• Nuclear Engineering and Technology
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• 제55권9호
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• pp.3291-3300
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• 2023

Recently molybdenum alloys have been introduced as accident tolerating materials for cladding of fuel rods. Molybdenum element has seven stable isotopes with different neutron absorption cross section used in various fields, including nuclear physics and radioisotope production. This study presents separation approaches for all intermediate isotopes of molybdenum element by squared-off cascades using a newly developed numerical code with Salp Swarm Algorithm (SSA) optimization algorithm. The parameters of cascade including feed flow rate, feed entry stage, cascade cut, input feed flow rate to gas centrifuges (GCs), and cut of the first stage are optimized to maximize both isotope recovery and cascade capacity. The squared off and squared cascades are studied, and the efficiencies are compared. The results obtained from the optimization showed that for the selected squared off cascade, Mo⁹⁴ in four separation steps, Mo⁹⁵ in five steps, Mo⁹⁶ in six steps, Mo⁹⁷ in seven steps, and Mo⁹⁸ in two steps are separated to the desired concentrations. The highest recovery factor is obtained 63% for Mo⁹⁴ separation and lowest recovery factor is found 45% for Mo⁹⁵.

• Nuclear Engineering and Technology
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• 제55권3호
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• pp.1036-1044
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• 2023

The combination of MCNP6 and the FISPACT codes was used to predict inventories of radioisotopes produced by neutron exposure of a sample in a research reactor. The detailed MCNP6 model of the Budapest Research Reactor and the specific irradiation geometry of the NAA channel was established, while realistic material cards were specified based on concentrations measured by PGAA and NAA, considering the precursor elements of all significant radioisotopes. The energy- and spatial distributions of the neutron field calculated by MCNP6 were transferred to FISPACT, and the resulting activities were validated against those measured using neutron-irradiated small and bulky targets. This approach is general enough to handle different target materials, shapes, and irradiation conditions. A general agreement within 10% has been achieved. Moreover, the method can also be made applicable to predict the activation properties of the near-vessel concrete of existing nuclear installations or assist in the optimal construction of new nuclear power plant units.

• 한국산림과학회지
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• 제102권1호
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• pp.129-135
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• 2013

낙엽송(Larix kaempferi) 채종원의 종자생산을 증진하기 위하여 접목 32년생의 채종목에 환상박피 처리를 하였다. 환상박피처리에 의하여 무처리보다 4배에 이르는 착과량 증가 효과가 있어 환상박피 처리의 효과가 뚜렷하게 나타났다. 환상박피 처리에 의한 낙엽송 주간 수피조직내의 대사물질의 변화를 IR-MS, GC-MS 및 HPLC로 분석하여 무처리와 비교한 결과 전질소 함량, sucrose 함량 및 전체 유리 아미노산의 함량이 무처리에 비해 유의적(p<0.05)으로 증가되었다. 또한 유리아미노산의 경우 화아원기가 형성되는 8월의 aspartic acid, glutamic acd, glycine, serine, cysteine, threonine 및 alanine이 환상박피 처리에서 무처리에 비해 유의적으로 높게 함유된 것으로 나타났다. 대사물질과 착과량간에 상관관계를 분석한 결과 착과량과 수피조직내의 전질소 함량(r=0.765, p<0.01)과 전체 유리 아미노산 함량(r=0.802, p<0.01)간에 고도의 정의 상관관계가 있었다. 특히, 화아원기 형성기인 7월 및 8월의 수피조직내의 aspartic acid, glutamic acd, glycine, serine 및 cysteine이 착과량과 정의 상관관계(p<0.05)가 있어, 아미노산의 질소화합물 인자가 낙엽송 화아원기 유도에 직, 간접적으로 관련이 있을 것으로 추정되었다.

• 지구물리와물리탐사
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• 제24권1호
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• pp.20-27
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• 2021

암석의 열생산율은 구성 광물 내 방사성 동위원소의 방사성 붕괴와 감마선 방출에 의한 열에너지에 기인하며, 그 크기는 주요 방사성 동위원소인 U, Th, K의 함량에 지배적이다. 그러므로 암반의 열생산율은 암석의 밀도와 주요 동위원소의 함량에 기반해 평가할 수 있다. 심부 암반의 열생산율 평가에 필요한 방사성 동위원소의 농도는 시추공에서 회수된 암추 또는 암편에 대한 질량분석을 통해 파악할 수 있는데, 대심도 시추공의 경우 요구되는 분석량과 그에 따른 시간 및 비용의 문제로 적용이 제한적일 수 밖에 없다. 시추공을 대상으로 하는 물리검층 중 암반의 감마선 스펙트럼으로부터 U, Th, K의 함량을 유추할 수 있는 기술이 있지만, 열생산율 평가를 위해 별개의 밀도검층 자료를 필요로 하며, 상용화된 장비의 적용 심도 또한 아직은 제한적이다. 이에 대한 대안으로 시추공 암반이 방출하는 감마선의 강도를 측정하는 자연 감마선 검층 결과로부터 열생산율을 유추하는 방법이 제안된 바 있으며, 국내외에서 비교적 쉽게 암반의 열생산율을 평가할 수 있는 방법으로 사용되고 있다. 본 기술보고에서는 국내 상용화된 대심도 시추공 물리검층 장비 및 기술을 활용해 감마선 검층 기반의 열생산율 평가 기법을 개발하고, 국내 약 2 km 깊이의 대심도 시추공에 대한 적용 및 검증 사례를 소개하고자 한다.

• Journal of Microbiology and Biotechnology
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• 제20권8호
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• pp.1196-1203
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• 2010

In the present work, methanethiol and dimethyldisulfide were investigated as sulfur sources for methionine synthesis in Corynebacterium glutamicum. In silico pathway analysis predicted a high methionine yield for these reduced compounds, provided that they could be utilized. Wild-type cells were able to grow on both methanethiol and dimethyldisulfide as sole sulfur sources. Isotope labeling studies with mutant strains, exhibiting targeted modification of methionine biosynthesis, gave detailed insight into the underlying pathways involved in the assimilation of methanethiol and dimethyldisulfide. Both sulfur compounds are incorporated as an entire molecule, adding the terminal S-$CH_3$ group to O-acetylhomoserine. In this reaction, methionine is directly formed. MetY (O-acetylhomoserine sulfhydrylase) was identified as the enzyme catalyzing the reaction. The deletion of metY resulted in methionine auxotrophic strains grown on methanethiol or dimethyldisulfide as sole sulfur sources. Plasmid-based overexpression of metY in the ${\Delta}$metY background restored the capacity to grow on methanethiol or dimethyldisulfide as sole sulfur sources. In vitro studies with the C. glutamicum wild type revealed a relatively low activity of MetY for methanethiol (63 mU/mg) and dimethyldisulfide (61 mU/mg). Overexpression of metY increased the in vitro activity to 1,780 mU/mg and was beneficial for methionine production, since the intracellular methionine pool was increased 2-fold in the engineered strain. This positive effect was limited by a depletion of the metY substrate O-acetylhomoserine, suggesting a need for further metabolic engineering targets towards competitive production strains.

• Journal of Plant Biotechnology
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• 제30권2호
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• pp.201-206
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• 2003

Differential responses of red pepper plant and cultured cells to enhanced ${\gamma}$-ray($^{60}$ Co) and ultraviolet(UV) stress were investigated. In seed treatment, 1 Gy of ${\gamma}$-ray increased seedling dry weight up to 19.1%, but 50 Gy treatment markedly ingibited seed germination and subsequent growth of seedling. UV treatment to seed did not change the germination ability of seeds and the growth of seedlings regardless of duration of UV treatment until 24 hrs. In case of UV treatment to seedlings, plant injury was seriously progressed even after the seedlings were returned to no UV condition, and eventually all the leaves showed chlorosis by the stress. However, progress of plant injury by ${\gamma}$-ray stress slower than that caused by UV stress, and even at the high dose of ${\gamma}$-ray 50 Gy, did not caused the cholrosis of stressed plant leaf. Amount of electrolytes leakage from plant leaf by UV treatment for 24hrs was increased up to 28.8 folds in comparison with untreated control, whereas that of 50 Gy of ${\gamma}$-ray was increased only 1.2 folds. UV stress induced the production of capsidiol, antimicrobial phytoalexin, by activation of gene expression involved in capsidiol biosynthesis, such as sesquiterpene cyclase and cyclase and cytochrome P450 hydroxylase in the leaf and cultured cell, but ${\gamma}$-ray stress induced neither the production of capsidiol nor expression of the genes.

• 자원환경지질
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• 제39권4호
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• pp.485-494
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• 2006

1920년대의 온천조사에서부터 현재에 이르기까지 우리나라 지열연구의 역사를 간략히 요약하고, 우리나라의 지열류량 연구 결과 및 추세, 지열의 근원 연구, 그리고 지열에너지 개발 및 활용분야에 대한 연구활동을 정리하였다. 우리나라에서의 지열연구는 1970년대까지 주로 온천조사와 관련되어 있다. 1980년대에 들어서 연구소와 학계에서 온천조사 뿐만 아니라, 지열류량에 대한 연구도 많이 수행하게 되었으며 1996년도에는 우리나라 전국적인 지온경사 분포도와 지열류량 분포도를 발간하게 되었다. 또한 우리나라 온천수에 대한 지화학적 동위원소 분석과 화강암 지대의 열생산율 측정도 1990년대에 주로 이루어졌다. 지열개발과 활용에 대한 시도는 1990년대 초반부터 시도되었으나 실제 개발을 위한 시추로 이어지게 된 것은 2000년대에 들어와서 가능해졌다. 최근의 활발한 심부 지열수 자원 개발이나 천부 지중열을 활용한 냉난방 수요의 증가 등 주변여건이 호전됨에 따라 우리나라 지열연구개발의 전망은 밝다고 판단된다.

• 방사선산업학회지
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• 제11권1호
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• pp.39-45
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• 2017

A cyclotron is a kind of particle accelerator that produces a beam of charged particles for the production of medical, industrial, and research radioisotopes. More than 30 cyclotrons are operated in Korea to produce $^{18}F$, an FDG synthesis at hospitals. A 30-MeV cyclotron was installed at ARTI (Advanced Radiation Technology Institute, KAERI) mainly for research regarding isotope production. In this study, we analyze and estimate the items of risk such as the problems in the main components of the cyclotron, the loss of radioactive materials, the leakage of coolant, and the malfunction of utilities, fires and earthquakes. To estimate the occurrence frequency in an accident risk assessment, five levels, i.e., Almost certain, Likely, Possible, Unlikely, and Rare, are applied. The accident consequence level is classified under four grades based on the annual permissible dose for radiation workers and the public in the nuclear safety law. The analysis of the accident effect is focused on the radioactive contamination caused by radioisotope leakage and radioactive material leakage of a ventilation filter due to a fire. To analyze the risks, Occupation Safety and Health Acts is applied. In addition, action plans against an accident were prepared after a deep discussion among relevant researchers. In this acts, we will search for hazard and introduce the risk assessment for the research 30-MeV cyclotron facilities of ARTI.

• 한국지구과학회지
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• 제43권5호
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• pp.569-578
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• 2022

백악기 중기, 세노마눔절-투로니아절에 발생한 해양 무산소 사건인 Oceanic Anoxic Event 2 (OAE2)는 다량의 유기물을 포함한 흑색셰일이 전세계적으로 퇴적된 단기간의 탄소 순환 교란 사건이다. 백악기 후기의 온실 지구의 환경(높은 CO₂농도, 고해수면, 해양의 무산소 환경 확장)은 탄소, 황 및 여타 주요 원소의 생지화학 순환의 교란과 밀접하게 상호 작용하였다. 1970년대 최초 명명 이후 동위원소를 포함한 화학적 지시자 연구가 활발하게 진행되었으며, 그 결과 화산 활동과 해양 표층의 유기물 생산 증가가 무산소 환경 발달의 주된 원인으로 여겨진다. 본 논평에서는 OAE2의 기작을 탄소 및 황, 미량 금속원소의 순환을 중심으로 살펴보고자 한다.

• Asian-Australasian Journal of Animal Sciences
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• 제20권4호
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• pp.536-542
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• 2007

The responses of whole body protein and glucose kinetics and of nitrogen (N) metabolism to non-protein energy intake (NPEI) were determined using an isotope dilution approach and measurement of N balance in three adult male goats. The diets containing 1.0, 1.5 and 2.0 times ME maintenance requirement, with fixed intake of CP (1.5 times maintenance) and percentage of hay (33%), were fed twice daily for each 21 d experimental period. After an adaptation period of 11 d, N balance was determined over 3 d. On day 17, whole body protein synthesis (WBPS) and glucose irreversible loss rate (ILR) were determined during the absorptive state by a primed-continuous infusion of [$^2H_5$]phenylalanine, [$^2H_2$]tyrosine, [$^2H_4$]tyrosine and [$^{13}C_6$]glucose, with simultaneous measurements of plasma concentrations of metabolites and insulin. Ruminal characteristics were also measured at 6 h after feeding over 3 d. Nitrogen retention tended to increase (p<0.10) with increasing NPEI, although digestible N decreased linearly (p<0.05). Increasing NPEI decreased (p<0.01) ammonia N concentration, but increased acetate (p<0.05) and propionate (p<0.05) concentrations in the rumen. Despite decreased plasma urea N concentration (p<0.01), increased plasma tyrosine concentration (p<0.05), and trends toward increased plasma total amino N (p<0.10) and phenylalanine concentrations (p<0.10) were found in response to increasing NPEI. Increasing NPEI increased ILR of both glucose (p<0.01) and phenylalanine (p<0.05), but did not affect ($p{\geq}0.10$) that of tyrosine. Whole body protein synthesis increased (p<0.05) in response to increasing NPEI, resulting from increased utilization rate for protein synthesis (p<0.05) and unchanged hydroxylation rate of phenylalanine ($p{\geq}0.10$). These results suggest that increasing NPEI may enhance WBPS and glucose turnover at the absorptive state and improve the efficiency of digestible N retention in goats, with possibly decreased ammonia and increased amino acid absorption. In addition, simultaneous increases in WBPS and glucose ILR suggest stimulatory effect of glucose availability on WBPS, especially when sufficient amino acid is supplied.