• The Korean Journal of Physiology and Pharmacology
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• v.3 no.2
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• pp.119-125
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• 1999

Mammalian gastric smooth muscles generate spontaneous rhythmic contractions which are associated with slow oscillatory potentials (slow waves) and spike potentials. Spike potentials are blocked by organic $Ca^{2+}-antagonists,$ indicating that these result from the activation of L-type $Ca^{2+}-channel.$ However, the cellular mechanisms underlying the generation of slow wave remain unclear. Slow waves are insensitive to $Ca^{2+}-antagonists$ but are blocked by metabolic inhibitors or low temperature. Recently it has been suggested that Interstitial Cells of Cajal (ICC) serve as pacemaker cells and a slow wave reflects the coordinated behavior of both ICC and smooth muscle cells. Small segments of circular smooth muscle isolated from antrum of the guinea-pig stomach generated two types of electrical events; irregular small amplitude (1 to 7 mV) of transient depolarization and larger amplitude (20 to 30 mV) of slow depolarization (regenerative potential). Transient depolarization occurred irregularly and membrane depolarization increased their frequency. Regenerative potentials were generated rhythmically and appeared to result from summed transient depolarizations. Spike potentials, sensitive to nifedipine, were generated on the peaks of regenerative potentials. Depolarization of the membrane evoked regenerative potentials with long latencies (1 to 2 s). These potentials had long partial refractory periods (15 to 20 s). They were inhibited by low concentrations of caffeine, perhaps reflecting either depletion of $Ca^{2+}$ from SR or inhibition of InsP3 receptors, by buffering $Ca^{2+}$ to low levels with BAPTA or by depleting $Ca^{2+}$ from SR with CPA. They persisted in the presence of $Ca^{2+}-sensitive$ $Cl^--channel$ blockers, niflumic acid and DIDS or $Co^{2+},$ a non selective $Ca^{2+}-channel$ blocker. These results suggest that spontaneous activity of gastric smooth muscle results from $Ca^{2+}$ release from SR, followed by activation of $Ca^{2+}-dependent$ ion channels other than $Cl^-$ channels, with the release of $Ca^{2+}$ from SR being triggered by membrane depolarization.

• Korean Journal of Veterinary Research
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• v.47 no.4
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• pp.469-473
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• 2007

This study was performed to investigate the effects of urinary acupoint (BL-23, BL-28) by acupuncture (AP) and electroacupuncture (EA) on urinary bladder in dogs. Four healthy male dogs aged within the range of 6~8 months were used in this experiment. For Electrodes implantation on the bladder, dogs were to undergo surgical operation. The purpose of investigating the effect on urinary bladder was to evaluate electromyogram (EMG) changes according to AP or EA at Shen Shu (BL-23), Pang Guang Shu (BL-28) and non-acupoint. AP and EA (2~4 V, 10 Hz) were applied for 20 min to each point. EMG was evaluated when acupuncture began stimulation and as soon as the stimulation by electroacupuncture was gone. By the experiment of investigating the effect of urinary time it was estimated to measure time up to urination from stimulation on effective acupoint, after saline was filled with 70% of whole volumes on urinary bladder. The wave of EMG on resting stage showed simple and regular, whereas that of EMG on urination showed irregularly strong peaks before urination. Acupuncture of BL-28 had an influence on changes of EMG which had irregular peaks on urination. But the changes of EMG after acupuncture of BL-28 and control were regular like resting stage. The changes of EMG after EA at BL-23 and BL-28 showed irregularly a variety of wave forms. The interval through urination from stimulation at BL-28 and control become short as measuring time by EA (p<0.01). According to the results, AP at BL-28 was effective to urinary bladder. EA at BL-23 and BL-28 was effective to urinary bladder. Especially, the interval on stimulating at BL-28 by EA was the shortest in measuring time to urination from stimulation.

• Journal of Korea Water Resources Association
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• v.44 no.3
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• pp.249-262
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• 2011

In this study, in order to reduce the numerical oscillation due to the unbalance between source and flux terms as the HLLC scheme is applied to the flow analysis on the irregular bed topography, a unstructured finite volume model based on the well-balanced HLLC scheme and the shallow water equations is developed and applied to problems of dam-break waves. The well-balanced HLLC scheme considers directly the gradient of bed topography as the flux terms is calculated. This scheme provides the good numerical balance between the source and flux terms in the case of the application to the steady-state transcritical flow. To verify the numerical model developed in this study, it is applied to three cases of hydraulic model experiments and a field case study of Mapasset dam failure (France). As a result of the verification, the predicted numerical results agree relatively well with available laboratory and field measurements. The model provides slightly more accurate results compared with the existing models.

• Geophysics and Geophysical Exploration
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• v.4 no.2
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• pp.34-44
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• 2001

Forward modeling by construction of synthetic data is usually practiced in a horizontal surface and a few subsurface structures. However, in-situ surveys often take place in such topographic changes that the corrupted field data always make it difficult to interpret the right signals. To examine the propagation characteristic of elastic waves on the irregular surface, a general mesh generation code for finite element method was modified to consider the topography. By implementing this algorithm, the time domain modeling was practiced in some models with surface topography such as mound, channel, etc. The synthetic data obtained by receivers placed on surface also agreed with the analytic solution. The snapshots showing the total wave-field revealed the propagation characteristic of the elastic waves through complex subsurface structures and helped to identify the signals on the time traces. The transmission of Rayleigh waves along the surface, compressive waves, and sheer waves was observed. Moreover, it turned out that the Rayleigh waves behave like a new source at the edge.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2018.11a
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• pp.241-247
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• 2018

Deep-sea fishing vessel No. 501 Oryong was fully flooded through its openings and sunk to the bottom of the sea due to the very rough sea weather on the way of evasion after a fishing operation in the Bearing Sea. As a result, many crew members died and/or were missing. In this study, a full-scale ship flooding and sinking simulation was conducted, and the sinking process was analyzed for the precise and scientific investigation of the sinking accident using a highly advanced Modeling & Simulation (M&S) system of the Fluid-Structure Interaction (FSI) analysis technique. To objectively secure the weather and sea states during the sinking accident in the Bering Sea, time-based wind and wave simulation at the region of the sinking accident was conducted and analyzed, and the weather and sea states were realized by simulating the irregular strong wave and wind spectrums. Simulation scenarios were developed and full-scale ship and fluid (air & seawater) modeling was performed for the flooding sinking simulation, by investigating the hull form, structural arrangement & weight distribution, and exterior inflow openings and interior flooding paths through its drawings, and by estimating the main tank capacities and their loading status. It was confirmed that the flooding and sinking accident was slightly different from a general capsize and sinking accident according to the simple loss of stability.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.35 no.4
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• pp.281-286
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• 2007

The Navier-Stokes equations are numerically solved for a two-dimensional small nozzle with the area ratio of 1.8 between the throat and the exit. The shock structures are verified inside the nozzle and near the exit varying with the pressure ratio and the length of the diverging part, respectively. Especially the irregular patterns in the pressure distribution near the throat are analyzed based on the geometric characteristics. It is found that there are similar phenomena in the shock wave structure between the pressure ratio and the length changes. Also there exists a normal shock just between two different oblique shocks crossing each other in special cases.

• Journal of Navigation and Port Research
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• v.36 no.8
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• pp.659-664
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• 2012

Coastal vegetaion consists of rooted flowering marine plants that provide a variety of ecosystem services to the coastal areas they colonize. The attenuation of waves and sediments stabilization are often listed among these services. From this point of view, artificial vegetation model is an effective method of controlling sea bed and stabilization without damaging the landscape or the stability of the coastaline. In this study, numerical and hydraulic physical test for predicting deposition proces of a navigation channel caused by wave action is proposed. In the numerical model, we develop a numerical model for describing the wave attenuation and sediment transport in a navigation channel with a vegetation area. In addition, hydraulic model tests is performed in a navigation channel with irregular waves to examine the effect of vegetation in relation to deposition reduction in navigation channel. A comparison between the results of hydraulic and numerical tests shows resonable agreement.

• International Journal of Naval Architecture and Ocean Engineering
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• v.12 no.1
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• pp.213-225
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• 2020

Floating Offshore Wind Turbines (FOWT) installed in the deep sea regions where stable and strong wind flows are abundant would have significantly improved energy production capacity. When designing FOWT, it is essential to understand the stability and motion performance of the floater. Water tank model tests are required to evaluate these aspects of performance. This paper describes a model test and numerical simulation for a 750-kW semi-submersible platform wind turbine model-II. In the previous model test, the 750-kW FOWT model-I suffered slamming phenomena from extreme wave conditions. Because of that, the platform freeboard of model-II was increased to mitigate the slamming load on the platform deck structure in extreme conditions. Also, the model-I pitch Response Amplitude Operators (RAO) of simulation had strong responses to the natural frequency region. Thus, the hub height of model-II was decreased to reduce the pitch resonance responses from the low-frequency response of the system. Like the model-I, 750-kW FOWT model-II was built with a 1/40 scale ratio. Furthermore, the experiments to evaluate the performance characteristics of the model-II wind turbine were executed at the same location and in the same environment conditions as were those of model-I. These tests included a free decay test, and tests of regular and irregular wave conditions. Both the experimental and simulation conditions considered the blade rotating effect due to the wind. The results of the model tests were compared with the numerical simulations of the FOWT using FAST (Fatigue, Aerodynamics, Structures, and Turbulence) code from the National Renewable Energy Laboratory (NREL).

• Journal of the Society of Naval Architects of Korea
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• v.59 no.5
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• pp.252-261
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• 2022

The present study concerns assessing the operability of a surface combatant, based on the Percent-Time-Operable (PTO). For validation of the seakeeping analysis in the regular waves, the model test is first conducted in a towing tank. The seakeeping analysis results in the regular waves are expanded to the irregular waves, considering the wave spectra around the Korean peninsula and in North Pacific. The seakeeping criteria of the surface combatant in transit, combat, replenishment operation, and survival condition are defined by the literature review. An annual operation scenario of the surface combatant in two operation areas, i.e., advance speed and wave direction, are combined with the seakeeping analysis results to assess PTO. The main constraints of operability of the surface combatant are identified as the pitch angle and vertical velocity at the helicopter deck.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.26 no.1
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• pp.49-64
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• 2014

Seabed beneath and near the coastal structures may undergo large excess pore water pressure composed of oscillatory and residual components in the case of long durations of high wave loading. This excess pore water pressure may reduce effective stress and, consequently, the seabed may liquefy. If the liquefaction occurs in the seabed, the structure may sink, overturn, and eventually fail. Especially, the seabed liquefaction behavior beneath a gravity-based structure under wave loading should be evaluated and considered for design purpose. In this study, to evaluate the liquefaction potential on the seabed, numerical analysis was conducted using 2-dimensional numerical wave tank. The 2-dimensional numerical wave tank was expanded to account for irregular wave fields, and to calculate the dynamic wave pressure and water particle velocity acting on the seabed and the surface boundary of the structure. The simulation results of the wave pressure and the shear stress induced by water particle velocity were used as inputs to a FLIP(Finite element analysis LIquefaction Program). Then, the FLIP evaluated the time and spatial variations in excess pore water pressure, effective stress and liquefaction potential in the seabed. Additionally, the deformation of the seabed and the displacement of the structure as a function of time were quantitatively evaluated. From the analysis, when the shear stress was considered, the liquefaction at the seabed in front of the structure was identified. Since the liquefied seabed particles have no resistance force, scour can possibly occur on the seabed. Therefore, the strength decrease of the seabed at the front of the structure due to high wave loading for the longer period of time such as a storm can increase the structural motion and consequently influence the stability of the structure.