• Journal of the Korean Data and Information Science Society
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• v.23 no.1
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• pp.71-77
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• 2012

This paper introduces the projection methods by nonlinear regression model. To predict the student numbers, a log model and an involution model as the kind of a trend-extrapolation method are used. Empirical evidence shows that a projection by log model is better than by involution model with the confidence interval estimations for the coefficients of determination.

• Convergence Security Journal
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• v.23 no.5
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• pp.135-142
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• 2023

In addressing the prominent issues of climate change, resource scarcity, and environmental pollution associated with household waste, extensive research has been conducted on intelligent waste classification methods. These efforts range from traditional classification algorithms to machine learning and neural networks. However, challenges persist in effectively classifying waste in diverse environments and conditions due to insufficient datasets, increased complexity in neural network architectures, and performance limitations for real-world applications. Therefore, this paper proposes i-YOLOX as a solution for rapid classification and improved accuracy. The proposed model is evaluated based on network parameters, detection speed, and accuracy. To achieve this, a dataset comprising 10,000 samples of household waste, spanning 17 waste categories, is created. The i-YOLOX architecture is constructed by introducing the Involution channel convolution operator and the Convolution Branch Attention Module (CBAM) into the YOLOX structure. A comparative analysis is conducted with the performance of the existing YOLO architecture. Experimental results demonstrate that i-YOLOX enhances the detection speed and accuracy of waste objects in complex scenes compared to conventional neural networks. This confirms the effectiveness of the proposed i-YOLOX architecture in the detection and classification of multiple household waste objects.

• Childhood Kidney Diseases
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• v.10 no.1
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• pp.27-32
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• 2006

Purpose : Conservative management of multicystic dysplastic kidney(MCDK) without nephrectomy has recently been advocated. The purpose of this study was to determine the clinical course of conservatively managed MCDK and to find out possible predictive factors for involution of MCDK by ultrasonography(US). Methods : A retrospective analysis was made on 45 patients(26 boys and 20 girls) in whom MCDK was detected and had been traced by US between Dec. 1993 and Aug. 2005 at Severance Hospital. Results : Median follow-up time was 30 months(range 2-102 months). All patients under-went radionuclide scans and voiding eystourethrograms. The serial follow-up US showed complete involution in 11(24%), partial involution in 19(41%), and no interval change or increased in cyst size in 13(28%) patients. Nephrectomy was done in 3 patients(7%) due to relapsing urinary tract infection(UTI) and severe abdominal distension. The mean age of complete involution of MCDK was 37 months(range 12-84 months). Episodes of UTI were present in 17 patients(37%) and additional genitourinary(GU) abnormalities were found in 22 patients(44%). Hypertension and renal insufficiency was complicated in one patient. No child developed malignant tumor. Univariate analysis showed that five variables were associated with complete involution of the MCDK; gender, site, UTI episode, additional GU abnormalities, and renal length on initial US. After adjusting using the Pearson model, the presence of additional GU abnormalities was exclusively associated with complete involution among the 5 variables(P=0.034). Conclusion : In our review of 46 cases of MCDK, non-surgical approach for patients with MCDK was advisable and we could predict poor prognosis when MCDK is associated with other GU anomalies.

• Biomolecules & Therapeutics
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• v.6 no.3
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• pp.232-241
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• 1998

This study was done to investigate whether cholic acid derivatives have anti-stress activity in various stress models. Two cholic acid derivatives, ursodeoxycholic acid (UDCA) and tauroursodeoxycholic acid (WDCA), were used. physical, psychological, chemical and environmental stress models were performed. Adrenal weight, serum glucose levels and ALP activity were elevated in restraint stress model, but this elevation was prevented by UDCA treatment. Moreover, UDCA and TUDCA inhibited exploratory and spontaneous movements in oscillation stress model. In alcohol-induced stress model, TUDCA improved rotarod performance. UDCA and TUDCA significantly reduced the involution of lymphoid organs and the increment of WBC counts in cold stress model. These findings suggest that choric acid derivatives have antistress effects in various stress models.

• Journal of the Earthquake Engineering Society of Korea
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• v.23 no.2
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• pp.141-147
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• 2019

This research focuses on developing the Smart material with Grease adopted as a base oil to overcome a particle deposition caused by the MR fluid consisting of a silicon, which maximizing the characteristics and advantage of the MR fluid. By adopting the SMG fluid to a shear damper, this paper aimed to evaluate the control performance of it according to the variation of intensity of electric current(0 A, 0.5 A, 1.0 A, 1.5 A, 2.0 A, 2.5 A) and frequency(0.5 Hz, 1 Hz, 2 Hz). Subsequently, the usability of the SMG damper was analyzed by comparing the dynamic model of it to that of the other types of dampers(Power(Involution) Model, Bingham Model). As a result, DR, the performance indicator of semi-active damper, shows approximately 5 in a condition of 2 Hz. Also while confirming the excellent performance like the Power and the Bingham model, it raises the possibility to exploit it as the semi-active damper.

• Journal of Life Science
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• v.19 no.8
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• pp.1067-1072
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• 2009

Stromal derived factor-1 (SDF-1 or CXCL12), one of the CXC chemokines, is widely expressed in many tissues, including the thymus. The thymus can regenerate to its normal mass within 14 days after acute involution induced by cyclophosphamide (CY) in adult rats. Despite the established role of SDF-1 signaling in the development of T and B lymphocytes in the thymus, it has not yet been associated with the regeneration of the adult thymus. The purpose of this study was to investigate whether SDF-1, which is expressed in thymic stromal cells, is modulated during thymic regeneration in adult rats. Here, we showed that SDF-1 mRNAs were expressed in high levels in the thymocyte and thymic stromal cells at day 7 of the CY model. SDF-1 protein was shown to be present at the cortex-medulla junction, paraseptum and within the thymic medulla. Double-immunofluorescence for SDF-1 and ED-1 showed that strong SDF-1 expression was detected in the macrophages of the medulla region displaying immunoreactivity for ED-1 during thymus regeneration. Taken together, our results demonstrated that SDF-1 expression increased in regenerating thymic macrophages, suggesting the roles of SDF-1 as a chemo-attractant for damaged cells produced in the process of thymic regeneration after acute involution induced by CY.

• Development and Reproduction
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• v.5 no.2
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• pp.175-180
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• 2001

The ectopic expression of gonadotropin releasing hormone(GnRH and luteinizing hormone(LH) in several tissues is a quite intriguing phenomenon. Recently, the presence of GnRH and its receptor has been clearly demonstrated in rodents and human mammary gland. In this context, one can postulate that the presence of local circuit composed of GnRH and LH in the gland. The present study was undertaken to elucidate whether there is a correlation between the LH expression in rat mammary gland and physiological status during the process of mammary differentiation. LH contents in mammary gland from cycling to weaning rats were measured by radioimmunoassay(RIA). In cycling rats, changes of the LH level in both serum and mammary gland showed similar pattern as the highest level in proestrus and the lowest level in diestrus II stage. While the serum LH levels were fluctuated from pregnant through involution stage, a sharp decline of mammary LH contents was observed in the lactating rats. This decrement was recovered in involuting rats to the level of proestrus stage. Reverse transcription-polymerase chain reaction (RT-PCR) and Southern blot analyses demonstrated that the transcriptional activities of the mammary LH and GnRH were increased from diestrus I stage to estrus stage, and the increased levels were maintained in pregnant, lactation and involution stages. To test the hypothesis that the alteration in mammary LH expression might be steroid-dependant, ovariectomy(OVX) and steroid supplement model was employed. As expected, supplement of estradiol(E$_2$) after OVX remarkably decreased serum LH level compared to that in serum from vehicle-only treated rats. Likewise, administration of E$_2$ significantly reduced the mammary LH content. The present study demonstrated that (i) the LH expression in mammary gland could be altered by some physiological parameters such as estrous cycle, pregnancy, lactation and involution, and (ii) ovarian steroid especially estrogen seems to be one of major endocrine factors which are responsible for regulation of mammary LH expression.

• Journal of the Korean GEO-environmental Society
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• v.13 no.5
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• pp.13-24
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• 2012

In this study, the in-situ model test has been conducted and used to estimate and analyze consolidation behavior of the ground by using the miniature test that reconstructs economically geotechnical behavior of in-situ full scale structure. To analogize the relation among effective stress, void ratio and coefficient of permeability at the self-weight consolidation stage, the low stress seepage consolidation test has been conducted and the involution function of constitutive equation had been obtained from the result of the curve fitted seepage consolidation test result. As a result of the numerical analysis that had been conducted on the representative section using a constitute equation, final settlement was similar with those of self-weight consolidation of the centrifugal model test. But, it was more or less smaller. It seems that these trends are caused by the difference between estimated values.

• Journal of the Korean Geotechnical Society
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• v.24 no.10
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• pp.45-55
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• 2008

In this study, the in-situ model test has been conducted to estimate and analyze consolidation behavior of the ground by using the miniature test that reconstructs economically geotechnical behavior of in-situ full scale structure. To analyze the relation of effective stress, void ratio and coefficient of permeability at the self-weight consolidation stage, the low stress seepage consolidation test has been conducted and the involution function of constitutive equation had been obtained from the result of the curve fitted seepage consolidation test. As a result of the numerical analysis that had been conducted on the representative section using a constitute equation, final settlement was similar to those of self-weight consolidation of the centrifugal model test. But it was more or less smaller. It seems that these trends are caused by the difference between estimated values.

• IMMUNE NETWORK
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• v.16 no.4
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• pp.242-248
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• 2016

Thymic atrophy is a complication that results from exposure to many environmental stressors, disease treatments, and microbial challenges. Such acute stress-associated thymic loss can have a dramatic impact on the host's ability to replenish the necessary naïve T cell output to reconstitute the peripheral T cell numbers and repertoire to respond to new antigenic challenges. We have previously reported that treatment with the orexigenic hormone ghrelin results in an increase in the number and proliferation of thymocytes after dexamethasone challenge, suggesting a role for ghrelin in restraint stress-induced thymic involution and cell apoptosis and its potential use as a thymostimulatory agent. In an effort to understand how ghrelin suppresses thymic T cell apoptosis, we have examined the various signaling pathways induced by receptor-specific ghrelin stimulation using a restraint stress mouse model. In this model, stress-induced apoptosis in thymocytes was effectively blocked by ghrelin. Western blot analysis demonstrated that ghrelin prevents the cleavage of pro-apoptotic proteins such as Bim, Caspase-3, and PARP. In addition, ghrelin stimulation activates the Akt and Mitogen-activated protein kinases (MAPK) signaling pathways in a time/dose-dependent manner. Moreover, we also revealed the involvement of the FoxO3a pathway in the phosphorylation of Akt and ERK1/2. Together, these findings suggest that ghrelin inhibits apoptosis by modulating the stress-induced apoptotic signal pathway in the restraint-induced thymic apoptosis.