• Parasites, Hosts and Diseases
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• 제60권5호
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• pp.309-315
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• 2022

Inflammatory bowel disease (IBD) is a chronic and recurrent illness of the gastrointestinal tract. Treatment of IBD traditionally involves the use of aminosalicylic acid and steroids, while these drugs has been associated with untoward effects and refractoriness. The absence of effective treatment regimen against IBD has led to the exploration of new targets. Parasites are promising as an alternative therapy for IBD. Recent studies have highlighted the use of parasite-derived substances, such as excretory secretory products, extracellular vesicles (EVs), and exosomes, for the treatment of IBD. In this report, we examined whether EVs secreted by Giardia lamblia could prevent colitis in a mouse model. G. lamblia EVs (GlEVs) were prepared from in vitro cultures of Giardia trophozoites. Clinical signs, microscopic colon tissue inflammation, and cytokine expression levels were detected to assess the effect of GlEV treatment on dextran sulfate sodium (DSS)-induced experimental murine colitis. The administration of GlEVs prior to DSS challenge reduced the expression levels of pro-inflammatory cytokines, including tumor necrosis factor alpha, interleukin 1 beta, and interferon gamma. Our results indicate that GlEV can exert preventive effects and possess therapeutic properties against DSS-induced colitis.

• Journal of Physiology & Pathology in Korean Medicine
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• 제36권4호
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• pp.143-146
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• 2022

This study aims to report a case of facial dermatitis herpetiformis with allergy diseases improved by administration of Mahaengeuigam-tang (Maxingyigan-tang). Multiple blisters appeared on the patient's face, Erythema, papules, and scales were also observed on the neck, back, and knee areas of the patient. The patient has had cough, sputum, and dyspnea symptoms since she was 5-6 months old. After diagnosing the patient's condition as dermatitis herpetiformis, atopic dermatitis, and bronchial asthma through history taking and symptom observation, Mahaengeuigam-tang (Maxingyigan-tang) was prescribed for about 30 days. As a result of evaluation through our own criteria, dermatitis herpetiformis symptoms improved from 18 to 2 points. Atopic dermatitis and asthma symptoms also decreased from 12 to 0 and 20 to 3 points, respectively. Since this study has proven the efficacy of Mahaengeuigam-tang (Maxingyigan-tang) for dermatitis herpetiformis patient, this prescription may be fully utilized as the treatment for other inflammatory skin diseases.

• Journal of Korea Entertainment Industry Association
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• 제13권1호
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• pp.139-156
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• 2019

The purpose of this study was to provide a method to support customized weather and environmental information services for the successful operation of winter sporting events. First, individual in-depth interviews and surveys were conducted with athletes, coaching staffs and experts related to the competition for 10 different winter sports for analysis of their needs. We conducted face-to-face survey and survey considering the training schedule and situation of experts. The recorded voice file was converted into word text, and extracted the weather and environmental information elements embedded in the opinions of the research participants based on literature reviews and data. The findings are expected to provide basic data on the weather conditions required to support specialized weather information for future large winter sports events, including the PyeongChang Winter Olympics.

• Physical Therapy Korea
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• 제30권2호
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• pp.144-151
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• 2023

Background: The gluteus maximus (GM) muscle comprise the lumbo-pelvic complex and is an important stabilizing muscle during leg extension. In patients with low back pain (LBP) with weakness of the GM, spine leads to compensatory muscle activities such as instantaneous increase of the erector spinae (ES) muscle activity. Four-point kneeling arm and leg lift (FKALL) is most common types of lumbopelvic and GM muscles strengthening exercise. We assumed that altered hip position during FKALL may increase thoraco-lumbar stabilizer like GM activity more effectively method. Objects: The purpose of this study was investigated that effects of the three exercise postures on the right-sided GM, internal oblique (IO), external oblique (EO), and multifidus (MF) muscle activities and pelvic kinematic during FKALL. Methods: Twenty eight healthy individuals participated in this study. The exercises were performed three conditions of FKALL (pure FKALL, FKALL with 120° hip flexion of the supporting leg, FKALL with 30° hip abduction of the lifted leg). Participants performed FKALL exercises three times each condition, and motion sensor used to measure pelvic tilt and rotation angle. Results: This study demonstrated that no significant change in pelvic angle during hip movement in the FKALL (p > 0.05). However, the MF and GM muscle activities in FKALL with hip flexion and hip abduction is greater than pure FKALL position (p < 0.001). Conclusion: Our finding suggests that change the posture of the hip joint to facilitate GM muscle activation during trunk stabilization exercises such as the FKALL.

• Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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• 제7권11호
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• pp.515-524
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• 2017

In this paper, we design and implement an expert system for diagnosing ADHD. As a result of the analysis with DSM-IV-TR, the ADHD diagnostic criteria are changed according to the age group. With this analyzed diagnostic, objects and their values are set and rules are created. We design a diagnostic system consisting of 'ADHD diagnostic system engine' and 'user query response program'. The ADHD diagnostic system engine is a rule-based reasoning engine that is implemented in the Prolog language and receives INPUT from the user query response program. By INPUT, the rule is executed based on the ADHD diagnostic criteria and the OUTPUT is sent back to the 'user query response program' by inferring the diagnostic result. The 'user query response program' is implemented in the Python language and serves as an interface for handling conversation with the user. The bridge between 'ADHD diagnostic system engine' and 'user query response program' is performed through the Pyswip library. As a result, the ADHD Diagnostic Expert System will help you plan your treatment with reduced diagnostic costs and use-complexity.

• 한국체육학회지인문사회과학편
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• 제54권5호
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• pp.607-618
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• 2015

This study aims to investigate overall factors regarding participation process such as process to pro-environmental behavior, pro-environmental behavior, continuing factors and constraint factors of outdoor recreation participants, and to determine logical correlation between them in order to make a theory model. To this end, grounded theory approach is applied for interpretation. First, pro-environmental behavior of outdoor recreation participants was formed by sequential influence of causal conditions and situational context. Second, outdoor recreation participants who participated in pro-environmental behavior of central phenomenon experienced peculiar continuing factors and constraint factors but it was found they also experienced general continuing factors and constraint factors. Third, it was analyzed that resultant settlement of pro-environmental leisure activities was partially fed back to the participation continuing factors of mediating conditions and a club of interaction strategy. Result from this study will give a help to widely understand experience of participation in leisure and restraints on leisure of outdoor recreation participants, and to development of study through organic combination between subsequent researches.

• Journal of the Korean Recycled Construction Resources Institute
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• 제11권3호
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• pp.267-275
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• 2023

The cement industry has been contributing to solve the wastes problem by using various combustible wastes as alternative fuel to replace natural coal. To use more alternative fuels such as waste plastics, in the cement manufacturing process, it is necessary to stably burn alternative fuels and reduce air emissions such as NOx. This study is a case study on the multi-stage combustion calciner process, which is a technology that decreases the amount of NOx while increasing the use of alternative fuels. This study is a case study on the multi-stage combustion process, a technology that reduces the amount of harmful air emissions such as NOx while increasing the use of alternative fuels. Along results of comparing before and after applying the technology to actual cement manufacturing facilities, the amount of coal consumption decreased by 38 %, waste plastics consumption increased by 122 %, and NOx emissions decreased by 17 %. Results show that increasing the use of alternative fuels and reducing NOx emissions by multi-stage combustion is effective.

• Parasites, Hosts and Diseases
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• 제61권4호
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• pp.418-427
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• 2023

Toxoplasma gondii infections are primarily diagnosed by serological assays, whereas molecular and fluorescence-based techniques are garnering attention for their high sensitivity in detecting these infections. Nevertheless, each detection method has its limitations. The toxoplasmosis detection capabilities of most of the currently available methods have not been evaluated under identical experimental conditions. This study aimed to assess the diagnostic potential of enzyme-linked immunosorbent assay (ELISA), real-time polymerase chain reaction (RT-PCR), immunohistochemistry (IHC), and immunofluorescence (IF) in BALB/c mice experimentally infected with various doses of T. gondii ME49. The detection of toxoplasmosis from sera and brain tissues was markedly enhanced in mice subjected to high infection doses (200 and 300 cysts) compared to those subjected to lower doses (10 and 50 cysts) for all the detection methods. Additionally, increased B1 gene expression levels and cyst sizes were observed in the brain tissues of the mice. Importantly, IHC, IF, and ELISA, but not RT-PCR, successfully detected T. gondii infections at the lowest infection dose (10 cysts) in the brain. These findings may prove beneficial while designing experimental methodologies for detecting T. gondii infections in mice.

• Structural Engineering and Mechanics
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• 제88권2호
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• pp.169-178
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• 2023

Lightweight aggregate concrete (LWAC) has various advantages, but it has limitations in ensuring sufficient ductility as structural members such as reinforced concrete (RC) columns due to its low confinement effect of core concrete. In particular, the confinement effect significantly decreases as the axial load increases, but studies on evaluating the ductility of RC columns at high axial loads are very limited. Therefore, this study examined the effects of concrete unit weight on the seismic performance of RC columns subjected to constant axial loads applied with different values for each specimen. The column specimens were classified into all-lightweight aggregate concrete (ALWAC), sand-lightweight aggregate concrete (SLWAC), and normal-weight concrete (NWC). The amount of transverse reinforcement was specified for all the columns to satisfy twice the minimum amount specified in the ACI 318-19 provision. Test results showed that the normalized moment capacity of the columns decreased slightly with the concrete unit weight, whereas the moment capacity of LWAC columns could be conservatively estimated based on the procedure stipulated in ACI 318-19 using an equivalent rectangular stress block. Additionally, by applying the section lamina method, the axial load level corresponding to the balanced failure decreased with the concrete unit weight. The ductility of the columns also decreased with the concrete unit weight, indicating a higher level of decline under a higher axial load level. Thus, the LWAC columns required more transverse reinforcement than their counterpart NWC columns to achieve the same ductility level. Ultimately, in order to achieve high ductility in LWAC columns subjected to an axial load of 0.5, it is recommended to design the transverse reinforcement with twice the minimum amount specified in the ACI 318-19 provision.

• The Journal of Internal Korean Medicine
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• 제45권2호
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• pp.131-139
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• 2024

In this case report, we describe the effects of Korean Medicine therapies, including Bunshimgi-eum, on a patient hospitalized with insomnia due to fibromyalgia in a Korean Medicine Hospital. We treated the patient with Bunshimgi-eum for 21 of 27 hospital days. Post-treatment, we used the Insomnia Severity Index (ISI) to measure the severity of insomnia. To determine the severity of multiple pain, including neck, low back, Lt. shoulder, Lt. elbow, Rt. knee, and hand, we used the Numerical Rating Scale (NRS). For evaluation of generic health status, we used the European Quality of Life-5 Dimensions (EQ-5D) scale. After the treatment, the patient's clinical symptoms improved, according to the ISI, NRS, and EQ-5D. The results of this case study suggest that Korean Medicine therapies, including Bunshimgi-eum, may have positive effects as a treatment for insomnia related to fibromyalgia.