• Korean Journal of Food Science and Technology
• /
• v.30 no.4
• /
• pp.823-826
• /
• 1998

It has been reported that alginic acid hydrolysate retains antimicrobial activity but the enzyme which hydrolyze alginic acid is not developed for industrial use. The authors developed chemical method for hydrolyzing alginic acid. For preparing alginic acid hydrolysate, equal quantity of alginic acid and ascorbic acid were added to water. Then the solution was heated at $121^{\circ}C$ for $20{\sim}30{\;}minutes$. The 4% solution of alginic acid hydrolysate was revealed relative viscosity 1.05, pH 3.2 and opaque whitish-yellow color. By addition of this hydrolysate to nutrient broth with the concentration of 0.1%, the growth of Bacillus sp. isolated from fish meat paste products was inhibited. The fish meat paste products containing 0.3% alginic acid hydrolysate prepared were prolonged their shelf life by 1 day stored at $30^{\circ}C$, 2 days at $20^{\circ}C$ and 4 days at $15^{\circ}C$.

• Journal of Nutrition and Health
• /
• v.9 no.3
• /
• pp.18-25
• /
• 1976

To explain the change of the pungent principles of red pepper, capsaicin, during storage, the relation between infecting mold and capsaicin was studied. Results obtained were summarized as follows; 1. Superior strains which showed good growth and high decomposition activity in their culture broths, Aspergillus oryzae and Aspergillus sp. KF-7 were obtained from the contaminated red pepper fruits. 2. The weight of dry matter was increased at low concentration of capsaicin $(2{\sim}3{\mu}g/ml)$ but it was decreased at high concentration. 3. The residual capsaicin in the culture medium was reduced as half as such after 1 week, and almost disappeared after 2 weeks. At $30^{\circ}C$ and $pH\;7{\sim}9$ of culturing condition, the amounts of reducing capsaicin reached to the maximum. 4. At ground red pepper fruits as culture medium, Aspergillus sp. KF-7 could not glow at all, but Aspergillus oryzae showed good growth at 13% of moisture contents and the residual of capsaicin of red pepper fruits after 40days of cultivation time was 45%. 5. At ground red pepper fruits seed as culture medium, Aspergillus oryzae and Aspergillus sp. KF-7 showed good growth, and the residual of capsaicin after 4 weeks of cultivation time was 55% and 38% respectively.

• Korean Journal of Fisheries and Aquatic Sciences
• /
• v.25 no.3
• /
• pp.229-235
• /
• 1992

Fish protein hydrolysates(FPH) prepared from defatted mackerel meal by proteases such as complex enzymes, bromelain, alcalase, $\alpha-chymotrypsin,$ trypsin, papain and pepsin were tested for inhibitory activity against angiotensin-I converting enzyme(ACE). Among proteases tested, the hydrolysates obtained from the treatment of complex enzymes or bromelain showed relatively higher activity. ACE inhibitory activity of the hydrolysates increased until hydrolysis of 8 hrs, and was stable by heat treatment for 20min at $100^{\circ}C.$ From the profiles of fractionation of the hydrolysates with Bio-gel P-2, the most active fraction had about MW 1,450 and it's amino acid was abundant in Asp, Glu, Lys, Leu, Val and Ala. $IC_{50}\;(amounts\;of\;inhibitors\;needed\;for\;50\%\;inhibition)$ of the active fraction of the hydrolysates obtained from the treatment of complex enzyme and bromelain was 90 and $130 {\mu}g,$ respectively.

• Journal of the Korean Society of Food Science and Nutrition
• /
• v.7 no.1
• /
• pp.35-39
• /
• 1978

In order to understand the diets of Gwangju city resident, nutrition survey was carried out through four years from 1974 to 1977. 1. Average intake of nutritional elements for an adult per day was 580. 25gr in 1974, 583.62gr in 1975, 599.13gr in 1976, and 597.72gr in 1977. 2. Average calorie distribution of the nutritional elements per adult per day was 13.51% protein, 4.70% fat and 81.08% carbohydrate in 1974; 11.6% protein, 7.1% fat and 81.3% carbohydrate in 1975; 15.0% protein, 4.9% fat and 80.1 % carbohydrate in 1976; 13.79% protein, 4.3% fat, and 82% carbohydrate in 1977. 3. The ratio of the animal protein to total protein consumed was 20.01% in 1974, 25.89% in 1975, 26.01% in 1976, and 29.38% in 1977. 4. In aspect of calorie, taken-in calorie was 2456.91 cal in 1974, 2515.10 cal in 1975, 2544.58 cal in 1976, and 2519.08 cal in 1977. However most of calorie were lower than the R.D.A. (3000cal). 5. The amount of ingested protein was 78.18 gr in 1974, 87.61 gr in 1975, 89,93 gr in 1976, and 81.65gr in 1977. The amount was higher than the R.D.A. (80gr) except 1974’s protein amount. 6. As for fat consumption, it was 27.18 gr in 1974, 40.96gr in 1975, 29.61gr in 1976, and 25.64gr in 1977. But these values were much lower than the R.D.A. (40gr) except for 1975’s. 7. In aspect of the minerals (Fe, Ca), intake of Ca was 462.34mg in 1974, 400.07 mg in 1975, 488.14 mg in 1976 and 440.95mg in 1977. The consumption of Ca was lower than the R.D.A. (600mg). Fe was 10.27mg in 1974, 8.54mg in 1975, 11.36mg in 1976 and 20.84mg in 1977. Most of them were higher than the R.D.A. (10mg) except 1975. 8. It was found that thiamine and riboflavin were ingested slightly higher than the R.D.A. (1.4mg, vit. $B_1$, 1.6mg, vit. $B_2$). The amount of niacin and ascorbic acid were also higher than the R.D.A. except 15.41mg of niacin in 1975.

• Journal of the Korean Society of Child Welfare
• /
• no.27
• /
• pp.69-93
• /
• 2008

The study tried to identify suicidal factors of adolescences by analyzing effect factors of adolescences' suicide. Demographic factor, Self-respect, depression, suicidal ideation, and school adjustment scale, Social support, self-regulation, and problem solving scale were analyzed as effect factors. 307 junior high and high school students in Pusan city were surveyed by community education experts for this research. As a result, there are significant differences between high suicidal risk group and low suicidal group in all subcategories including economic status. As for the correlation analysis between risk factors and preventive factors, variables, it was analyzed that each variable was correlated to other variables. In addition, multiple regression analysis was conducted to find out affecting factors of adolescence suicide categorized into demographic factor, personal factor, school factor, and social factor. As a result, it was founded that the affecting factors of adolescence suicide were school adjustment, problem solving ability, suicidal ideation, depression and neighborsupport, and self-regulation. That is, to prevent adolescence suicide, the adolescence who are exposed to suicidal risk should be identified by measuring the degree of suicidal ideation, strengthened their school adjustment, and then conducted group therapy to strengthen their problem solving ability and self-regulation. In addition, adolescence suicide can be prevented by strengtheningsocial support for adolescences.

• Journal of Digital Convergence
• /
• v.17 no.3
• /
• pp.139-152
• /
• 2019

In the fourth industrial revolution and the era of convergence and integration, on the situation that the internal colleges are needed active change included in the improvement of educational quality, I tested it on the purpose of empirical analysis with SPSS v.18 how colleges' efforts on the first periodic Organization Evaluation And Accreditation System(OEAAS) affects on the Perceived Management Performances on the perspective of BSC. As the test result, the Degree of Awareness of Colleges' Efforts on the OEAAS affects on just Colleges' Learning and on Growth. The Degree Propriety of Preparation of the OEAAS affects on Customer Performance, on Internal Process Performance, and, on Finance Performance. And the Degree of Satisfaction of Internal Assessment affects on all of BSC 4 performances. The results of this research could be used on making the management idea of colleges' performance on the OEAAS. In the future, it would be needed advanced researches which are able to make relatedness to the expanse of management performance with the OEAAS.

• Journal of Industrial Convergence
• /
• v.17 no.2
• /
• pp.29-34
• /
• 2019

The purpose of this study is to analyze the achievements of employment support by the government support specialization project. The data used in this study are based on the comparison of 5 - year employment support field and the operation results of the program until 2014-2018. The results of the study are as follows. First, the overall employment rate of the university has been continuously increased. Especially, the employment rate of the specialization department has been higher than the employment rate of the non - specialization department. Second, as a result of the analysis of the employment capacity strengthening index and the learning capacity strengthening index, it showed a steady increase in each year and contributed to the cultivation of customized talents required by the local society and the national industry. Third, as a result of analyzing the satisfaction of students who are business users, it was confirmed that the business reflecting the demands of the consumers was realized. Fourth, the continuous improvement of the business and the reflux have made the infrastructure of the employment support project more advanced and the system of supporting employment of the university systematically established. In conclusion, the result of the employment support project according to the specialization program showed excellent results and it is necessary to complement theses results when establishing related business plan in the future.

• The Journal of the Korea Contents Association
• /
• v.22 no.2
• /
• pp.390-399
• /
• 2022

Purpose: This study was conducted to identify the factors affecting nursing students' resilience. Methods: The subjects were 192 nursing students from a college in G city. Data were collected from september 23 to 26, 2019 and analyzed using SPSS 22.0 and descriptive statistics, t-test, ANOVA, Sheffé test, Pearson's correlation coefficients, and multiple regression. Results: Resilience showed a statistically significant difference according to gender, grade, personal relation, motive for application, major satisfaction, grade point in general characteristics. Academic engagement and resilience showed apparent positive correlation (r=.37, p<.001), stress and resilience showed weak negative correlation (r=-.23, p=.001). In multiple regression analysis, the most affecting factor was the academic engagement (𝛽=.24), poor of subjective health status (𝛽=-.21), female (𝛽=-.19), junior of grade (𝛽=.13). These variables explained 33.0% of the total variance in resilience. Conclusion: To strengthen resilience in nursing students, learning atmosphere creation through intrinsic motivation in the regular class. Also, a variable academic engagement program should be provided to be able to positive thinking about academic study and achievement.

• Biomolecules & Therapeutics
• /
• v.31 no.1
• /
• pp.127-138
• /
• 2023

Glycogen synthase kinase-3β (GSK-3β) is an important serine/threonine kinase that implicates in multiple cellular processes and links with the neurodegenerative diseases including Alzheimer's disease (AD). In this study, structure-based virtual screening was performed to search database for compounds targeting GSK-3β from Enamine's screening collection. Of the top-ranked compounds, 7 primary hits underwent a luminescent kinase assay and a cell assay using human neuroblastoma SH-SY5Y cells expressing Tau repeat domain (Tau_RD) with pro-aggregant mutation ΔK280. In the kinase assay for these 7 compounds, residual GSK-3β activities ranged from 36.1% to 90.0% were detected at the IC₅₀ of SB-216763. In the cell assay, only compounds VB-030 and VB-037 reduced Tau aggregation in SH-SY5Y cells expressing ΔK280 Tau_RD-DsRed folding reporter. In SH-SY5Y cells expressing ΔK280 Tau_RD, neither VB-030 nor VB-037 increased expression of GSK-3α Ser21 or GSK-3β Ser9. Among extracellular signal-regulated kinase (ERK), AKT serine/threonine kinase 1 (AKT), mitogen-activated protein kinase 14 (P38) and mitogenactivated protein kinase 8 (JNK) which modulate Tau phosphorylation, VB-037 attenuated active phosphorylation of P38 Thr180/ Tyr182, whereas VB-030 had no effect on the phosphorylation status of ERK, AKT, P38 or JNK. However, both VB-030 and VB-037 reduced endogenous Tau phosphorylation at Ser202, Thr231, Ser396 and Ser404 in neuronally differentiated SH-SY5Y expressing ΔK280 Tau_RD. In addition, VB-030 and VB-037 further improved neuronal survival and/or neurite length and branch in mouse hippocampal primary culture under Tau cytotoxicity. Overall, through inhibiting GSK-3β kinase activity and/or p-P38 (Thr180/Tyr182), both compounds may serve as promising candidates to reduce Tau aggregation/cytotoxicity for AD treatment.

• Journal of the Korean Society of Fisheries and Ocean Technology
• /
• v.20 no.2
• /
• pp.65-71
• /
• 1984

As a primary step in studying the relationship between the arrangement of netting and the section shape of the bag net in the four-seam trawling net, a series of experiments were performed with the simplified model of the bag net made of vinyl film. This model was suspended horizontally in circularly flowing water, with two pairs of suspending threads to four points of symetry at the border of the bag mouth in place of both wing nets. And then, the area distribution of each panel in the bag net was arranged by the portion of the length of the side panel, q to that of the lower or upper panel, p at the border of bag mouth. In the experiments, the section shape of the bag mouth photographed and the tensions on both pairs of suspending threads were measured with two loadcells in circularly flowing water. From the results that the section shape of the bag mouth in circularly flowing water is controlled by the area distribution of panels in the bag net, the author estimated an experimental equation. h/w=k sub(1) e super(k) 2 super(q/p)+C, where h is the central height of the bag mouth, and w is the lateral width of that.