• 한국자원식물학회:학술대회논문집
• /
• 한국자원식물학회 2020년도 추계국제학술대회
• /
• pp.73-73
• /
• 2020

Toona sinensis (TS) leaf is known to antinociceptive, antioxidative stress and skin moisturizing effects. Acnes vulgaris is a chronic skin disease with various symptoms including itchiness, pain and interruption of normal skin function. Propionibacterium acnes (P. acnes) is a major factor in the occurrence of inflammatory acnes. This study evaluated the antioxidant and anti-inflammation effects by TS extract from adventitious shoots. TS extract showed anti-inflammatory activities by suppression of pro-inflammation mediators (iNOS and COX-2) in LPS-stimulated RAW264.7 cells. TS extract also has anti-inflammatory activities by inhibiting the secretion of pro-inflammatory cytokines on P. acnes-stimulated HaCaT cells. These effects were regulated by MAPK signaling pathway. Therefore, we suggest that TS extract from adventitious shoots might have applications as a medicine for treating P. acnes-induced skin diseases.

• 전력전자학회논문지
• /
• 제24권6호
• /
• pp.438-444
• /
• 2019

In this paper, bidirectional LLC resonant DC/DC converters with the primary auxiliary windings in transformers of resonant circuits are proposed. Although the resonant capacitors are used on both the primary and secondary sides, regardless of the direction of power flow, the main feature of the proposed converters exhibits high gain characteristics without any mutual coupling between the resonant capacitors. For one of the proposed converters, an investigation of the operating characteristics in each mode has been carried out. A prototype of a 3.3 kW bidirectional LLC resonant converter for interfacing 750 V DC buses has been built and tested to verify the validity and applicability of the proposed converter.

• 한국조리학회지
• /
• 제13권3호
• /
• pp.187-198
• /
• 2007

Some problems are presented that Korean restaurants in jeonju area don't keep ancient fame, taste and tradition. Therefore, this thesis intends to positively analyse the evaluation of Korean restaurants' menu quality to activate Han brand, centering on Jeonju area. The findings of the study are as follows: First, this thesis named the items of analysis menu quality factor, menu quality evaluation factor, Han brand activating factor. Second, it analysed confirmative factor of menu quality evaluation and found that conformity was $x^2=67.143$, df=14, GFI=0.968, AGFI=0.917, RMR=0.056, NFI=0.902, CFI=0.962. It means that the measure of item variables was selected appropriately. Third, it constructed a menu quality evaluation model of Korean restaurants in Jeonju area and verified hypotheses, such as menu quality factors and their influences on menu quality evaluation, menu quality evaluation factors and their influences on activating of Han brand, and menu quality factors and their influences on activating Han brand. It verified the relations, and, as a result, found them to be positive(+) and selected all of the hypotheses.

• 전력전자학회논문지
• /
• 제22권6호
• /
• pp.517-526
• /
• 2017

In this paper, we propose an LLC resonant converter that operates over a wide controllable output voltage ($50V_{DC}$ to $800V_{DC}$) and shows high efficiency characteristics under all load conditions and output voltages. Two 3.3kW prototypes are designed for an experimental comparison between the variable frequency control (control scheme 1) and the variable input voltage($V_{IN}$) control (control scheme 2) mechanisms. The experimental results show that the variable input control mechanism demonstrates high efficiency under all loads and output voltages.

• 전력전자학회논문지
• /
• 제25권1호
• /
• pp.44-53
• /
• 2020

A bridgeless single-stage AC-DC converter for wireless power charging systems is proposed. This converter is composed of a PFC stage and a three-level hybrid DC-DC stage. The proposed converter can control the wide output voltage (200-450 V_DC) by the variable link voltage and the pulse-width voltage applied to the primary resonant circuit due to the phase-shifted modulation at a fixed switching frequency. Moreover, the input power factor and the total harmonic distortion can be improved by using the proposed converter. A 1 kW prototype was fabricated and validated through experimental results and analysis.

• 전력전자학회논문지
• /
• 제23권6호
• /
• pp.424-432
• /
• 2018

This study presents a single-phase single-stage three-level AC/DC converter with a wide controllable output voltage. The proposed AC/DC converter is designed to extend the application of e-mobility, such as electric vehicles. The single-stage converter integrates a PFC converter and a three-level DC/DC converter, operates at a fixed frequency, and provides a wide controllable output voltage (approximately 200-430Vdc) with high efficiencies over a wide load range. In addition, the input boost inductors operate in a discontinuous mode to improve the input power factor. The switching devices operate with ZVS, and the converter's THD is small, especially at full load. The feasibility of the proposed converter is verified by the experimental results of a 1.5 kW prototype.

• 전력전자학회논문지
• /
• 제27권6호
• /
• pp.515-525
• /
• 2022

The wireless power transfer (WPT) charging system for AGV depends highly on the coupling conditions due to air gap variation. To attain stable output power with high transfer efficiency under various coupling conditions, a single-stage, DC-DC converter that operates with robustness to changes in air gaps is proposed for the WPT system. The proposed converter is capable of soft switching under the set input voltage (V_in: 380 V_DC), load conditions (0-1 kW), and air gap changes (30-70 mm). In addition, a wide output voltage range (Vo: 39-54 V_DC) can be controlled by varying the link voltage due to the phase control at a fixed switching frequency. Experimental results are verified using a prototype of a 1 kW wireless power charging system.

• 동의생리병리학회지
• /
• 제21권1호
• /
• pp.333-337
• /
• 2007

Cellulitis is a infectious disease characterized by acute purulent inflammation clinically manifested by erythema, pain or heating sensation caused by palpation, chilling sign and mild to moderate fever. in western medicine most part of the treatment is focused on injecting routine antibiotics hoping for the pathogen(in the case bacteria) to be treated but instead causing the bacteria to be resistant to antibiotics and consequently leads to longer admission. In oriental medicine Cellulitis belongs to the cathegory of Ong(癰), Bal(發) or Dandok(丹毒) on symptoms. The chief cause of acute Cellulitis is the evil of wet and heat blended and the postraumatic infection evil. We experienced a case of acute cellulitis defined as Bicheonbal(비천발) and Chokbaebal(足背發). We attempted to use both methods using acupuncture, herbal medicine(Gamidangkwuijeomtong-tang(加味當歸拈痛湯)) as well as routine antibiotic treatment and as a result we have achieved remarkable results in laboratory tests though there was no difference in shortening the curing process compared to the average time that it take to cure when admitted to western medical center.

• 생약학회지
• /
• 제44권2호
• /
• pp.110-117
• /
• 2013

Cirsium japonicum (CJ) leaf (L) alcoholic extracts were investigated for analysis their active components (flavonoids and flavanolignans; silymarins) and inhibitory effect on transforming growth factor (TGF)-${\beta}$ induced hepatic stellate cells (HSCs, LX-2 cells) activation. The CJ root (R) extracts were also analyzed and compared with leaf extracts. Total flavonoid and polyphenol contents of the leaf extracts showed higher than those of the root extracts. The content of each flavonoid compound, which was analyzed by HPLC, in CJ-L extracts was also higher than in CJ-R extracts. The results of flavanolignans content in CJ-L and CJ-R extracts were consistent in flavonoid and polyphenol. We studied inhibitory effect of two extracts against TGF-${\beta}1$ induced HSCs activation. The CJ-L extracts significantly suppressed overexpression of profibrogenic factor, ${\alpha}$-smooth muscle actin and collagen-${\alpha}1$(I). The CJ-R extract also showed inhibitory effect on TGF-${\beta}1$ induced HSCs activation, but the efficacy was lower than in CJ-L extract. These results suggest that CJ-L may contribute to the fibrotic liver treatment.

• Preventive Nutrition and Food Science
• /
• 제17권1호
• /
• pp.14-21
• /
• 2012

The purpose of this study was to investigate the anti-allergy activities of persimmon leaf extract (PLE) on a phthalic anhydride (PA)-induced allergic mouse model. A human leukemic mast cell line (HMC-1) was used to examine the inhibitory activity of PLE on the histamine release by human leukemic mast cells. PLE inhibited histamine release from HMC-1 cells in response to cross-linkage of high-affinity IgE receptor-${\alpha}$ ($Fc{\varepsilon}RI{\alpha}$). Additionally, a PA-induced allergic mouse model was used to investigate the effects of PLE in vivo. Mice were orally administrated with or without PLE of single dose (250 mg/kg/day) for 31 days. Oral intake of PLE significantly inhibited passive cutaneous reactions. Oral administration of PLE to PA-induced allergic mice also led to a striking suppression of the development of contact dermatitis, ear swelling and lymph node weight. In addition, PA-specific IL-4 production of draining lymph node cells was markedly diminished by PLE oral administration, but not IFN-${\gamma}$. Furthermore, PLE treatment suppressed PA-induced thymus and activation-regulated chemokine (CCL17) and cutaneous T cell-attracting chemokine (CCL27) expressions in ear tissues. Based on these results, we suggest that PLE may have therapeutic potential as an effective material for management of irritant contact dermatitis or related inflammatory diseases.