• Parasites, Hosts and Diseases
• /
• v.52 no.2
• /
• pp.143-149
• /
• 2014

To evaluate the seroprevalence against circumsporozoite protein (CSP) of Plasmodium vivax in sera of Korean patients, the central repeating domain (CRD) of CSP was cloned and analyzed. From the genomic DNA of patient's blood, 2 kinds of CSPs were identified to belong to a VK210 type, which is the dominant repeating of GDRA(D/A)GQPA, and named as PvCSPA and PvCSPB. Recombinantly expressed his-tagged PvCSPA or PvCSPB in Escherichia coli reacted well against sera of patients in western blot, with the detecting rate of 47.9% (58/121), which included 15 cases positive for PvCSPA, 6 cases positive for PvCSPB, and 37 cases for both. The mixture of PvCSPA and PvCSPB was loaded to a rapid diagnostic test kit (RDT) and applied with the same set of patient sera, which resulted in detection rates of 57.0% (69/121). When the protein sequences of PvCSPA were compared with those of P. vivax in endemic regions of India and Uganda, they were compatibly homologous to PvCSPA with minor mutations. These results suggested that the recombinant PvCSPA and PvCSPB loaded RDT may be a milestone in latent diagnosis which has been a hot issue of domestic malaria and important for radical therapy in overlapped infections with P. falciparum in tropical and subtropical areas. During the biological process of malarial infection, exposure of CSP to antigen-antibody reaction up to 57.0% is the first report in Korea.

• KSII Transactions on Internet and Information Systems (TIIS)
• /
• v.12 no.4
• /
• pp.1553-1571
• /
• 2018

Currently, many of schemes for smart grid data aggregation are based on a one-level gateway (GW) topology. Since the data aggregation granularity in this topology is too single, the control center (CC) is unable to obtain more fine-grained data aggregation results for better monitoring smart grid. To improve this issue, Shen et al. propose an efficient privacy-preserving cube-data aggregation scheme in which the system model consists of two-level GW. However, a risk exists in their scheme that attacker could forge the signature by using leaked signing keys. In this paper, we propose a secure and fine-grained electricity consumption aggregation scheme for smart grid, which employs the homomorphic encryption to implement privacy-preserving aggregation of users' electricity consumption in the two-level GW smart grid. In our scheme, CC can achieve a flexible electricity regulation by obtaining data aggregation results of various granularities. In addition, our scheme uses the forward-secure signature with backward-secure detection (FSBD) technique to ensure the forward-backward secrecy of the signing keys. Security analysis and experimental results demonstrate that the proposed scheme can achieve forward-backward security of user's electricity consumption signature. Compared with related schemes, our scheme is more secure and efficient.

• Journal of the Korea Institute of Information Security & Cryptology
• /
• v.27 no.4
• /
• pp.775-783
• /
• 2017

As interest in cloud computing grows, the number of users using cloud computing services is increasing. However, cloud computing technology has been steadily challenged by security concerns. Therefore, various security breaches are springing up to enhance the system security for cloud services users. In particular, research on detection of malicious VM (Virtual Machine) is actively underway through the introspecting virtual machines on the cloud platform. However, memory analysis technology is not used as a monitoring tool in the environments where multiple virtual machines are run on a single server platform due to obstructive monitoring overhead. As a remedy to the challenging issue, we proposes a computationally efficient instance memory introspection scheme to minimize the overhead that occurs in memory dump and monitor it through a partial memory monitoring based on the well-defined kernel memory map library.

• Proceedings of the Korean Vacuum Society Conference
• /
• 2016.02a
• /
• pp.378.2-378.2
• /
• 2016

Biosensors currently suffer from severe non-specific adsorption of proteins, which causes false positive errors in detection through overestimation of the affinity value. Overcoming this technical issue motivates our research. Polyethylene glycol (PEG) is well known for its ability to reduce the adsorption of biomolecules; hence, it is widely used in various areas of medicine and other biological fields. Likewise, amine functionalized surfaces are widely used for biochemical analysis, drug delivery, medical diagnostics and high throughput screening such as biochips. As a result, many coating techniques have been introduced, one of which is plasma polymerization - a powerful coating method due to its uniformity, homogeneity, mechanical and chemical stability, and excellent adhesion to any substrate. In our previous works, we successfully fabricated plasmapolymerized PEG (PP-PEG) films [1] and amine functionalized films [2] using the plasma enhanced chemical vapor deposition (PECVD) technique. In this research, an amine functionalized PP-PEG film was fabricated by using the plasma co-polymerization technique with PEG 200 and ethylenediamine (EDA) as co-precursors. A biocompatible amine functionalized film was surface characterized by X-ray photoelectron spectroscopy (XPS) and Fourier-transform infrared spectroscopy (FT-IR). The density of the surface amine functional groups was carried out by quantitative analysis using UV-visible spectroscopy. We found through surface plasmon resonance (SPR) analysis that non-specific protein adsorption was drastically reduced on amine functionalized PP-PEG films. Our functionalized PP-PEG films show considerable potential for biotechnological applications such as biosensors.

• Journal of the Korea Society of Computer and Information
• /
• v.20 no.3
• /
• pp.47-56
• /
• 2015

Automated detection of interesting web pages could be used in many different application domains. Determining a user's interesting web pages can be performed implicitly by observing the user's behavior. The task of distinguishing interesting web pages belongs to a classification problem, and we choose white box learning methods (fixed effect logit regression and support vector machine) to test empirically. The result indicated that (1) fixed effect logit regression, fixed effect SVMs with both polynomial and radial basis kernels showed higher performance than the linear kernel model, (2) a personalization is a critical issue for improving the performance of a model, (3) when asking a user explicit grading of web pages, the scale could be as simple as yes/no answer, (4) every second the duration in a web page increases, the ratio of the probability to be interesting increased 1.004 times, but the number of scrollbar clicks (p=0.56) and the number of mouse clicks (p=0.36) did not have statistically significant relations with the interest.

• Environmental Analysis Health and Toxicology
• /
• v.17 no.2
• /
• pp.147-160
• /
• 2002

Volatile organic compounds (VOCs) are an important public health issue in Korea and many important questions remain to be addressed with respect to assessing exposure to these compounds. Because they are ubiquitous and highly volatile, special techniques must be applied in their analytic determination Valid Personal exposure assessment methods are needed to evaluate exposure frequency, duration and intensity, as well as their relationship to personal exposure characteristics. Biological monitoring is also important since it may contribute significantly in risk assessment by allowing the estimation of effective absorbed doses. This study was on ducted to establish the environmental measurement, personal dosimetry and biological monitoring methods for VOCs. These methods are needed to compare blood, urinary and exhalation breath VOC levels and to provide tools for risk assessment of VOC exposure. Passive monitors (badge type) and a active samplers (trap) for the VOCs collection were used for air sampling. Methods development included determining the minimum detectable amounts of VOCs in each media, as well as evaluating collection methods and developing analytical procedures. Method reliability was assessed by determining breakthrough volumes and comparing results between laboratories and with other methods. A total capacity of trap used in this study was 60ι. Although variable by compound, the average breakthrough was 20％. Also, there was no loss of compounds in trap even if keep for 45 day in -7$0^{\circ}C$. The recovery of active and passive methods was 69％ ~ 126％ and method detection limit was 0.24 $\mu\textrm{g}$/trap and 0.07 $\mu\textrm{g}$/badge. There was no statistical difference (P > 0.05) between active and passive methods.

• Journal of Korea Association of Health Promotion
• /
• v.4 no.1
• /
• pp.85-94
• /
• 2006

Background Cardiovascular disease is becoming an important national health issue since its recent increase in incidence and mortality. The study was conducted to find out the prevalence of metabolic syndrome according to the clinical identification criteria by NCEP-ATP3 and Asia-Pacific criteria. Meterials & Methods: The subjects were 759 people -male 375 and female 384 after twenties age - who had undergone medical examinations at Korea Association of Health, Daejeon- Chungnam Branch. The prevalence of metabolic syndrome was assessed as defined by the NCEP ATP3, while abdominal obesity was assessed according to the Asia-Pacific guidelines. Anthropometric variables and cardiovascular risk factors were measured, and Associated factors with metabolic syndroms was analyzed by logistic regression analysis. Results The prevalence of metabotic syndrome was 24.O% for male and 27.1% for female The high blood pressure was the highest prevalent risk factors of metabolic syndrome. In the age group of thirties, the prevalence of metabolic syndrome was higher in men than in women, however it was significantly higher in women than in men in fifties and six ties. The metabolic syndrome was more prevalent in aged people over 50 years. and .significantly associated with BMI index(odds ratio 2.58 in male, 9.87 in female)Conclusions The prevalence of metabolic syndrome is over 20%.Early detection and intervention of risk factors by health examination and promotion are needed for prevention of metabolic syndrome.

• Journal of Korean Academy of Nursing
• /
• v.39 no.5
• /
• pp.741-750
• /
• 2009

Purpose: The purpose of this study was to identify the prevalence of cognitive impairment, behavioral problems, and the state of mental health for elderly Korean people who have been institutionalized. Methods: A cross-sectional, nationwide survey was performed using an anonymous questionnaire. The participants in this study were 2,521 institutionalized elderly Korean people. A proportional stratified random sampling method was employed. Results: 1) Elders admitted to subacute hospitals and long term care (LTC) facilities showed a higher level of cognitive impairment compared to elders admitted to acute care hospitals. 2) Elders confined in LTC facilities showed a higher level of behavioral problems compared to elders in acute or subacute hospitals. 3) Elders admitted to subacute hospitals and LTC facilities showed more serious mental health problems, such as depression or suicidal ideation, compared to elders in acute care hospitals. Conclusion: The results of this study indicate that the severity of cognitive-behavioral or mental health problems do not match well with type of care setting. Therefore, health personnel working with elderly people should be provided guidance on detection and management of cognitive-behavioral and mental health problems. The necessity of a decision support system for eligibility and placement in long-term care is also discussed.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
• /
• v.24 no.12
• /
• pp.1190-1197
• /
• 2013

AESA(Active Electronically Scanned Array radar) radar is able to instantaneously and adaptively position and control the beam, and such adaptive beam pointing of AESA radar enables to remarkably improve the multi-mission capability. For this reason, radar resource management(RRM) becomes new challenging issue. RRM is a technique efficiently allocating finite resources, such as energy and time to each task in an optimal and intelligent way. This paper deals with a design of radar resource management algorithms and simulator implemented main algorithms for development of airborne AESA radar. In addition, evaluation results show that developed radar system satisfies a main requirement about simultaneous multiple target tracking and detection by adopting proposed algorithms.

• Korean Journal of Construction Engineering and Management
• /
• v.13 no.3
• /
• pp.43-55
• /
• 2012

A methodology for BIM Quality Assurance in the construction industry is becoming increasingly an important issue to determine the reliability of BIM. However, the quality assurance of BIM is currently limited to check 3D models, such as clash detection and space layout while verification methods for disciplinary BIM results from structural engineering, mechanical engineering, and estimation do not exist yet. Particularly, in the BIM-based estimation mathematical equations to take off quantities are not clearly exposed so that the results are not quite accepted at practices. With the concept of reliability engineering defined in the manufacturing industry to improve reliability of outcomes of BIM-based quantity take-off, impacting factors that affect reliability of BIM-based quantity take-off were derived. It was found that the factors also include the modeling method and the features of a BIM tool. Therefore, this research aims to propose modeling and verification methods to improve reliability of BIM-based quantity take-off through the pilot test that was performed with commercial BIM tools and IFC-based BIM data.