• Journal of Life Science
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• v.23 no.9
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• pp.1126-1132
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• 2013

Cytochrome P450 2J2 (CYP2J2) is an enzyme mainly found in human extrahepatic tissues, with predominant expression in the cardiovascular system. CYP2J2 plays important roles in the metabolism of endogenous metabolites and therapeutic drugs, such as arachidonic acid, astemizole, ebastine, and terfenadine. CYP2J2 is also overexpressed in human cancer tissues and cancer cell lines and may represent a potential target for therapy of human cancers. In this study, 10 natural products obtained from plants and microorganisms were screened as potential CYP2J2 inhibitors. Among them, thelephoric acid showed strong inhibition of astemizole O-demethylation activity ($IC_{50}=3.23{\mu}M$) in a dose-dependent manner. Evaluation of the substrate dependency of the inhibitory activity of thelephoric acid showed that it strongly inhibited CYP2J2-mediated ebastine hydroxylation ($IC_{50}=5.32{\mu}M$) and terfenadine hydroxylation ($IC_{50}=3.27{\mu}M$) in a substrate nondependent manner. The present data suggest that this compound might be a potential candidate for further evaluation for anticancer activity.

• Journal of the Korean Society for Industrial and Applied Mathematics
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• v.11 no.2
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• pp.9-14
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• 2007

A signed 3-partite graph is a 3-partite graph in which each edge is assigned a positive or a negative sign. Let G(U, V, W) be a signed 3-partite graph with $U\;=\;\{u_1,\;u_2,\;{\cdots},\;u_p\},\;V\;=\;\{v_1,\;v_2,\;{\cdots},\;v_q\}\;and\;W\;=\;\{w_1,\;w_2,\;{\cdots},\;w_r\}$. Then, signed degree of $u_i(v_j\;and\;w_k)$ is $sdeg(u_i)\;=\;d_i\;=\;d^+_i\;-\;d^-_i,\;1\;{\leq}\;i\;{\leq}\;p\;(sdeg(v_j)\;=\;e_j\;=\;e^+_j\;-\;e^-_j,\;1\;{\leq}\;j\;{\leq}q$ and $sdeg(w_k)\;=\;f_k\;=\;f^+_k\;-\;f^-_k,\;1\;{\leq}\;k\;{\leq}\;r)$ where $d^+_i(e^+_j\;and\;f^+_k)$ is the number of positive edges incident with $u_i(v_j\;and\;w_k)$ and $d^-_i(e^-_j\;and\;f^-_k)$ is the number of negative edges incident with $u_i(v_j\;and\;w_k)$. The sequences ${\alpha}\;=\;[d_1,\;d_2,\;{\cdots},\;d_p],\;{\beta}\;=\;[e_1,\;e_2,\;{\cdots},\;e_q]$ and ${\gamma}\;=\;[f_1,\;f_2,\;{\cdots},\;f_r]$ are called the signed degree sequences of G(U, V, W). In this paper, we characterize the signed degree sequences of signed 3-partite graphs.

• Asian Journal of Turfgrass Science
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• v.17 no.2_3
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• pp.75-80
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• 2003

Growth characteristics such as density(quality), covering speed, green period, disease resistance, heading existence(number of seeds) and other characteristics were examined for selection of superior lines among the 133 zoysiagrass lines collected in 2001. Six superior lines were selected and the results were summarized as follows. Superior line, J01067 was longest for green period among the 133 zoysiagrasses and stayed green until the beginning of November. Leaf width of J01106 and J01129 lines was very narrow as 1.5mm and 2mm, respectively and superior for density(quality), covering speed and disease resistance. J01122 line was selected for strongest disease resistance among the lines of Zoysia japonica. Leaf width of J01128 was 3.2mm showing midium type and similar to standard cultivar, Sunburst. This line also showed higher density and strong disease resistance like J01106 and J01129. Five growth characteristics for morphological classification of 133 zoysiagrass lines was used and divided into 3 cluster groups. Of 133 lines, 6 standard cultivars and 6 superior lines were classified as follows. First cluster group contained Belare, Meyer, Anyang-jungji, J01067, J01122, and second group contained S-94 and J01105, and third group contained Sunburst, Konhee, J01106, J01128 and J01129.

• Bulletin of the Korean Mathematical Society
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• v.50 no.6
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• pp.2061-2070
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• 2013

In this paper, we investigate the generalized HyersUlam-Rassias stability of the following additive functional equation $$2\sum_{j=1}^{n}f(\frac{x_j}{2}+\sum_{i=1,i{\neq}j}^{n}\;x_i)+\sum_{j=1}^{n}f(x_j)=2nf(\sum_{j=1}^{n}x_j)$$, in quasi-${\beta}$-normed spaces.

• 한국초전도학회:학술대회논문집
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• 2009.07a
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• pp.12-12
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• 2009

• Journal of Bio-Environment Control
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• v.31 no.4
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• pp.279-285
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• 2022

This study was carried out to establish proper irrigation standards by growth stages using integrated solar radiation (ISR) for strawberry hydroponics cultivation. The irrigation methods were automatically controlled when it reached ISR values based on the external solar irradiance. The ISR standards were set at 150 J·cm^-2 and 200 J·cm^-2, and as the last treatment, ISR value was changed from 200 J·cm^-2 to 150 J·cm^-2 according to growth stage. The timer-automated irrigation system was applied as a control. The monthly average irrigation frequency of 150 J·cm^-2, growth stages (150 J·cm^-2) treatment in March were 5.6 times, that of 200 J·cm^-2, growth stages (200 J·cm^-2) treatment in December were 2.7 times, and that of timer system was 3.6-3.8 times. The water use efficiency (WUE) of timer was 19.8 g·L^-1 lower than ISR. There was no significant difference in growth and fruit characteristics between ISR and timer. The total yield and rate of marketable fruit of treatments by growth stages was the highest 328 g/10 a and 85.3 %, respectively. Therefore, in case of strawberry hydroponic cultivation, controlling ISR by growth stages was more helpful to improve yield rather than applying same ISR standard during cultivation.

• Proceedings of the Korean Information Science Society Conference
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• 2000.10a
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• pp.466-468
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• 2000

J2EE(JavaTM 2 Platform, Enterprise Edition)의 클라이언트 애플리케이션, 웹 컴포넌트, Enterprise JavaBeans 컴포넌트와 같은 앤터프라이즈 애플리케이션은 개발된 후 컨테이너에 배치되어 실행된다. 이러한 앤터프라이즈 애플리케이션(enterprise application)은 다양한 EIS(Enterprise Information System)에 접근하여 관련된 기능과 데이터를 사용할 필요가 있다. J2EE 커넥터 아키텍처(Connector Architecture)는 J2EE 플랫폼을 다양한 EIS와 연결하기 위한 표준을 정의하는 API 이며, 각 EIS 벤더는 이러한 커넥터 아키텍처의 설계서를 따르는 EISF의 시스템 레벨 소프트웨어 드라이버인 표준 리소스 어댑터(Resource Adaptor)를 제공한다. 커넥터 아키텍처를 구현한 리소스 어댑터를 사용함으로써 특정 벤더의 J2EE 플랫폼에 종속되지 않도록 EIS를 통합할 수 있다. 본 논문에서는 이러한 J2EE 커넥터 아키텍처를 구현한 리소스 어댑터를 애플리케이션 서버를 배치하기 위하여 배치기가 수행해야 하는 배치 단계를 크게 네 단계로 구분하고, 배치구성 활동을 다섯 가지로 분류 및 정의한다,

• Proceedings of the SCSK Conference
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• 1992.09a
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• pp.36-45
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• 1992

The dosal sites of 61 Koreans were exposed to increasing UVB doses in the 10mJ/$\textrm{cm}^2$ interval from 10mJ/$\textrm{cm}^2$ to 100mJ/$\textrm{cm}^2$ by solar-simulator, and at the 24hr after UV-B exposure we determined the first MED (Minimal Erythema Dose). For the precise measurements, we peformed the second exposures arround the first MED with 2.5mJ/$\textrm{cm}^2$ interval. The mean MED of all volunteers was 39.6 $\pm$ 15.7mJ/$\textrm{cm}^2$. As the distinction of sex, the means of male and female were 46.9 $\pm$ 18.1mJ/$\textrm{cm}^2$ and 31.5$\pm$8.5mJ/$\textrm{cm}^2$ respectively. According to the classification of skin type by Greiter. F.(1), the percent of skin type I to Ⅵ were 10.9%, 36.4%, 34.6%, 12.7%, 3.6%, and 1.8% respectively.

• Journal of Korea Society of Industrial Information Systems
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• v.12 no.2
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• pp.1-15
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• 2007

The purpose of this study is to design and develop a mobile game using J2ME, which is currently the most popular choice for game development to understand the process of mobile game development and to develop methods that address weaknesses of J2ME. The development was done with the Eclipse IDE(Integrated Development Environment) tool to simplify mobile game development by removing the need for complex commands and installation processes which are intrinsic to the DOS command Batch file arid J2ME Wireless Toolkit when used for the implementation of java mobile games. Literature was also reviewed on mobile game environments, the structures of J2ME Platform, and past research on mobile games, to investigate which parts of J2ME are important to the characteristics of mobile game development and how to implement these important parts when developing.

• Journal of Oral Medicine and Pain
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• v.24 no.4
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• pp.397-410
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• 1999

In order to obtain the basic data concerning the optimal parameters in using Nd:YAG laser as a therapeutic modality to dentinal hypersensitivity, the author prepared 3 sections of sound dentin and 10 sections of sclerotic dentin with thickness of $0.5mm{\pm}0.1mm$ from human extracted teeth of anteriors and premolars, and applied the laser energy from a fiberoptic delivered, free running, pulsed Nd:YAG laser (wavelength 1064nm, pulse duration $120{\mu}sec$, fiber diameter $320{\mu}m$) to surfaces of sound and sclerotic dentin sections for 1 second with contact/unidirectional moving mode of the fiber under speed of 3mm~4mm/sec and parameters of 0.5W/10Hz, 1.0W/10Hz, 1.5W/10Hz, 2.0W/10Hz: $62J/cm^2$, $124J/cm^2$, $187J/cm^2$, $249J/cm^2$. The author comparatively evaluated the characteristics of ultrastructural changes on surfaces of sound and sclerotic dentin sections irradiated by the pulsed Nd:YAG laser using the scanning electron microscopy. A fairly ill-defined bordered surface of partially closed and melted dentinal tubules can be seen on the scanning electron microscopic feature of the sound dentin surface irradiated by the pulsed Nd:YAG laser with energy density of $62J/cm^2$. The physical modification of sound dentin surface extensively occurred depended on the increase of energy density from $62J/cm^2$ to $124J/cm^2$, $187J/cm^2$, $249J/cm^2$. While, a fairly well-defined bordered surface of partially closed and melted dentinal tubules with thickened peritubular dentin can be seen on the scanning electron microscopic feature of the sclerotic dentin surface irradiated by the pulsed Nd:YAG laser with energy density of $62J/cm^2$. The physical modification of sclerotic dentin surface of a fairly rough, shallow depression with many cracks, thickened peritubular dentin and structureless dentinal tubules extensively occurred depended on the increase of energy density from $62J/cm^2$ to $124J/cm^2$, $187J/cm^2$, $249J/cm^2$ compared to those of sound dentin surface irradiated by the pulsed Nd:YAG laser under the same parameters. Therefore, it is recommended that the pulsed Nd:YAG laser as a therapeutic modality to dentinal hypersensitivity should be applied with the less energy density than $62J/cm^2$ on the sound dentin surface, and its energy density on the partially sclerotic dentin surface should be lower than that on the sound dentin surface to preserve tooth from unnecessary excessive structural destruction.