• Title/Summary/Keyword: K-6

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Effect of 6-Aminonicotinamide on the Levels of Some Metabolites and Related Enzymes in Rabbit Serum (6-Aminonicotinamide가 토끼혈청내 효소 및 대사물질에 미치는 영향)

  • Park, In-Koo;Lee, Chul-Seung;Lee, Seung-Hoon;Song, Yoon-Kyung;Shin, Sook
    • The Korean Journal of Zoology
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    • v.33 no.4
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    • pp.493-498
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    • 1990
  • The effects of an antimetabolite, 6-aminonicotinamide (6-AN) on the levels of enzymes and metabolites in rabbit serum were investigated. The intraperitoneal administration of 6-AN (multiple doses of l5mg/kg body weight) gave tise to a remarkable increase in glucose and cholesterol levels but did not exert any appreciable influence on the concentration of albumin and total protein. Alkaline phosphatase activity was significantly reduced by administration of 6-AN, whereas creatine phophokinase, serum glutamic oxaloacetate transaminase and serum glutamic pyruvate transaminase activities were matkedly enhanced. Nevettheless, the levels of Ca, P, Na, K, Cl and Co were not affeded to any extent by 6-AN.

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A Design of an Abnormal Traffic Control Framework in IPv6 Network (IPv6 네크워크 환경에서의 비정상 트래픽 제어 프레임워크 설계)

  • Kim, Ka-Eul;Kang, Seong-Goo;Kim, Jae-Kwang;Ko, Kwang-Sun;Kang, Young-Hyeok;Eom, Young-Ik
    • Proceedings of the Korea Information Processing Society Conference
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    • 2005.05a
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    • pp.1103-1106
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    • 2005
  • IPv4 프로토콜의 주소 고갈 문제를 해결하기 위하여 IPv6 프로토콜이 제안되었고 한국전산원의 발표에 의하면 2010년 이후에는 IPv6 프로토콜이 광범위하게 사용될 것이라고 한다. 이러한 IPv6 프로토콜은 IPv4 프로토콜의 단점들을 해결하기 위하여 ND(Neighbor Discovery) 메커니즘, 주소자동설정, IPsec 등의 기술을 지원하며, 특히 IPv6 프로토콜은 보안 문제를 해결하기 위해서 인증, 데이터 무결성 보호를 위한 IPsec 기술을 사용한다. 이러한 IPsec 기술은 패킷 정보를 보호하기 위한 목적으로 사용되기 때문에 불특정 다수의 사용자를 대상으로 하는 네트워크에 행해지는 분산 서비스 거부 공격과 같은 비정상 대용량 트래픽에 대한 탐지 및 차단에 어려움이 있다. 현재 IPv6 프로토콜을 지원하는 네트워크 공격 대응 기술로 IPv6 네트워크용 방화벽/침입탐지 시스템이 개발되어 제품으로 판매되고 있지만, 대용량의 비정상 트래픽 대응 기술을 탐지하고 차단하기에는 한계가 있다. 본 논문에서는 IPv6 네트워크 환경에서 이러한 대용량의 비정상 트래픽을 제어할 수 있는 프레임워크를 제시한다.

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Optical properties of undoped and $Zn_4SnSe_6$ and $Zn_4SnSe_6:Co^{2+}$ Single Crystals ($Zn_4SnSe_6$$Zn_4SnSe_6:Co^{2+}$단결정의 광학적 특성연구)

  • Kim, Nam-Oh;Kim, Hyung-Gon;Kim, Byung-Chul;Kim, Myeong-Soo;Oh, Guem-Kon
    • Proceedings of the KIEE Conference
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    • 2002.07c
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    • pp.1599-1602
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    • 2002
  • $Zn_4SnSe_6$ and $Zn_4SnSe_6:Co^{2+}$ single crystals were by the chemical transport reaction method. They crystallized in the monoclinic structure. The direct energy band gaps of the $Zn_4SnSe_6$ and $Zn_4SnSe_6:Co^{2+}$ single crystals at 289K were found to be 2.146eV and 2.042eV. Optical absorption due to impurity in the $Zn_4SnSe_6:Co^{2+}$ single crystal was observed and described as originating from the electron transition between energy leveles of $Co^{2+}$ sited at $T_d$ symmetry point.

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Preparation and Properties of Poly(ethylene terephthalate)(PET)/Polyamide-6(PA6) Alloy Fibers using Epoxy as a Reactive Compatibilizer: I. Effect of Epoxy on the Phase Separation of PET/PA6 Alloys (에폭시를 반응성 상용화제로 사용하여 제조한 폴리에틸렌테레프탈레이트와 폴리아미드-6 알로이 섬유의 구조와 성질: 1. 알로이의 상분리에 미치는 에폭시의 효과)

  • Zhou, Jing;Min, Byung-Gil;Lim, Mok-Keun;Lee, Kwang-Sang;Yu, Yeong-Chool;Han, Jae-Sung
    • Textile Coloration and Finishing
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    • v.24 no.2
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    • pp.145-151
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    • 2012
  • Polymer alloys of poly(ethylene terephthalate)(PET) and nylon6(PA6) which were not miscible each other by themselves were successfully prepared through melt compounding using a twin-screw extruder by utilizing epoxy as reactive compatibilizer. At the epoxy(DGEBA) amount of 0.5~2wt%, the domain size(average diameter) of the discontinuous phase could be reduced up to 0.2${\mu}m$ from 1-5${\mu}m$ that of the simple blend without epoxy. The reaction was presumed to happen mostly at interphase from the result of maximum increase of melt viscosity at the middle range of PET/PA6 blend ratio. It is expected that alloy fibers of PET/epoxy/PA6 with enough mechanical strength for use can be prepared.

Expression of CYP2A6, CYP2D6 and CYP4A11 Polymorphisms in COS7 Mammalian Cell Line

  • Lee, Hye-Ja;Park, Mi-Kyung;Park, Young-Ran;Kim, Dong-Hak;Yun, Chul-Ho;Chun, Young-Jin;Shin, Hee-Jung;Na, Han-Sung;Chung, Myeon-Woo;Lee, Chang-Hoon
    • Toxicological Research
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    • v.27 no.1
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    • pp.25-29
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    • 2011
  • The cytochrome P450 (P450, CYP) are the superfamily of heme-containing monooxygenase enzymes, found throughout all nature including mammals, plants, and microorganisms. Mammalian P450 enzymes are involved in oxidative metabolism of a wide range of endo- and exogenous chemicals. Especially P450s involved in drug metabolisms are important for drug efficacy and polymorphisms of P450s in individuals reflect differences of drug responses between people. To study the functional differences of CYP2A6, CYP2D6, and CYP4A11 variants, we cloned the four CYP2A6, three CYP2D6, and three CYP4A11 variants, which were found in Korean populations, in mammalian expression vector pcDNA by PCR and examined their expressions in COS-7 mammalian cells using immunoblots using P450 specific polyclonal antibodies. Three of four CYP2A6, two of three CYP4A11, and two of three CYP2D6 variants showed expressions in COS-7 cells but the relative levels of expressions are remarkably different in those of each variants. Our findings may help to study and explain the differences between functions of CYP variants and drug responses in Korean populations.

Photovoltaic Effects of the p$\cdot$Si-Electrolyte Junction (p$\cdot$Si-전해질 접합의 광기전력 효과)

  • Han, Seok-Yong;Kim, Yeon-Hui;Kim, Hwa-Taek
    • Journal of the Korean Institute of Telematics and Electronics
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    • v.19 no.6
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    • pp.52-54
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    • 1982
  • p·Si-전해질 접합을 전해질로 6N H2SO4, 6N H2SO4(Ti3+), 6N H2SO4(Ti4+), 6N H2SO4(Ti4+/Ti3+)을 사용하여 만들었다. 이들 전해질중 6N H2SO4(Ti4-/Ti3+)을 사용할 때 p·Si 광음극이 안정하게 동학하며 높은 광전 감도를 가지고 있었다. p·Si-electrolyte junction are prepared by using p·Si photocatode in four different electrolytes such as 6N H2SO4, 6N H2SO4(Ti3+), 6N H2SO4(Ti4+), 6N H2SO4(Ti4+/Ti3+) respectively. Among those electrolytes 6N H2SO4(Ti4-/Ti3+) shows very good results, in which p·Si photocathode is stable.

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Implementaion of 6to4 Mechanism based on Linux (리눅스 기반의 6to4 연동 메커니즘 설계 및 구현)

  • Lee, Sang-Do;Shin, Myung-Ki;Kim, Hyoung-Jun
    • Proceedings of the Korea Information Processing Society Conference
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    • 2005.11a
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    • pp.1331-1334
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    • 2005
  • 6to4 는 IPv6 을 지원하지 않는 IPv4 네트워크에 연결되어 있는 고립된 IPv6 네트워크의 상의 호스트들이 자동 터널링 방식을 통해 순수한 IPv6 네트워크나 6to4 로 구성된 네트워크상의 노드들과 통신할 수 있는 기술이다. 이 기술은 국제 민간 표준화 기구인 IETF 의 NGTrans 워킹 그룹에 의하여 표준화된 IPv6 전환 기술 중에 하나이며 독립적으로 구성된 IPv6 망 간의 통신을 하는 경우에 널리 사용될 것으로 예상이 된다. 본 논문은 IPv6 전환 기술 중 하나인 6to4 를 리눅스 환경에서 구현한 소프트웨어 모듈에 관한 설계 및 운용에 관한 것이다.

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A Kinetic Study of Thermal Degradations of Chitosan/Polycaprolactam Blends

  • Liao, Shen-Kun;Hung, Chi-Chih;Lim, Ming-Fung
    • Macromolecular Research
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    • v.12 no.5
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    • pp.466-473
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    • 2004
  • We have used FT-IR spectra to explain the effects of hydrogen bonding between chitosan and polycaprolactam (PA6). A dynamic mechanical analysis study suggested that the optimum chitosan and PA6 miscibility under the conditions of this experiment were obtained at a blending ratio of 40:60. We studied the thermal degradation of chitosan blended with PA6 (chitosan/PA6) by thermogravimetric analysis and kinetic analysis (by the Ozawa method). Dry chitosan and PA6 exhibited a single stage of thermal degradation and chitosan/PA6 blends having> 20 wt% PA6 exhibited at least two stages of degradation. In chitosan/PA6 blends, chitosan underwent the first stage of thermal degradation; the second stage proceeded at a temperature lower than that of PA6, because the decomposition product of chitosan accelerated the degradation of PA6. The activation energies of the blends were between 130 and 165 kJ/mol, which are also lower than that of PA6.

Effect of Flywheel Weight on Engine Performance for the Small Diesel Engine (Flywheel의 중량(重量)이 소형(小型) 디젤기관(機關)의 성능(性能)에 미치는 영향(影響))

  • Jung, Hae Kook;Kim, Sung Rai;Myung, Byung Soo
    • Korean Journal of Agricultural Science
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    • v.15 no.2
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    • pp.143-152
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    • 1988
  • This study was conducted to obtain basic data which affected engine performance of the power tiller being widely used in the rural area. Among the various factors affected engine performance, only flywheel weight was considered as the major factor in this study. Fuel consumption ratio, motoring loss, torque, vibration and mechanical efficiency of the engine tested were measured and analyzed on the four levels of flywheel weight (32.2, 29.7, 26.4, 24.2 kg). The results obtained were as follows: 1. The maximum output of 6 and 7.5 kW engine was 7.43 kW and 7.85 kW respectively. When flywheel weight was reduced from 32.2 kg to 24.2 kg, output power of the engine was increased 0.27 kW in 6 kW engine and increased 0.39 kW in 7.5 kW engine. 2. The fuel consumption ratio was decreased from 300.8 to 296.8 g/kW-hr in 6 kW engine and decreased from 313.6 to 312.8 g/kW-hr in 7.5 kW engine when the flywheel weight was reduced from 32.2 kg to 24.2 kg. 3. The mechanical efficiencies of the engine was increased from 76.1 to 76.8% in 6 kW engine and increased from 76.7 to 77.0% in 7.5 kW engine when the flywheel weight was reduced from 32.2 kg to 24.2 kg. 4. When the flywheel weight was reduced from 32.2 kg to 24.2 kg, a tendency of a little decrease of vibration at X- and Z-axis in 6 kW engine and of a little increase of vibration at Y-axis in 6 kW engine and all directions in 7.5 kW engine was observed. 5. Motoring losses was decreased from 2.33 to l.76 kW in 6 kW engine and decreased from 2.46 to 1.84 kW in 7.5 kW engine when the flywheel weight was reduced from 32.2 kg to 24.2 kg. From the above results and the flywheel weight calculated theoretically, it was recommendable that the flywheel weight should be reduced about 7 kg in 6 kW engine and about 10 kg in 7.5 kW engine, respectively.

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Artificial Oxidation of Cysteine Residues in Peroxiredoxin 6 Detected by Twodimensional Gel Electrophoresis and Capillary Liquid Chromatography-Electrospray Mass Spectrometry

  • Kimata, Junko;Shigeri, Yasushi;Yoshida, Yasukazu;Niki, Etsuo;Kinumi, Tomoya
    • Mass Spectrometry Letters
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    • v.3 no.1
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    • pp.10-14
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    • 2012
  • Artificially oxidized cysteine residues in peroxiredoxin 6 (Prx6) were detected by electrospray interface capillary liquid chromatography-linear ion trap mass spectrometry after the preparation of two-dimensional gel electrophoresis (2D-GE). We used Prx6 as a model protein because it possesses only two cysteine residues at the 47th and 91st positions. The spot of Prx6 on 2D-GE undergoes a basic (isoelectric point, pI 6.6) to acidic (pI 6.2) shift by exposure to peroxide due to selective overoxidation of the active-site cysteine Cys-47 but not of Cys-91. However, we detected a tryptic peptide containing cysteine sulfonic acid at the 47th position from the basic spot and a peptide containing both oxidized Cys-47 and oxidized Cys-91 from the acidic spot of Prx6 after the separation by 2D-GE. We prepared two types of oxidized Prx6s: carrying oxidized Cys-47 (single oxidized Prx6), and other carrying both oxidized Cys-47 and Cys-91 (double oxidized Prx6). Using these oxidized Prx6s, the single oxidized Prx6 and double oxidized Prx6 migrated to pIs at 6.2 and 5.9, respectively. These results suggest that oxidized Cys-47 from the basic spot and oxidized Cys-91 from the acidic spot are generated by artificial oxidation during sample handling processes after isoelectric focusing of 2D-GE. Therefore, it is important to make sure of the origin of cysteine oxidation, if it is physiological or artificial, when an oxidized cysteine residue(s) is identified.