• Title/Summary/Keyword: Jumping

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In vivo Antitumor Activity and Acute, Subacute Toxicity of Keumsa (Phellinus linteus) Extracts (금사목질진흙버섯 자실체 추출물의 in vivo 항암활성 및 급성, 아 급성 독성 시험)

  • Kim, Jong-Myeung;Park, Jun-Duck;Park, Dong-Chan;Kim, Byung-Oh
    • Journal of Life Science
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    • v.23 no.11
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    • pp.1388-1396
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    • 2013
  • This study used an S-180 cell-injected mouse model to evaluate the antitumor effects of the acute and subacute toxicity of Keumsa (Phellinus linteus) extract intravenously administrated in ICR mice. When administered intravenously (31.3-250 mg/kg body weight), Keumsa (Phellinus linteus) extract significantly inhibited the growth of the solid tumor cell. The antitumor activity of Keumsa (Phellinus linteus) extract increased in a dose-dependent manner. The highest dose (250 mg/kg body weight) was highly effective, reducing tumor formation by 42.7% compared with the control group. In the acute toxicity test, $LD_{50}$ of the Keumsa (Phellinus linteus) extract showed 632.84 mg/kg (♂) and 814.48 mg/kg (♀) after intravenous administration. In addition, liver and spleen weight were increased in a dose-dependent manner. In the subacute toxicity test, the mice were intravenously administered over the course of 28 days. The $LD_{50}$ of the Keumsa (Phellinus linteus) extract showed 355.41 mg/kg (♂) and 383.53 mg/kg (♀) after intravenous administration. The liver and spleen weight also increased in a dose-dependent manner. In the case of the group that received more than 125 mg/kg of intravenous administration, exercise capacity, such as jumping ability and agility, were significantly increased. These results suggest that Keumsa (Phellinus linteus) extract can be regarded as a potent enhancer of the innate immune response, and it can be considered as a new natural product with low toxicity that may be used as a candidate for antitumor action.

A Study on the Government's Support Policy of SMEs (국내 중소기업의 정부지원정책에 관한 연구)

  • Chung, Young-Woo;Kim, Pan-Jin
    • Journal of Distribution Science
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    • v.8 no.2
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    • pp.33-44
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    • 2010
  • This paper is to give Korean small and medium enterprises the direction for strengthening the competitiveness through looking the problems and improvements about the government policy that domestic small and medium enterprises is essential for the growth anc development. To derive these results, the theoretical background was established through considering the existing research literature. This paper has drawn the final policy alternatives through collecting field data and analysing the practical support after meeting with executives that are operating a small business related to research purposes. In this paper in order to strengthen the competitiveness of small and medium enterprises of the government's support policy, it is critical for the financial support policy and the tax support policiest policy. The conclusions in this study are following. SMEs in Korean economic growth contribute greatly to advance industrial structure, regional balanced development, employment opportunities and to alleviate the concentration of economic power. However, there are these positive, and the negative such as the absence of entrepreneurial spirit and passive participation in society. Therefore, SMEs now should have your own a lot of effort to improve their competitiveness. In addition, government believe that SMEs directly impact on the national economy, especially the people, but they still need systematic and aggressive policy support in the future because of the lack of the result. Finally, if they try strategic approach for several issues and improvement of government's support policy that this study suggested for SMEs, the entrance toward developed countries can be through jumping of Korean economy.

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Effects of Kimchi Supplementation and/or Exercise Training on Body Composition and Plasma Lipids in Obese Middle School Girls (운동 및 김치 보충제 섭취가 비만 여중생의 신체조성 및 혈중지질에 미치는 영향)

  • 백영호;곽정록;김세종;한성섭;송영옥
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.30 no.5
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    • pp.906-912
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    • 2001
  • The effects of aerobic exercises and/or supplementation of kimchi on changes of the body composition and plasma lipids of obese middle school girls were studied. Thirty eight girls, 28 obese girls and 10 normal weighed girls, were paricipated. Among obese girls, 8 were assigned to exercise group (FG) 12 were grouped as kimchi group (KG) , and 8 were asked to practice excercise and to take kimchi simultaneously(excercise kimchi group, EKG). Ten girls whose weight is normal asked to remain o their own diet during 6 weeks of experiment (control group, CG)/ EG practiced jogging and rope-jumping for 60 minutes four times a week and KG took 3 g of freeze-dried kimchi packed in a 500 mg capsule daily which is equivalent to 30 g of fresh kimchi, EKC, EG and KG showed beneficial effects on changes of the body composition and plasma lipids compared to those of CG, EG showed greater effect than KG in reducing body fat resulted decrease in BMI, fat mas,. abdominal fat, and triglyceride concentration and increase in HDL-cholesterol. KG seemed to have greater effect on lowering plasma cholesterol and LDL-cholesterol than EG/ But the greatest effects in terms of reduction in weight, BMI fat mass, abdominal fat, total cholesterol, LDL-cholesterol, triglyceride, and increase in HDL-cholesterol were observed from EKG. These results indicate that kimchi supplemenation while practicing excercise might improve the obese state by reducing body fat content as well as reducing plasma lipids.

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Molecular Theory of Plastic Deformation (Ⅲ)$^*$

  • Kim, Jae-Hyun;Ree, Tai-Kyue;Kim, Chang-Hong
    • Bulletin of the Korean Chemical Society
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    • v.2 no.3
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    • pp.96-104
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    • 1981
  • (1) The flow data of f (stress) and ${\dot{s}$ (strain rate) for Fe and Ti alloys were plotted in the form of f vs. -ln ${\dot{s}$ by using the literature values. (2) The plot showed two distinct patterns A and B; Pattern A is a straight line with a negative slope, and Pattern B is a curve of concave upward. (3) According to Kim and Ree's generalized theory of plastic deformation, pattern A & B belong to Case 1 and 2, respectively; in Case 1, only one kind of flow units acts in the deformation, and in Case 2, two kinds flow units act, and stress is expressed by $f={X_1f_1}+{X_2f_2}$where $f_1\;and\;f_2$ are the stresses acting on the flow units of kind 1 and 2, respectively, and $X_1,\;X_2$ are the fractions of the surface area occupied by the two kinds of flow units; $f_j=(1/{\alpha}_j) sinh^{-1}\;{\beta}_j{{\dot{s}}\;(j=1\;or\;2)$, where $1/{\alpha}_j\;and\;{\beta}_j$ are proportional to the shear modulus and relaxation time, respectively. (4) We found that grain-boundary flow units only act in the deformation of Fe and Ti alloys whereas dislocation flow units do not show any appreciable contribution. (5) The deformations of Fe and Ti alloys belong generally to pattern A (Case 1) and B (Case 2), respectively. (6) By applying the equations, f=$(1/{\alpha}_{g1}) sinh^-1({\beta}_{g1}{\dot{s}}$) and $f=(X_{g1}/{\alpha}_{g1})sinh^{-1}({\beta}_{g1}{\dot{s}})+ (X_{g2}/{\alpha}_{g2})\;shih^{-1}({\beta}_{g2}{\dot{s}})$ to the flow data of Fe and Ti alloys, the parametric values of $x_{gj}/{\alpha}_{gj}\;and\;{\beta}_{gs}(j=1\;or\;2)$ were determined, here the subscript g signifies a grain-boundary flow unit. (7) From the values of ($({\beta}_gj)^{-1}$) at different temperatures, the activation enthalpy ${\Delta}H_{gj}^{\neq}$ of deformation due to flow unit gj was determined, ($({\beta}_gj)^{-1}$) being proportional to , the jumping frequency (the rate constant) of flow unit gj. The ${\Delta}H_{gj}\;^{\neq}$ agreed very well with ${\Delta}H_{gj}\;^{\neq}$ (self-diff) of the element j whose diffusion in the sample is a critical step for the deformation as proposed by Kim-Ree's theory (Refer to Tables 3 and 4). (8) The fact, ${\Delta}H_{gj}\;^{\neq}={\Delta}H_{j}\;^{\neq}$ (self-diff), justifies the Kim-Ree theory and their method for determining activation enthalpies for deformation. (9) A linear relation between ${\beta}^{-1}$ and carbon content [C] in hot-rolled steel was observed, i.e., In ${\beta}^{-1}$ = -50.2 [C] - 40.3. This equation explains very well the experimental facts observed with regard to the deformation of hot-rolled steel..

Biomechanical Analysis of Walking and Running after a Surgically Repaired Achilles Tendon Rupture (아킬레스건 파열 수술 후 걷기 및 달리기 운동역학적 분석)

  • Heo, Jeong;Park, Sang-Kyoon
    • Korean Journal of Applied Biomechanics
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    • v.31 no.4
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    • pp.241-248
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    • 2021
  • Objective: The purpose of this study was to investigate the difference in muscle strength, kinematics, and kinetics between injured and non-injured sides of the leg after Achilles Tendon Rupture surgery during walking and running. Method: The subjects (n=11; age = 30.63 ± 5.69 yrs; height = 172.00 ± 4.47 cm; mass = 77.00 ± 11.34 kg; time lapse from surgery = 29.81 ± 10.27 months) who experienced Achilles Tendon Rupture (ATR) surgery participated in this study. The walking and running trials were collected using infrared cameras (Oqus 300, Qualisys, Sweden, 100 Hz) on instrumented treadmill (Bertec, U.S.A., 1,000 Hz) and analyzed by using QTM (Qualisys Track Manager Ver. 2.15; Qualisys, U.S.A). The measured data were processed using Visual 3D (C-motion Inc., U.S.A.). The cutoff frequencies were set as 6 Hz and 12 Hz for walking and running kinematics respectively, while 100 Hz was used for force plate data. Results: In ATR group, muscle strength there were no difference between affected and unaffected sides (p> .05). In kinematic analysis, subjects showed greater ROM of knee joint flexion-extension in affected side compared to that of unaffected side during walking while smaller ROM of ankle dorsi-plantar and peak knee flexion were observed during running (p< .05). In kinetic analysis, subjects showed lower knee extension moment (running at 2.2 m/s) and positive ankle plantar-flexion power (running at 2.2 m/s, 3.3 m/s) in affected side compared to that of unaffected side (p< .05). This lower positive ankle joint power during a propulsive phase of running is related to slower ankle joint velocity in affected side of the subjects (p< .05). Conclusion: This study aimed to investigate the functional evaluation of the individuals after Achilles tendon rupture surgery through biomechanical analysis during walking and running trials. Based on the findings, greater reduction in dynamic joint function (i.e. lower positive ankle joint power) was found in the affected side of the leg compared to the unaffected side during running while there were no meaningful differences in ankle muscle strength and walking biomechanics. Therefore, before returning to daily life and sports activities, biomechanical analysis using more dynamic movements such as running and jumping trials followed by current clinical evaluations would be helpful in preventing Achilles tendon re-rupture or secondary injury.

A Study on Evaluation of Slope Stability and Range of Rockfall Hazard of Daljeon-ri Columnar Joint in Pohang, Korea (천연기념물 제415호 포항 달전리 주상절리의 사면안정성 평가 및 낙석 위험 범위 설정)

  • Kim, Jae Hwan;Kang, Mu Hwan;Kong, Dal-Yong;Jwa, Yong-Joo
    • Journal of Conservation Science
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    • v.37 no.5
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    • pp.505-515
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    • 2021
  • In this study, we evaluated the slope stability of the Pohang Daljeon-ri columnar joint (Natural Monuments # 415) and calculated the maximum energy, jumping height and moving distance of rockfalls using a simulation. Based on the results, we established the range of rockfall risk. The slopes of the Pohang Daljeon-ri columnar joint have dip directions of 93.79°, 131.99°, 165.54° and 259.84° from left (SW) to right (NE). Furthermore, they have a fan-like shape. The Pohang Daljeon-ri columnar joints are divided into four sections depending on the dip direction. The measurement results of the discontinuous face show that zone 1 is 125, zone 2 is 261, zone 3 is 262, zone 4 is 43. The results of slope stability analyses for each section using a stereographic projection method correspond to the range of planar and toppling failure. Although it is difficult to diagnose the type of failure, risk evaluation of currently falling rocks requires further focus. The maximum movement distance of a rockfall in the simulation was approximately 66 m and the rockfall risk range was the entire area under slope. In addition, it is difficult to forecast where a rock will fall as it rolls in various directions due to topographic factors. Thus, the installation of measures to prevent falling is suggested to secure the stability based on the results of the rockfall simulations and its probabilistic analysis.

The Multi-Scalar Practices of the Labour and Economic Geography of TNCs: A Study on the Labour Geography of Nestlé Korea (노동자들의 다중스케일적 실천과 초국적 기업의 경제지리: 한국네슬레노동조합의 노동지리를 사례로)

  • Hwang, Jin-Tae
    • Journal of the Economic Geographical Society of Korea
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    • v.24 no.1
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    • pp.52-75
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    • 2021
  • The current Korean labour movement is at an impasse that is partly sustained by the idea of "strong" transnational corporations (TNCs) versus "weak" labour, and this perception is based on the "global-local dichotomy," wherein TNCs are depicted as abstract and structured entities operating at the global scale and workers are represented as having a concrete and weak presence within the local sphere. As an alternative perspective to break this "global" capital vs. "local" labour dichotomy, I focus on labour geography, which assumes that labour is not simply a factor of production but a sentient spatial actor that (un-)intentionally produces the landscape of capitalism. Borrowing insights from the multi-scalar perspective, this paper aims to understand the actual methods in which workers utilize spatial strategies through an empirical case study of the Nestlé Korea labour union strike in 2003. Based on this case study, this paper claims that workers are both capable of employing coordinated multi-scalar practices and can be more influential to the economic geographies of TNCs. Additionally, it suggests that workers' scalar practices are actually more complicated and multi-directional as a result of their complex and dynamic interactions with political, economic and cultural forces and actors at diverse geographical scales.

Effects of visual selection and rotation order on take-off and landing during sequential rotational jumping (연속 회전점프 시 시각선택과 회전순서가 도약과 착지에 미치는 영향)

  • Woo, Byung-Hoon
    • Journal of the Korean Applied Science and Technology
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    • v.39 no.5
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    • pp.701-709
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    • 2022
  • The purpose of this study was to compare the differences according to the visual selection and rotation order during sequential rotational jump for female dancers of a Korean ballet company by classifying them into take-off and landing sections. 10 subjects (age: 26.0±2.9 yrs, height: 163.4±3.3 cm, weight: 46.8±3.6 kg, ballet career: 12.3±5.9 yrs) participated in the study. Using a 3D motion analyzer and a force platform, the height of the body center and the ground reaction force during take-off and landing were measured. According to the visual condition (using both eyes, using left eye, using right eye) and rotation order (first rotation, second rotation), it was analyzed through repeated measurement two-way analysis. Height of the CM was higher in the first jump. In take-off, Fx was lateral force of left foot and medial force of right foot were strong in second rotation, and Fy was forward force was strong in first rotation of right foot. Fz was no significant. In landing, Fy showed backward force was strong when landing the second time from the left foot, and the backward force was strong when using the left sight from the right foot. Fz was strong on the second landing on the left foot and the first landing on the right foot.

Analysis of Rana coreana Behavior According to the Slope Angle Degree of Escape Ramp (콘크리트 수로 탈출로 경사각에 따른 한국산개구리 행동 분석)

  • Lee, Taeho;Kim, Jungkwon;Seo, Jihye;Jang, Moonjeong;Choi, Taeyoung;Chang, Minho
    • Journal of Environmental Impact Assessment
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    • v.31 no.1
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    • pp.75-81
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    • 2022
  • The purpose of this study is to propose the angle-limit of the escape ramp by analyzing the frog behavior characteristics according to the inclination angle of the waterway escape ramp installed in the concrete U-bench plume pipe channel. Forthe experiment, an escape test device was manufactured with the same shape and number of materials applied in the field. And Rana coreana living in paddy wetlands were sel selected. The main behaviors of frogs on the slope were 'jumping', 'crawling' and 'slipping', and afterrecording the behavioralresults according to the inclination angle, statistical analysis was conducted using the chi-square test method. As a result of the analysis, there was no statistically significant difference between 30° and 40°. This result is an evidence for expanding the standard of inclination angle 30° suggested in the 'Guidelines for Installation and Management of Ecological Pathways' to a maximum of 40°. However, further research is required in that the escape ramp targets not only Korean frogs but also various small wild animals. However, considering that various wild animals are affected by artificial canals, additional studies using various target wild animals are needed.

Political Economic Analysis of the Central Bank Digital Currency (중앙은행 디지털 화폐에 대한 정치경제학적 분석)

  • YoungBin Hahn
    • Analyses & Alternatives
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    • v.7 no.2
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    • pp.147-178
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    • 2023
  • While most of countries today are opposing the issuance of private-led cryptocurrency, nevertheless they are actively jumping into the issuance of government-led digital currency such as CBDC. This article aims to find an answer to this dual attitude of countries. To achieve the purpose, this article finds out the characteristics of political power and economic interest that digital currency has and applies it to the international dimension of the Bretton Woods II System. Then come up to the conclusion that the answer can be found in the fact that the current dual attitude of countries is closely related to the crisis of the international monetary order. The Bretton Woods II System, which led the world economy through reckless monetary expansion based on credit currency, exposed its limitations through the 2008 global financial crisis and put countries into difficulties. In this situation, the cryptocurrency, which appeared by raising the issue of the monopoly power of the central authority in issuing currency, had no choice but to act as an opportunity to drive countries further and further into a corner. This article views CBDC as a national response to address these issues. In other words, countries maintain their monetary power by absorbing the challenge of private digital currency at the government level through CBDC, and use this as a stepping stone to reorganize the international monetary order in crisis with the intention to use it as a means to their advantage. That is what this article is trying to argue.