• Journal of Nutrition and Health
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• v.37 no.9
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• pp.794-800
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• 2004

Deer Antler has been known for its traditional oriental medicinal properties and has been widely used to promote growth, boost immune function, treat blood loss and chronic joint pain. Recent study showed imported (New Zealand) Deer Antler was beneficial in reducing the side effects of cancer treatments. However, there was no intervention study conducted on the effect of Korean Deer Antler on reducing the oxidative stress to patients with diabetes. One of the sensitive ways to measure endogenous oxidative stress is by measuring cellular DNA damage using single cell gel electrophoresis (COMET assay). This study was conducted to investigate the possible beneficial effect of commercial Deer Antler drink (provided by Chung-yang Deer Farm) on lymphocyte DNA damage and blood glucose of diabetic patients. Ten patients (4 men, 6 women) participated in the study and consumed 2 pouches of Deer Antler drink every day for 20 days. Blood was collected on the morning before and after the intervention for lymphocyte isolation and blood glucose analysis. Both systolic and diastolic blood pressure showed a tendency to decrease but did not reach statistical significance after the trial. Blood glucose level was not affected by the supplementation. After the intervention, over 50% reduction were noted in the cellular DNA damage, expressed as tail length (TL) and tail moment (TM: tail length ${\times}$ percent tail DNA) . Although we did not obtain beneficial effect on lowering blood glucose levels in the patients, this results suggest that Deer Antler may initially act in protecting endogenous DNA damage in short-term experiment.

• Journal of Environmental Science International
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• v.17 no.1
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• pp.113-118
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• 2008

[ $6{\sim}13mg/L$ ] base water concentration on monthly BOD has been kept at the Geukrak bridge point for this research target and it indicates the water quality under the existed rank. Due to this present condition of water quality, the demage of ecology from the upper stream to the lower one of the bridge could be conjectured. Moreover, nonstructural extinction of the ecology seems to have gotten worse between both the streams of Yeoungsan River. On this research, eco-corridor between the upper stream and the lower stream of the river should be ensured, the ecological demage needs to be cut off, a dispersed discharge method which the existed method of the 1st sewage plant in Gwangju was enhanced to should be inducted for the procuring of various water ecosystem, and the conditions by the scenario suggested from this research could be applied to a water quality model. then, analysis the improvement effect of the water quality adjacent the river. From the test result, Case3-Type1 scenario is thought to be the best one. From the test result with Case3-Type1 when the concentrated discharge was never done, 0.07 mg/L of BOD concentration was increased at the lower stream where Yeoungbon B point (Haksan Bridge) is but the water improvement effect of $0.24{\sim}2.87mg/L$ is thought to have been done at the area of water deterioration.

• Journal of the Korean Society of Food Science and Nutrition
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• v.33 no.9
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• pp.1419-1425
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• 2004

This study was performed to examine in vitro antioxidative activities such as DPPH radical scavenging activity, reducing power and tyrosinase inhibitory effect of various solvent fractions from Chionanthus retusa leaves. Ethyl acetate fraction showed potent antioxidative activity and tyrosinase inhibitory effect. The active compound was isolated from the butanol fraction by silica gel column chromatography and MPLC. The isolated compound was luteolin-4'-O-glucoside determined by $^1H$, $^{13}C$-NMR and 2D NMR. Compared with several antioxidant compounds, luteolin-4'-O-glucoside exhibited effective DPPH radical scavenging activity and reducing power in a concentration dependent manner. Bioassay with pure luteolin-4'-O-glucoside showed a dose-independent inhibitory effect on L-DOPA oxidation by mushroom tyrosinase and its $IC_{50}$ values were established as 23.2 ${\mu}g/mL$. Therefore, we may suggest that luteolin-4'-O-glucoside can be used as a food additive possessing the potent antioxidative activity and skin-whitening cosmetic material.

• KSBB Journal
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• v.18 no.4
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• pp.324-328
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• 2003

In a mutagenicity test using the Salmonella typhimurium TA98 and TA100, the Xanthium strumarium L. extracts had not a mutagenicity. The extracts were assayed that antioxidative effect using a colony formation assay. The extracts showed protective effects against the cytotoxicity of H$_2$O$_2$ and increased the immunity induced by TNF and IL-1${\beta}$. The modulating effect of Xanthium strumarium L. extract on the induction of carcinogenesis by N-methyl-N'-nitro-N-nitrosoguanidin (MNNG), was investigated in Wistar rats. The GSH content was found to be reduced by MNNG treatment, but increased on adding extract. In addition the Xanthium strumarium L. extract increased p53 expression versus MNNG alone.

• Korean Journal of Microbiology
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• v.38 no.4
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• pp.281-286
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• 2002

Detection of Vibrio vulnificus in fish farm and searching for the bactericidal methods on this bacteria were studied. To detect this microorganism in sea water, mud, fish and mussels, selective isolation methods and detection of vvhA gene were used from January to October,2000. V. vulnificus was detected from May when the water temperature was over $17^{\circ}C$. From June to September, higher than $19^{\circ}C$, this bacteria could be isolated from most of the samples. Freezing and refrigerating did not inhibit the growth of V. vulnificus. Citric acid did not show the bactericidal effect, but more than 500 mg/l of EDTA did. With the aid of UV and photocatalyst, $TiO_{2}$ showed bactericidal effect after 15 minute treatment. Photocatalytic system consisted of glass bead coated with $TiO_{2}$ and UV illumination showed bactericidal effect on V. vulnificus at the turnover rate of 0.2/min.

• Journal of Haehwa Medicine
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• v.5 no.1
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• pp.185-198
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• 1996

After evaluation of antithrombotic effect of 40 herbs on platelet aggregation induced by ADP(Adenosine diphosphate), these results were obtained as follows: 1. Crude drugs exerting over 30 % of in Chinemys reevesii (Gray)hibition on platelet aggregation induced by ADP were Ganoderma japonicum (Fr.) Lloyd., Panax ginseng C. A. Mey., Gastrodia elata Bl., Thea sinensis, Chinemys reevesii (Gray), Cuscuta chinensis Lam., Cervus nippon Temminck., Biota orientalis (L.) Endl., Coriolus versicolor, Cinnamomum cassia Presl., Sophora flavescens Ait., Amomum villosum Lour., Carthamus tinctorius L., Rubus chingii Hu., Poria cocos (Schw.) Wolf., Laminana japonica Aresch., Ligustrum lucidum Ait., Angelica sineusis (Oliv.), Cyperus rotundas L., Ginkgo biloba L., Zingiber officinale Rosc., Prunus persica (L.) Batsch., Schizandra chinensis (Turcz.) Baill. and Plantago asiatica L.. 2. Of crude drugs having showed over 50% of inhibitory effect on platelet aggregation, at the concentration of $100{\mu}g/m{\ell}$, the inhibitory rates were 82.2% in Ganoderma japonicum (Fr.) Lloyd., 55% in Panax ginseng C. A. Mey., 50.8% in Gastrodia elata Bl., while at the concentration of $200{\mu}g/m{\ell}$, antithrombotic rates were 89.4% in Ganoderma japonicum (Fr.) Lloyd., 59.2% in Panax ginseng C. A. Mey., 57.9% in Thea sinensis, 52.7% in Gastrodia elata Bl.. These results suggest that the study sholuld be necessary on antithrombotic effect of solvent fractions of Ganoderma japonicum (Fr.) Lloyd., Panax ginseng C. A. Mey., Gastrodia elaha B1. and Thea sinensis and isolation of effective compound from above drugs.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.22 no.12
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• pp.1107-1115
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• 2011

In this paper, a headset multiple-input multiple-output(MIMO) antenna for on-body application is proposed and the antenna performance with body effect and the impact on human body are investigated. The proposed MIMO antenna is composed of two planar inverted-F antennas(PIFA) above ground plane and an isolator located between the two antennas enhance the isolation characteristic. Simulation was carried to analyze the effect of human body on antenna performance when a human body is located in the near field of the antenna. According to the measurement result, the diversity performance of the proposed antenna can be considered good since ECC(Envelope Correlation Coefficient), which commonly indicates the performance of a MIMO antenna, remains below 0.1 over the ISM band. The measured SAR values for antennas 1 and 2 are 0.575 W/kg and 0.571 W/kg, respectively when 250 mW input power in engaged. These values satisfy the FCC guideline which states that the 1-g average SAR should be lower than 1.6 W/kg.

• Journal of the Earthquake Engineering Society of Korea
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• v.9 no.4 s.44
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• pp.29-42
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• 2005

Total 350 borehole profiles were selected from the database of borehole logs in Seoul, for the site-specific seismic evaluation at two 4km${\times}$4km plain areas. Equivalent-linear site response analyses for the selected 350 sites were conducted based on shear wave velocity (Vs) Profiles, which were determined from the N-Vs correlation established using borehole seismic testing results in the inland areas of Korea. Most sites were categorized as site classes C and D based on the mean Vs to 30 m in depth (Vs30) ranging from 250 to 550 m/s. The she periods of the plains in Seoul ranging between 0.1 and 0.4 sec were significantly lower than those of the western US, from which the site coefficients in Korea were derived. For plains in Seoul, the site coefficients, Fa's and Fv's specified in the Korean seismic design guide, underestimate the ground motion in short-period (0.1-0.5 sec) band and overestimate the ground motion in mid-period (0.4-2.0 sec) band, respectively, because ol the differences in the geotechnical conditions between Seoul and the western US, although the Fa's in several sites overestimate the motion due to the base Isolation effect resulted from the soft layer in soil deposit.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.4
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• pp.52-58
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• 2016

Recently, interest in structural stability has increased due to earthquakes. Isolation systems can improve seismic ability without harming the functions and appearance of existing and new constructions, and they have established efficiency in foreign country that have experienced earthquakes. In this study, an isolation system is suggested using a natural rubber bearing (NRB) on a stainless water tank for stability assurance in an earthquake. A shaking table test was carried out to evaluate the seismic capacity of a non-isolated water tank and an isolated tank. Displacement meters in the water tank measured the behavior characteristics of the tanks, which were compared using artificial seismic waves of 0.154 g, 0.231 g, 0.341 g, and 0.348 g with water levels of 0.0 m, 1.5 m, and 2.5 m. At 2.5 m, a decrement effect was generally shown in the isolated water tank, and a bigger displacement occurred in the non-isolated water tank than in the isolated one at water levels of 0.0 m and 1.5 m. It is interpreted that the weight of different water levels affects the decrement effect. If seismic reinforcement is done, the isolated bearing should be designed while considering the fluid storage level.

• Journal of the Korean Society of Food Science and Nutrition
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• v.9 no.1
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• pp.15-22
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• 1980

In this study, two species of algae, Ecklonia stolonifera, Sargassum thunbergii and one species of marine plant, Zostera marina(rhizoid and stem) were collected and extamined to determine the extractability of water soluble protein and the influences of various factors including extraction time, temperature, ratio of sample vs solvent and pH upon the extractability were tested. The effects of precipitation treatments for isolation of algal protein from the extracts(TCA treatment, methanol treatment and pH control) were also tested. Amino nitrogen and total nitrogen of purified samples made by obtained optimum conditions were estimated. The effect of the ratio of sample vs solvent on extractability differed from species to species which was enhances at 1:100(w/v) in Sargassum thunbergii and Zostera marina while 1:150(w/v) for Ecklonia stolonifera. The effect of extraction time and temperature was revealed differently in all species which might be considered to be caused by differences in the constitution of algal tissues. But in case of TCA insoluble nitrogen, it was showed the maximum extractability at $40-50^{\circ}C$ for 1 hour extraction. The optimum pH for the ext action of total nitrogen was 9-12 while the optimum pH was 6-7 for TCA insoluble nitrogen. And the pH control appeared to be most effective in the influence of precipitation treatment for isolation of algal protein.