• JSTS:Journal of Semiconductor Technology and Science
• /
• v.13 no.1
• /
• pp.79-86
• /
• 2013

We describe a neural stimulator front-end with arbitrary stimulation waveform generator and adaptive supply regulator (ASR) for visual prosthesis. Each pixel circuit generates arbitrary current waveform with 5 bit programmable amplitude. The ASR provides the internal supply voltage regulated to the minimum required voltage for stimulation. The prototype is implemented in $0.35{\mu}m$ CMOS with HV option and occupies $2.94mm^2$ including I/Os.

• Genomics & Informatics
• /
• v.4 no.3
• /
• pp.125-128
• /
• 2006

We present an openfree hypertext (also known as wiki) web cluster called BioCC. BioCC is a novel wiki farm that lets researchers create hundreds of biological web sites. The web sites form an organic information network. The contents of all the sites on the BioCC wiki farm are modifiable by anonymous as well as registered users. This enables biologists with diverse backgrounds to form their own Internet bio-communities. Each community can have custom-made layouts for information, discussion, and knowledge exchange. BioCC aims to form an ever-expanding network of openfree biological knowledge databases used and maintained by biological experts, students, and general users. The philosophy behind BioCC is that the formation of biological knowledge is best achieved by open-minded individuals freely exchanging information. In the near future, the amount of genomic information will have flooded society. BioGG can be an effective and quickly updated knowledge database system. BioCC uses an opensource wiki system called Mediawiki. However, for easier editing, a modified version of Mediawiki, called Biowiki, has been applied. Unlike Mediawiki, Biowiki uses a WYSIWYG (What You See Is What You Get) text editor. BioCC is under a share-alike license called BioLicense (http://biolicense.org). The BioCC top level site is found at http://bio.cc/

• Journal of Ginseng Research
• /
• v.36 no.1
• /
• pp.27-39
• /
• 2012

Panax ginseng exhibits pleiotropic beneficial effects on cardiovascular system, central nervous system, and immune system. In the last decade, numerous preclinical findings suggest ginseng as a promising therapeutic agent for diabetes prevention and treatment. The mechanism of ginseng and its active components is complex and is demonstrated to either modulate insulin production/secretion, glucose metabolism and uptake, or inflammatory pathway in both insulin-dependent and insulin-independent manners. However, human studies are remained obscure because of contradictory results. While more studies are warranted to further understand these contradictions, ginseng holds promise as a therapeutic agent for diabetes prevention and treatment. This review summarizes the evidences for the therapeutic potential of ginseng and ginsenosides from in vitro studies, animal studies and human clinical trials with a focus on diverse molecular targets including an AMP-activated protein kinase signaling pathway.

• Journal of Society of Preventive Korean Medicine
• /
• v.12 no.2
• /
• pp.115-130
• /
• 2008

It is very important problem that exactly distinguish constitution, in Sasang constitutional Medicine. But, it is careless that discuss the propriety of 'Sasang constitution unchangeability theory(四象體質 不變論)'. The foundation of Sasang constitution unchangeability theory is the sentence in DongUi SuSae BoWon Sa-dan theory(東醫壽世保元 四端論) : "The Organ system of Taeyang(太陽), Taeum(太陰), Soyang (少陽) and Soeum(少陰) is the variation of YinYang(陰陽), is firm nature and is unnecessary agreement. (太少陰陽之臟局 陰陽之變化也 天稟之已定 固無可論)". But, the foundation of Sasang constitution unchangeability theory contradict the theory that Organ system(臟腑) is made by deviation of emotions(joy, anger, sorrow and pleasure :喜怒哀樂) or temperament(性情). Because these emotions is revealed after birth(後天), the deviation of Organs system made by deviation of emotions is not innate, is acquired after birth. Therefore, it is necessary to discuss the opinion that Sasang constitution is variable after birth. The conclusion of our study is that Sasang constitution can be variable after birth.

• Journal of Korean Physical Therapy Science
• /
• v.18 no.1
• /
• pp.79-84
• /
• 2011

Background: The purpose of this study was to investigate differences in balancing ability and weight bearing between paretic and non-paretic. Methods: Subjects of the study were consisted of 30 acute hemiplegia patients(paretic 15, non-paretic 15) who were receiving rehabilitation therapy in hospital. Weight shifting was quantitatively evaluated to determine the ability of patients to and during conscious weight shifting on the Gaitview. Independent t-test was utilized to detect the mean difference between the groups. Results: 15 patients with stroke were able to shift more weight onto the paretic leg. And pressure ratio of right hemiplegia was significantly difference on the nonparetic leg, pressure ratio of left hemiplegia was significantly difference onto the paretic leg. Conclusions: Patients with left hemiplegia who was cortical lesions in the right hemisphere were able to shift more body weight onto their paretic leg. These patients should be encouraged to practice shifting their weight towards their non-paretic leg to improve their balance.

• Journal of Microbiology and Biotechnology
• /
• v.31 no.10
• /
• pp.1366-1372
• /
• 2021

Bacterial nanocellulose (BNC) is a biocompatible material with a lot of potential. To make BNC commercially feasible, improvements in its production and surface qualities must be made. Here, we investigated the in situ fermentation and generation of BNC by addition of different cellulosic substrates such as Avicel and carboxymethylcellulose (CMC) and using Komagataeibacter sp. SFCB22-18. The addition of cellulosic substrates improved BNC production by a maximum of about 5 times and slightly modified its structural properties. The morphological and structural properties of BNC were investigated by using Fourier transform-infrared spectroscopy (FT-IR), scanning electron microscopy and X-ray diffraction. Furthermore, a type-A cellulose-binding protein derived from Clostridium thermocellum, CtCBD3, was used in a novel biological analytic approach to measure the surface crystallinity of the BNC. Because Avicel and CMC may adhere to microfibrils during BNC synthesis or crystallization, cellulose-binding protein could be a useful tool for identifying the crystalline properties of BNC with high sensitivity.

• Journal of the Korean Institute of Telematics and Electronics
• /
• v.23 no.6
• /
• pp.950-956
• /
• 1986

In this paper, a direct addressing mode of a microprocessor is introduced to save memory capacity, and also a dedicated digital filter is constructed to speed up the filter processing and to enable an easy selection of the impulse response types. A theoretical analysis has been conducted on the errors caused by the finite word klength, rounding-off and multiplication procedures. The digital filter designed by the proposed method is made into a module which can function as a 7th-order recursive or a 14-order nonrecursive type with a simples witch operation. The proposed filter is implemented on a printed-circuit board. The frequency characteristics of this filter can be controlled by the multiplication values stored in ROMs. A low-pass, a high-pass and a band-pass filter have been designed and their frequency characteristics are verified by actual measurements. For a order higher filer, two filter modules have been cascaded into an integrated filter of 23rd-order non-recursive low-pass type and a 12th-order recursive multiband type. Their frequency characteirstics have been found to agree with the theory.

• Composites Research
• /
• v.20 no.6
• /
• pp.15-20
• /
• 2007

In this work, the structural response of thin-walled, composite beams with built-in twist angles is analyzed using a mixed beam approach. The analytical model includes the effects of elastic couplings, shell wall thickness, and torsion warping. Reissner's semi-complimentary energy functional is used to describe the beam theory and also to deal with the mixed-nature in the beam kinematics. The bending and torsion related warpings introduced by the non-zero pretwist angles are derived in closed-form through the proposed beam formulation. The theory is validated with available literature and detailed finite element analysis results for rectangular solid section beams with elastic couplings. Very good correlation has been obtained for the cases considered.

• Proceedings of the Plant Resources Society of Korea Conference
• /
• 2020.08a
• /
• pp.74-74
• /
• 2020

Skin is continuously exposed to a variety of environmental stresses, including ultraviolet (UV) radiation. UVB is an inherent component of sunlight that crosses the epidermis and reaches the upper dermis, leading to increased oxidative stress, activation of inflammatory response and accumulation of DNA damage among other effects. In the present study, the anti-wrinkle mechanism of Acorus gramineus callus culture supernatant (GB-AGS-PSC) was elucidated in UVB treated HaCaT keratinocytes. GB-AGS-PSC prevented the matrix metalloprotease 1 (MMP-1), elastin, and pro-collagen product and cytotoxicity and SOD inhibition. Quantitative polymerase chain reaction showed that GB-AGS-PSC-treated cells displayed dose-dependent increase in messenger RNA expression levels of Aquaporin 3 (AQP3), Keratin 1(KRT1), fillagrin, and hyaluronan synthase-2 (HAS 2) and decreased expression levels of matrix metalloproteinase-3, -9, and -13 in UVB treated HaCaT keratinocytes. Additionally, GB-AGS-PSC suppressed TNF-α, IL-1β, and IL-8 product for inflammatory responses in UVB treated HaCaT keratinocytes. Therefore, GB-AGS-PSC may be useful as an anti-photoaging resource for the skin.

• Proceedings of the Korea Information Processing Society Conference
• /
• 2023.11a
• /
• pp.894-895
• /
• 2023

증강현실(AR)이란, 현실의 이미지나 배경에 3차원 가상 이미지를 입혀 실시간으로 출력되는 컴퓨터 그래픽 기법이다. 본 논문에서는 AR 서비스를 이용한 여행 기록 애플리케이션을 제안한다. 현재 제공되는 서비스에서는 장소에 대해 제공하는 정보가 매우 한정적이다. 따라서 공유 커뮤니티를 형성할 수 있도록 하여 다양한 정보를 전달하고 직접적인 시각 자료를 제공받을 수 있는 애플리케이션이 필요하다고 생각하여 기획하게 되었다. ReactNative와 SpringBoot를 사용하며, MySQL을 이용하여 데이터를 저장한다. Google Map API를 활용하여 사용자가 기록하고자 하는 장소에 대한 위도와 경도 정보를 받을 수 있도록 하며, AR 기능은 Unity로 구현하였다. AR을 포함한 혼합 현실 서비스를 제공하여 사용자들이 본인의 경험에만 의존하는 것이 아닌 풍부한 몰입력과 현장감을 통해 보다 가시적이고 생생한 다이어리 기록을 만들 수 있다.