• 마이크로전자및패키징학회지
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• 제26권4호
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• pp.69-74
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• 2019

PMN-PT 단결정 시편의 유전 및 압전 특성의 측정 결과에 미치는 측정 기구물의 영향을 고찰하였다. 샘플에 교류 전기신호를 인가하는 지그핀의 압력이 감소할수록 공진저항은 낮게 측정되고 기계적 품질계수는 높게 계산되었다. 지그핀의 스프링 텐션이 20 grf인 경우 기계적 품질계수는 418으로 측정되었고, 스프링 텐션이 200 grf인 경우 품질계수 값은 절반으로 감소하였다. 4-프로브 방식의 픽스쳐는 압전특성 측정에는 부적합하지만 유전손실 값의 측정에는 가장 적합하였다. 정확한 PMN-PT의 압전특성 평가를 위하여 지그핀의 스프링 텐션을 최대한 낮추는 것이 필요하며, 정확한 유전특성의 평가를 위하여 4-프로브 방식이 적합함을 알 수 있다.

• 한국물환경학회지
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• 제32권2호
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• pp.149-162
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• 2016

In recent years, there has been demand for precise estimations of pollutant loads on nationwide scale for the development of appropriate site specific (watershed specific) policies to reduce the negative impact of pollutant loads. River flow data and water quality data that were previously collected by various research institutes and universities for specific research purposes for a limited period was utilized in this study. However, only TMDL 8-day interval flow and water quality data were available in national scale. Three watersheds were selected and pollutant loads were calculated by two methods i.e., Numeric Integration (NI) method and Soil and Water Assessment Tool (SWAT). Subsequently, the results were compared to determine the appropriate method for monitoring nonpoint source networks nationwide. The SWAT model was calibrated and its estimated daily flow data were used in the NI method with estimated sediment data for 8-day monitoring data for three watersheds. The results indicated that the quantity of pollutant loads estimated with the NI and SWAT are different to some degrees especially during the summer season for all the three study watersheds. Thus, more frequent sampling of water quality is needed for nonpoint source pollutant estimation.

• 대한유전성대사질환학회지
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• 제13권2호
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• pp.104-110
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• 2013

Purpose: Phenylketonuria (PKU) is the first inherited metabolic disease of which treatment is known. We performed this study to find out clinical symptoms and prognosis of tetrahydrobiopterin (BH4) responsive PKU patients and genetic relation. Methods: Clinical, biochemical, genetic analysis were done retrospectively in 23 patients diagnosed BH4 responsive PKU in Soonchunhyang University Hospital from March 2000 to September 2012. Results: Patients were classified to mild hyperphenylalaninemia and mild phenylketonuria with initial plasma phenylalanine level below 20 mg/dL. After BH4 loading, blood phenylalanine decrease level ranged between 37% and 99%. Initial treatment with low phenylalanine formula or BH4 was started before 2 month after birth except 2 patients. And one of them resulted in developmental delay in language and social activity. The others showed satisfactory progress without developmental delay. In genetic analysis, of 46 allele, R241C allele mutation was identified most commonly (41%). R241C/A259T, R241C/R243Q, R241C/V388M, R241C/T278I was detected in 5 (21.7%), 3 (13%), 2 (8%), 2 (8%) patients, respectively. Conclusion: R241C mutation was detected most frequently in this study group and R243Q mutation which is known to be prevalent in Korean PKU patients was found in 4 patients (8.6%). Early diagnosis and treatment is important in PKU patients.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2019년도 학술발표회
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• pp.325-325
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• 2019

본 연구에서는 안동댐 유역을 대상으로 Soil and Water Assessment Tool(SWAT) 모형을 이용해 하천단면 특성을 고려하여 유량 및 수질(SS, TN, DO)을 모의하였다. 안동댐 유역 내 위치한 도산 및 안동댐 관측소의 실측 유량 자료를 이용하였으며, 낙본B 관측소의 수질 측정 자료를 이용하였다. 본 연구에서는 항공사진을 통해서 안동댐 유역 내 각각의 소유역에 대하여 평균 하천폭과 홍수터폭 자료를 구축하였으며, 이를 실측 자료로 가정하였다. 또한 하천단면 실측 자료를 기반으로 상류 유역 면적에 대한 하천폭 및 홍수터폭 회귀식을 개발하였다. 이렇게 개발된 회귀식을 통해 산정된 하천폭과 홍수터폭을 SWAT 모형에 적용하여 유량 및 수질 모의를 모의하였으며, 하천단면 특성을 고려하기 이전(Scenario 1, S1)과 이후(Scenario 2, S2)의 모의 결과를 비교하여 하천단면 특성 고려에 따른 모의 결과의 차이에 대하여 분석하였다. S1와 S2의 하천폭과 홍수터폭을 비교한 결과 S1이 하천폭과 홍수터폭을 과대 산정하는 것으로 나타났으며, S1의 유속은 S2보다 작게 나타났다. 유량 모의 결과와 실측 자료에 대한 $R^2$와 NSE를 산정한 결과 S1과 S2의 결과는 큰 차이를 나타내지 않았으나, S2가 S1에 비해 상대적으로 첨두유량을 높게 모의하는 경향이 나타났다. 유량 모의 결과와 달리 수질 모의 결과에서는 S1과 S2의 차이가 뚜렷하게 나타났다. SS, TN, DO 모의 결과 모두에서 S2가 S1보다 높은 모의 정확도를 나타내었다. 결론적으로 하천단면 특성이 유량 및 수질 모의 정확도에 영향을 주는 것으로 나타났으며, 특히 하천단면과 관련한 변수들은 수질 모의에 있어서 민감하게 영향을 주는 것으로 판단되었다. 하지만 본 연구는 단일 유역에 대해서만 진행되었기 때문에 연구 결과의 신뢰성을 확보하기 위해서는 본 연구의 연구대상 유역과 다른 유역 특성을 가진 유역들을 대상으로 본 연구의 결과에 대한 재검토가 필요하다.

• 한국농공학회논문집
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• 제61권4호
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• pp.33-42
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• 2019

In this study, the channel and floodplain widths are indirectly measured for three different watersheds using satellite images to reflect the shape of Korean channels in the Soil and Water Assessment Tool (SWAT) model. For measuring the channel and floodplain widths, multiple satellite images were referred to ensure the widest width of certain points. In the single channel, the widths at the multiple points were measured. Based on the measured data, the regression equations were derived to estimate the channel and floodplain widths according to watershed areas. Applying these developed equations, this study evaluated the effect of the change of channel and floodplain widths on the SWAT simulation by comparing to the measured streamflow data. The developed equations estimated larger channel width and smaller floodplain compared with those calculated in the current SWAT model. As shown in the results, there was no considerable changes in the predicted streamflow using the current and developed equations. However, the flow velocity and channel depth calculated from the developed equations were smaller than those of the current equations. The differences were caused by the effect of different channel geometries used for calculating the hydraulic characteristics. The channel geometries also affected the water quality simulation in channels because the hydraulic characteristics calculated by the channel geometries are directly related to the water quality simulation. Therefore, application of the river cross-sectional regression equation reflecting the domestic stream shape is necessary for accurate water quantity / quality and water ecosystem simulation using hydrological model.

• Journal of Genetic Medicine
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• 제15권2호
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• pp.92-96
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• 2018

Chronic mucocutaneous candidiasis (CMC) is characterized by increased susceptibility to chronic and recurrent infections of the skin, mucous membranes, and nails by Candida species. It is a primary immunodeficiency disorder that is difficult to diagnose because of its heterogeneous clinical manifestations and genetic background. A 20-month-old boy who did not grow in height for 3 months was diagnosed as having hypothyroidism and he had hepatitis which was found at 5 years old. He presented with persistent oral thrush and vesicles on the body, the cause of which could not be identified from laboratory findings. No microorganism was detected in the throat culture; however, the oral thrush persisted. Immunological tests showed that immunoglobulin (Ig) subclass IgG and cluster of differentiation (CD)3, CD4, and CD8 levels were within normal limits. We prescribed oral levothyroxine and fluconazole mouth rinse. The patient was examined using diagnostic exome sequencing at the age of 6 years, and a c.1162A>G (p.K388E) STAT1 gene mutation was identified. A diagnosis of CMC based on the STAT1 gene mutation was, thus, made. At the age of 8 years, the boy developed a malar-like rash on his face. We conducted tests for detection of antinuclear antibodies and anti-dsDNA antibodies, which showed positive results; therefore, systemic lupus erythematosus (SLE) was also suspected. Whole exome sequencing is important to diagnose rare diseases in children. A STAT1 gene mutation should be suspected in patients with chronic fungal infections with a thyroid disease and/or SLE.

• Parasites, Hosts and Diseases
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• 제57권3호
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• pp.299-302
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• 2019

A clonorchiasis case in a captive leopard cat, Prionailurus bengalensis euptilurus, was confirmed by ultrasonographic findings and egg morphologies found in the bile juice sample in the Korea. The leopard cat was introduced from the wild habitat of Gyeongsangnam-do, to Cheongju Zoo in Cheongju-si, Chungcheongbuk-do, Korea in August 2014. Physical examinations were basically performed for quarantine and check-up health. The cat was comparatively good in health except anorexia. The cyst-like bile duct dilation and the increased echogenicity of gall bladder wall and hepatic parenchyma were observed by ultrasonography. Ultrasound-guided needle biopsy was conducted for collecting bile juice and the specimens were observed under light microscope. The numerous small trematode eggs were detected in the bile juice sample of the light microscopy. The eggs were $25-33(28{\pm}3){\mu}m$ by $18-22(20{\pm}1){\mu}m$ in size and showed typical characteristics of Clonorchis sinensis egg, i.e., a dominantly developed operculum, shoulder rim and dust-like wrinkles in surface. To treat the liver fluke infection, 20 mg/kg of praziquantel was orally administered only once to the case. Follow-up studies including fecal examinations were conducted during 2 years after treatment. But no more eggs were detected from the case. In the present study, we described the first clonorchiasis case of leopard cat, which was confirmed by ultrasonographic findings and egg morphologies from the bile juice sample in Korea.

• 한국농공학회논문집
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• 제61권2호
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• pp.25-39
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• 2019

The water pollution Accident in the South Han River is increasing due to increase of pollutants inflow from small streams from rural areas and reduced flow rate. This study predicted the change of water quality in the main stream of the South Han River due to climate change through the linkage of watershed and water quality models. Also, This study analyzed the effect of water quality improvement on Seomgang and the South Han River by securing the flow during the dry season. According to the scenarios for securing the river flow during drought season, the river flow in the Seomgang is increased up to 2.19 times, and the water quality during the drought season was improved up to $BOD_5$ 20.5%, T-N 40.8%, T-P 53.4%. Also, the water quality of the main stream of the South Han River improved to 5.22% of $BOD_5$, 5.42% of T-N and 7.69% of T-P as the river flow was secured from the Seomgang. The result of this study confirms that securing the baseflow in the Seomgang according to the scenarios for securing the river flow during the dry season has a positive effect on the improvement of the water quality of the rivers in the main river of the Seomgang and South Han River. The results of this study will contribute to the establishment of reasonable management to improve the water quality of the main stream of the Seomgang and South Han River.

• 한국정보기술학회논문지
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• 제17권4호
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• pp.109-117
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• 2019

현대 사회는 불특정 다수를 대상으로 자행되는 각종 사고와 범죄 위협으로 인하여 사회 전반에 걸쳐 개인의 보안 의식이 증가되며 다양한 감시 기법이 활발히 연구되고 있으나, 여전히 단순 부주의 또는 오작동으로 인한 강인성 저하가 발생하여 보다 높은 신뢰성을 갖는 감시 기법이 요구된다. 이에, 본 논문에서는 다양한 환경 및 동·정적 변화 감지에서의 낮은 강인성을 보완하고 비용 효율성 문제를 해결하기 위한 실시간 변화감지 기법을 제안한다. 변화 감지 구현을 위해 데이터 군집화 기법으로 응용되고 있는 자기 조직화 신경망을 활용하였으며, 실내 사무실 환경에서의 모의실험을 통해 기존 영상 감시 시스템에서 응용되는 감지 기법 대비 뛰어난 잡음 강인성과 이상 감지 판단의 우수성을 확인할 수 있었다.

• 한국물환경학회지
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• 제37권3호
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• pp.175-189
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• 2021

In this study, 48 streams in the Sapgyo Watershed were selected, and the Load Duration Curves (LDC) were drawn up for each stream using water quality and flow monitoring over the last three years (2018-2020), and it was evaluated whether the target water quality was achieved for each flow section. As a result of evaluating whether or not the target water quality exceeded according to the LDC, it was found that 22 rivers exceeded the target water quality. Five rivers exceeded the target water quality due to point pollutant sources, 13 rivers exceeded the target water quality due to non-point pollutant sources, and 4 rivers exceeded the target water quality due to both point and non-point pollutant sources. Among the rivers that exceeded the target water quality due to point pollutant sources, which included domestic sewage of the untreated population, there is a need to reduce the influx of polluted loads by the untreated population. The use of eco-friendly fertilizers is recommended for rivers with a relatively high farmland ratio among rivers exceeding the target water quality due to non-point pollutant sources, and installation of boiling point reduction facilities that can reduce the amount of polluted load introduced during rainfall or manage water shores. In rivers with a large number of livestock breeding heads, the livestock houses located in these rivers need to be preferentially transferred to livestock manure treatment plants. Due to the high ratio of land area because of urbanization, initial rainwater treatment facilities are required to reduce the amount of pollutant load flowing into the river through the impermeable layer during rainfall.