• Computers and Concrete
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• 제8권5호
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• pp.563-581
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• 2011

The signal-based acoustic emission (AE) characterization of concrete fracture process utilizing home-programmed AE monitoring system was performed for three kinds of static loading tests (Cubic-splitting, Direct-shear and Pull-out). Each test was carried out to induce a distinct fracture mode of concrete. Apart from monitoring and recording the corresponding fracture process of concrete, various methods were utilized to distinguish the characteristics of detected AE waveform to interpret the information of fracture behavior of AE sources (i.e. micro-cracks of concrete). Further, more signal-based characters of AE in different stages were analyzed and compared in this study. This research focused on the relationship between AE signal characteristics and fracture processes of concrete. Thereafter, the mode of concrete fracture could be represented in terms of AE signal characteristics. By using cement-based piezoelectric composite sensors, the AE signals could be detected and collected with better sensitivity and minimized waveform distortion, which made the characterization of AE during concrete fracture process feasible. The continuous wavelet analysis technique was employed to analyze the wave-front of AE and figure out the frequency region of the P-wave & S-wave. Defined RA (rising amplitude), AF (average frequency) and P-wave & S-wave importance index were also introduced to study the characters of AE from concrete fracture. It was found that the characters of AE signals detected during monitoring could be used as an indication of the cracking behavior of concrete.

• Nutrition Research and Practice
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• 제10권4호
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• pp.456-463
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• 2016

BACKGROUND/OBJECTIVES: Setting healthful beverage expectations, making calcium-rich foods and beverages (CRF/B) available, and role modeling are parenting practices promoting calcium intake among early adolescents. This study aimed to evaluate emotion-based messages designed to motivate parents of early adolescents to perform these practices. SUBJECTS/METHODS: Emotion-based messages were developed for each parenting practice and tested in 35 parents from 5 states. Findings were used to modify messages and develop a survey administered via Amazon MechanicalTurk to a convenience sample of Asian (n = 166) and Hispanic (n = 184) parents of children 10-13 years. Main outcome measures were message comprehension, motivation, relevance, acceptability, and novelty. Engagement in the parenting practices was also assessed. RESULTS: Message comprehension was acceptable for the majority of parents. Most also agreed that messages were motivational (setting healthful beverage expectations (69.0%), making CRF/B available (67.4%), and role modeling (80.0%)), relevant and acceptable. About 30-50% indicated they had not seen the information before. Many parents indicated they were already engaging in the practices (> 70%). No racial/ethnic differences were observed for responses to messages or engaging in parenting practices. CONCLUSIONS: Results indicate that emotion-based messages designed to motivate parents to engage in parenting practices that promote calcium intake among early adolescents were motivating, relevant, and acceptable.

• Journal of Microbiology and Biotechnology
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• 제21권5호
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• pp.483-493
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• 2011

An acid phosphatase (HppA) activated by $NH_4Cl$ was purified 192- and 34-fold from the periplasmic and membrane fractions of Helicobacter pylori, respectively. SDS-polyacrylamide gel electrophoresis revealed that HppA from the latter appears to be several kilodaltons larger in molecular mass than from the former by about 24 kDa. Under acidic conditions (pH${\leq}$4.5), the enzyme activity was entirely dependent on the presence of certain mono- and/or divalent metal cations (e.g., $K^+$,$ NH_4{^+}$, and/or $Ni^{2+}$). In particular, $Ni^{2+}$ appeared to lower the enzyme's $K_m$ for the substrates, without changing $V_{max}$. The purified enzyme showed differential specificity against nucleotide substrates with pH; for example, the enzyme hydrolyzed adenosine nucleotides more rapidly at pH 5.5 than at pH 6.0, and vice versa for CTP or TTP. Analyses of the enzyme's N-terminal sequence and of an $HppA^-$ H. pylori mutant revealed that the purified enzyme is identical to rHppA, a cloned H. pylori class C acid phosphatase, and shown to be the sole bacterial 5'-nucleotidase uniquely activated by $NH_4Cl$. In contrast to wild type, $HppA^-$ H. pylori cells grew more slowly. Strikingly, they imported $Mg^{2+}$ at a markedly lowered rate, but assimilated urea rapidly, with a subsequent increase in extracellular pH. Moreover, mutant cells were much more sensitive to extracellular potassium ions, as well as to metronidazole, omeprazole, or thiophenol, with considerably lowered MIC values, than wild-type cells. From these data, we suggest that the role of the acid phosphatase HppA in H. pylori may extend beyond 5'-nucleotidase function to include cation-flux as well as pH regulation on the cell envelope.

• Journal of Ginseng Research
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• 제44권6호
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• pp.775-783
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• 2020

Background: The reports about valuable oligosaccharides in ginseng are quite limited. There is an urgent need to develop a practical procedure to detect and analyze ginseng oligosaccharides. Methods: The oligosaccharide extracts from ginseng were permethylated by solid-phase methylation method and then were analyzed by ultra-high-performance liquid chromatography-Q-Orbitrap/MS. The sequence, linkage, and configuration information of oligosaccharides were determined by using accurate m/z value and tandem mass information. Several standard references were used to further confirm the identification. The oligosaccharide composition in white ginseng and red ginseng was compared using a multivariate statistical analysis method. Results: The nonreducing oligosaccharide erlose among 12 oligosaccharides identified was reported for the first time in ginseng. In the comparison of the oligosaccharide extracts from white ginseng and red ginseng, a clear separation was observed in the partial least squares-discriminate analysis score plot, indicating the sugar differences in these two kinds of ginseng samples. The glycans with variable importance in the projection value large than 1.0 were considered to contribute most to the classification. The contents of oligosaccharides in red ginseng were lower than those in white ginseng, and the contents of maltose, maltotriose, maltotetraose, maltopentaose, maltohexaose, maltoheptaose, maltooctaose, maltononaose, sucrose, and erlose decreased significantly (p < 0.05) in red ginseng. Conclusion: A solid-phase methylation method combined with liquid chromatography-tandem mass spectrometry was successfully applied to analyze the oligosaccharides in ginseng extracts, which provides the possibility for holistic evaluation of ginseng oligosaccharides. The comparison of oligosaccharide composition of white ginseng and red ginseng could help understand the differences in pharmacological activities between these two kinds of ginseng samples from the perspective of glycans.

• Asian Pacific Journal of Cancer Prevention
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• 제16권7호
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• pp.2909-2914
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• 2015

Objective: To investigate the protective effect of quercetin on radiation induced lung injury (RILI) and related mechanisms. Materials and Methods: Mice treated with radiation and/or quercetin were sacrificed at 1-8 weeks after irradiation under anesthesia. Lung tissues were collected for histological examination. Immunohistochemistry (IHC) and Western blotting were performed to detect the protein expression of nuclear factor-${\kappa}B$ ($NF-{\kappa}B$) and Mitogen-activated protein kinases (MAPK) pathway. Results: Hematoxylin and eosin (HE) staining showed that radiation controls displayed more severe lung damage than quercetin groups, either high or low dose. Results of IHC and Western blotting demonstrated the expression level of $NF-{\kappa}B$ to be decreased and that of an inhibitor of $NF-{\kappa}B$ ($I{\kappa}b-{\alpha}$) to be increased by the quercetin intervention compared with the radiation control group. Numbers of JNK/SAPK, p38 and p44/p42 positive inflammatory cells were decreased in the radiation+quercetin injection group (P<0.05). Conclusions: Quercetin may play a radio-protective role in mice lung via suppression of $NF-{\kappa}B$ and MAPK pathways.

• 한국주거학회논문집
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• 제11권3호
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• pp.43-51
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• 2000

This study aims to find the characteristics of the folk houses in the upper area of Seomjin river in the view point of generating housing floor plans by their human and natural elements of environment. Because they are formed differently as them and have the characteristics as the houses in the upper area of Seomjin river. Seomjin river flows from mid-west area of the Korean peninsula to the southern sea. This is about 212.3km long and the fourth in the south of the Korean peninsula. It is surrounded high mountains in the upper area and makes open field in the mid and lower area of river. The study is surveyed and analyzed to the folk houses of the middle and lower class people in the area of Seomjin river. Because they have been formed by their natural and human elements of environment gradually. They are 35 houses - 13 in Jinan-kun, 4 in Imsil-kun, 10 in Namwon city, 10 in Sunchang-kun. They are analyzed by their floor plans and their spatial relations. The result of this study is that they are made by their natural and human elements of environment. There are some houses with semi-several wings and with storage that are appeared in the mountain village. It reflects that they are surrounded by high mountains. And there are some houses with wooden floor room that are appeared in the area of river little in the area of mountain. To prevent wind from the river the houses are layouted as a form . open ㄴ type, open ㄷ type, and their wall is made of stone and planted bamboo trees around their houses.

• 대한토목학회논문집
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• 제31권1B호
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• pp.1-11
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• 2011

DEM을 이용한 수로망의 생성은 수문해석모형의 적용을 위한 전처리 과정으로써 실제 유역시스템의 배수구조를 결정하는 중요한 인자로 활용된다. 본 연구에서는 DEM으로부터 합리적인 수로망 추출과정 수립을 목적으로 보편적으로 사용되고 있는 면적한계기준과 국부경사와 기여면적사이의 특성에 근거한 경사-면적한계기준 기법을 이용하여 수로망을 생성하고 지형법칙에 의거하여 각 기법에 따른 소규모 유역(진안천 유역; $18.28km^2$) 배수구조의 신뢰성을 평가하였다. 그 결과, 면적한계 기준 기법은 수원유역의 크기의 인위적 결정에 의해 지형법칙을 만족시키지 못하고 유역전체의 배수구조를 왜곡되게 묘사한 반면, 경사-면적한계기준 기법의 경우 물리적인 지형법칙을 만족시키는 우수한 결과를 나타냈다. 따라서 경사-면적한계기준 기법은 DEM 기반의 수문모형을 적용 시 효율적이고 객관적인 수로망 생성을 위한 방법론으로서 활용이 가능하리라 판단된다.

• Archives of Plastic Surgery
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• 제44권2호
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• pp.136-143
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• 2017

Background The goal of this study was to investigate the anatomy of the peroneal artery and its perforators, and to report the clinical results of reconstruction with peroneal artery perforator flaps. Methods The authors dissected 4 cadaver legs and investigated the distribution, course, origin, number, type, and length of the perforators. Peroneal artery perforator flap surgery was performed on 29 patients. Results We identified 19 perforators in 4 legs. The mean number of perforators was 4.8 per leg, and the mean length was 4.8 cm. Five perforators were found proximally, 9 medially, and 5 distally. We found 12 true septocutaneous perforators and 7 musculocutaneous perforators. Four emerged from the posterior tibia artery, and 15 were from the peroneal artery. The peroneal artery perforator flap was used in 29 patients. Retrograde island peroneal flaps were used in 8 cases, anterograde island peroneal flaps in 5 cases, and free peroneal flaps in 16 cases. The mean age was 59.9 years, and the defect size ranged from $2.0cm{\times}4.5cm$ to $8.0cm{\times}8.0cm$. All the flaps survived. Five flaps developed partial skin necrosis. In 2 cases, a split-thickness skin graft was performed, and the other 3 cases were treated without any additional procedures. Conclusions The peroneal artery perforator flap is a good alternative for the reconstruction of soft tissue defects, with a constant and reliable vascular pedicle, thin and pliable skin, and the possibility of creating a composite tissue flap.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제12권10호
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• pp.4738-4753
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• 2018

Efficient rendezvous node selection and routing algorithm (RNSRA) for wireless sensor networks with mobile sink that visits rendezvous node to gather data from sensor nodes is proposed. In order to plan an optimal moving tour for mobile sink and avoid energy hole problem, we develop the RNSRA to find optimal rendezvous nodes (RN) for the mobile sink to visit. The RNSRA can select the set of RNs to act as store points for the mobile sink, and search for the optimal multi-hop path between source nodes and rendezvous node, so that the rendezvous node could gather information from sensor nodes periodically. Fitness function with several factors is calculated to find suitable RNs from sensor nodes, and the artificial bee colony optimization algorithm (ABC) is used to optimize the selection of optimal multi-hop path, in order to forward data to the nearest RN. Therefore the energy consumption of sensor nodes is minimized and balanced. Our method is validated by extensive simulations and illustrates the novel capability for maintaining the network robustness against sink moving problem, the results show that the RNSRA could reduce energy consumption by 6% and increase network lifetime by 5% as comparing with several existing algorithms.

• Geomechanics and Engineering
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• 제19권6호
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• pp.485-498
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• 2019

Pre-tensioned rock bolts can be classified into fully anchored, lengthening anchored and point anchored bolts based on the bond length of the resin or cement mortar inside the borehole. Bolts in varying anchoring methods may significantly affect the supporting effect of surrounding rock around a tunnel. However, thus far, the theoretical basis of selecting a proper anchoring method has not been thoroughly investigated. Based on this problem, 16 schemes were designed while incorporating the effects of anchoring length, pretension, bolt length, and spacing, and a systematic numerical experiment was performed in this paper. The distribution characteristics of the stress field in the surrounding rock, which corresponded to various anchoring scenarios, were obtained. Furthermore, an analytical approach for computing the active and passive strengthening index of the anchored surrounding rock is presented. A new fully anchoring method with pretension and matching technology are also provided. Then, an isolated loading model of the anchored surrounding rock was constructed. The physical simulation test for the bearing capacity of the model was performed with three schemes. Finally, the strengthening mechanism of varying anchoring methods was validated. The research findings in this paper may provide theoretical guidelines for the design and construction of bolting support in tunnels.