• 지구물리와물리탐사
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• 제16권4호
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• pp.211-216
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• 2013

일반적으로 평활화 필터는 주변값들과의 차이를 감소시켜 함수를 정규화하는 역할을 한다. 따라서 완전파형역산에 평활화 필터를 적용하면 역산 해를 정규화 할 수 있으며 실제 지하 구조에 가까운 영상을 얻을 수 있다. 다만 단일 평활화 계수를 사용했을 때는 지층 형태나 속도변화에 관계없이 동일하게 평활화가 이루어지므로 지층간 경계면이나 단층 등의 구조가 불명확해지는 단점이 있다. 본 논문에서는 이러한 문제를 해결하기 위해 단일 평활화 계수가 아닌 역산 반복 과정에 따라 선택적으로 평활화 계수를 조정하는 정규화 기법을 개발하였다. 먼저 파형역산에 적합한 탐사자료의 주파수 대역과 그에 대응하는 파수 범위를 분석하였다. 분석한 파수 범위에 적합한 평활화 계수를 선정하기 위해 평활화 필터의 파수 스펙트럼에서 99백분위수에 해당하는 파수를 유효최대파수로 결정하였다. 선정된 평활화 계수를 반복역산에 따라 다르게 적용하여 여러 주파수를 동시에 이용하는 멀티-스케일 완전파형역산을 구현하였다. 암염 모델과 같은 속도대비가 큰 지질구조에 대해 성공적인 역산결과를 얻음으로써 본 연구에서 개발한 평활화 계수 선택기법이 효과적인 정규화 과정을 구현한다는 것을 알 수 있었다. 또한 무작위 잡음이 더해진 인공합성 음원모음 자료에 대한 수치예제를 통해 현장 자료에 대한 적용 가능성도 확인할 수 있었다.

• Nutrition Research and Practice
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• 제8권4호
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• pp.453-462
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• 2014

BACKGROUND/OBJECTIVES: The inverse relationships of combined fruits and vegetables intake with blood pressure have been reported. However, whether there are such relationships with salty vegetables has rarely been investigated in epidemiologic studies. We evaluated the relation of combined and separate intake of fruits, vegetable intakes, and salty vegetables, as well as sodium and potassium, with blood pressure among the middle-aged and elderly populations. SUBJECTS/METHODS: The present cross-sectional analysis of a prospective cohort baseline survey was performed with 6,283 subjects (2,443 men and 3,840 women) and free of hypertension, diabetes, cardiovascular diseases, and cancer. Dietary data were collected by trained interviewers using food frequency questionnaire. RESULTS: The significantly inverse linear trend of diastolic blood pressure (DBP) was found in fruits and non-pickled vegetables (81.2 mmHg in the lowest quintile vs 79.0 mmHg in the highest quintile, P for trend = 0.0040) and fruits only (80.9 mmHg in the lowest quintile vs 79.4 mmHg in the highest quintile, P for trend = 0.0430) among men. In contrast, sodium and sodium to potassium ratio were positively related with blood pressure among men (DBP, 78.8 mmHg in the lowest quintile vs 80.6 mmHg in the highest quintile, P for trend = 0.0079 for sodium; DBP, 79.0 mmHg in the lowest quintile vs 80.7 mmHg in the highest quintile, P for trend = 0.0199 and SBP, 123.8 mmHg in the lowest quintile vs 125.9 mmHg in the highest quintile for sodium/potassium). Kimchies consumption was positively related to DBP for men (78.2 mmHg in the lowest quintile vs 80.9 mmHg in the highest quintile for DBP, P for trend = 0.0003). Among women, these relations were not found. CONCLUSION: Fruits and/or non-pickled vegetables may be inversely, but sodium, sodium to potassium, and Kimchies may be positively related to blood pressure among men.

• Korean Journal of Radiology
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• 제25권2호
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• pp.166-178
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• 2024

Objective: This study aimed to determine the predictive performance of non-contrast CT (NCCT) signs for hemorrhagic growth after intracerebral hemorrhage (ICH) when stratified by onset-to-imaging time (OIT). Materials and Methods: 1488 supratentorial ICH within 6 h of onset were consecutively recruited from six centers between January 2018 and August 2022. NCCT signs were classified according to density (hypodensities, swirl sign, black hole sign, blend sign, fluid level, and heterogeneous density) and shape (island sign, satellite sign, and irregular shape) features. Multivariable logistic regression was used to evaluate the association between NCCT signs and three types of hemorrhagic growth: hematoma expansion (HE), intraventricular hemorrhage growth (IVHG), and revised HE (RHE). The performance of the NCCT signs was evaluated using the positive predictive value (PPV) stratified by OIT. Results: Multivariable analysis showed that hypodensities were an independent predictor of HE (adjusted odds ratio [95% confidence interval] of 7.99 [4.87-13.40]), IVHG (3.64 [2.15-6.24]), and RHE (7.90 [4.93-12.90]). Similarly, OIT (for a 1-h increase) was an independent inverse predictor of HE (0.59 [0.52-0.66]), IVHG (0.72 [0.64-0.81]), and RHE (0.61 [0.54-0.67]). Blend and island signs were independently associated with HE and RHE (10.60 [7.36-15.30] and 10.10 [7.10-14.60], respectively, for the blend sign and 2.75 [1.64-4.67] and 2.62 [1.60-4.30], respectively, for the island sign). Hypodensities demonstrated low PPVs of 0.41 (110/269) or lower for IVHG when stratified by OIT. When OIT was ≤ 2 h, the PPVs of hypodensities, blend sign, and island sign for RHE were 0.80 (215/269), 0.90 (142/157), and 0.83 (103/124), respectively. Conclusion: Hypodensities, blend sign, and island sign were the best NCCT predictors of RHE when OIT was ≤ 2 h. NCCT signs may assist in earlier recognition of the risk of hemorrhagic growth and guide early intervention to prevent neurological deterioration resulting from hemorrhagic growth.

• Journal of Nutrition and Health
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• 제37권7호
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• pp.550-556
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• 2004

Dietary pattern analysis is important complementary approach for identifying associations between diet and chronic disease. A case-control study was conducted in order to examine dietary patterns and the risk of colon cancer in Korea. Data were collected from both 137 cases with either colorectal cancer or large bowl adenomatous polyps and 134 controls regarding social-demographic characteristics and food intake using a semi-quantitative food frequency questionnaire. We conducted factor analysis and identified 6 major dietary patterns: 'Well-being diet' characterized by higher intakes of potatoes, yogurt, soybean paste and vegetables, 'Meat & fish', 'Milk & juice', 'Pork & alcohol', 'Rice & kimchi', and 'Coffee & cake'. We calculated factor scores for each participant and examined the associations between dietary patterns and colon cancer risk. After adjusting for potential confounders, there was a relative risk for colon cancer of 0.16 (95% confidence interval, 0.07 - 0.34) when comparing the highest with the lowest tertile of the 'Well-being' pattern. Significant trends of decreasing risk of colon cancer also emerged with the 'Milk & juice' (OR = 0.40, 95% CI = 0.20 - 0.79). In contrast, inverse associations of the risk were found for 'Pork & alcohol' (OR = 1.92, 95% CI = 0.93 - 3.97), 'Coffee & cake' (OR = 2.18, 95% CI = 1.07 - 4.46). For the 'Meat & fish' pattern, the decreased risk of colon cancer was observed in the second tertile, but not in the highest tertile when comparing to the lowest. The 'Rice & kimchi' pattern had a nonsignificant association with the risk. These data suggest that major dietary patterns derived from the FFQ associated with the risk of colon cancer in Korea. Since foods are not consumed in isolation, dietary pattern research in natural eating behavior may be useful for understanding dietary causes of colon cancer.

• 미생물학회지
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• 제40권2호
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• pp.115-120
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• 2004

시안세균(Anabaena cylindrica)의 생장을 효과적으로 억제하는 세균을 분리하여 NG-2로 구분하였다. 이 세균은 그람 음성의 막대형 세균으로서 1.3∼$1.8{\times}0.35{\mu}m$ 정도의 크기를 보였으며, 카탈라제와 옥시다제 양성 반응을 나타내었고, 35∼$40^{\circ}C$아 pH 9.0의 적정생장 조건을 보였다. A.cylindrica의 NG-2를 JM 배지에서 혼합배양할 경우 두 미생물군은 서로 반비례적으로 성장하였으며, 24시간 이내에 A. cylindrica의 영양세포가 거의 완전히 소멸하였다. NG-2는 빛이 있는 조건에서만 효과적으로 A. cylindrica를 분해하였는데, 이는 NG-2의 A. cylindrica 분해활성이 숙주의 광합성 작용에 매우 의존적임을 의미한다. 분리세균의 A. cylindlica 분해작용을 현미경으로 관찰한 결과 NG-2는 숙주세포에 부착하지 않고 배지 내에 산재한 상태에서 영양세포를 분해하였으며, 이형세포는 분해되지 않았다. 또한 영양세포의 세포벽이 분해되면 분해세균들이 filament 주위에 집중적으로 부착하는 콜로니를 형성함으로써 A. cylindrica를 완전히 분해하는 것이 확인되었다. A. cylindrica에 대한 NG-2의 분해활성은 인공배지 뿐만 아니라 강물에서도 유사한 결과를 나타내었다. 또한 발포 polystyrene 재질의 bead에 세균을 부착함으로써 A. cylindrica 분해 효율을 더 상승시킬 수 있었다.

• Asian Pacific Journal of Cancer Prevention
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• 제17권8호
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• pp.4131-4136
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• 2016

Background: The population in northeast Thailand continues to present with hepatobiliary abnormalities, particularly periductal fibrosis (PDF) which is the result of chronic infection with liver fluke (Opisthorchis viverini; OV) and may lead to the development of cholangiocarcinoma (CCA). Although the prevalence of OV infection has been decreased due to a liver fluke control program over decades, the prevalence of PDF remains high. This study aimed to investigate demographic factors associated with PDF risk based on ultrasonography (US) screening. Materials and Methods: This cross-sectional study is part of the Cholangiocarcinoma Screening and Care Program (CASCAP), a prospective cohort study. Multiple logistic regression was used for data analysis. Results: In 55,246 subjects, the overall prevalence of PDF was 33.0% (95%CI: 32.6 - 33.4). Males (33.9 %) were at higher risk for developing PDF than females (32.2 %) (ORcrude = 0.93; 95%CI: 0.89 - 0.96; p-value < 0.001). Factors associated with an increased PDF risk, in addition to OV infection, included old age (${\geq}70$ years) (ORadj = 1.28, 95% CI: 1.14 - 1.44, p < 0.001) and hepatitis B infection (ORadj = 1.31, 95% CI: 1.11 - 1.55, p = 0.001). In contrast, number of praziquantel treatments (> 2 times) (ORadj = 0.54, 95% CI: 0.47 - 0.63, p < 0.001) and diabetes mellitus (ORadj = 0.57, 95% CI: 0.49 - 0.65, p < 0.001) were significantly associated with a decreased PDF risk. Conclusions: Future US screening should closely examine older people and hepatitis B subjects for the purpose of PDF surveillance among high risk groups for CCA. However, the results of inverse associations require further investigation in order to confirm our findings.

• Asian Pacific Journal of Cancer Prevention
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• 제15권2호
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• pp.623-627
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• 2014

Background: Esophagus cancer (EC) is among the five most common cancers in both sexes in Iran, with an incidence rate well above world average. Social rank (SR) of individuals and regions are well-known independent predictors of EC incidence. The aim of current study was to assess gender and social disparities in EC incidence across Iran's provinces through 2003-2009. Materials and Methods: Data on distribution of population at province level were obtained from the Statistical Centre of Iran. Age-standardized incidence rates of EC were gathered from the National Cancer Registry. The Human Development Index (HDI) was used to assess the province social rank. Rate ratios and Kunst and Mackenbach relative indices of inequality ($RII_{KM}$) were used to assess gender and social inequalities, respectively. Annual percentage change (APC) was calculated using joinpoint regression. Results: EC incidence rate increased 4.6% and 6.5% per year among females and males, respectively. There were no gender disparities in EC incidence over the study period. There were substantial social disparities in favor of better-off provinces in Iran. These social disparities were generally the same between males and females and were stable over the study period. Conclusions: The results showed an inverse association between the provinces' social rank and EC incidence rate in Iran. In addition, I found that, in contrast with international trends, women are at the same risk of EC as men in Iran. Further investigations are needed to explain these disparities in EC incidence across the provinces.

• 한국대기환경학회지
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• 제34권1호
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• pp.156-165
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• 2018

Long-term trend analysis on air pollutant concentrations is very important to diagnose the present status and plan for the future. In this study, the long-term trends of $PM_{2.5}$ concentrations were estimated based on the relationship between the visibility and $PM_{2.5}$ concentration regarding the effects of relative humidity in Seoul and Chuncheon. The relationships between the visibility and $PM_{2.5}$ concentration were derived from the measurement data in 2015 and 2016. Then, the annual trends of $PM_{2.5}$ concentration from 1982 to 2014 were estimated and compared to those of $PM_{10}$ concentration available in Seoul and Chuncheon. During the estimation process, four ranges of relative humidity were considered such as less than 30%, 31~50%, 51~70%, and 71~90%. In Seoul and Chuncheon, the visibility and $PM_{2.5}$ concentration generally have the inverse relationship while the visibility decreases as the relative humidity increases. The estimated $PM_{2.5}$ concentrations similarly showed the decreasing tendencies from 2006 to 2012 in Seoul and Chuncheon. However, the estimated $PM_{2.5}$ concentrations showed the increasing tendency before 2005 in Chuncheon in contrast to the decreasing tendency in Seoul. This implies that the long-term trends of $PM_{2.5}$ concentration in different cities in South Korea reflect the local influencing factors. For example, 'Special Act on the Improvement of Atmospheric Environment in the Seoul Metropolitan Area' can affect the different long-term trends in Seoul and Chuncheon. The estimated $PM_{2.5}$ concentrations were validated with the measured ones in Seoul and Chuncheon. While the general tendencies were well matched between the estimated and measured concentrations, the $PM_{2.5}$ concentration trends in 1990s and their monthly variations are needed to be improved quantitatively using more reference data for longer years.

• 한국컴퓨터정보학회논문지
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• 제15권2호
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• pp.109-117
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• 2010

디지털 워터마킹은 불법 복제로부터 디지털 콘텐츠를 보호하기 위해 광범위하게 주목을 받아왔다. 본 논문은 디지털 오디오의 저작권 보호를 위해 주파수 영역에서의 새로운 워터마킹 구조를 제안한다. 제안하는 워터마킹 시스템에서는 디지털 오디오가 중첩되지 않는 프레임들로 분리된다. 분리된 각 프레임의 크기 대역에서 선택된 최고치에 워터마크가 삽입된다. 모의실험 결과, 제안하는 방법은 노이즈 추가, 잘라내기, 재배열, 양자화, MP3 압축, 저역통과 필터 등과 같은 공격에서 강인성을 보인다. 제안한 방법의 이러한 결과는 잘 알려진 Cox방법과 비교하여 유사한 강인성을 보이지만, SNR 측면에서는 Cox방법보다 우수한 성능을 보였다. 제안한 방법은 20dB에서 28dB의 SNR을 보인반면, Cox방법은 단지 14dB에서 23dB의 성능을 보였다.

• 한국전자파학회논문지
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• 제26권4호
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• pp.397-403
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• 2015

본 논문은 임펄스 초광대역 레이다를 이용한 ISAR 영상의 기하보정 방법에 대해 서술하였다. 임펄스 초광대역 레이다는 시간영역에서 신호처리를 하므로 다중 경로, 간섭 문제 등이 일어나지 않는 장점이 있다. 안테나와 대상체 사이의 송수신 신호를 평면파라고 가정하면, ISAR 기하 모델에서 회전축의 중심을 점표적을 이용하여 계산한다. 수신 데이터에서 합성을 수행하기 전, 점표적은 최대 점의 위치를 최소 자승법으로 근사하여 회전축의 중심을 알아낼 수 있다. 이 방법은 대조비가 더 뛰어난 영상을 얻을 수 있었고, 엔트로피도 가장 큰 값을 가질 수 있었다. 이러한 방법은 장비를 최초 작동하거나 주기적으로 사용되어서 회전축의 중심을 보상하여 영상 합성을 할 것이다. 의료나 보안 감시와 같은 고정된 기하를 가지는 영상화 장비에서 유용하게 사용될 것이다.