• 여성건강간호학회지
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• 제10권3호
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• pp.226-234
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• 2004

Purpose: This study was to examine health status, reproductive health problems and the degree of prenatal management in working women. Method: The subjects were 902 married working women among 2,000 women selected by cluster sampling. The work area was classified to product factory, school, office, etc. After an Informed consent was obtained, participants were asked to fill out a self-administered questionnaire. The instruments included a questionnaire, parity check list, menstrual problems and gynecologic problem check list. Result: Many women have experienced menstrual cycle change during the past year. There was a significant difference in general health, menstrual regularity, reproductive health and prenatal management by occupation type. 40.6 percent of the subjects have gynecological problems such as menstrual cycle change, perineal inflammation, irregular vaginal bleeding, amenorrhea, ovarian/uterine disease, infertility, or abortion. Prenatal care was received in only 28.5% of the total subjects. In addition, 16.3% answered they had experienced low birth weight babies. Conclusion: We can conclude that working woman have changes in menstruation cycle and in reproductive health status. Therefore, we suggest that some occupational characteristics may affect subject's reproductive health, these should be clear and avoided as much as possible.

• 동의생리병리학회지
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• 제16권5호
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• pp.888-892
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• 2002

Nae-Kyung says the puberty is corresponded to the age of 16～24(male) and 14～21 (female). And that time they are promoted the growth. However, Kidney qi doesn't make average situation during that time. So, the function of five viscera and six entrails fails to be perfect and symptoms appear. I came to the conclusion through the survey of about 200 high school students(male and female) and the theory of oriental medicine the distinctive features (like migraine, amnesia, depression, dysphoria, inappetence, irregular menstruation) came out that time. I defined this distinctive symptoms in boys and girls at puberty ‘synthetic symptoms of puberty’. For the medical cure and prevention I prescribed ‘Sachun-Nyung’ and that has medical benefits for ‘Replenishing qi and relieving the spleen, Soothing the liver and promoting blood circulation’

• 대한한의학회지
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• 제24권4호
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• pp.34-42
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• 2003

This study was designed to investigate the modulation of the Corydalis tuber on glycine-activated ion current in rat periaqueductal gray (PAG) neurons. Aqueous extract from Corydalis tuber has been widely used for pain control such as dysmenorrhea, irregular menstruation or amenorrhea with abdominal cramping, neuralgia, headache and gastrointestinal spasm. The PAG region of the brain is known to be involved heavily with nociception. Modulation of the Corydalis tuber on glycine-induced ion current in rat periaqueductal gray (PAG) neurons was studied by a nystatin-perforated patch-clamp technique. High concentrations of Corydalis tuber elicited ion current, which was suppressed by strychnine application. Low concentrations of Corydalis tuber reduced glycine-induced ion currents in the PAG neurons. Inhibitory action of Corydalis tuber on glycine-activated ion current was reduced by treatment with naltrexone, a non- selective opioid antagonist. Application of N-methylmalemide (NEM), a sulfhydryl alkylating agent, also reduced the inhibitory action of Corydalis tuber on glycine-activated ion current in the PAG neurons. These results suggest that the inhibitory effect of Corydalis tuber on glycine-activated ion current in the PAG neurons is one of the analgesic mechanisms of the Corydalis tuber, which may activate descending pain control system in PAG neurons.

• 여성건강간호학회지
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• 제6권4호
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• pp.528-548
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• 2000

The purpose of this study was to identify the effect of college women s active and passive smoking on menstrual discomfort. The subjects were 252 college female students (active smokers, 71; people who passively inhaled others smoke, 104; nonsmokers who also didn't inhale others smoke, 77). Subjects were selected from 5 colleges in North Kyong Sang Province, Korea. Data was collected from March to June of 2000 with a structured questionnaire. The instruments used for this study were the revised Menstrual Distress Questionnaire (MDQ) developed by Moos(1968), general characteristic, menstrual characteristic, and smoking characteristic scale developed by researchers. The data were analysed by the SPSS/PC+ program. The results were as follows 1. There was no statistically significant difference of menstrual discomfort level among the active smokers, those who passively inhaled others smoke, and who did not inhale others smoke(F= 2.613, p= .075). 2. The mean score of menstrual discomfort was moderate(M= 60.8008, SD= 17.9243). The level of menstrual discomfort was various (minimum score 29.00- maximum score 110.0). 3. Factors influencing menstrual discomfort were on life stress events(F= 4.057, p = .045), irregular menstrual cycle(t = 3.968, p = .047), and amount of flow during menstruation(F = 4.018, p = .019). The recommendations from this study are necessity of further studies to investigate how heavy active and passive smoking have effect on menstrual discomfort.

• 사상체질의학회지
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• 제15권3호
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• pp.118-123
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• 2003

The climacteric is the period of passage out of the reproductive stage of life and into the nonreproductive phase. The climacteric can be accompanied by wide-ranging, uncomfortable and disruptive symptoms. Symptoms that are related to hormonal changes include abnormal bleeding, facial flushing, and urogenital discomfort. This patient was 45- year-old woman who had headache, facial flushing, thirst, fatigue, irregular menstruation, urogenital discomfort and had been diagnosed and teated climacteric. We classified this patient as Soyangin(少陽人) Yin collapsed ease(亡陰證) and prescribed Hyeongbangsabaeksan(荊防瀉白散). We experienced the good effect of Hyeongbangsabaeksan on Soyangin Mangyin-disease We report the healing process and the result of treatment in this study.

• 대한한의학회지
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• 제20권4호
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• pp.11-15
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• 2000

Radix Angelicae Gigantis is sweet and pungent in flavor, warm in property. Its effects are tonifying the blood, promoting blood circulation, relieving pain and moistening the bowels. Its indications are blood deficiency syndrome characterized by sallow complexion, dizziness, irregular menstruation, amenorrhea, pains due to blood stasis, and rheumatic arthralgia. Using genes of A. gigas, A. acutiloba, and A. sinensis, the origin of which is identified, as criteria, we analysed many kinds of Angelica with RAPD and RFLP on ITS region, in order to compare and discriminate genes extracted from crude drugs ‘Dang-gui’, that are produced in Korea on the one hand and imported on the other hand. We reached the following conclusion. 1. We could extract DNA from both original plant and dried plant. 2. Especially Uniprimer #1, Uniprimer #2, Uniprimer #4 and Uniprimer ＃9 were useful. 3. Among the restriction enzymes Sma I, Msp I, Hae III, and Hinf I, used in this experiment, four restriction enzymes except Hinf I could be used properly in discriminating all samples used as A. gigas. We think that this result can be used as a method of discriminating crude drug of Angelica L. related drugs, and used in controlling quality and circulation.

• 대한한방부인과학회지
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• 제32권4호
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• pp.170-180
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• 2019

Objectives: The purpose of this study is to report the case of Korean medicine treatment on primary ovarian insufficiency. Methods: The patient in this case was 29-year-old female who was diagnosed with primary ovarian insufficiency. She had irregular menstruation and hypomenorrhea more than 6 months. She also suffered from hot flash and vaginal dryness. She was treated over 1 year with Korean medicine treatment, such as herbal medicine, acupuncture, and pharmacopuncture. We assessed the clinical symptoms, menstrual status and serum hormone level during the treatment. Results: After treatment, symptoms of primary ovarian insufficiency were relieved, level of serum FSH decreased and level of serum E2 increased. We maintained the treatment over 1 year and kept follow-up measurements of serum hormone level. Conclusions: This study shows that Korean medicine treatment can be effective in treating primary ovarian insufficiency. The report suggests the long treatment procedure for primary ovarian insufficiency.

• 대한한방부인과학회지
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• 제25권1호
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• pp.56-69
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• 2012

Objectives: This study was conducted to investigate the relationship between menstrual conditions and items of health checkup examinations in female university students for prediction of reproductive health. Methods: Data from the 2011's medical examination participants(990 students among total 1,699 students) of ${\bigcirc}{\bigcirc}$ University University in Korea were analyzed for this study. Menstrual condition, Sa-sang constitution and other surveys were checked through self-administered questionnaire, health checkup were measured anthropometric variables, CBC, B/C and U/A. Results: In the 46.4% of total participants appeared menstrual disorder of menstrual cycle or menstrual amount, the irregular period of menstrual cycle have a influence on menstrual amount. stress was relatively heavy factor of causing irregularity of menstrual cycle and amount, RBC, cholesterol, ABO type and Sa-sang constitution had some connection with menstrual amount. Conclusions: Among the items of health checkup examinations, stress, RBC, cholesterol, ABO type and Sa-sang constitution were related with the change of menstrual cycle and amount.

• Clinical and Experimental Reproductive Medicine
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• 제48권3호
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• pp.194-197
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• 2021

Polycystic ovary syndrome (PCOS) is a common disorder in reproductive-age women. In 2018, an international evidence-based guideline announced recommendations spanning a wide range of issues on the assessment and management of PCOS. From the 166 recommendations, the present study reviews those that are of particular clinical relevance for daily practice and introduces other relevant studies that have been published since the global guideline. The 2018 guideline increased the antral follicle count cutoff for the diagnosis of PCOS from 12 to 20 when using a high-frequency probe. Hirsutism was defined as having a score of ≥4-6 based on a lower percentile of 85%-90% or cluster analysis, which was lower than the traditionally used 95th percentile-based cutoff. The diagnosis of PCOS in adolescents is challenging, and irregular menstruation was defined carefully according to years from menarche. The use of ultrasonography for the diagnosis of PCOS was restricted to those 8 years after menarche. As medication for non-fertility indications, combined oral contraceptives are the first-line drug. Metformin, in addition to lifestyle modifications, should be considered for adult patients with a body mass index ≥25 kg/m² for the management of weight and metabolic outcomes. An aromatase inhibitor is the recommended first-line medication for ovulation induction, a subsequent individual patient data meta-analysis also reported the same conclusion. Whether the new global guideline will be fully adopted by many specialists and change clinical practice is open to question. Further studies are needed to better understand and manage PCOS patients well.

• 생명과학회지
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• 제20권6호
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• pp.894-901
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• 2010

본 연구는 부산지역 결혼이주여성의 생식건강상태와 체성분 조성을 파악하여 결혼이주여성의 건강증진을 위한 기초자료를 제공하기 위해 수행된 서술적 조사연구이다. 연구대상은 부산시에 거주하고 있는 결혼이주여성 154명이었으며. 자료수집 기간은 2008년 7월 21일부터 2009년 7월 25일까지였다. 결혼이주여성의 일반적인 특성, 생식건강상태를 측정하기 위해 구조화된 설문지를 사용하였고 신체계측과 체성분 검사를 하였다. 대상자의 연령에 따라 체외수정 경험, 임신경험과 유산경험이 유의한 차이를 나타내었으며 대상자의 국적에 따라 월경, 월경 전 증후군, 지난 1년간 월경의 규칙성, 질 분비물에서의 냄새, 체외수정 시술경험, 분만경험, 모유수유경험이 유의한 차이를 보였다. 대상자의 한국 내 체류기간에 따라 체외수정 시술경험, 임신경험, 분만경험과 모유수유경험이 유의한 차이를 보였고 대상자의 종교유무에 따라 월경 전 증후군, 생식기감염 치료경험과 모유수유경험이 유의한 차이를 보였다. 대상자의 자녀유무에 따라 월경통, 임신경험, 분만경험, 출산합병증과 모유수유경험이 유의한 차이를 보였다. 대상자의 체지방률은 국적과 종교유무에 통계적으로 유의한 차이를 보였으며 체질량지수는 연령, 국적 및 체류기간에 따라 통계적으로 유의한 차이를 보였다. 허리와 엉덩이 둘레 비는 연령, 국적 및 종교유무에 따라 통계적으로 유의한 차이를 보였다. 결혼이주여성의 연령과 출신국가 별 특성을 고려한 체계적인 건강관리 및 영양관리 프로그램 개발이 요구된다.