• Applied Biological Chemistry
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• v.45 no.4
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• pp.212-217
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• 2002

We purified polyphenols from persimmon leaf and tested their biological activity. The 60% acetone extract was lyophilized and applied to test enzyme inhibition of glucosyltransferase and tyrosinase. GTase was 82.4% inhibited at $1.8{\times}10^{-1}$ mg/ml and tyrosinase 21.7% inhibited at 0.8 mg/ml. The acetone extract was fractionated into F-1, 2, 3, 4, 5 by Sephadex Q-50 gel filtration and the fraction-1 and 2 showed higher enzyme inhibition activity than the other fractions. To the Proteinase K treatment and autoclaving of the two fractions had no effect on the enzyme activity, but these results suggested that active fraction was not protein but phenol ring completed compounds. By Sephadex LH-20, MCI-gel and Bondapak $C_{18}$ column chromatographies, compouds 1, 2, 3 and 4 from F-1 fraction, compounds 5 and 6 from F-2 fraction and compounds 7 , 8 from F-3 fraction were purified and re-crystallized. The purified compounds was assumed to be condensed tannins of frame flavan-3-ol frame on the basis of color reagent reaction and to be a mixture of monomer, dimer and trimer according to TLC analysis.

• Progress in Medical Physics
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• v.24 no.4
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• pp.220-229
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• 2013

Respiratory-induced dynamic tumors render free-breathing cone-beam computed tomography (FBCBCT) images with motion artifacts complicating the task of quantifying the internal target volume (ITV). The purpose of this paper is to study the visibility of the revealed ITV when the imaging dose parameters, such as the kVp and mAs, are varied. The $Trilogy^{TM}$ linear accelerator with an On-Board Imaging ($OBI^{TM}$) system was used to acquire low-imaging-dose-mode (LIDM: 110 kVp, 20 mA, 20 ms/frame) and high-imaging-dose-mode (HIDM: 125 kVp, 80 mA, 25 ms/frame) FBCBCT images of a 3-cm diameter sphere (density=0.855 $g/cm^3$) moving in accordance to various sinusoidal breathing patterns, each with an unique inhalation-to-exhalation (I/E) ratio, amplitude, and period. In terms of image ITV contrast, there was a small overall average change of the ITV contrast when going from HIDM to LIDM of $6.5{\pm}5.1%$ for all breathing patterns. As for the ITV visible volume measurements, there was an insignificant difference between the ITV of both the LIDM- and HIDM-FBCBCT images with an average difference of $0.5{\pm}0.5%$, for all cases, despite the large difference in the imaging dose (approximately five-fold difference of ~0.8 and 4 cGy/scan). That indicates that the ITV visibility is not very sensitive to changes in imaging dose. However, both of the FBCBCT consistently underestimated the true ITV dimensions by up to 34.8% irrespective of the imaging dose mode due to significant motion artifacts, and thus, this imaging technique is not adequate to accurately visualize the ITV for image guidance. Due to the insignificant impact of imaging dose on ITV visibility, a plausible, alternative strategy would be to acquire more X-ray projections at the LIDM setting to allow 4DCBCT imaging to better define the ITV, and at the same time, maintain a reasonable imaging dose, i.e., comparable to a single HIDM-FBCBCT scan.

• Structural Engineering and Mechanics
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• v.18 no.4
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• pp.389-410
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• 2004

In this study, theoretical and experimental results are presented which were obtained during an investigation of the influence of the $P-{\Delta}$ effect that was caused by the simultaneous changing of the axial load P of the column and the lateral displacement ${\Delta}$ in the external beam-column joints. The increase or decrease of ${\Delta}$ was simultaneous with the increase or decrease of the axial compression load P and caused an additional influence on the aseismic mechanical properties of the joint. A total of 12 reinforced concrete exterior beam-column subassemblies were examined. A new model, which predicts the beam-column joint ultimate shear strength, was used in order to predict the seismic behaviour of beam-column joints subjected to earthquake-type loading plus variable axial load and $P-{\Delta}$ effect. Test data and analytical research demonstrated that axial load changes and $P-{\Delta}$ effect during an earthquake cause significant deterioration in the earthquake-resistance of these structural elements. It was demonstrated that inclined bars in the joint region were effective for reducing the unfavourable impact of the $P-{\Delta}$ effect and axial load changes in these structural elements.

• Proceedings of the Korean Society for Technology of Plasticity Conference
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• 2009.05a
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• pp.187-190
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• 2009

Recently, automotive companies have invested in vehicle weight reduction and clean car development because of oil price rises and environmental problems. In particular, USA car makers have developed the vehicle spending 1 liter per 34km complying with PNGV(Partnership for a new generation of vehicle) and Europe car makers have developed the vehicle spending 3 liters per 100km. The USA government announced "The green car policy" in order to boost production of more fuel effective cars in 2009. According to the policy, it will be restricted to sell the car which spends more than 1 liter per 14.9km by 2020. To satisfy the current situations on automotive market, hydroforming technology has widely adapted vehicle structures such as engine cradle, chassis frame, A pillar, radiator support, etc. However, automotive companies have to consider formability and performance to improve and maximize the benefit from this technology in advance of detail design. The paper deals with one of the vehicle weight reduction methods using tube hydroforming technology and platform commonality in front suspension. FEA simulation is also introduced to evaluate hydro-formability and NVH performance at the beginning of design stage which is the best way to reduce the failure cost.

• Bulletin of the Korean Chemical Society
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• v.34 no.1
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• pp.143-148
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• 2013

Novel titanium containing solid core mesoporous shell silica has been synthesized by using octadecyltrichloro silane and triethylamine. The synthesized material was characterized by various physicochemical techniques. The mesoporous character of the material has been revealed from PXRD studies. The presence of octadecyltrichloro silane and triethylamine in the sample has been confirmed from EDAX studies. TG/DTA analysis reveals the thermal characteristics of the synthesized material. The presence of titanium in the frame work and its coordination state has been studies by UV-vis DR studies and XPS analysis. Chemical environment of Si in the framework of the material has been studied by $^{29}SiMASNMR$ studies. The surface area of the material is found to be around $550\;m^2g^{-1}$ and pore radius is of nano range from BET analysis. The spherical morphology and particle size of the core as well as shell has been found to be 300 nm and 50 nm respectively from TEM analysis. The catalytic application of this material towards the synthesis of caprolactam from cyclohexanone in presence of hydrogen peroxide through ammoxidation reaction has been investigated. The optimum conditions for the reaction have been established. The plausible mechanism for the formation of core silica and conversion of cyclohexanone has been proposed.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2003.11a
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• pp.388-391
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• 2003

The properties of these detectors can be controlled by electronics and exposure conditions. Flat-panel detectors for digital diagnostic imaging convert incident x-ray images to charge images. Flat panel detectors gain more interest real time medical x-ray imaging. Active area of flat panel detector is $14{\times}17$ inch. Detector is based on a $2560{\times}3072$ away of photoconductor and TFT pixels. X-ray conversion layer is deposited upper TFT array flat panel with a 500m by thermal deposition technology. Thickness uniformity of this layer is made of thickness control technology(5%) of thermal deposition system. Each $139m{\times}139m$ pixel is made of thin film transistor technology, a storage capacitor and charge collection electrode having geometrical fill factor of 86%. Using the separate driving system of two dimensional mosaic modules for large area, that is able to 4.2 second per frame. Imaging performance is suited for digital radiography imaging substitute by conventional radiography film system..

• Nuclear Engineering and Technology
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• v.54 no.2
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• pp.709-731
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• 2022

Loss of fracture resistance due to thermal aging degradation is a potential limiting factor affecting the long-term (80+ year) viability of nuclear reactors. To evaluate the effects of decades of aging in a practical time frame, accelerated aging must be employed prior to mechanical characterization. In this study, a variety of chemically and microstructurally diverse austenitic stainless steels were aged between 0 and 30,000 h at 290-400 ℃ to simulate 0-80+ years of operation. Over 600 static fracture tests were carried out between room temperature and 400 ℃. The results presented include selected J-R curves of each material as well as K_0.2mm fracture toughness values mapped against aging condition and ferrite content in order to display any trends related to those variables. Results regarding differences in processing, optimal ferrite content under light aging, and the relationship between test temperature and Mo content were observed. Overall, it was found that both the ferrite volume fraction and molybdenum content had significant effects on thermal degradation susceptibility. It was determined that materials with >25 vol% ferrite are unlikely to be viable for 80 years, particularly if they have high Mo contents (>2 wt%), while materials less than 15 vol% ferrite are viable regardless of Mo content.

• The Journal of the Acoustical Society of Korea
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• v.37 no.2
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• pp.110-117
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• 2018

In this paper, we propose a low delay window switching MDCT (Modified Discrete Cosine Transform) method for speech/audio coder. The window switching algorithm is used to reduce the degradation of sound quality in non-stationary trasient duration and to reduce the algorithm delay by using the low delay TDAC (Time Domain Aliasing Cancellation). While the conventional window switching algorithms uses overlap-add with different lengths, the proposed method uses the fixed overlap add length. It results the reduction of algorithm delay by half and 1 bit reduction in frame indication information by using 2 window types. We apply the proposed algorithm to G.729.1 based on MDCT in order to evaluate the performance. The propose method shows the reduction of algorithm delay by half while speech quality of the proposed method maintains same as the conventional method.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.22 no.3
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• pp.513-519
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• 2018

OFDM modulation has been used for a transmission scheme in 4G LTE (Long Term Evolution) and Wi-Fi systems to mitigate the effects of frequency selective fading channels. An OFDM modulation is a block transmission scheme because an OFDM symbol consists of multiple subcarriers with narrow bandwidth. Therefore, all OFDM symbols in a frame should be filled out with data and padding bits. Depending on the amount of data, more padding bits than information bits can occupy the last OFDM symbol. Such inefficiency causes the loss of throughput. To overcome this problem, an efficiency padding method is proposed by using the property of DFT (Discrete Fourier Transform). In the proposed method, symbol duration of the last symbol is changed depending on the number used data subcarriers in the last symbol. With numerical evaluation, it is examined that throughput enhancement achieved by the proposed method can be about 20% depending a transmission scheme and data length.

• Journal of Microbiology and Biotechnology
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• v.20 no.10
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• pp.1403-1414
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• 2010

Aspergillus awamori BTMFW032, isolated from sea water, produced tannase as an extracellular enzyme under submerged culture conditions. Enzymes with a specific activity of 2,761.89 IU/mg protein, a final yield of 0.51%, and a purification fold of 6.32 were obtained after purification through to homogeneity, by ultrafiltration and gel filtration. SDS-PAGE analyses, under nonreducing and reducing conditions, yielded a single band of 230 kDa and 37.8 kDa, respectively, indicating the presence of six identical monomers. A pI of 4.4 and a carbohydrate content of 8.02% were observed in the enzyme. The optimal temperature was found to be $30^{\circ}C$, although the enzyme was active in the range of $5-80^{\circ}C$. Two pH optima, pH 2 and pH 8, were recorded, although the enzyme was instable at a pH of 8, but stable at a pH of 2.0 for 24 h. Methylgallate recorded maximal affinity, and $K_m$ and $V_{max}$ were recorded at $1.9{\times}10^{-3}$M and 830 ${\mu}Mol$/min, respectively. The impacts of a number of metal salts, solvents, surfactants, and other typical enzyme inhibitors on tannase activity were determined in order to establish the novel characteristics of the enzyme. The gene encoding tannase, isolated from A. awamori, was found to be 1.232 kb, and nucleic acid sequence analysis revealed an open reading frame consisting of 1,122 bp (374 amino acids) of one stretch in the -1 strand. In silico analyses of gene sequences, and a comparison with reported sequences of other species of Aspergillus, indicate that the acidophilic tannase from marine A. awamori differs from that of other reported species.