• Title/Summary/Keyword: Joint development

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Screening and Development of Novel Herbal Medicine for Bone Healing Treatment (골유합 촉진 치료제 개발을 위한 수종의 한약재 활성 검색)

  • Lee, Jae-Dong;Baek, Yong-Hyeon;Choi, Do-Young;Huh, Jeong-Eun;Yang, Ha-Ru;Woo, Hyun-Su;Park, Dong-Suk
    • Journal of Acupuncture Research
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    • v.24 no.5
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    • pp.13-22
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    • 2007
  • Objectives : The differentiation of osteoblasts is controlled by various growth factors and matrix protein expressed in bone. The aim of this study was to investigate the effects of many herbs medicine(KHBJs) for bone healing that induces osteogenic activity in human osteoblast-like SaOS-2 cells. Methods : The osteogenic effects of KHBJs were evaluated by using cell proliferation(WST-8) assay, alkaline phosphatase(ALP) activity assay, colorimetric analysis of vascular endothelial growth factor(VEGF) expression in human osteoblast like SaOS-2 cell. Also, osteogenic activity of KHBJ fractions(KHBJB and KHBJR) by activity guided fractionation were evaluated. Results : About 7 KHBJs had effect on the proliferation of osteoblast like SaOS-2 cells, and dose-dependently increased alkaline phosphatase(ALP) activity. KHBJs markedly increased expression for VEGF. Fractionated KHBJs(KHBJB or KHBJR) not enhanced more than KHBJs on osteogenic activity in SaOS-2 cells. Conclusions: This study found that 7 KHBJs had effect on proliferation, ALP activity, and VEGF expression in osteoblast like SaOS-2 cells. These results propose that KHBJs can play an important role in osteoblastic bone formation, and may possibly lead to the development of bone-forming drugs.

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Development and Examination of the Online and Offline Educational Programs for Ankylosing Spondylitis Patients (강직성 척추염 환자의 오프라인 교육과 온라인 교육 프로그램 개발 및 효과 검증)

  • Lee, In-Ok;Lee, Eun-Ok
    • Journal of muscle and joint health
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    • v.10 no.2
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    • pp.167-187
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    • 2003
  • Ankylosing spondylitis(AS) is one of the most common forms of chronic arthritis causing pain and progressive disability. The purposes of this study were 1) to develop an offline educational program and online educational program for the patients with ankylosing spondylitis; and 2) to test the effectiveness of each program in terms of changes in ankylosing spondylitis self-efficacy, exercise continuity disease activity, physical functioning, and depression. The convenient samples for three groups were selected acceding to the inclusion criteria. Online education group consists of 7 patients, and 14 patients were included for the offline group, while 12 patients were assigned to the control group. Outcomes variables included self efficacy, exercise continuity, disease activity, physical function, and depression and the reliability of each measure was ranged from .88 to .95 in the present study. The offline educational program demonstrated positive effects on self-efficacy, exercise continuity, disease activity, and depression, whereas the online educational program on exercise continuity, disease activity, and depression. The self-efficacy was showed positive effect only in the offline educational program, whereas physical functioning did not improve in both intervention groups. These partial improvements may be due to the small sample size and the methods of online education program. In conclusion, the effectiveness of the offline and online educational programs was partially supported in the present study. For the improvement of these programs, the further study would be necessary to apply this kind of intervention program with larger sample and to test the psychometric of the newly development tools.

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History of Acupuncture Medicine Witnessed the Setting of Modern Set of 361 Acupoints in the Classical Title of 19th Century, 『Exploring the Origin of Acupuncture Medicine (針灸逢源)』 (현대 361개 경혈체계를 마련한 19세기 『침구봉원』의 침구의학과 침구경락 음양론 발전상 의의)

  • Jung, Il Kyung;Lee, Hyejung;Yin, Chang Shik
    • Journal of TMJ Balancing Medicine
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    • v.9 no.1
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    • pp.1-3
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    • 2019
  • Objectives: "Exploring the origin of acupuncture medicine (針灸逢源)", a classical title of acupuncture medicine in the 19th century, has been reviewed with focus on its impact on the standardization of acupoint in the history of acupuncture medicine as an approach of yin-yang balancing medicine like the Temporomandibular joint Balancing Medicine. Methods: A narrative review of literature was performed with a focus on continuous development and revision of the knowledge system of acupuncture medicine in medical education and clinical application. Results: This title has provided a systematized knowledge on acupoint-acupuncutre including 361 acupoints, acupoint location, and acupoint-meridian association, which was adopted as a frame of core knowledge in modern acupuncture medicine. Critical review and rational reasoning on previously accepted but apparently incongruous strips of knowledge led to the accomplishment of this title. Conclusions: This title provided a revised and standard knowledge system in the field of medical education and clinical practice of acupuncture medicine, and also provided an exemplary model of unrelenting change and development of an approach based on the concept of yin-yang balance such as acupuncture medicine and the Temporomandibular joint Balancing Medicine.

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Goal, Structure, and Recent Development of the GLOBEC Programme (GLOBEC 프로그램의 목적, 운영체계 및 최근의 동향에 대하여)

  • Kim, Su-Am
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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    • v.5 no.1
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    • pp.10-15
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    • 2000
  • Goals, research direction, and operational structure of the Global Ocean Ecosystem Dynamics (GLOBEC), which is co-sponsored by the Scientific Committee on Oceanic Research (SCOR) and the Intergovemmental Oceanographic Commission (IOC), are described. Following the Joint Global Ocean Flux Study (JGOFS) activities on the lower trophic level in ecosystem during 1980s-90s, scientists have considered the responses of the mid and higher trophic levels to the environmental or climate change. The scientific steering committee of the GLOBEC published the implementation plan in 1999, and the IGBP will support the GLOBEC as one of its core projects for 10 years. The GLOBEC programme has four major components: the research foci, framework activities, regional programmes, and integrating activity. The core of GLOBEC research is the four research foci: retrospective analyses, process studies, predictive and modelling capabilities, and feedbacks. Currently, four regional programmes have been undergoing in the world ocean: Southern Ocean GLOBEC (SO-GLOBEC), Small Pelagic Fishes and Climate Changes (SPACC), Cod and Climate Change (CCC), and Climate Change and Carrying Capacity (CCCC). Also, national GLOBEC programmes were already established in 9 nations.

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Evaluation of the Weak Part for Wave Dissipating Blocks under Various Conditions: Tetrapod (다양한 하중 조건에서 Tetrapod 소파블록의 취약부 분석)

  • Lim, Jeong Hyeon;Won, Deokhee;Han, Taek Hee;Kang, Young-Jong
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.15 no.8
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    • pp.5385-5392
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    • 2014
  • Super typhoons develop as a result of meteorological changes. In 2012, Typhoons Bolaven and Denba reached Korea. The maximum instantaneous wind speed of the typhoons reached 60 m/sec. Harbor structures including sofa block sustained damage and loss by the abnormally high waves. In Korea, tetrapod blocks were installed the most for wave dissipating. Nevertheless, a structural evaluation of the tetrapod block has not been performed. This study examined the structural mechanism and weakness part of the tetrapod block under a range of boundary conditions. The block has weakness against a tensile force because it is plain concrete. The joint part of the legs is the most vulnerable to tensile stress. The weakest part can be reduced if the joint part is reinforced as a hunch.

Development of Evidence-based Guidelines for Nursing Home's Infection Control in Korea (한국형 노인요양시설 근거중심 감염관리 가이드라인 개발)

  • Park, Yeon-Hwan;Lee, Seong Hyeon;Yi, Yu Mi;Lee, Chi Young;Lee, Min Hye
    • Journal of muscle and joint health
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    • v.25 no.2
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    • pp.135-147
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    • 2018
  • Purpose: The purpose of this study was to develop evidence-based guidelines for infection control in nursing homes in Korea (ENIK). Methods: Three steps were planned for the development which were developing a draft and testing the content validity. First, the draft was based on evidence and developed through focus group interviews with nurses in nursing homes, a comprehensive review of international guidelines and literature, and systematic reviews of interventions for infection control and outbreaks in long-term care facilities. Clinical applicability was established through reviews of nursing records and job assignments in one nursing home. The final step consisted of experts evaluating the content validity. The ENIK was revised to fit Korean nursing homes. Results: The ENIK consisted of recommendations in 9 compositions and a one-page practical algorithm. The principles of infection control were presented by statements and specific strategies were recommended in resident care programs. The infection control practical algorithm was organized into 3 steps: screening at admission, prevention, and control at the early stage. The practice to control infection was composed of a 5-step process. Conclusion: The ENIK will contribute to improving the competency of infection control practice because it provides standardized practice and is tailored to Korean nursing homes.

Development of Gesture Recognition-Based 3D Serious Games (치매 예방을 위한 제스처 인식 기반 3D 기능성 게임 개발)

  • He, Guan-Feng;Park, Jin-Woong;Kang, Sun-Kyung;Jung, Sung-Tae
    • Journal of Korea Game Society
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    • v.11 no.6
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    • pp.103-113
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    • 2011
  • In this paper, we propose gesture recognition based 3D Serious Games to prevent dementia. These games are designed to enhance the effect of preventing dementia by helping increase brain usage and physical activities of users by the entire body gesture recognition. The existing cameras used for gesture recognition technology are limited in terms of recognition ratio and operation range. For more stable recognition of the body gestures, we recognized users with a 3D depth camera, obtained joint data of users, and analyzed joint motions to recognize gestures of the body. Game contents were designed to practice memory, reasoning, calculation, and spatial recognition focusing on the atrophy of brain cells as a major cause of dementia. Game results of each user were saved and analyzed to measure how their recognition skills improved.

Dissimilar Friction Stir Welding Characteristics of Mg Alloys(AZ31 and AZ61) (AZ31와 AZ61 마그네슘 합금의 이종 마찰교반용접 특성)

  • Park, Kyoung Do;Lee, Hae Jin;Lee, Dai Yeol;Kang, Dae Min
    • Journal of the Korean Society of Manufacturing Process Engineers
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    • v.16 no.5
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    • pp.99-104
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    • 2017
  • Friction stir welding is a solid-state joining process and is useful for joining dissimilar metal sheets. In this study, the experimental conditions of the friction stir welding were determined by the two-way factorial design to evaluate the characteristics of the dissimilar friction stir welding of AZ31 and AZ61 magnesium alloys. The levels of rotation speed and welding speed, which are welding variables, were 1000, 2000, 3000 rpm and 100, 200, 300 mm/min, respectively. From the results, the greater the rotation speed and the lower the welding speed of the tool were, the greater the tensile strength of the welded part was. The contribution of the welding speed of the tool is larger than that of the rotation speed of the tool. In addition, the optimal conditions for tensile strength in the dissimilar friction stir joint were predicted to be the rotation speed of 3000 rpm and welding speed of 100 mm/min, and the tensile strength under the optimal conditions was estimated to be $214{\pm}6.57Mpa$ with 99% reliability.

Opportunities for Joint Cooperation in R&D for FEALAC Countries: On Nanotechnology and Biotechnology

  • Trujillo, Ivan Montenegro;Jimenez, Edgar E Gonzalez;Ospina, Monica Botero
    • STI Policy Review
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    • v.7 no.2
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    • pp.106-131
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    • 2016
  • The general purpose of this paper is to identify opportunities for and to measure existing collaboration on research and development between institutions from the countries of Asia and Latin America in FEALAC's framework, in the fields of biotechnology and nanotechnology and their convergence. The methodological approach includes scientific and technological surveillance and research seeking to identify both the R&D and innovation capacities of the countries as well as the degree of international cooperation between countries of the two regions; case studies and a study of the governance framework of international collaboration in R&D about issues considered global challenges. The study has three main findings. First, nanotechnology, biotechnology and their convergence contribute to solving the problem of contamination by heavy metals affecting most of the countries that are part of FEALAC and to address problems arising from the accelerated rate of energy consumption, which also contributes to environmental damage. In this scenario, important business opportunities arise from the adaptation and development of bio-refinery technologies. Second, the scientific relationship between FEALAC countries, mainly between Asian and Latin American countries, is weak as can be seen in research for articles and patents. But there is plenty of room and potential for improvement. Third, current and upcoming joint R&D programs and projects should be linked both to existing governance structures and to new ones that serve as experiments of STI public policy regarding innovative management of intellectual property and capacity building. Practical implications are included in lessons learned and a set of recommendations involving a couple of proposals. One proposal calls for research and innovation in promising fields for international cooperation. Another proposal creates mechanisms in the governance framework for sharing knowledge, capacity building, and funding.

Development of Frozen Shoulder Rehabilitation Robot Based On Motion Capture Data (모션 캡쳐 데이터 기반의 오십견 재활 보조용 로봇의 개발)

  • Yang, Un-Je;Kim, Jung-Yup
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.36 no.9
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    • pp.1017-1026
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    • 2012
  • In this study, an exoskeleton-type robot is developed to assist frozen shoulder rehabilitation in a systematic and efficient manner for humans. The developed robot has two main features. The first is a structural feature: this robot was designed to rehabilitate both shoulders of a patient, and the three axes of the shoulder meet at one point to generate human-like ball joint motions. The second is a functional feature that is divided into two rehabilitation modes: the first mode is a joint rehabilitation mode that helps to recover the shoulder's original range of motion by moving the patient's shoulder according to patterns obtained by motion capture, and the second mode is a muscle rehabilitation mode that strengthens the shoulder muscles by suitably resisting the patient's motion. Through these two modes, frozen shoulder rehabilitation can be performed systematically according to the patient's condition. The development procedure is described in detail.