• 제목/요약/키워드: Irradiation effects

검색결과 1,818건 처리시간 0.029초

Effect of quercetin on impaired immune function in mice exposed to irradiation

  • Jung, Ji-Hye;Kang, Ji-In;Kim, Hyun-Sook
    • Nutrition Research and Practice
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    • 제6권4호
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    • pp.301-307
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    • 2012
  • Radiation used in cancer treatment may cause side effects such as inflammation. Quercetin is a polyphenol that reduces inflammation. This study evaluated the recovery efficacy of quercetin on impaired immune function in irradiation-induced inflammatory mice. Quercetin administered at two concentrations of 10 and 40 mg/kg body weight was initiated 2 weeks before irradiation and was continued 30 days after irradiation. The animals exposed/not exposed to radiation were sacrificed on radiation days 10 and 30. Splenocyte proliferation, which was diminished after irradiation, was enhanced significantly by quercetin supplementation after 30 days of irradiation. Cytokine secretion increased in the radiation group compared to that in the non-radiation control group. After 30 days of radiation, interleukin (IL)-$1{\beta}$ and IL-6 secretion decreased significantly in the radiation-quercetin groups. When quercetin was administered for 44 days, it showed a possible protective effect against irradiation-induced inflammation in mice. Quercetin could be beneficial in the recovery of irradiation-induced increases in cytokine secretion.

Development of a gamma irradiation loop to evaluate the performance of a EURO-GANEX process

  • Sanchez-Garcia, I.;Galan, H.;Nunez, A.;Perlado, J.M.;Cobos, J.
    • Nuclear Engineering and Technology
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    • 제54권5호
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    • pp.1623-1634
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    • 2022
  • A new irradiation loop design has been developed, which provides the ability to carry out radiolytic resistance studies of extraction systems simulating process relevant conditions in an easy and simple way. The step-by-step loop configuration permits an easy modification of settings and has a relative low volume requirement. This irradiation loop has been initially set up to test the main EURO-GANEX process steps: the lanthanide (Ln) and actinide (An) co-extraction followed by the transuranic (TRU) stripping. The performance and changes in the composition have been analyzed during the irradiation experiment by different techniques: gamma spectroscopy and ICP-MS for the extraction and corrosion behavior of the full system, and HPLC-MS and Raman spectroscopy to determine the degradation of the organic and aqueous solvents, respectively. The Ln and An co-extraction step and the corrosion that occurred during the first irradiation step revealed the favorable expected results according to literature. The effects of acidity changes occurred during the irradiation process, the presence of stainless corrosion products in solution as well as the new possible degradation compounds have been explored in the An stripping step. The results obtained demonstrate the importance of developing realistic irradiation experiments where different factors affecting the performance can be easily studied and isolated.

혈관내(血管內) Helium-Neon Laser 조사(照射)가 혈중(血中) Total Cholesterol 및 Triglyceride 수치변화(數値變化)에 미치는 영향(影響) (The effects of Helium-Neon(He-Ne) laser irradiation on high-lvevel of Total Cholesterol and Triglyceride)

  • 백은탄;민재영;국윤형;오상덕;라수연;임승만
    • 대한한방내과학회지
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    • 제21권5호
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    • pp.799-803
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    • 2000
  • Objective : This study was designed to assess effects of He-Ne laser irradiation on high-level of Total Cholesterol and Triglyceride. Methods : The 76 patients who have been checked Total Cholesterol and Triglyceride high were divided into a study group of patient who were irradiated and into a control group of patients who did not receive irradiation.. Then, patients rechecked Total Cholesterol and Triglyceride after 1 month later. Results : In patients of study group, The level of Total Cholesterol and Triglyceride was decreased. But In comparison with control group, there was no significant effect of decrement of Total Cholesterol and Triglyceride. Conclusions : These results suggest that He-Ne laser irradiation may have no significant decrement effects on high-level of Total Cholesterol and Triglyceride.

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Effects of organic carbon and UV wavelength on the formation of dissolved gaseous mercury in water under a controlled environment

  • Lee, Jae-In;Yang, Ji-Hye;Kim, Pyung-Rae;Han, Young-Ji
    • Environmental Engineering Research
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    • 제24권1호
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    • pp.54-62
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    • 2019
  • The effects of UV wavelength and dissolved organic carbon (DOC) on the formation of dissolved gaseous mercury (DGM) were investigated in a controlled environment. To remove any other influences than UV wavelength and DOC, purified water was used as the working solution. DGM was instantly produced with irradiation of all UV lights even without DOC; whereas, there was no noticeable increase of DGM during irradiation of visible light. The amount of formed DGM increased as the DOC concentration increased even in dark conditions; however, UV-B irradiation significantly promoted DGM production with DOC present. The rate constants of reduction ranged from $1.4{\times}10^{-6}s^{-1}$ to $3.5{\times}10^{-5}s^{-1}$, with the lower values occurring under the dark condition without DOC and the higher values resulting under UV-B irradiation and high DOC concentration. However, DGM production was not linearly correlated with the DOC concentration at higher range of DOC in this study. Future studies should investigate the effects of DOC concentration on mercury (Hg) reduction over the broad range of DOC concentrations with different DOC structures and with other influencing parameters.

Design of a New Capsule Controlling Neutron Flux and Fluence and Temperature of lest Specimen

  • Choo, Kee-Nam;Kang, Young-Hwan;Taiji Hoshiya;Motoji Niimi;Takashi Saito
    • Nuclear Engineering and Technology
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    • 제29권2호
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    • pp.148-157
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    • 1997
  • A new capsule that has a unique structure in which the test environments including neutron flux and fluence, and irradiation temperature can be controlled precisely during irradiation, was conceptually designed. The capsule structure and instrumentation were successfully designed according to the JMTR's standard procedures of capsule design. Based on the target irradiation, the details of the irradiation such as neutron fluence and irradiation temperature ore calculated and the related capsule safety was evaluated. In addition, the effects of design parameters including the changes in inner-capsule configuration, heater capacity, and Helium gas pressure on the specimen temperature were analyzed with a computer program. Through these thermal and strength evaluations, this capsule was proved to be safe during the irradiation in the JMTR.

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Clinical Study on the Effect of Exterior Vascular Laser Irradiation Therapy by Live Blood Analysis

  • Lee, Eun-Hyoung;Jeong, Jae-Ook;Min, Sung-Soon;Song, Su-Jin;Kim, Won-Ill
    • 대한한의학회지
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    • 제26권4호
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    • pp.143-151
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    • 2005
  • Objectives: The purpose of this study was to investigate the effect of exterior vascular laser irradiation therapy by live blood analysis. Methods: We analysed the changing forms of the live blood sample with a microscope before and after exterior vascular laser irradiation therapy of the blood. Results: Rouleau of red cells, erythrocyte aggregation of red cells, thrombocyte aggregation, uric acid crystals, red crystals, and protoplasts in blood were decreased significantly after exterior vascular laser irradiation therapy. Conclusions: This study suggests that exterior vascular laser irradiation will have positive effects in eliminating various effete matters in blood and will have efficacy in the treatment and prevention of cardiovascular system disorders and hyperlipidemia, caused by effete matters, or numbness and arthralgia caused by blood stagnancy and blood circulation disorder.

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Properties of corn Starches Isolated from Irradiated Glutinous and Non-Glutinous Corn Grains

  • Kang, Il-jun;Byun, Myung-Woo;Yook, Hong-Sun;Lee, Soo-jeong;Chung, Cha-Kwon
    • Preventive Nutrition and Food Science
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    • 제2권1호
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    • pp.23-28
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    • 1997
  • Physicohemical properties of corn starches isolated from non-glutinous and corn grains fol-lowing γ-irradiation up to 10kGy were investigated. Blue value, water binding capacity and swelling power decreased, while alkali number ad solubility increased by γ-irradiation , which was more pronounced in glu-tinous corn starch than in non-glutinous corn starch. The optical transmittance increased with an increment of heating temperature and applied irradiation doses. No significant difference was observed in Hunter's color value between both starches isolated from non- irradiated and irradiated and irradiated corn grains. Amylograph viscosities decreased remarkably as dose levels increased. The overall effects of γ-irradiation was more distinguished in glutinous starch than in non-glutinous starch.

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감마선 조사가 기능성 식품 소재인 토사자의 휘발성 유기성분에 미치는 영향 (Effects of ${\gamma}$-Irradiation on the Volatile Organic Compounds from Cuscutae Semen (Cuscuta chinensis Lam))

  • 양수형;김경수
    • 통합자연과학논문집
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    • 제1권2호
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    • pp.115-121
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    • 2008
  • This study was performed to examine the effect of ${\gamma}$-irradiation on the volatile organic compounds of Cuscutae Semen (Cuscuta chinensis L.). The volatile organic compounds of non-irradiated and 10 kGy ${\gamma}$-irradiated Cuscutae Semen were isolated using SDE apparatus and analyzed by GC/MS. Limonene, ethanol, (E)-2-decenal, hexadecanol, nonanoic acid and nonanal were detected as dominant compounds. Before irradiation, the total concentration of volatile organic compounds of Cuscutae Semen was approximately 189.90 mg/kg. After irradiation at 10 kGy, total concentrations increased to 299.46 mg/kg, but, the profile of volatile compounds including the essential oils of Cuscutae Semen was not differ from non- and irradiated sample. Therefore it was improved the extraction yield of useful compounds such as limonene, menthol, piperitone and isomenthone by irradiation.

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홍삼 투여가 방사선에 조사된 생쥐 간세포의 Superoxide Dismutase, Peroxidase 및 Catalase 활성도에 미치는 영향 (The Effect of Red Ginseng Extracts on the Superoxide Dismutase, Peroxidase and Catalase Activities in the Liver of Gamma Ray Irradiated Mice)

  • 전철;장재철
    • Journal of Ginseng Research
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    • 제17권1호
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    • pp.29-34
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    • 1993
  • This study was undertaken to investigate the effect of red ginseng extract (5.5 mg/mouse ip) on the activities of superoxide dismutase (SOD), peroxidase and catalase in the liver of the gamma ray irradiated male mice. The experimental groups consisted of control, red ginseng extract injection group, irradiation (8 $Gy^{60}$Co) group and red ginseng extract injection after irradiation group. in red ginseng extract injection group, SOD, peroxidase and catalase activities were similar to that in the control group. In irradiation group SOD, peroxidase and catalase activities increased progressively until the 2nd day after the treatment and then decreased thereafter, whereas red ginseng extract injection after irradiation group recovered more rapidly than irradiation group. The above results suggested that red ginseng extract injection after irradiation group have the recovery effects on the activities of SOD, peroxidase and catalase after radiation injury in the liver of male mice.

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Effects of pH and Gamma Irradiation on the Physicochemical Properties of Corn Starch

  • Kang, Il-Jun;Chung, Cha-Kwon;Sohn, Jeong-In
    • Preventive Nutrition and Food Science
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    • 제4권3호
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    • pp.175-179
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    • 1999
  • To develop a production method for modified starches with less pollution, pH adjustment and gamma irradiation were applied to commerical corn starch. Blue values were significantly decreased , while alkali number, optical transmittance and solubility markedly increased when gamma irradiation was applied to pH 2 adjusted corn starch. Water binding capacity and swelling power at pH 5 were the highest among the samples. Gelatinization viscosity was considerably affected by gamma irradiation and pH of the starch. Gamma irradiation of pH 2 adjusted starch showed the lowest peak viscosity and the best cooling stability among the tested samples . Therefore, the production of modified starch with low viscosity as well as with sufficient viscosity stability seems feasible by controlling the pH of the starch and gamma irrdiation.

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