• Journal of the Society of Cosmetic Scientists of Korea
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• v.30 no.3 s.47
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• pp.389-392
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• 2004

We screened several materials to stimulate IGF-1 promoter activity using luciferase reporter assay and found that Amomi Semen extract (ASE) among them is the most powerful stimulator We also studied about the anti-wrinkle effect of ethanolic extract of Amoni Semen in vitro and in vivo. Semi-quantitative RT-PCR showed that the extract elevated the presence level of IGF-1 mRNA. And $[^3H]$ proline incorporation and semi-quantitative RT-PCR showed that the extract increased the expression of type-I collagen compared with vehicle in vitro and in vivo, respectively. Significant inhibition of MMP-1 expression was determined by ELISA and Western blot. Finally, topical treatment of the extract on hairless mouse's dorsal skin expanded the volume of collagen and dermal thickness. These results suggest that Amomi Semen may be a good candidate for improving extracellular matrix through the increase of collagen expression and inhibition of MMP-1 expression. Moreover, this study enables us to guess that IGF-1 stimulated by the extract may be involved in the mechanism of anti-wrinkle effect of it.

• Food Science and Preservation
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• v.15 no.3
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• pp.361-366
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• 2008

This study was investigated the functional characteristic change by the enzymatic hydrolysate to improve the functionality of soybean milk. The soymilk (SM), hydrolysates of soy milk (HSM), whole soy milk (WSM) and hydrolysates of whole soy milk (HWSM) revealed composition difference whether the bean-curd removal was included or not, but nearly no change was found by the low molecule enzyme treatment. The chromaticity revealed clear difference whether the bean-curd was removed or not, but did not show any difference by the hydrolyzation. Total free sugar and oligosaccharide content was found to be 1,389.88 mg% in SM, 1,013.51 mg% in HSM, 1,539.51 mg% in WSM, and 1,331.53 mg% in HWSM by showing the reduction after the enzyme hydrolyzation. DPPH free radical scavenging activity revealed to show high activity in HSM and in HWSM which were enzymatically hydrolyzed by 49.26% and 45.34%, respectively. And the ACE inhibition activity of HSM and HWSM was found to be approximately 1.6 times higher than the control SM and HSM The superoxide radical scavenging activity revealed to show high activity at HSM and HWSM, and no difference was found by the removal of bean-curd from raw soybean. Based upon these results, the functional characteristics of HSM, WSM and HWSM were found to be excellent compared to SM and it is expected to be used as various functional sources in a future.

• Korean Journal of Environment and Ecology
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• v.30 no.5
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• pp.821-828
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• 2016

We examed physiological and flowering response of S. capitata, the endangered plant in Korea, under LED light conditions in plant factory to cultivate artificially for conservation. We cultivated S. capitata and measured its physiological responses and the number of flowers under red, blue, white, red+far-red mixed, red+blue mixed, and red+blue+white mixed light. The results showed that its photosynthetic rate and chlorophyll content were recorded relatively high in red+blue+white and red+blue mixed light respectively. Transpiration rate and stomatal conductance appeared relatively high in the white single light while water use efficiency was no difference. Photochemical efficiency of photochemical photosystem II by minimum and maximum chlorophyll fluorescence was the highest in the red+blue+white mixed light condition than other ones. The number of flowers of S. capitata was at its peak under the red light or red+far-red mixed light. Therefore, we conclude that the most efficient way to grow for flowering of S. capitata is to provide red light or red+far-red mixed light in the plant factory.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.44 no.5
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• pp.70-75
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• 2007

A dual-frequency dual-polarization (DFDP) antenna with high isolation between two ports by embedding $2{\times}1$ mushroom-like electromagnetic bandgap (EBG) cells is proposed. The equivalent circuit of a suspended microstrip line over $2{\times}1$ EBG cells is introduced. The numerical analysis from the equivalent circuit and measured results show that the microstrip line with embedded EBG cells has a distinctive and sharp rejection band and provides near 0 dB insertion loss outside the rejection band. By embedding the EBG cells under feedlines of a conventional DFDP antenna, the isolation between two ports of the antenna is enhanced more than 20 dB, as compared to that of a conventional DFDP antenna. The proposed DFDP antenna is fabricated and measured. The simulated and measured results show a good agreement. The measured polarization purity and gain of the antenna are 25 dB and 5.77 dBi at lower band, and 35 dB and 7.13 dBi at higher band, respectively.

• The Journal of Korea Assosiation for Disability and Oral Health
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• v.12 no.2
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• pp.96-100
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• 2016

Metachromatic leukodystrophy (MLD) is a progressive and degenerative neurological disease caused by a deficiency of the catabolic enzyme arylsulfatase A. Deficiency of arylsulfatase A results in accumulation of sulfatide in the white matter of the peripheral and central nervous system and it occurs demyelination as a result. The patient gradually goes through mental and motor failure. General symptoms of MLD include gait disturbance, mental deterioration, muscle rigidity and impaired swallowing. Inheritance of the disease is autosomal recessive. We report a dental caries treatment of a 3-year old boy with MLD. The patient underwent hematopoietic stem cell transplantation (HSCT) to slow the progression of the disease. He was suffered from difficulties of mastication and swallowing from the degenerative neurological symptom. He was ingesting food by both oral feeding and tubal feeding after he took percutaneous endoscopic gastrostomy (PEG). The cause of multiple caries was mainly presumed as patient's prolonged time of meal. The treatment was performed under general anesthesia considering patient's incompliance. Severely affected lower primary molars were treated with pulp treatment and restored with stainless steel crown. Others were restored with composite resin. There were no postoperative complications. MLD is life threatening progressive disease and also has an impact on unfavorable condition for oral health. Routine home oral care and periodic professional dental care should be emphasized to the caregiver of patient considering the susceptibility of dental caries. Not only the medical care, but periodic dental office visit would benefit the quality of life of the patient.

• The Journal of Korea Assosiation for Disability and Oral Health
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• v.12 no.2
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• pp.77-81
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• 2016

The Dandy-Walker syndrome is a relatively rare congenital malformation occurring about one in 25,000-35,000 pregnancies. It is characterized by hydrocephalus, cystic dilatation of the fourth ventricle, complete or partial absence of the cerebellar vermis, and other various extra-CNS malformations. We report a dental caries treatment of a 4-year old girl with Dandy-Walker syndrome and partial trisomy 9q. The patient visited Seoul National University Dental Hospital due to multiple caries. The cause of multiple caries is mainly presumed as patient's eating habit caused by her general condition. She was still using milk bottle because she was having difficulties swallowing solid food due to breathing problem while eating. The treatment was performed under general anesthesia considering patient's condition; delayed development, very poor cooperation and respiratory problem. The dental procedure was successfully conducted and there were no postoperative complications. In consideration of her eating habit and oral hygiene problem, regular check appointment was recommended.

• The Journal of Korea Assosiation for Disability and Oral Health
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• v.12 no.2
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• pp.82-86
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• 2016

Lowe syndrome is X-linked gene disorder, characterized by cataracts, renal dysfunction and brain abnormalities. Oral healthcare of young patients with Lowe syndrome could be easily neglected due to the uncooperative behavior or other systemic condition of the child. We are presenting a case of successful treatment under general anesthesia with uncooperative child with Lowe syndrome. A 3-year old boy with Lowe syndrome visited Seoul National University Dental Hospital for multiple caries. He had been suffering from congenital cataract, medullary nephrocalcinosis and hypotonia. Multiple caries were observed from clinical and radiographic examination. Concerning behavior management problem and possibility of aspiration due to hypotonia, dental treatment under general anesthesia was planned. Left upper primary first molar was extracted to prevent further infection. Other teeth were treated with Stainless steel crown or composite resin restoration based upon the extent and the severity of dental caries. Under general anesthesia, dental procedure was carried out successfully and safely. Considering uncooperative behavior and other medical conditions of the patient, general anesthesia could be effective. Home oral care and periodic visit to dental clinic should be emphasized to the caregiver of patient with Lowe syndrome, considering the susceptibility of dental caries and other oral manifestation.

• The Journal of Korea Assosiation for Disability and Oral Health
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• v.12 no.2
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• pp.87-91
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• 2016

Pierre Robin syndrome (PRS) is characterized by the triad of congenital mandibular hypoplasia, glossoptosis and cleft palate. Infant PRS patients are frequently suffering from upper airway obstruction, gastroesophageal reflux and growth retardation caused by above mentioned problems. We report a dental caries treatment of 3-year old girl with Pierre Robin syndrome with multiple caries. The cause of multiple caries was mainly presumed as patient's eating habit caused by her general condition. She had some feeding problems and had history of gastric tube. She was still using milk bottle and took more than an hour to finish a meal. The treatment was performed under general anesthesia considering patient's condition; mild autism, poor cooperation and respiratory problem due to micrognathia. Severely affected upper incisors were treated with pulp treatment and restored with zirconia crown for esthetic purpose. Lower incisors were treated with pulp treatment and restored with composite resin. Upper right first primary molar was restored with stainless steel crown and other primary molars were treated with composite resin. There were no postoperative complications. According to her parents, the patient's compliance to oral hygiene management was greatly improved after the treatment since she was very pleased with the esthetic result and highly motivated by her looks. The treatment without sedation or general anesthesia would be possible once the airway is improved as the mandible grows.

• Korean Journal of Soil Science and Fertilizer
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• v.46 no.1
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• pp.65-72
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• 2013

This study was carried out to understand the long-term effects of organic waste treatments on the fate of heavy metals in soils originated from the organic wastes and consequent uptake of heavy metals by plant, together with examination of changes in soil properties and plant growth performance. In this study, the soils treated with three different organic wastes (municipal sewage sludge, alcohol fermentation processing sludge, pig manure compost) at three different rates (12.5, 25.0, 50.0 ton $ha^{-1}yr^{-1}$) for 7 years (1994 - 2000) were used. To see the long-term effect, plant growth study and soil examination were conducted twice in 2000 and 2010, respectively. There was no additional treatments of organic wastes for 10 years after the organic waste treatment for 7 years. Compared to plant growth examination conducted in 2000 using radish (Raphanus sativus cv. sodamaltari), it appeared that height, root length and diameter, fresh weight of radish grown in 2010 decreased in the plots treated with municipal sewage sludge and alcohol fermentation processing sludge and that the extent of decrease was higher with increase of sludge application rates. On the other hand, pig compost treatment increased plant height, root length and diameter, fresh weight with increasing application rates. Cu and Pb concentrations in radish root and leaves increased in 2010 compared to those in 2000 while Ni concentrations in root and leaves decreased. Zn concentration was increased only in the soils treated with pig manure compost. Multiple regression analysis among heavy metal species fractions in soils, soil pH, and metal concentrations in radish root and leaves indicated that the metal uptake by radish was governed mainly by the soil pH and subsequent increase of available heavy metal fractions in soils with organic waste treatments.

• The Bulletin of The Korean Astronomical Society
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• v.37 no.2
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• pp.79.2-79.2
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• 2012

SN 2011fe (also known as PTF 11kly) is a Type-1a supernova that appeared in M101, 2011 August. Being only 6.4 Mpc away, this supernova has been intensively observed by various facilities in the world. We monitored this supernova in UBVRI, grizY, and ZYJHK-bands using SNUO, LOAO, SOAO, CQUEAN/McDonald, UKIRT telescopes, and small telescopes in Korea and Mongolia. The monitoring observation is still ongoing, and the light curve has been accumulated over a year. We present the results of the long-term monitoring observation, together with a light-curve fitting result. We will also discuss our findings in terms of the usefulness of Type-Ia supernovae as a distance indicator.