• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2007.06a
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• pp.129-130
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• 2007

3,3-Dimethyl-1-butene ($C_6H_{12}$) monomer를 이용하여 RF power와 압력에 따라 막을 증착하였다. Power/pressure (W/Torr)가 증가할수록 증착된 비정질 탄소막은 FT-IR 스펙트럼에서 $CH_x$ (at around $2900cm^{-1}$)는 감소하였지 만 elastic modulus는 증가하는 것으로 나타났다.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2007.06a
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• pp.185-186
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• 2007

3,3-Dimethyl-1-butene ($C_6H_{12}$) monomer를 이용하여 RF power와 압력에 따라 막을 증착하였다. 증착된 막은 power/pressure (W/Torr)가 증가할수록 비정질 탄소막은 FT-IR 스펙트럼에서 $CH_x$ (at around $2900cm^{-1}$)는 감소하였고, n과 k값은 증가하는 것으로 나타났다.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2007.06a
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• pp.104-105
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• 2007

3,3-Dimethyl-1-butene($C_6H_{12}$) monomer를 이용하여 RF power와 압력에 따라 증착된 막의 refractive index와 extinction coefficient를 알아보았다. 증착된 막의 n & k는 power/pressure가 증가할수록 증가하였으며, Ar으로 증착된 막이 더 낮은 값을 갖는 것으로 나타났다.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2007.06a
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• pp.160-161
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• 2007

3,3-Dimethyl-1-butene ($C_6H_{12}$) monomer를 이용하여 RF power와 압력에 따라 막을 증착하였다. 증착된 막은 power/pressure (W/Torr)가 증가할수록 비정질 탄소막은 Raman 스펙트럼에서 D peak가 증가하였고, ring 구조의 막을 형성하였다. 또한 ring 구조의 막이 형성됨으로써 hardness와 modulus는 각각 12 GPa과 85 GPa로 선형적으로 증가하는 것으로 나타났다.

• The Journal of Korean Medicine
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• v.28 no.1 s.69
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• pp.224-236
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• 2007

Background : Chunghyul-dan is a combinatorial herbal medicine; previous studies reported it had therapeutic effects for microangiopathy, a major part in the progression of small vessel disease, as well as having anti-hypertensive, anti-hyperlipidemic, anti-apoptotic, anti-oxidative, and anti-inflammatory activities. Therefor, we examined the inhibitory effect of Chunghyul-dan on stroke recurrence in patients with small vessel disease. Methods : We prescribed Chunghyul-dan at 600 mg a day to patients with small vessel disease, and monitored stroke recurrence, drug compliances, and adverse effect for 1 year. We then performed follow-up brain MRI to find new vascular lesions after 1 year of Chunghyul-dan medication. For the subjects lost to follow-up, we assessed their prognosis after 1 year by telephone. Results : There were 73 subjects treated with Chunghyul-dan for 1 year; new vascular events were found in 3. Of the 85 subjects lost to follow-up, fifty four could be contacted, and eight of them had stroke recurrence. One year of Chunghyul-dan medication reduced the odds ratio of stroke recurrence by 75% compared to the subjects lost to follow-up and the rate increased to 88%, when adjusted for other relevant risk factors for stroke recurrence. These reductions were much higher than those of aspirin and other kinds of conventional anti-platelets. There was no adverse effect in any of the study subjects. Conclusions : We suggest Chunghyul-dan could be useful for inhibition of stroke recurrence. Further study with a randomized controlled trial is needed to confirm this suggestion.

• Korean Journal of Pharmacognosy
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• v.39 no.3
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• pp.203-207
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• 2008

Man Kyung Dan(萬經丹) is a Chinese patent medicine which has been used for rheumatic neuralgia, apoplexy, extremitas neurolepsis in Korea. It consists of 16 kinds of powdered crude drugs. In powered crude drugs, it is hard to identify each component by chemical analysis or morphological examination. However, the method of identification of powdered crude drugs has not been clearly established. For the identification of individual crude drugs in such powdery mixtures, microscopic method may advantageously be used, as it requires only small amount of specimens. In this study, it is demonstrated that the microscopic method is very effective for the identification of 16 crude drug ingredients in Man kyung Dan.

• Journal of Korean Medical classics
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• v.24 no.5
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• pp.131-145
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• 2011

I had come at the conclusion of the development history of Disease Bi(痞病) reflected in Yi Cheon (李梴)'s work, "Euhakibmun(醫學入門)" in the respects of the causes, mechanism, symptoms, differential diagnosis and treatments. The causes of Disease Bi(痞病) mentioned at "Euhakibmun(醫學入門)" followed the Ju Dan-Gyeo(朱丹溪)'s theory. The mechanism of it went after the viewpoints of "Nae-Gyeong(內經)", Jang Jung-Gyeong(張仲景), Yi Dong-Won(李東垣) and Wang Ho-Go(王好古). The symptoms of it kept the Ju Dan-Gyeo(朱丹溪)'s theory. Yi Cheon distinguished Disease Bi(痞病) from Gyeol-Hyung(結胸) according to Jang Jung-Gyeong's theory. He knew it from abdominal dropsy(脹滿) according to Ju Dan-Gyeo's theory. He also divided it into two respects of deficiency(虛) and excessive(實) from Yi Dong-Won's viewpoint. Jang Jung-Gyeong first suggested that treatments of it could be selected according to the difference of deficiency, excessive(實), cold(寒), hot(熱), sputum(痰), fluid(飮), blood(血) and food(食). Yi Dong-Won insisted many doctors could make a mistake because they only used herbs for Gi(氣藥) instead of herbs for blood(血藥) together. Wang Ho-Go(王好古) maintained his opinion that treatments of both digestion(消導) and assistance(補益), remedies of bitter and hot herbs can recover patients from Disease Bi(痞病). Yi Cheon followed their theories properly.

• The Journal of Internal Korean Medicine
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• v.43 no.2
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• pp.311-319
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• 2022

Objective: This case report describes an 82-year-old man complaining of insomnia with pain after discontinuation of quetiapine. Methods: The patient was treated with the herbal extraction Gilchogeun-dan, and symptomatic improvement was assessed using the Korean version of the Pittsburgh Sleep Quality Index. Results: Following 28 days of Gilchogeun-dan treatment, the patient's symptoms improved. Conclusions: This case suggests that Gilchogeun-dan could be effective in treating insomnia with pain through central nervous depressant activity and analgesic effect.

• The Journal of Korean Medical History
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• v.14 no.2
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• pp.189-248
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• 2001

In this essay, following final conclusions have been drawn by analyzing medical ideology and research system of Yi cheon in Yi hak yip mun("醫學入門"). Firstly, even though the existing medical history researchers are not noting the system of Yi-cheon's medical ideology, this essay has proved the man as a doctor who succeeded the (main system) based on the content of Yi-hak-yip-mun("醫學入門") by Ju-Dan-Gae(朱丹溪). The outline of this proof is as follows. 1. Those doctors who had actively researched in Myung era(明代), were basically taking over the medical studies and result of Gum-Won era(金元代). However, depending on whose theory is to be followed, the followers are largely divided into two groups of Ju-Dan-Gae Academics(丹溪學派) and On-Boe Academics(溫補學派). In addition, both Ju-Dan-Gae Academics(丹溪學派) and On-Boe Academics(溫補學派) hold contradictory ideologies to that of the main medical system. In Yi-hak-yip-mun("醫學入門"), Yi-cheon(李?) ties The Text of Whang-Jae-Nae-Kyung("黃帝內經"), Jang-Jung-Kyung(張仲景), Yu-Ha-Gun(劉河間), Yi-Dong-Won(李東垣), Ju-Dan-Gae(朱丹溪) into one pedigree. With regard to the main system, he especially marks Ju-Dan-Gae(朱丹溪) for his efforts in gathering various medical theories into a large compilement. 2. When Yi-Cheon(李?) was writing Yi-Hak-Yip-Mun("醫學入門"), he made references to various medical publishings, among those book which he had utilized, books by Ju-Dan-Gae Academics(丹溪學派) had affected him more than anything else in terms of both quality and quantity. 3. Yi-Cheon(李?)'s "Congested Phlegm Theory(痰鬱論)" had succeeded "Congested Phlegm Theory(痰鬱論) of Ju-Dan-Gae Academics(丹溪學派). His Yi-Hak-Yip-Mun("醫學入門"), carries a more complete form of "Congested Phlegm Theroy(痰鬱論) which was made into a more systemic and widely applicable method which was by Ju-Dan-Gae Academics(丹溪學派). Secondly, Yi-Hak-Yip-Mun("醫學入門"), is a medical book which was written in the process of systemic reorganization of medical theories of various academic parties in Myung 명 era. Since this process was hearing its completion in the period of Yi-Cheon(李?), he chose specific ways of reshuffling, whilst seeking ways to efficiently utilizing existing medical information . He provided a standard to specific ways. He rearranged the existing medical theories based upon these standards. He also contributed to clinical medicine by providing description of symptoms focused upon the symptoms differentiated In Conclusion, Yi-Hak-Yip-Mun("醫學入門") holds systematic medical information which was developed by Ju-Dan-Gae Academics(丹溪學派). Also, Yi-Cheon(李?) uniformly classified the clinical experiences of existing Ju-Dan-Gae Academics(丹溪學派). He had contributed in the clinical use of Ju-Dan-Gae Academic(丹溪學派)'s clinical experience by providing main points from differentiation of symptoms.

• The Journal of Korean Medicine
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• v.26 no.2 s.62
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• pp.77-84
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• 2005

Objectives: Chunghyul-dan is a combinatorial herbal medicine, and previous studies reported it had therapeutic effects for microangiopathy, which is a major part. in the progression of stroke, as well as having anti-hypertensive, anti-hyperlipidemic, anti-apoptotic, anti-oxidative, and anti-inflammatory activities, Therefore, we examined the inhibitory effect of Chunghyul-dan on stroke occurrence in patients with silent brain infarction. Methods: We prescribed Chunghyul-dan at 600 mg a day to patients with silent brain infarction confirmed by brain MRI, and monitored stroke occurrence, drug compliances, and adverse effects for 1 year, We then performed follow-up brain MRI to detect new vascular lesions after 1 year of Chunghyul-dan medication. As for the subjects lost to follow-up, we assessed their prognosis after 1 year by telephone. Results: There were twenty-one subjects who were treated with Chunghyul-dan for more than 1 year, None of them experienced new clinical syndromes characterized by rapidly developing clinical symptoms and signs of focal and at times global loss of brain function, which could be accompanied with evidence of stroke occurrence, or any adverse effects during the Chunghyul-dan medication period. These results might be explained by various biochemical effects of Chunghyul-dan on microangiopathy, which is closely related with cell cycle progression, hypertension, hyperlipidemia, vascular inflammation, and oxidative damage. Of the 10 subjects lost to follow-up, six were reached; two of them had stroke occurrence. Conclusions: We suggest Chunghyul-dan could be useful for prevention of stroke occurrence in patients with silent brain infarction by preventing the progression of microangiopathy. Further study with a randomized controlled trial is needed to confirm this suggestion.