• Proceedings of the Korean Nuclear Society Conference
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• 1998.05b
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• pp.757-762
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• 1998

“하나로”를 이용하여 강내 조사용으로 사용되는 $^{192}$ Ir 선원의 제조법을 확립하였다. HTS (Hydraulic Transfer System)조사공에서 48시간 조사한 $\psi$2.5 mm x t 0.25 mm의 원판형 Ir 표적 10장을 쌓아서 방사능이 1.012 Ci인 선원을 시험제조하였다. 선원 제작에 관련된 생성방사능, 중성자 자기홉수효과 인자를 이론적으로 계산하여 시험제조에 사용하였고 ${\gamma}$선 자기흡수효과는 실험으로 측정하여 암 치료에 요구되는 10-20 Ci 선원의 상용생산에 필요한 자료를 확보하였다. 치료용 소선원 제작에 관련된 표적제작, 중성자조사, 방사능 측정, 선원조립, 밀봉용접, 품질관리 등의 제작기술을 확립하고 선원의 안전성은 밀봉시험, 표면오염검사 등을 수행하여 확인하였다. 제조된 선원은 실제 사용되는 조사장치에 장착하여 기능시험을 수행할 것이다. 이번 실험을 통하여 강내 조사용으로 사용되는 10-20 Ci 방사능의 $^{192}$ Ir 선원을 안정적으로 공급할 수 있음을 확인하였으며 하나로를 이용하여 캡슐 직경 4 mm의 치료용 소선원 제작기술을 확립하였다. 개발된 /spp 192/Ir 강내 조사용 선원은 국내 5-6개 병원에 공급할 것이며 이 기술을 바탕으로 직경 1.1-1.6 mm의 강내 조사용 선원도 개발할 예정이다.

• Progress in Medical Physics
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• v.14 no.2
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• pp.81-89
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• 2003

The dose distributions of designed Ir-192 micro-source were investigated by dose computations which were accomplished by employing shape of encapsule material and thickness of the source for self-absorption. The computation dose derived from air-kerma rate (S$_{k}$ ) and dose rate constant (Λ) includes the anisotropy of dose distribution around the source. We got the dose rate constants in a water medium is 1.154 cGy h$^{-1}$ U$^{-1}$ . The size of the source was 0.5 mm in diameter and 3.5 mm in length and it was encapsuled in 1.1 mm$\Phi$${\times}$5.5 mm of stainless steel sealed with 0.3 mm of filter thickness. The tissue dose of reference point at 1.0 cm radial distance of the source axis was delivered 1.154 Uh$^{-1}$ (1.3167${\times}$10$^{-3}$ cGy/mCi-sec) from the S$_{k}$ 4.108U/mCi of Ir-192 source. The filtration effect contributed to air-kerma strength as exponential filtering effect of 86.2% in total attenuation, but self-absorption was 88.4% from radial dose distributions. In particular, the dose attenuations showed a rapid anisotropic distributions as 56% of reference dose along to $\pm$10 degrees from the tip of source axis and 50% for of that to source-cable direction. We persist in use the large diameter of applicator will avoid the dose anisotropy by the filtered attenuation effects along the axis of Ir-192 micro-source.

• Progress in Medical Physics
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• v.9 no.1
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• pp.55-64
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• 1998

In recent, the demand of development of the high dose rate brachytherapy source increased for substitute for Co-60 source by iridium source, since the supplying Co-60 source is very depressed and the high dose rate brachytherapy sources are entirely imported from the abroad. This study investigated the exposure rates and isotropic dose distributions for the Ir-192 source produced from $\^$191/Ir(n,r)$\^$192/Ir by nuclear reactor in Korea Atomic Energy Research Institute. The activity of source was obtained an 1.012 Ci (the initial activity without encapsulation was 2,87Ci) by measurement with encapsuled stainless steel. The exposure rate of provided Ir-192 source was determined on 6.36 ${\pm}$ 0.147 Rm$^2$/h-GBq (2.350 ${\pm}$ 0.054 Rcm$^2$/mCi-hr) within ${\pm}$ 2.2% discrepancy with IC-10 ion chamber (0.14 cc) which was mounted on the acrylic jig to 5, 10 and 20 cm from the center of source. The calculated doses with 22 most significant spectrum lines were corrected with intrinsic efficiency of the germanium detector were compared to measured exposure dose rates within ${\pm}$3.8 % discrepancy. The authors confirmed the high dose rate Ir-192 source could be replaced the long decayed Co-60 source via investigation of the isotropic dose distributions in lateral, source axis and diagonal direction of source center are very closed to within 3% uncertainties. Especially, this exposure rate constant and isotropic dose distribution will be fundamental to build the high dose rate source and develop the computed therapy planning system.

• Progress in Medical Physics
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• v.23 no.4
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• pp.326-332
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• 2012

Recently, there are difficulties in operating brachtherapy machine in the radiotherapy department because of increasing the source price with decreasing nuclear reactor in the world. The development and technical features of the Ir-192 HDR sources (4.5 mm, 1.1 mm in diameter) in Korea were described in this report. We expect that this report will be helpful for hospitals to make the long-term plan for operating and managing HDR brachytherapy machine.

• Progress in Medical Physics
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• v.9 no.4
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• pp.259-266
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• 1998

To achieve the 2D dose distribution around the designed high dose rate Ir-192 source substitution for Co-60 brachytherapy source, we determined the exposure rate constant and tissue attenuation factors as a large depth as a 20 cm from source center. The exposure rate constant is used for apparent activity in designed source with self-absorption and encapsulation steel wall. The tissue dose delivered from the 4401 segments of 2.5 mm in a diameter and 2.5 mm height of disk-type source layer. In the experiments, the tissue attenuation factors include the tissue attenuation and multiple scattering in a medium surrounding the source. The fitted the polynomial regression with 4th order for the tissue attenuation factors are very closed to the experimental measurement data within ${\pm}$1% discrepancy. The Meisberger's constant showed the large uncertainty in large distance from source. The exposure rate constant 4.69 Rcm$^2$/mCi-hr was currently used for determination of apparent activity of source and air kerma strength was obtained 0.973 for tissue absorbed dose from the energy spectrum of Ir-192 source. In our experiments with designed high dose rate brachytherapy source, the apparent activity of Ir-192 source was delivered from the 54.6 % of actual physical source activity through the self-absorption and encapsulation wall attenuations. This paper provides the 2-dimensional dose tabulation from unit apparent activity in a water medium for dose planning includes the multiple scattering, source anisotropy effect and geometric factors.

• Journal of radiological science and technology
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• v.30 no.1
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• pp.33-38
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• 2007

The propose of this study is a verification of the correct calculation of the dose around source and the prescription dose of Ir-192 source in the plato treatment planning system. The source and orthogonal coordinates for lateral direction and those for the anterior posterior direction were drawn on a A4 paper and then input into the system. The prescription dose was prescribed to two points with radius 1 cm in the direction of polar angle $90^{\circ} and $270^{\circ} from the center of the source. The doses of prescription point and dose points acquired from the treatment planning system were compared with those from manual calculation using the geometry function formalism derived by Paul King et al. In this analysis, the doses of prescription point were exactly consistent with each other and those of dose points were obtained within the error point of 1.85%. And the system of accuracy was evaluated within 2% of tolerance error. Therefore, this manual dose calculation used for the geometry function formalism is considered to be useful in clinics due to its convenience and high quality assurance.

• Progress in Medical Physics
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• v.21 no.1
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• pp.78-85
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• 2010

The compatibility with GammaMed-12i brachytherapy machine for an Ir-192 encapsulated source (IRRS20, KAERI, Korea) manufactured by Korea atomic energy research institute (KAERI) has been investigated. As a mechanical testing of compatibility, precise measurement of step movement with channels, measurement of curvature of radius for wire, and emergency return testing were performed. Periodic measurements of air kerma strength for 45 days were carried out to evaluate decay characteristics of Ir-192 radioisotope and comparison of dose distributions in phantom between KAERI and old sources previously used were performed by film dosimetry. KAERI source has a good compatibility with GammaMed12i machine as a result of mechanical testing. There are in good agreement with calculated values in activity characteristics and there were small differences in dose distributions around the source in comparison between KAERI and old source.

• Journal of the Korean Society for Nondestructive Testing
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• v.28 no.1
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• pp.25-32
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• 2008

[ $^{169}Yb$ ] industrial NDT sealed sources were developed by using $Yb_2O_3$ pellets as the target and demonstrated for their performance. To produce the pellets, optimal compacting and sintering conditions were determined experimentally. Source holders for $^{169}Yb$ were designed and fabricated. After assembling an active source produced from HANARO with the developed source holder, a demonstration experiment was performed to compare the quality of the radiographs from $^{192}Ir$ and soft X-rays. This demonstration study showed that the developed $^{169}Yb$ produced better radiographs than $^{192}Ir$ for a carbon steel with less than a 4 mm thickness.

• Progress in Medical Physics
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• v.12 no.1
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• pp.19-29
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• 2001

In dose modeling, the shape of actual source and sealed capsule are important parameter to determine the physical dose computation. The author investigated the effect of filter of source self-absorption and sealed capsule to designed the high dose rate Ir-192 source for Ralstron(Japan) unit. The size of source designed to 1.5 mm $\Phi$ x 1.5mm length of actual source sealed with stainless steel which is 3.0mm $\Phi$ x 12.0mm length connected to driving cable. The dose attenuation was derived 66.3 % from 2655 segmented source at reference point of 10mm lateral distance of source. The output dose rate factor in tissue for designed source showed 0.0013511 cGy/mCi-sec in reference point at 1cm lateral distance of source center. The dose distribution at inferior of source showed the 52% of that of source tip region, however, the filtering effect was small as 4% at 45degrees of source axis. The dose attenuation within 20 degrees of source axis at near source-cable connector showed large filtering effect as 40% over, but the small effect was revealed isotropic dose distribution at large angle.

• 대한방사선방어학회:학술대회논문집
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• 2011.04a
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• pp.6-7
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• 2011