• Asian Pacific Journal of Cancer Prevention
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• 제15권24호
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• pp.10783-10786
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• 2015

Background: Smoking remains the major preventable cause of death worldwide, especially cancer-related death. Evidence clearly indicates that tobacco-related morbidity and mortality is reduced by smoking cessation. Pharmacists are well-positioned to provide tobacco cessation services an involvement of pharmacists in smoking cessation is encouraged by several organizations. While Indonesia's prevalence of smoking is in the first rank in Asian countries, none of the pharmacy schools in Indonesia are currently offering tobacco-related courses in their existing curricula at present. Our study aimed to develop and to evaluate the effectiveness of tobacco education (TE) for pharmacy students in Indonesia. Materials and Methods: A 6-hour TE was developed and evaluated using pre-test/post-test with control group design. A total of 137 fifth-year pharmacy students at Gadjah Mada University (GMU), Yogyakarta, were chosen as an intervention group while a total of 105 fifth-year students of Islamic University of Indonesia, (UII) served as the control group. Knowledge, perceived-role, self-efficacy, and ability to perform counseling using the 5A's framework were evaluated. Results: A significant improvement (P < 0.001) in knowledge, perceived-role, and self-efficacy was found in the intervention group but not in the control group. In addition, we revealed that 89.7% of the intervention group were able to perform counseling using 5A's. Conclusions: The developed TE significantly improved student knowledge, perceived-rolse, self-efficacy, and created an ability to perform cessation counseling. Integration of TE education in curricula of Indonesian pharmacy schools nation-wide should be encouraged.

• 한국정보통신학회논문지
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• 제19권8호
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• pp.1785-1796
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• 2015

본 논문에서는 각 단말에 2개 이상의 안테나의 간섭 정렬을 이용한 X채널에서 직교 및 준직교 시공간 블록 부호를 통하여 더 높은 다이버시티와 전력 이득을 달성하고자 했다. 제안한 방법으로 다이버시티 차수는 직교 시공간 블록 부호에서 최대에 도달한 반면, 준직교 시공간 블록 부호에서는 유효 채널 행렬의 비 직교성에 의해 약간의 성능 저하가 나타났다. 수신기의 유효 채널 행렬에서의 유리한 구조에 의해 단순 제로 포싱 수신기는 최대 다이버시티 차수를 달성하는 반면, 간섭 제거 수신기는 성능이 저하되었다. 기존의 방법과 비교했을 때, 시뮬레이션 결과는 제안된 방법이 같은 스펙트럼 효율을 얻으면서, 3-4개의 안테나의 각 단의 직교 시공간 블록 부호의 경우 각각 목표 비트 에러율 10^-4에서 14dB와 16.5bB의 이득을 얻는 것을 증명하였다. 또한 4개의 안테나의 각 단의 준직교 시공간 블록 부호의 경우 같은 목표 비트 에러율에서 10dB의 이득을 얻었다.

• Asian Pacific Journal of Cancer Prevention
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• 제13권12호
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• pp.5995-5998
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• 2012

Background: Colorectal cancer is one of most common cancers in women and men and one of the major causes of death due to neoplasia. Colonoscopy is considered as the most accurate diagnostic procedure to detect colorectal cancer at the earlier stages. Objectives: The current study aimed to evaluate the effects of an education program using the Theory of Planned Behavior on promoting behavioral intention among first degree relatives of colorectal cancer patients. Materials and Methods: A quasi-experimental study conducted to evaluate the effectiveness of an educational program to promote attitudinal factors associated with early detection of colorectal cancer in 99 first degree relatives of colorectal cancer patients aged more than 20 years in Yazd city, Iran. A researcher made questionnaire forwhich validity and reliability were confirmed by expert point of view and pilot testing was employed for data collection. Questionnaires were filled in before and after educational intervention. The registered data were transferred to SPSS 19 and analyzed by paired T-test, Man-Whitney and Wilcaxon. Results: Mean scores of knowledge, attitude, perceived behavioral control and intention regarding colorectal cancer increased after education significantly (P<0.05). Conclusions: Application of the Theory of Planned Behavior has positive influence on promoting intention behavior. It is therefore recommended to apply educational programs to promote behavioral intention.

• Asian Pacific Journal of Cancer Prevention
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• 제14권2호
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• pp.865-871
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• 2013

Background: The present qualitative study assessed the need, acceptability and appropriateness for implementing effective and culturally appropriate smoking prevention programs for adolescents in schools in Indonesia. Methods: Snowball sampling was used to recruit participants. The study sample comprised a mixture of staff in the education department, junior high school teachers and individuals who had taught junior high school students in Aceh Province, Indonesia. Data were collected through one hour in-depth face to face or telephone interviews and analyzed using a descriptive content analysis procedure. Results: School teachers and policy makers in education firmly supported the implementation of a school-based smoking prevention program in Aceh. An appropriate intervention for smoking prevention program in schools in Aceh should involve both health and Islamic based approaches, and be provided by teachers and external providers. Potential barriers to the program included smoker teachers and parents, time constraints of students and/or teachers, lack of teachers' ability, increase in students' load, the availability of tobacco advertising and sales, and lack of tobacco regulation and support from community and related departments. To increase program effectiveness, involvement of and coordination with other relevant parties are needed. Conclusions: The important stakeholders in Indonesian childhood education agreed that school-based smoking prevention program would be appropriate for junior high school students. An appropriate intervention for smoking prevention program for adolescents in schools in Indonesia should be appropriate to participants' background and involve all relevant parties.

• 대한약침학회지
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• 제23권4호
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• pp.212-219
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• 2020

Objectives: Nowadays cancer treatment is an important challenge in the medical world that needs better therapies. Many active secretions produced by insects such as honey bees used to discover new anticancer drugs. Bee venom (BV) has a potent anti inflammatory, anti cancer and tumor effects. The aim of present study is evaluation of anticancer effects induced by Apis mellifera venom (AmV) on cell Lines. Methods: AmV was selected for study on cancer cell lines. Total protein, molecular weight and LD50 of crude venom were determined. Then, cells were grown in Dulbecco's Modified Eagle medium supplemented with 10% fetal bovine serum and 1% antibiotics. The A549, HeLa and MDA-MB-231 cell Lines were exposed by different concentration of AmV. The morphology of cells was determined and cell viability was studed by MTT assay. Evaluation of cell death was determined by and DNA fragmentation. Results: The results from MTT assay showed that 3.125 ㎍/mL of A549, 12.5 for HeLa and 6.25 ㎍/mL of MDA-MB-231 killed 50% of cells (p < 0.05). Morphological analysis and the results from hoescht staining and DNA fragmentation indicated that cell death induced by AmV was significantly apoptosis. Conclusion: The data showed that using lower dosage of AmV during treatment period cause inhibition of proliferation in time and dose dependant manner. Findings indicated that some ingredients of AmV have anticancer effects and with further investigation it can be used in production of anticancer drugs.

• Structural Engineering and Mechanics
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• 제82권3호
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• pp.295-312
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• 2022

This study investigates the effects of nano silica (NS) and micro steel fiber on the properties of ultra-high-performance concrete (UHPC). The experimental consists of three groups, each one with five percentages of NS content (0%, 2%, 4%, 6% and 8%) in addition to the 20% silica fume and 20% quartz powder proportioned according to the weight of cement added to the mixtures. In addition, three percentages of micro steel fibers (0%, 1% and 2%) were considered. Different mixtures with varying percentages of NS and micro steel fibers were prepared to set the water-to-binder ratio, such as 0.16% and 1.8% superplasticizer proportioned according the weight of the binder materials. The fresh properties, mechanical properties and elevated temperatures of the mixtures were calculated. Then, the results from the microstructure analyses were compared with that of the reference mixtureand it was found that 6% replacement of cement with NS was optimum replacement level. When the NS content was increased from 0% to 6%, the air content and permeability of the mixture decreased by 35% and 39%, the compressive and tensile strength improved by 21% and 18% and the flexural strength and modulus of elasticity increased by 20% and 11.5%, respectively. However, the effect of micro steel fibres on the compressive strength was inconclusive. The overall results indicate that micro steel fibres have the potential to improve the tensile strength, flexure strength and modulus of elasticity of the UHPC. The use of 6% NS together with 1% micro-steel fiber increased the concrete strength and reduce the cost of concrete mix.

• Clinical and Experimental Vaccine Research
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• 제12권1호
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• pp.25-31
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• 2023

Purpose: Since late 2019, the novel coronavirus disease has been a global concern, and alongside preventive strategies, including social distancing and personal hygiene, vaccination is now the primary hope for controlling the pandemic. Sputnik V is an adenovirus vector vaccine used against coronavirus disease 2019 (COVID-19) among Iranian health care providers, and there is a lack of information regarding the Adverse Events Following Immunisation (AEFI) by Sputnik V among the Iranian population. The present study aimed to evaluate AEFI by Sputnik V vaccine among Iranian population. Materials and Methods: Every member of the Islamic Republic of Iran Medical Council received their first dose of the Sputnik V vaccine in Mashhad (Iran) and was referred to receive their second dose enrolled in the present study and asked to fill an English language checklist asking about development of any AEFI following immunization with the first dose of Sputnik V vaccine. Results: A total number of 1,347 with a mean±standard deviation age of 56.2±9.6 years filled the checklist. Most of the participants were male (838 [62.2%]). The present study demonstrated that immunization with the first dose of Sputnik V results in at least one AEFI in 32.8% of the Iranian medical council members. Most of the AEFI was related to musculoskeletal symptoms, including myalgia. By considering the age of 55 years as a cut-off point, individuals younger than 55 had a higher rate of AEFI (41.3% vs. 22.5%, p=0.0001). Male gender, use of analgesics, beta-blockers, and previous COVID-19 infection have a lower chance of developing AEFI (p<0.05). Conclusion: The present study demonstrated that most of the AEFI was related to musculoskeletal symptoms, including myalgia, and older individuals, male gender and those receiving analgesics and beta-blockers were less likely to develop AEFI following immunization with the first dose of Sputnik V.

• The Journal of Asian Finance, Economics and Business
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• 제7권12호
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• pp.293-308
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• 2020

This study aims to investigate the direct relationship between ownership structure, earnings manipulation, and organizational performance, and then examine the mediating effect of earnings manipulation in the relationship between ownership structure and organizational performance. This study collected and analyzed secondary data published in financial reports related to all insurance organizations listed in the Jordanian market during the study period (from 2009 until 2018). A panel data analysis was conducted, giving a total of 200 observations. The findings of this study concluded that ownership concentration, foreign ownership, and organization size affect organizational performance proxied by ROA, ROE, and EPS, more specifically, ownership concentration and organization size have a positive effect, whereas foreign ownership has a negative effect. At the same time, board of director ownership, organizational ownership, and CEO compensation did not affect organizational performance. Next, the board of director ownership, ownership concentration, foreign ownership, and CEO compensation affect earnings manipulation separately. In addition, earnings manipulation positively affects organizational performance proxied by ROA, ROE and EPS. This means that the higher the earnings manipulation is, the higher the organizational performance is. Finally, earnings manipulation mediates the relationship between ownership concentration and foreign ownership of ownership structure, and organizational performance.

• Steel and Composite Structures
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• 제28권4호
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• pp.483-494
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• 2018

In this research the effect of high strength concrete (HSC) on shear capability of the channel shear connectors (CSC) in the steel concrete composite floor system was estimated experimentally and analytically. The push-out test was carried out for assessing the accurateness of the proposed model (nonlinear and finite element model) for the test specimens. A parametric analysis was conducted for predicting the shear capacity of the connectors (CSC) in the HSC. Eight push-out specimens of different sizes with different strength levels were tested under the monotonic loading system. The aim of this study was to evaluate the efficacy of the National Building Code of Canada (NBC) of Canada for analysing the loading abilities of the CSC in the HSC. Using the experimental tests results and verifying the finite element results with them, it was then confirmed by the extended parametric studies that the Canadian Design Code was less efficient for predicting the capacity of the CSC in the HSC. Hence, an alternative equation was formulated for predicting the shear capacity of these connectors during the inclusion of HSC for designing the codes.

• Asian Pacific Journal of Cancer Prevention
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• 제15권16호
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• pp.6531-6534
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• 2014

Background: In Iran, breast cancer is the most prevalent cancer in women and a major public health problem. Methods: A cross sectional study was carried out to determine knowledge on breast cancer and breast self-examination (BSE) practices of 384 females living in the city of Hamadan, Iran. A purposive sampling method was adopted and data were collected via face-to-face interviews based on a validated questionnaire developed for this study. Results: Among respondents 268 (69.8%) were married and 144 (37.5%) of the respondents reported having a family history of breast cancer. One hundred respondents (26.0%) claimed they practiced BSE. Level of breast cancer knowledge was significantly associated with BSE practice (p=0.000). There was no association with demographic details (p<0.05). Conclusion: The findings showed that Iranian women's knowledge regarding breast cancer and the practice of BSE is inadequate. Targeted education should be implemented to improve early detection of breast cancer.