• 한국한의학연구원논문집
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• 제14권3호
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• pp.127-135
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• 2008

The Korean Medicine Information has recently started due to lack of understanding and budgets. In this paper, the active region of Korean Medicine Information from outstanding cases in Korea and the trends of other nations was surveyed. As a results we found the problems that the available data is insufficient, the quality of data is not good and the unification of data is not easy from the analysis of information status and suggested the new directions. we suggest that Korea Medicine Information Center should be established to unify the information from Korea Medicine Organizations and to build information gathering network. we also suggest that well-organized information projects must be carried out in leadership of it from unified point of view. we mentioned the effects of Korea Medicine Information Center establishment.

• 한국한의학연구원논문집
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• 제13권2호통권20호
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• pp.127-133
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• 2007

Objectives : This study were aimed to estimate the needs for clinical research educational program development focused on oriental medicine. Methods : Department Medical Research of Korea Institute of Oriental Medicine surveyed 204 certified subjects in total by using web-based questionnaires through e-mail from Jan. 17th to Jan. 31th, 2007. Reply from 62 on-line correspondents were collected and statistically analyzed. Results : The number of clinical trial involving oriental medicine continues to increase. According to the survey, many Issues were raised as problems such as difficulty of recruitment, lack of fund and lack of stepped program. Emphasized issues were clinical research methodologies, development of protocols and case report form (CRF), and Regulations including Institutional Review Boards (IRBs) in these three consecutive education training program. Conclusion : The results of this study may contribute to the development of an educational program for oriental medicine, a program that should be taken into consideration for developing practical items, such as, problem-based learnings which reflects participants' actual needs in their works. Also this report be used for future strategy plans and execution of training program for oriental medical clinical trial.

• 대한예방한의학회지
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• 제13권3호
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• pp.1-18
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• 2009

Objectives : In this study, we survey papers about the combined therapy of oriental medicine and western medicine in oriental medicine viewpoint. Methods : First, we collected research papers on combined treatment, and we found 70 papers in the two internet sites, 'OASIS' and 'KISTI', using the keywords 'combined treatment', 'collaborated diagnosis', 'oriental-western medicine', and 'western-oriental medicine'. Then we analyzed them according to year, oriental-western medicine, diseases, research methods and subjects. Results & Conclusions : Researches for combined therapy had some problems as follows : First, studies have been made only for limited diseases like cancer, infection, stroke, etc. Second, methods of research are also limited. Some methods such as in vivo, in vitro and case-report are used repeatedly. Third, only the positive aspects of the combined therapy are proposed. We don't find the side effects of the combined therapy at all. To solve these problems, more objective and balanced studies such as RCT for various diseases should be performed.

• 동의생리병리학회지
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• 제21권1호
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• pp.263-269
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• 2007

In Korea, Korean Medicine is the first choice in treating stroke. Because stroke prognosis, risk of recurrence, and choices for management are influenced by stroke subtype, correct analysis of stroke subtype is important. Until now, the studies on differentiation of the symptoms and signs for the stroke were a few and the Korean standard differentiation of the symptoms and signs for the stroke don't exist. To develop the Korean standard differentiation of the symptoms and signs for the stroke, we go through subtype of stroke in traditional chinese medicine, Korean Medicine, western medicine.

• 한국한의학연구원논문집
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• 제18권3호
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• pp.127-132
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• 2012

Background and Purpose : This study was to investigate statistical validities and trends of previously reported papers that used various statistical techniques such as t-test and analysis of variance. Methods : To analyze the statistical procedures, 38 original articles using those statistical methods were selected from Journal of Korea Institute of Oriental Medicine(JKIOM) published from 2010 to 2012. Results : Analysis of variance and t-test were used in 20 papers (38.5%), 16 papers (30.8%) of 52 papers. Four articles(10.5%) did not report ${\alpha}$ values and nineteen papers(50.0%) of 38 ones were not tested for normal distribution. Five papers (13.2%) misused t-test and 3 papers (7.9%) did not carry out the multiple comparison. Conclusions : To improve the quality of JKIOM, The participation of statisticians in research design will reduce the significant errors in statistical interpretation of the results.

• 한국한의학연구원논문집
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• 제10권2호
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• pp.109-119
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• 2004

The aim of this study is to confirm clinical usefulness of MCG data by analyzing korea medical results of heart disease patients. We used the Heart Disease Questionnaire which asks for Qi deficiency-pattern, Blood deficiency-pattern, Yin deficiency-pattern, Yang deficiency-pattern, Qi stasis-pattern, Blood stasis-pattern, Heart heat-pattern, Phlegm-pattern. Magnetocardiography(MCG) is the measurement of magnetic fields emitted by the human heart from small currents by electrically active cells of the heart muscle. Comparing the MCG results and korea medical diagnosis, we showed clinical usefulness of MCG results and korea medical diagnosis.

• 한국한의학연구원논문집
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• 제14권2호
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• pp.41-46
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• 2008

The study was to investigate the agreement rate between the statistical diagnosis of pattern identification by discriminant analysis and the clinical diagnosis of pattern identification by medical specialist in obese patients with BMI$\geqq$23. The agreement rate of deficiency of the spleen, phlegm-retention, deficiency of Yang, retention of undigested food, stagnation of liver Gi, and blood stagnation are 0.40, 0.33, 0.52, 0.76, 0.71, and 0.66, respectively and accuracy rate and prediction rate using linear discriminant function are 0.59 and 0.61, respectively. Therefore, the complementary management in CRF questionnaires and/or consultation from experts will improve the accuracy and prediction rate, which will be helpful for pattern identification of obesity by clinical experts.

• 한국한의학연구원논문집
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• 제14권1호
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• pp.107-111
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• 2008

Objectives : Cynanchum wilfordii(Asclepiadaceae) has been traditionally used as a tonic, the prevention and treatment of various geriatric diseases in Korea. Acetophenone derivatives from C. wilfordii showed neuroprotective activity. In this study, two acetophenones were isolated and quantitative determination of acetophenones from C. wilfordii has been developed for quality stand. Methods : Three acetophenone derivatives were isolated from methanol extract of C. willfordii by the chromatographic separation. Their structures were identified as cynandione A, 2,5-dihydroxy acetophenone and cynanchone A on the basis of spectral data(MS, $^1H-NMR$, $^{13}C-NMR$) and chemical analysis. HPLC analysis was performed to determine the contents of cynandione A and 2,5-dihydroxyacetophenone in C. wilfordii. Results : According to the results, the contents of cynandione A and 2,5- dihydroxyacetophenone were 0.274%, 0.035% by HPLC, respectively. Conclusions : In these results, we have determined the contents of cynandione A and 2,5-dihydroxyacetophenone in Cynanchum wilfordii, respectively. We hope that this study will contribute to the standardization and quality control of herbal medicine.

• 한국한의학연구원논문집
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• 제13권3호
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• pp.11-20
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• 2007

Haedae(海帶, haidai) is representative herb from seaweeds, but its origin is still confusing. Thus we analyzed its origin on the basis of classics of oriental medicine. The scientific name of Haedae corresponds to Zostera marina, according to the folkloric use. But, it is Laminaria japonica, according to its habitat, morphological feature, and the korean name on the medical books in Joseon since 17c. In the remote past, it seemed that two groups were segragated by the name of Zostera marina Haedae and Laminaria japonica Haedae. However, it is thought that this two trends were mixed up when medical knowledge was compiled in Song Dynasty era. Documental support inclined to Laminaria japonica, but it is too early to conclude that Laminaria japonica is the Haedae. To prove this hypothesis, further study is required to investige whether Laminaria japonica or Zostera marina has mentioned efficacies of Haedae used for the treatment of wen, San syndromes, edema, scrofula, etc. And we have need of research that solve the origin problem of Gonpo(Laminariae thallus) on the assumption that Laminaria japonica is Haedae.

• 동의생리병리학회지
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• 제20권6호
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• pp.1789-1792
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• 2006

To develop the Korean Standard Differentiation of the symptoms and signs for the Stroke(KSDS), the committee on Stroke Diagnosis Standardization of Korean Traditional Medicine was organized by nineteen experts in College of Korean Medicine, The Consensus of the second Consultation Meeting was as follows : First is the definition of the stroke on the Korean Traditional Medicine. Second is the five categories to the Differentiation of the symptoms and signs for the Stroke - fire and heat, dampness and phlegm, blood stasis, qi deficiency, yin deficiency. Third is the indices of the Differentiation of the symptoms and signs for the Stroke respectively. KSDS-1 will be applied to the clinical practice and revised. The Consensus of the third Consultation Meeting had agreed 81 symptoms indexes of KSDS.