• Title/Summary/Keyword: Joint development

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Inhibitory Effects of Transforming Growth Factor and Drynariae Rhizoma on Leukocytosis Associated with the Chronic Phase of Arthritis in Mice

  • Bae Sung-Min;Jeong Ji-Cheon
    • The Journal of Korean Medicine
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    • v.25 no.4
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    • pp.26-35
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    • 2004
  • Drynariae Rhizoma (DR), an herbal medicine known to clean blood and improve its circulation, frequently appears as the main ingredient in the prescriptions for bone injuries. Currently, it is unclear how contributes pharmacologically to the reformation of bone. Therefore, we have done this study. Systematic administrations of TGFβ1 and water extract of DR diminished the polyarthritis development in rats. TGFβ administration (0.1-2 ㎍/animal) and DR (10-100 ㎍/animal), initiated 1 day before an arthritogenic dose of streptococcal cell wall fragments, virtually eliminated the joint swelling and distortion observed during the acute phase and the chronic phase of the disease. The TGFβ and DR synergistically suppressed the arthritis when the administration was begun after the acute phase of arthritis. Also, the synergistic activity between TGFβ and DR was confirmed in their suppression of arthritis in rats. Consistent with the inhibition of inflammatory cell recruitment into the synovium, TGFβ1 and DR reversed the leukocytosis associated with the chronic phase of the arthritis.

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Development of the Robotic Gait Trainer for Persons with Gait Disorder (보행 장애인을 위한 로봇형 보행훈련 시스템의 개발)

  • Hwang, Sung-Jae;Son, Jong-Sang;Kim, Jung-Yoon;Sohn, Ryang-Hee;Kim, Young-Ho
    • Proceedings of the KIEE Conference
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    • 2008.04a
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    • pp.73-74
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    • 2008
  • In this study, we developed a robotic gait trainer which induces the active gait training based on predefined continuous proper lower extremity joint movements. AC servo motors and linear actuators were used to control hip and knee joints of patients and the weight support system was used to support the patient's weight during the gait training. We also implemented a Gill program to set the gait training pattern with several training parameters and to confirm states of patients and the system through the visual feedback. The effectiveness of the gait training system will be determined by the long-term clinical experiments in the future. We expect that the developed robotic gait training system could be applied very practically to recover gait abilities for persons with gait disorder.

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A Case Study of Prosthetic Ambulation Training for Rotation-Plasty Client (하지 분절절제 및 회전재접합술자의 의지 보행훈련 증례연구)

  • Lee, Jeong-Weon;Chung, Nack-Su
    • Physical Therapy Korea
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    • v.3 no.1
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    • pp.65-72
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    • 1996
  • The purpose of this study was to introduce rotation-plasty procedure and prosthetic ambulation training. The recent development of chemotherapy and diagnostic facility have permitted the orthopaedic surgeons to try limb saving procedures rather than amputations for the treatment of the malignant bone tumors. If the tumors around the knee joint were treated by mid-thigh amputation or hip disarticulation, it would impose the client with a great handicap for rehabilitation. Rotation-plasty procedure was first done by Borggreve, in 1930 for the congenital short femur. Recently this procedure was used a malignant bone tumor at the distal femur by Kotz and Salzer in 1982. In spite of its cosmetic problem of the distal stump, this procedure has the great functional advantage of converting the above-knee amputation to the below-knee amputation. The inverted foot was also good to control the prosthesis as a below-knee stump and heel functioned as a patella to support the body weight. This 15 years old girl case was had rotation-plasty due to osteosarcoma of the distal femur with 3rd postoperative chemotherapy, and admitted to Yonsei rehabilitation hospital for prosthetic ambulation training. Then, the case had excellent functional results of prosthetic ambulation training with rotaion-plasty after 3 months.

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Development of a Powered Knee Prosthesis using a DC Motor (DC 모터를 이용한 동력 의족 시스템 개발)

  • Kim, Won-Sik;Kim, Seuk-Yun;Lee, Young-Sam
    • Journal of Institute of Control, Robotics and Systems
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    • v.20 no.2
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    • pp.193-199
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    • 2014
  • In this paper, we present an overview of the structure of a lab-built powered knee prosthesis and the control of it. We build a powered prosthesis prototype on the basis of previous researches and aim at obtaining the essential technology related with its control. We adopt the slider-crank mechanism with a DC motor as an actuator to manipulate the knee joint. We also build an embedded control system for the prosthesis with a 32-bit DSP controller as a main computation unit. We divide the gait phase into five stages and use a FSM (Finite State Machine) to generate a torque reference needed for each stage. We also propose to use a position-based impedance controller for driving the powered knee prosthesis stably. We perform some walking experiments at fixed speeds on a tread mill in order to show the feature of the built powered prosthesis. The experimental results show that our prosthesis has the ability to provide a functional gait that is representative of normal gait biomechanics.

Development of CAD tool for optimal spot weld joints (점용접 위치의 최적화를 위한 CAD Tool 개발)

  • Ryu, Si-Uk;Lee, Jong-Chan;Lee, Tae-Soo
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.22 no.1
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    • pp.148-159
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    • 1998
  • Spot welding palys a key role in increasing productivity and weight reduction of the final products. This paper proposes a systematic approach on the design of spot weld configuration, dealing with the requried number and location of spot weld joints under the given design parameters, such as the applied loads, lap area, and individual spot weld strength. The optimal design of a spot-welded joint is postulated as a state when the safety factors of all spot weld points (i) are evenly distributed and (ii) reach maximum value. A CAD program is developed to arrange the optimal location of each spot weld based on the derived objective function and constraints. The CAD tool integrates the optimization procedure with Finite Element Analysis (FEA) code through an interface. The interface automatically provides geometrical data and mesh configuration for different spot weld locations to FEA model. It also extracts the transmitted load of each spot weld from the FEA code, and allows the optimization code predict an improved arrangement of spot weld locations. The feasibility of the developed approach is demonstrated by the selected examples.

Image classification and captioning model considering a CAM-based disagreement loss

  • Yoon, Yeo Chan;Park, So Young;Park, Soo Myoung;Lim, Heuiseok
    • ETRI Journal
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    • v.42 no.1
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    • pp.67-77
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    • 2020
  • Image captioning has received significant interest in recent years, and notable results have been achieved. Most previous approaches have focused on generating visual descriptions from images, whereas a few approaches have exploited visual descriptions for image classification. This study demonstrates that a good performance can be achieved for both description generation and image classification through an end-to-end joint learning approach with a loss function, which encourages each task to reach a consensus. When given images and visual descriptions, the proposed model learns a multimodal intermediate embedding, which can represent both the textual and visual characteristics of an object. The performance can be improved for both tasks by sharing the multimodal embedding. Through a novel loss function based on class activation mapping, which localizes the discriminative image region of a model, we achieve a higher score when the captioning and classification model reaches a consensus on the key parts of the object. Using the proposed model, we established a substantially improved performance for each task on the UCSD Birds and Oxford Flowers datasets.

Ureterosciatic hernia causing obstructive uropathy successfully managed with minimally invasive procedures

  • Kim, Yeong Uk;Cho, Jae Ho;Song, Phil Hyun
    • Journal of Yeungnam Medical Science
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    • v.37 no.4
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    • pp.337-340
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    • 2020
  • Ureterosciatic hernia is extremely rare. In ureteral herniation, ureter prolapses occur through either the greater or lesser sciatic foramen. Atrophy of the piriformis muscle, hip joint diseases, and defects in the parietal pelvic fascia are predisposing factors for the development of ureterosciatic hernia. Most symptomatic patients have been treated surgically, with conservative treatment reserved only for asymptomatic patients. To the best of our knowledge, long-term follow-up outcomes after ureterosciatic hernia management are sparse. In this paper, we report the case of a 68-year-old woman who presented with colicky left abdominal pain. After computed tomography (CT) scan and anterograde pyelography, she was diagnosed ureterosciatic hernia with obstructive uropathy. We performed ureteral balloon dilatation and double-J ureteral stent placement. After this minimally invasive procedure, CT scan demonstrated that the left ureter had returned to its normal anatomical position without looping into the sciatic foramen. The patient remained asymptomatic with no adverse events 7 years after the minimally invasive procedures. This brief report describes ureterosciatic hernia successfully managed with minimally invasive procedures with long-term follow-up outcomes.

Development of the Conceptual Model of Constructing and Operating the Integrated Computing Environment (통합전산환경 구축$\cdot$운영을 위한 개념적 모형 개발)

  • Jung, Hae-Yong;Kim, Sang-Hoon
    • Journal of Information Technology Applications and Management
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    • v.12 no.4
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    • pp.173-195
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    • 2005
  • As the amount of informatization investment is rapidly increasing in many organizations, it becomes more inevitable to manage computing resources (information systems, computing facilities and manpower etc.) effectively. Specially, in public sector It is thought to be very important to achieve the economy of scale by integrating computing resources which are managed individually in many agencies. Also, our government have been recently making much efforts to raise the effectiveness of operating the information systems by promoting joint information use among many public agencies, enhancing the operating systems and the expertise of IS staff and applying the optimal information security systems. This study focuses on presenting the framework to effectively integrate omputing resources and proposing the ways of constructing and operating the integrated computing environment for the institutions and the affiliated groups under the Ministry of Culture & Tourism which are in charge of implementing cultural informatization. The main implications of this study are 1) building the ideal model of the integrated computing environment architecture suitable to cultural informatization area, 2) showing the criteria of deciding whether the organizations use the Integrated computing environment or not and how extensively they commit their computing resources to it, and 3) suggesting the ways of the phased integration and the change management to minimize confusion in the process of adopting the integrated computing environment and behavioral problems such as conflict and resistance of IS-related Personnel Influenced by Implementing the integrated computing environment.

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Development of a Graphic Simulation Modeller for Robot Welding Process Planning (로보트 용접 공정 계획을 위한 Graphic Simulation Modeller의 개발)

  • Choe, Byeong-Gyu;Jeong, Jae-Yun;Kim, Dong-Won
    • Journal of Korean Institute of Industrial Engineers
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    • v.11 no.1
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    • pp.21-32
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    • 1985
  • Presented in this paper is a procedure of developing graphical simulation software for planning robot welding processes. Welding is by far the highest application area for industrial robots, and it has been in great need of such a simulator in designing robot work cells, in justifying the economics of robot welding and in planning robotized welding operations. The model of a robot welding cell consists of four components: They are an welding structure which is a collection of plates to be welded, a positioner to hold the welding structure, a robot with a weld torch, and a set of welding lines (in case of arc welding). Welding structure is modeled by using the reference plane concept and is represented as boundary file which is widely used in solid modeling. Robot itself is modeled as a kinematic linkage system. Also included in the model are such technical constraints as weaving patterns and inclination allowances for each weld joint type. An interactive means is provided to input the welding structure and welding lines on a graphics terminal. Upon completion of input, the program displays the welding structure and welding lines and calculates the center of mass which is used in determining positioner configurations. For a given positioner and robot configuration, the welding line segments that can be covered by the robot are identified, enabling to calculate the robot weld ratio and cycle time. The program is written in FORTRAN for a VAX computer with a Tektronix 4114 graphic terminal.

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A Study on the Mechanical Properties of Joints in Laser Transmission Joining of Polymers (폴리머의 레이저 투과접합 시 접합부의 기계적 성질에 관한 연구)

  • Cha, Sang-Woo;Kim, Jin-Beom;Yoon, Suk-Hwan;Na, Suck-Joo
    • Journal of Welding and Joining
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    • v.25 no.2
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    • pp.43-48
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    • 2007
  • Laser Transmission Joining (LTJ) of plastics is a process in which light of suitable wavelength is transmitted through a transparent substrate that is in contact with an absorbing one. In this paper, LTJ is investigated by preliminary experiments from the viewpoint of mechanical engineering. To understand transmitting characteristics of each polymer substrate, transmission rate, reflection rate and absorption coefficient of polymer are measured by using a laser power-meter. Characteristics of joining in the spot welding and seam welding are investigated by measuring the fracture load. Fracture load increases in accordance to the laser power and irradiation time. However, when the laser power is over 60W and irradiation time over 4seconds, fracture load decreases. This phenomenon is probably due to heat-softening of materials. Besides, cavities are generated at a joint by evaporation of water molecules, which can be suppressed by introduction of a gap between two substrates.