• Title/Summary/Keyword: K-group

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A Research of MMPI Profile on Patients with Uterine Myoma and Adenomyosis Depanding on the Existence of Menorrhagia (자궁근종과 자궁선근증 환자에서 과다월경 증상 유무에 따른 MMPI 비교 연구)

  • Kim, Heung-Soo;Choi, Jae-Ho;Lee, Jin-Moo;Lee, Chang-Hoon;Cho, Jung-Hoon;Lee, Kyung-Sub;Jang, Jun-Bock
    • The Journal of Korean Obstetrics and Gynecology
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    • v.20 no.4
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    • pp.111-122
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    • 2007
  • Purpose: The purpose of this study is to make clear the difference of the mental state between formal menstruation group and menorragia group. Methods: The patients suffering from uterine myoma or adenomyosis answered about menstruation and did a blood test and MMPI. They were analyzed by Mann-Whitney U-test. Results: The D scale of complain of a menorrhagia group is higher than normal menstruation group. (p<0.05) According to blood test, The F scale of anemia group is higher than normal group.(p<0.05) The D scale of menorrhagia with anemia group is higher than normal menstruation without anemia group. (p<0.05) The MMPI score of complain of a menorrhagia group, anemia group, and menorrhagia with anemia group showed 1-2 profile type. The MMPI score of normal menstruation group, normal result of the blood test group, and menorrhagia with anemia group showed 1-3 profile type. Conclusion: regardless of the rxistence of anemia, the group with menorrhagia tends to show a state of depression than the control group.

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Cardiac Development and Cell Cycle

  • Koh, Keum-Nim;Lee, Seog-Jae;Lee, Ho-Keun;Ahn, Ji-Eun;Kim, Jae-Chol;Ha, Ki-Chan;Chae, Soo-Wan;Koh, Gau-Young
    • Proceedings of the Korean Biophysical Society Conference
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    • 1998.06a
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    • pp.13-13
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    • 1998
  • The molecular mechanisms that arrest cardiomyocytes in the cell cycle during postnatal period remain largely unknown. The activity of CDKs control cell cycle progression, and this activity is regulated positively and negatively by association of CDKs with cyclins and cyelin dependent kinase inhibitors (CKIs) respectively.(omitted)

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F93-A: A Inhibitor of Farnesyl Protein Transferase from Aspergillus fumigatus KL93

  • Kwon, Byoung-Mog;Lee, Seung-Ho;Jeong, Tae-Sook;Kim, Sung-Uk;Son, Kwang-Hee;Park, Diol;Kim, Young-Kook;Nam, Ji-Youn;Bok, Song-Hae
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1995.04a
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    • pp.66-66
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    • 1995
  • Mutated forms of the ras oncogenes are associated with about 30% of human tumors. The ras genes encode 21KDa proteins, called p21 or Ras, that are associated with the plasma membrane. FPTase is a dimeric enzyme that catalyses the transfer of the farnesyl group from farnesyl pyrophosphate onto cysteine 186 at the C-terminus of the Ras protein. This is mandatory process for triggering ras oncogene toward tumor formation. Therefore, selective inhibitors of FPTase have the potential to be used as antitumorgenic agents.

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Effects of Deep Abdominal Muscle Strengthening Exercises on Pulmonary Function and the Ability to Balance in Stroke Patients

  • Kang, Jeong-Il;Kim, Beom-Ryong;Park, Seung-Kyu;Yang, Dae-Jung;Jeong, Dae-Keun;Kim, Je-Ho
    • The Journal of Korean Physical Therapy
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    • v.27 no.4
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    • pp.258-263
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    • 2015
  • Purpose: This study investigated effects of deep abdominal muscle strengthening exercises on pulmonary function and the ability to balance in stroke patients and was conducted to propose an exercise program for improving cardiovascular function. Methods: Study subjects were 20 patients with hemiplegia due to stroke, who were divided into the deep abdominal muscle strengthening exercise group (experimental group), 10, and the control group, 10. Pulmonary function tests measured FVC and FEV1, dynamic balance ability was measured using TUG. Static and dynamic balance ability was measured using BBS. The experimental group performed exercises during a period of 6 weeks, 5 times a week for 40 minutes, whereas the control group did not participate in regular exercise. The difference before and after the exercise was compared using paired t-test, difference in exercise before and after between groups was ANCOVA and level of significance was set at ${\alpha}=0.05$. Results: The changes in FVC and FEV1 within the group showed a significant difference only in the experimental group (p<0.001) (p<0.01), between-group difference was statistically significant only in FVC and FEV1 changes in the experimental group (p<0.001). The TUG changes within the group showed a significant difference in the experimental group and control group (p<0.001) (p<0.05), while BBS changes showed a significant difference only in the experimental group. Between-group difference was statistically significant only in TUG and BBS changes in the experimental group. The experimental group showed a more effective significant difference than the control group (p<0.001). Conclusion: Can exercise involving a deep abdominal muscle strengthening program be applied in patients with stroke with difficulty in control of trunk and decreased breathing ability?

Effect of FC-GT Supplement on Body Fat and Lipid Metabolism in Rats

  • Woo, Myoung-Nam;Jeon, Seon-Min;Kim, Hye-Jin;Yeo, Ji-Young;Ha, Tae-Youl;Choi, Myung-Sook
    • Nutritional Sciences
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    • v.9 no.4
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    • pp.248-258
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    • 2006
  • The objective of this study was to investigate the effects of supplementation of an antiobese functional formula (FC-GT) on body weight and lipid metabolism in rats fed a high-fat diet. Three groups of male Sprague-Dawley rats were fed different diets for 6 weeks: normal control (NC), high-fat (HF), and high-fat supplemented with powdered antiobese functional formula (FC-GT) (5% wt/wt) groups. Although body weight was not significantly different among the groups, relative weights of epididymal and perirenal white adipose tissues were significantly lower in the FC-GT group than in the HF group. FC-GT supplementation significantly lowered the plasma total cholesterol and triglyceride concentrations, whereas it elevated the ratio of HDL-C/total-C and improved the atherogenic index. Hepatic cholesterol and triglyceride concentrations were significantly lowered in the FC-GT group compared to the HF group. The accumulation of hepatic lipid droplets and the epididymal white adipocyte size of the FC-GT group were diminished compared to the HF group. Hepatic HMG-CoA reductase activity was significantly lower in the FC-GT group than in the HF group. Plasma GPT activity was significantly lowered in the FC-GT group compared to the HF group. Additionally, fecal weight was significantly increased in the FC-GT group than in the HF group. In addition, contents of fecal triglyceride and cholesterol were significantly higher in the FC-GT group compared to the other groups. The antioxidant activities of hepatic SOD, CAT, and GR were significantly increased in the FC-GT group compared to the HF group. Hepatic mARS and plasma mARS levels were significantly lowered in the FC-GT group compared to the NC group. Accordingly, we conclude that supplementation of FC-GT improves plasma and hepatic lipid levels in high-fat fed rats.