• Journal of Acupuncture Research
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• v.24 no.6
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• pp.37-44
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• 2007

Objectives : The purpose of this study is to find out the effects of Chuna treatment on neck pain caused by traffic accidents. Methods : The 10 patients were divided into 2 groups, with Group A treated with Acupuncture and Chuna, while group B was treated with Acupuncture only. We measured the Visual Analog Scale(VAS), Pain Disability Index(PDI) and Pressure Pain Thresholds before and after treatment in each group. The statistical analysis was performed by using a Mann-Whitney U test and Wilcoxon signed rank test. Results : 1. Group A showed significant improvements in VAS, PDI and Pressure Pain Thresholds(p<0.05). 2. Group B was significantly improved in VAS(p<0.05). However, there was no statistical significance in PDI and Pressure Pain Thresholds(p>0.05). 3. There was no statistical significance between Group A and Group B before and after treatment. Conclusions : These results imply that Chuna treatment with Acupuncture would beeffective and useful on the neck pain caused by traffic accidents.

• Biomolecules & Therapeutics
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• v.20 no.2
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• pp.207-213
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• 2012

The present study examined the effects of krill-derived phosphatidylserine (Krill-PS) on the learning and memory function and the neural activity in rats with trimethyltin (TMT)-induced memory deficits. The rats were administered vehicle (medium-chain triglyceride: MCT) or Krill-PS (50, 100 mg/kg, p.o.) daily for 21 days. The cognitive improving efficacy of Krill-PS in TMT-induced amnesic rats was investigated by assessing the Morris water maze test and by performing choline acetyltransferase (ChAT), acetylcholinesterase (AChE) and cAMP responsive element binding protein (CREB) immunohistochemistry. The rats with TMT injection showed impaired learning and memory of the tasks and treatment with Krill-PS produced a significant improvement of the escape latency to find the platform in the Morris water maze at the $2^{nd}$ and $4^{th}$ day compared to that of the MCT group (p<0.05). In the retention test, the Krill-PS+MCT groups showed increased time spent around the platform compared to that of the MCT group. Consistent with the behavioral data, Krill-PS 50+MCT group significantly alleviated the loss of acetylcholinergic neurons in the hippocampus and medial septum compared to that of the MCT group. Treatment with Krill-PS significantly increased the CREB positive neurons in the hippocampal CA1 area as compared to that of the MCT group. These results suggest that Krill-PS may be useful for improving the cognitive function via regulation of cholinergic marker enzyme activity and neural activity.

• Korean Journal of Acupuncture
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• v.22 no.3
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• pp.105-117
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• 2005

Objective : This study was undertaken to determine if Juglandis Semen herbal acupuncture(Ja) has a protective effect against glycerol-induced acute renal failure in rats. Methods : Rats were dehydrated for 24hr and then injected with 5 ml/kg of 50 % glycerol, one-half of dose in each hindlimb muscle. In experiments for Ja effect, rats received 0.1 ml of Ja extraction in both sides of corresponding $Sh\grave{e}nsh\bar{u}(BL_{23})$ of human body and non-acupuncture points(the root of tail) for 3 days after injection of glycerol. The experimental group were divided into the Normal group, the Control group, the Ja to $Sh\grave{e}nsh\bar{u}(BL_{23})$ group(Ja-AS), the Ja to non-acupuncture points group(Ja-AN). Results : There were significant decrease of urine volume, BUN, fractional glucose excretion, fractional phosphate excretion, total protein level in Ja-AS as compared with the control group. Conclusion : This suggests that Ja-AS could be used in prevention and treatment of acute renal failure. However, the precise mechanisms of Ja protection remain to be determined.

• Journal of Acupuncture Research
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• v.33 no.2
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• pp.181-187
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• 2016

Objectives : The purpose of this report is to introduce a case of osteochondral lesions of the left talus caused by ankle sprain and suggest complex traditional Korean medical care with warm needling therapy as a possible method of conservative treatment. Methods : A 20-year-old male with osteochondral lesions of the left talus complaining of ankle pain and restricted range of movement was treated mainly with warm needling therapy and other combined Korean medicine therapy from January 5, 2015 to January 12, 2015. Improvements of symptoms were measured by American Orthopaedic Foot & Ankle Society Score (AOFAS Score), Visual Analog Scale (VAS) and Range of movement (ROM). Results : During 8 days of treatment, the patient showed gradual improvement in AOFAS score, VAS at rest and at weight bearing position, as well as ROM of the ankle. Conclusion : According to the result, warm needling therapy is a possible conservative treatment for osteochondral lesions of the talus. Further studies are needed regarding possible longterm effects.

• The Journal of Internal Korean Medicine
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• v.28 no.3
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• pp.632-644
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• 2007

Objectives : Although dysphagia is a common complication in stroke patients, there are few studies or reports about its treatment in oriental medicine. This study was to report the effects of scalp-acupuncture and electro-acupuncture in stroke patients with dysphagia. Methods : Three stroke patients with dysphagia hospitalized in our hospital were treated by scalp-acupuncture and electro-acupuncture simultaneously every day, 5 times a week for 4 weeks. Results : All of them showed constant improvement during the four weeks. Not only did their objective measures improve, but also their subjective symptoms such as throat discomfort, sputum, swallowing disturbance etc. Conclusions : This suggests that scalp-acupuncture and electro-acupuncture are quite effective when treating stroke patients with dysphagia. More clinical data and studies are to be done for efficient application.

• Journal of Acupuncture Research
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• v.18 no.5
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• pp.70-76
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• 2001

Objective : In order to study effects of decreasement of blood pressure on hypertension patients by moxibustion a clinical study was performed. Methods : Moxibustion at Quchi(LI11), Guanyan(CV4) 10 times on 25 hyper tension patients who were treated via opd on Dong-Eui Oriental Medical Hospital. Results : 1. After 10 times moxibustion at Quchi(LI11), Guanyan(CV4),the systolic blood pressure were decreased 16.5% degree. 2. After 10 times moxibustion at Quchi(LI11), Guanyan(CV4),the diastolic blood pressure were decresed 26.6% degree. 3. Subjective symptoms(i.e. headache, dizziness, heat in the upper part of the body, dyspnea etc) were decresed after 10 times moxibustion at Quchi(LI11), Guanyan(CV4). Conclusion : Continous Moxibustion at Quchi(LI11), Guanyan(CV4) implies decreasement of blood pressure and improvement of subjective symptoms.

• Journal of Acupuncture Research
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• v.18 no.3
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• pp.114-122
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• 2001

Objective : The present study was carried out to determine if Juglandis Semen Aquacupuncture(JSA) exerts beneficial effect against the urine concentrating defect induced by glycerol injection in rabbits. Methods : In order to test the effect of JSA, rabbits were acupunctured with $0.5m{\ell}$ of 1%JSA for 7days at both sides of $Sh{\grave{e}}ns{\bar{u}}$(BL23) before the glycerol injection. The other animals were pretreated with an equal volume of saline instead of JSA. Results : The urine flow was reduced, but the urine osmolality was significantly lower than the basal period in glycerol-injected animals, indicating that glycerol causes the urine concentrating defect. The fractional excretion of Na and K was increased in glycerol-treated animals. The Free-water clearance and fractional water excretion(V/GFR) were increased in animals treated with glycerol. Conclusion : These results indicate that glycerol injection resulted an impairment in the urine concentrating ability in rabbits. Such changes were prevented by JSA. JSA may be used as a method to treat and prevent glycerol-induced acute renal failure.

• Journal of Acupuncture Research
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• v.18 no.3
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• pp.123-133
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• 2001

Objective : This study was undertaken to determine whether Cordyceps sinensis Sacc. (CSS) extract exerts the protective effect against oxidant-induced alterations in membrane transport function in renal tubules. Methods : Membrane transport fucntion was estimated by examining alterations in p-aminohippurate (PAH) uptake in rabbit renal cortical slices. For induction oxidative stress, slices were treated with an organic peroxide cumene hydroperoxide for 60 min at $37^{\circ}C$. Cumene hydroperoxide inhibited PAH uptake in a time dependent manner. Results : CSS at 0.5-5% concentrations prevented cumene hydroperoxide-induced inhibition of PAH uptake. CSS at 1% also attenuated LDH release and lipid peroxidation induced by cumene hydroperoxide. When slices were treated with 0.2 mM mercury chloride, PAH uptake was inhibited and lipid peroxidation was increased. These changes by mercury were significantly prevented by CSS. Conclusion : These results suggest that CSS prevents oxidant-induced alterations in membrane transport function in rabbit renal cortical slices. Such protective effect of CSS may be attributed to inhibition of peroxidation of membrane lipid.

• Journal of Pharmacopuncture
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• v.5 no.1 s.8
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• pp.171-180
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• 2002

Objective: The purpose of this study is to develop and activate the methods of using the arsenic compounds as the anti-cancer medicine. Methods: We investigated some literatures on the using methods, the effects for anti-cancer, and the toxicity of the arsenic compounds. Results: The results are summarized as follows. 1. As is the one of the nitrogen familIy(5A familly). 2. The Arsenic compounds which have been used as the one of the oriental medicine are the Arsenicum Sulbimatum($As_2O_3$) and the Realgar(AsS). 3. As+ 3 is more toxic than the other arsenic compounds. The fatal amount is 100-300 mg. So, it is used 1-5 mg/day as a medicine. 4. The Arsenicwn Sulbimatum($As_2O_3$) and the Realgar(AsS) are used after the heat treatment or the boiling with the acetic acid. 5. The gastrointestinal tract, vessel, and respiration are affected by the acute toxicity of the arsenic compounds. 6. The arsenic compounds are good for the dermatosis and the malignant cancer, especially the acute promyelocytic leukcrnia(APL). we should study the reason of these and the different effect in concentration, also develop new methods of using the the arsenic compounds as getting rid of their toxicity.

• Journal of Haehwa Medicine
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• v.22 no.2
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• pp.155-162
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• 2014

Objective : The purpose of this study was to investigate the effects of acupuncture treatment on frequently adopted acupuncture point and self exercise therapy for lumbar sprain patient Methods : For this study, a retrospective chart review was conducted. Data are derived from lumbar sprain patients who have received hospital treatment in Daejeon Univ. Cheon-Ahn Korean Hospital. All patients were treated with acupuncture treatment on high frequency acupuncture point (BL25, BL23, BL24, GB30, BL40, BL26, BL60, GB34), physical therapy and herbal medicine and self exercise therapy(Swiss ball exercise, Lumbar stabilization exercise.) We measured visual analogue scale(VAS), Oswestry disability index(ODI), Pain threshold twice(pre-treatment and post-treatment) on 1st day and 5 days later. Results : After being treated, lumbar sprain patients were meaningful improved in VAS, ODI, pain threshold The VAS score, ODI score were statistically decreased after treatment and the pain threshold was statistically increased after treatment. Conclusion : In this study, treatment on frequently adopted acupuncture point and self exercise therapy were effective on lumbar sprain patient.