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A MEASURE ZERO STABILITY OF A FUNCTIONAL EQUATION ASSOCIATED WITH INNER PRODUCT SPACE

  • Chun, Jaeyoung;Rassias, John Michael
    • Journal of the Korean Mathematical Society
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    • v.54 no.2
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    • pp.697-711
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    • 2017
  • Let X, Y be real normed vector spaces. We exhibit all the solutions $f:X{\rightarrow}Y$ of the functional equation f(rx + sy) + rsf(x - y) = rf(x) + sf(y) for all $x,y{\in}X$, where r, s are nonzero real numbers satisfying r + s = 1. In particular, if Y is a Banach space, we investigate the Hyers-Ulam stability problem of the equation. We also investigate the Hyers-Ulam stability problem on a restricted domain of the following form ${\Omega}{\cap}\{(x,y){\in}X^2:{\parallel}x{\parallel}+{\parallel}y{\parallel}{\geq}d\}$, where ${\Omega}$ is a rotation of $H{\times}H{\subset}X^2$ and $H^c$ is of the first category. As a consequence, we obtain a measure zero Hyers-Ulam stability of the above equation when $f:\mathbb{R}{\rightarrow}Y$.

Identification of flutter derivatives from full-scale ambient vibration measurements of the Clifton Suspension Bridge

  • Nikitas, Nikolaos;Macdonald, John H.G.;Jakobsen, Jasna B.
    • Wind and Structures
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    • v.14 no.3
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    • pp.221-238
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    • 2011
  • The estimated response of large-scale engineering structures to severe wind loads is prone to modelling uncertainties that can only ultimately be assessed by full-scale testing. To this end ambient vibration data from full-scale monitoring of the historic Clifton Suspension Bridge has been analysed using a combination of a frequency domain system identification method and a more elaborate stochastic identification technique. There is evidence of incipient coupling action between the first vertical and torsional modes in strong winds, providing unique full-scale data and making this an interesting case study. Flutter derivative estimation, which has rarely previously been attempted on full-scale data, was performed to provide deeper insight into the bridge aerodynamic behaviour, identifying trends towards flutter at higher wind speeds. It is shown that, as for other early suspension bridges with bluff cross-sections, single-degree-of-freedom flutter could potentially occur at wind speeds somewhat below requirements for modern designs. The analysis also demonstrates the viability of system identification techniques for extracting valuable results from full-scale data.

AltMV TGB1 Nucleolar Localization Requires Homologous Interaction and Correlates with Cell Wall Localization Associated with Cell-to-Cell Movement

  • Nam, Jiryun;Nam, Moon;Bae, Hanhong;Lee, Cheolho;Lee, Bong-Chun;Hammond, John;Lim, Hyoun-Sub
    • The Plant Pathology Journal
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    • v.29 no.4
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    • pp.454-459
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    • 2013
  • The Potexvirus Alternanthera mosaic virus (AltMV) has multifunctional triple gene block (TGB) proteins, among which our studies have focused on the properties of the TGB1 protein. The TGB1 of AltMV has functions including RNA binding, RNA silencing suppression, and cell-to-cell movement, and is known to form homologous interactions. The helicase domains of AltMV TGB1 were separately mutated to identify which regions are involved in homologous TGB1 interactions. The yeast two hybrid system and Bimolecular Fluorescence Complementation (BiFC) in planta were utilized to examine homologous interactions of the mutants. Helicase motif I of AltMV TGB1 was found to be critical to maintain homologous interactions. Mutations in the remaining helicase motifs did not inhibit TGB1 homologous interactions. In the absence of homologous interaction of TGB1, subcellular localization of helicase domain I mutants showed distinctively different patterns from that of WT TGB1. These results provide important information to study viral movement and replication of AltMV.

Numerical simulations of deep penetration problems using the material point method

  • Lorenzo, R.;da Cunha, Renato P.;Cordao Neto, Manoel P.;Nairn, John A.
    • Geomechanics and Engineering
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    • v.11 no.1
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    • pp.59-76
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    • 2016
  • Penetration problems in geomechanics are common. Usually the soil is heavily disturbed around the penetrating bodies and large deformations and distortions can occur. The simulation of the installation of displacement piles is a good example of the interest of these types of problems for geomechanics. In this paper the Material Point Method is used to overcome the difficulties associated with the simulations of problems involving large deformation and full displacement type penetration. Recent modifications of the Material Point Method known as Generalized Interpolation Material Point and the Convected Particle Domain Interpolation are also used and evaluated in some of the examples. Herein a footing submitted to large settlements is presented and simulated, together with the processes associated to a driven pile under undrained conditions. The displacements of the soil surrounding the pile are compared with those obtained by the Small Strain Path Method. In addition, the Modified Cam Clay model is implemented in a code of MPM and used to simulate the process of driving a pile in dry sand. Good and rather encouraging agreement is found between compared data.

Mayamaea vietnamica sp. nov.: a new, terrestrial diatom (Bacillariophyceae) species from Vietnam

  • Kezlya, Elena;Glushchenko, Anton;Kociolek, John Patrick;Maltsev, Yevhen;Martynenko, Nikita;Genkal, Sergei;Kulikovskiy, Maxim
    • ALGAE
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    • v.35 no.4
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    • pp.325-335
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    • 2020
  • A new diatom species, Mayamaea vietnamica sp. nov., is described from Cát Tiên National Park in Vietnam. This species was discovered and described from soil samples. Algae from soil ecosystems in Vietnam are almost unknown. The new species is described on the basis of an integrated approach with molecular and morphological data, and comparison with similar species. In terms of molecular data, 18S rDNA (including V4 domain), and partial rbcL plastid genes show M. vietnamica sp. nov. is most closely related to M. terrestris N. Abarca and R. Jahn, and together they form a monophyletic group relative to other members of the genus. M. vietnamica sp. nov. differs from other species in the genus by the number of striae and areolae in 10 ㎛, number of areolae per stria, as well as shape and presence or absence of axial and central areas.

A Study on Agricultural Product Warehouse Management based on Ontology (온톨로지기반 농수산물 창고관리에 관한 연구)

  • Kim, John;Lee, Hyun-Chang;Koh, Jin-Gwang
    • Journal of the Korea Society of Computer and Information
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    • v.14 no.9
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    • pp.205-210
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    • 2009
  • This paper proposes an ontology-based context aware system model for the purpose of storing and managing agricultural products using ubiquitous sensors to share and distribute information. In these days, according to penetrating ubiquitous technologies into our way of life, the importance of information is increasing gradually. The importance of ontology in a domain is getting as well. Therefore, this paper designs and build an ontology-based agricultural products warehouse model using context aware state information obtained by using wireless sensors. Also, it shows the result described by graphical ontology results to share common understanding on the structure of context information among users, devices and services to enable semantic interoperability owing to the information of the context aware state of the warehouse.

Comparative Modeling and Molecular Dynamics Simulation of Substrate Binding in Human Fatty Acid Synthase: Enoyl Reductase and β-Ketoacyl Reductase Catalytic Domains

  • John, Arun;Umashankar, Vetrivel;Krishnakumar, Subramanian;Deepa, Perinkulam Ravi
    • Genomics & Informatics
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    • v.13 no.1
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    • pp.15-24
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    • 2015
  • Fatty acid synthase (FASN, EC 2.3.1.85), is a multi-enzyme dimer complex that plays a critical role in lipogenesis. This lipogenic enzyme has gained importance beyond its physiological role due to its implications in several clinical conditions-cancers, obesity, and diabetes. This has made FASN an attractive pharmacological target. Here, we have attempted to predict the theoretical models for the human enoyl reductase (ER) and ${\beta}$-ketoacyl reductase (KR) domains based on the porcine FASN crystal structure, which was the structurally closest template available at the time of this study. Comparative modeling methods were used for studying the structure-function relationships. Different validation studies revealed the predicted structures to be highly plausible. The respective substrates of ER and KR domains-namely, trans-butenoyl and ${\beta}$-ketobutyryl-were computationally docked into active sites using Glide in order to understand the probable binding mode. The molecular dynamics simulations of the apo and holo states of ER and KR showed stable backbone root mean square deviation trajectories with minimal deviation. Ramachandran plot analysis showed 96.0% of residues in the most favorable region for ER and 90.3% for the KR domain, respectively. Thus, the predicted models yielded significant insights into the substrate binding modes of the ER and KR catalytic domains and will aid in identifying novel chemical inhibitors of human FASN that target these domains.

Correlation of Occupational Stress Index with 24-hour Urine Cortisol and Serum DHEA Sulfate among City Bus Drivers: A Cross-sectional Study

  • Du, Chung-Li;Lin, Mia Chihya;Lu, Luo;Tai, John Jen
    • Safety and Health at Work
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    • v.2 no.2
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    • pp.169-175
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    • 2011
  • Objectives: The questionnaire of occupational stress index (OSI) has been popular in the workplace, and it has been tailored for bus drivers in Taiwan. Nevertheless, its outcomes for participants are based on self-evaluations, thus validation by their physiological stress biomarker is warranted and this is the main goal of this study. Methods: A cross-sectional study of sixty-three city bus drivers and fifty-four supporting staffs for comparison was conducted. Questionnaire surveys, 24-hour urine cortisol testing, and blood draws for dehydroepiandrosterone-sulfate (DHEA-S) testing were performed. The measured concentrations of these biological measures were logarithmically transformed before the statistical analysis where various scores of stressor factors, moderators, and stress effects of each OSI domain were analyzed by applying multiple linear regression models. Results: For drivers, the elevated 24-hour urine cortisol level was associated with a worker's relationship with their supervisor and any life change events in the most recent 3 months. The DHEA-S level was higher in drivers of younger age as well as drivers with more concerns relating to their salary and bonuses. Non-drivers showed no association between any stressor or satisfaction and urine cortisol and blood DHEA-S levels. Conclusion: Measurements of biomarkers may offer additional stress evaluations with OSI questionnaires for bus drivers. Increased DHEA-S and cortisol levels may result from stressors like income security. Prevention efforts towards occupational stress and life events and health promotional efforts for aged driver were important anti-stress remedies.

Full-Length Infectious Clones of Two New Isolates of Tomato Mosaic Virus Induce Distinct Symptoms Associated with Two Differential Amino Acid Residues in 128-kDa Protein

  • Choi, Go-Woon;Oh, June-Pyo;Cho, In-Sook;Ju, Hye-Kyoung;Hu, Wen-Xing;Kim, Boram;Seo, Eun-Young;Park, Jong-Seok;Domier, Leslie L;Hammond, John;Song, Kihak;Lim, Hyoun-Sub
    • The Plant Pathology Journal
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    • v.35 no.5
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    • pp.538-542
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    • 2019
  • In 2017, two new tomato mosaic virus (ToMV) isolates were collected from greenhouses in Buyeo, Chungcheongnam-do, South Korea. Full-length cDNAs of the new ToMV isolates were cloned into dual cauliflower mosaic virus 35S and T7 promoter-driven vectors, sequenced and their pathogenicities investigated. The nucleotide sequences of isolates GW1 (MH507165) and GW2 (MH507166) were 99% identical, resulting in only two amino acid differences in nonconserved region II and the helicase domain, Ile668Thr and Val834Ile. The two isolates were most closely related to a ToMV isolate from Taiwan (KJ207374). Isolate GW1 (Ile668, Val834) induced a systemic hypersensitive response in Nicotiana benthamiana compared with the isolate GW2, which a single residue substitution showed was due to Val834.

Calvin's Reformation in Geneva and the Urban Missional Direction of Christianity Today (도시 제네바에서의 칼빈의 종교개혁과 현대 기독교의 도시 선교적 방향성 모색)

  • Bong, Won Young
    • The Journal of the Korea Contents Association
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    • v.21 no.11
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    • pp.436-449
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    • 2021
  • The purpose of this study is to examine the characteristics of the Reformation Calvin undertook in Geneva and see what efficient functions Christianity can afford to reveal its value in urban settings today. Calvin's Reformation provided a clear place and role for the Church in the public domain. In addition, Calvin's process of religious reform has always been followed by interest and welfare practices for the socially disadvantaged, such as the poor and women. In this understanding, the study presented the following applications that modern churches can practice in urban settings today: First, the church should be able to clearly understand the diversity, liquidity, and dynamics of the urban environment and make changes through various situational applications supported by the Bible. Second, the church's missional approach should shift from a believing-belonging process to a sense of belonging-believing. Third, the transition from a familiar traditional church to a new social reality is necessary, and efforts are needed to clearly understand the interests and atmosphere of community communities and keep pace with them. And finally, modern churches need to maintain new ecological sensitivity than ever before.