the G0/G1 phase and decreased the populations of A549 and H1299 cells at the S and G2/M phases. Taken together, these results suggest that HMGN5 is directly involved in regulation cell proliferation in A549 and H1299 cells by influencing signaling pathways involved in cell cycle progression. Thus, our finding suggests that targeting HMGN5 may be an effective strategy for human lung cancer treatment.

• 대한핵의학회:학술대회논문집
• /
• 2000.05a
• /
• pp.67.2-67.2
• /
• 2000

• 대한핵의학회:학술대회논문집
• /
• 2000.05a
• /
• pp.73-73
• /
• 2000

• 대한생식의학회:학술대회논문집
• /
• 2004.11a
• /
• pp.68-69
• /
• 2004

• 대한핵의학회:학술대회논문집
• /
• 1992.06a
• /
• pp.184.2-184.2
• /
• 1992

• 대한생식의학회:학술대회논문집
• /
• 2007.06a
• /
• pp.144-144
• /
• 2007