• Title/Summary/Keyword: Introduction to Medicine

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The change of air lead concentrations in litharge making and smelting industries (일부 제련 및 리사지 사업장에서 공기중 납 노출농도의 변화)

  • Choi, Jae-Wook;Kim, Nam-Soo;Cho, Kwang-Sung;Ham, Jung-O;Lee, Byung-Kook
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.20 no.1
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    • pp.10-18
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    • 2010
  • To provide necessary information for future environmental monitoring of smelting and litharge making industries in Korea, environmental monitoring dataset of air lead concentration of 4 lead industries(1 primary smelting, 2 secondary smelting and 1 litharge making industry) were analyzed from 1994 to 2007. Data were compared using geometric mean and standard deviation with minimum and maximum values according to year of measurement, type of lead industries and type of operation of lead industries. The geometric mean and standard deviation of air concentration for a total of 1140 samples in all lead industries for overall 14 years were 70.7${\mu}g/m^3$ and 5.51 with minimum of 1${\mu}g/m^3$ and maximum of 9,185 ${\mu}g/m^3$. The overall geometric means of air concentration were above the permissible exposure levels(PEL) until year of 2001 and thereafter they were remained at the level of half of PEL. The geometric means of primary smelting, secondary smelting and litharge making industry for overall 14 years were 21.7${\mu}g/m^3$(number of samples: 353), 82.5${\mu}g/m^3$(number of samples: 357) and 164.2 ${\mu}g/m^3$(number of samples: 430) respectively. In primary smelting industry, the highest geometric mean air concentration was 35.4 ${\mu}g/m^3$ in the secondary smelting operation; followed by casting operation (24.9 ${\mu}g/m^3$) and melting operation (14.9 ${\mu}g/m^3$), respectively. On the other hand, in secondary smelting industries, the highest geometric mean air concentration was 125.4${\mu}g/m^3$ in melting operation; followed by casting operation (90.5${\mu}g/m^3$) and pre-treatment operation (43.4${\mu}g/m^3$), respectively. However, in litharge making industries, there were no significant differences of geometric mean air concentrations between litharge operation and stabilizer operation. The proportion of over PEL (50${\mu}g/m^3$) was highest in litharge industry and followed by secondary smelting industries. However The proportions of over PEL(${\mu}g./m^3.$) were decreased by the years of environmental monitoring. The significant reduction of mean air lead concentration since year of 2000 was observed due to more active environmental engineering control and new introduction of new operation in manufacturing process, but may be also influenced by non-engineering method such as reduction of operation hours or reduction of exposure time during actual environmental measurement by industrial hygienist according to more strict enforcement of occupational and safety law by the government.

Evaluation of the feasibility of bony window repositioning without using a barrier membrane in sinus lateral approach (상악동측방접근법시 차폐막을 사용하지 않는 골창재위치술의 유용성 평가)

  • Jeon, Seung-Hwan;Cho, Yong-Seok;Lee, Byung-Ha;Im, Tae-Yun;Hwang, Kyung-Gyun;Park, Chang-Joo
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.37 no.2
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    • pp.122-126
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    • 2011
  • Introduction: In the lateral window approach for a maxillary sinus bone graft, there has been considerable controversy regarding the placement of a barrier membrane over the osteotomy site. In particular, when there is no damage to the Schneiderian membrane, clinicians should decide whether to use a barrier membrane or not, considering the benefits and costs. This study presents the clinical cases to demonstrate that only repositioning the detached window can lead to satisfactory bony healing of the grafted material without using a barrier membrane in the lateral approach for a maxillary sinus bone graft. Materials and Methods: Five consecutive patients were treated with the same surgical procedures. After performing the antrostomy on the lateral maxillary wall using a round carbide bur and diamond bur, the bony window was detached by a gentle levering action. After confirming no perforation of the Schneiderian membrane, the grafting procedure was carried out the detached window of the lateral maxillary wall was repositioned over the grafted material without using a barrier membrane. A gross examination was carried out at the postoperative 6 month re-entry, and the the preoperative and postoperative dental computed tomography (CT) at re-entry were compared. Results: All the procedures in the 5 patients went on to uneventful healing with no complications associated with the bone graft. Satisfactory bone regeneration without the interference of fibrous tissue on the gap between the repositioned window and lateral wall of the maxillary sinus was observed in the postoperative 6 month re-entry. The CT findings at re-entry revealed the, reconstruction of the external cortical plate including repositioned bony window. In addition, the loss of the discontinuity of the lateral maxillary wall was confirmed. Conclusion: This preliminary report showed that the detached window, which was just repositioned on the grafted material, could function as a barrier membrane in the lateral approach for a maxillary sinus bone graft. Therefore additional morphometric and histologic studies will be needed.

An analysis of Web Sites on the Nursing Departments for Hospital Internet Marketing (병원의 인터넷 마케팅을 위한 간호부서의 웹사이트 분석)

  • Jung, Myun-Sook
    • Journal of Korean Academy of Nursing Administration
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    • v.7 no.3
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    • pp.531-543
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    • 2001
  • Purpose : The purpose of this study was exploring current status of having home page on the hospitals which have more than 500 beds and analyzing web site on the Nursing Department among them. Method : Cases under analyzing were 92 hospitals which have their own home pages. And then, content analysis with 33 cases was used to evaluate web site of Nursing Department. Results : 1. There are 85(92.4%) home pages in the hospitals among 92 hospitals. 2. There are 33(35.9%) web pages on the Nursing Home page in the 85 hospitals which has hospital home pages. 3. The contents of web pages were 'Introduction of Nursing Department' (78.8% of Nursing Department), 'Home health care'(39.4%), 'Areas of Nursing department'(36.4%), 'Educational Opportunities'(36.4%), 'Research activities'(30.3%), 'Interaction'(27.3%), 'E-mail'(18.2%), 'Information providing to consumer'(15.2%), 'Hospice'(15.2%), 'Hot line, consultation'(12.1%) respectively. Conclusion : The results showed that most web sites of Nursing Department were consist of simple contents with simple purpose. Therefore, in this informational world, Nursing Departments have to try using internet marketing with well developed client centered web site.

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Efficacy and effectiveness of pneumococcal conjugate vaccine in children (폐구균 단백 결합 백신의 효능 및 효과)

  • Lee, Hoan Jong
    • Clinical and Experimental Pediatrics
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    • v.49 no.3
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    • pp.235-241
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    • 2006
  • Streptococus pneumoniae is an important cause of invasive infections as well as non-invasive infections such as acute otitis media and sinusitis both in children and adults. Resistance of S. pneumoniae to multiple antimicrobials is increasing and poses therapeutic challenges, and prevention became more important. 23-valent polysaccharide vaccine has been used for the last several decades, but is not effective in children <2 years of age, the highest risk group of invasive diseases. Recently, a 7-valent pneumococcal protein conjugate vaccine(PCV) which is effective in infants and young children has been developed. The efficacy of PCVs against invasive pneumococcal disease and pneumonia is well established and is documented in several well-conducted studies. However, the effect of PCVs on otitis media is less obvious and more complex. PCVs clearly reduce diseases caused by vaccine-type(VT) pneumococci, but replacement of VT serotypes by non-VT serotypes in nasopharyngeal carriage of S. pneumoniae is responsible for the increase in acute otitis media caused by non-VT serotypes. Three years after introduction of PCV in the US, some increase of invasive infections with serotype 19A possibly due to serotype switching within certain vaccine type strains has been noted. Since most antibiotic-resistance in S. pneumoniae is confined to VT serotypes, vaccine use also reduces antibiotic resistance. With development of PCV, there was a great advance in the prevention of pneumococcal diseases, but replacement with potential virulent organisms and development of antibiotic resistance in non-VT pneumococci is a possibility that needs careful monitoring.

A Study on Clothing of American Indian (아메리칸 인디안(American Indian) 복식에 관한 연구)

  • 이숙희
    • Journal of the Korean Society of Clothing and Textiles
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    • v.18 no.3
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    • pp.368-386
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    • 1994
  • The primary purpose of this study was to identify the diversity and embellishment of American Indian clothing and relationship between culture and clothing in American Indian Culture Areas. After the introduction of European material culture, change in American Indian clothing was conducted. The result of the Study as follows: 1. The most influential factors affecting the diversity of American Indian clothing were environmental factors. Climates and geographical features, Raw material were reflected in clothing style and clothing material in each culture Area. 2. Economic situation and life style were shown to be influential to clothing development. The best known instance of this was greatly elaborated clothing and personal adornment of the Plains who had higher stand of life and nomadic life style. 3. Religious concepts were important factors influencing American Indian clothing. Indian tribes had different ritual performance they used particular motifs in clothing. Clothing, such as "ghost shirt", Apache medicine shirt and Pueblo ceremonial clothing, served hidden pur- poses. 4. Techenology was another factor identified in this study as influencing American Indian clothing. Especially, weaving skills of Southwest played a great role in textile development. Pueblo "manta" and Navaho "bil" were famous for Indian costume. 5. European material culture allowed great change of traditional native Indian clothing. American Indian had new material, new styles, new concept of clothing. 6. American Indian, although Indian applicated European trade goods, was actually quite conservative in retaining traditional designs and modes of decoration. Asthetics and traction of American Indian were reflected in American Indian clothing.d in American Indian clothing.

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Utilization of lacZ to Isolate Regulatory Genes from Corynebacterium glutamicum

  • KIM, HYUNG-JOON;JOON-SUNG PARK;HEUNG-SHICK LEE;YOUNHEE KIM
    • Journal of Microbiology and Biotechnology
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    • v.12 no.2
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    • pp.336-339
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    • 2002
  • A total of 100 Corynebacterial clones exerting a regulatory effect on the aceB promoter of Corynebacterium glutamicum were isolated by utilizing a reporter carrying the enteric lacZ gene fused to the promoter. The isolated clones were classified into 3 groups of A, B, and C, according to their color of colonies. Escherichia coli cells carrying clones in groups A and B showed a $90\%\;and\;50\%$ reduction in ${\beta}$-galactosidase activity, respectively. The introduction of group A clones into C. glutamicum also resulted in an almost complete reduction in the expression of the aceA and aceB genes, suggesting that the clones express repressor-like proteins for the genes. Although white colonies were formed on plates containing X-gal, E. coli cells carrying one of the clones in group C exhibited intact ${\beta}$-galactosidase activity. The result suggests that the clone may encode proteins that prevent the cells from accumulating the chromogenic compound, X-gal.

Electron Microscopic Studies of Human Keloid and Hypertrophic Scars (Keloid와 Hypertrophic Scar ( 비후성반흔 )의 형태학적 관찰)

  • Kim, Chung-Soak;Lew, Jae-Duk
    • Applied Microscopy
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    • v.3 no.1
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    • pp.29-38
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    • 1973
  • Introduction. The human cutaneous scars manifest themselves many ways in different types according to the factors such as the age, sex, race of the patient as well as the location,. kind and heal ing process of the wound. Among the scars it is quiet difficult to verify the clinical course of the hypertrophic or keloidal scars from the true keloids. However, clinical observations indicate that stress, either mechanical or in the forms of chronic infections, can induce a functional change in the fibroblasts causing an excessive production of collagenous matrix. In this study, we preliminary attempt to justify any difference of the cellular structure between keloids and hypertrophic scars by using electron microscope. Material and Methods. A total of 23 cases: 2 scars, 2 hypertrophic scars and 19 keloids are examined. Immediately, the biopsy tissue was fixed in 10% neutral formalin and 4% glutaraldehyde solution in phosphate buffer for 4 hours, post fixed in 1 % osmium tetraoxide for two hours, dehydrated with graded alcohol, and embedded in Epon 812. Thick sections were stained with hematoxylin eosin, periodic acid-Schiff(PAS) and Van Gieson stain. Thin sections were cut and uranyle acetate, lead citratestain and examined with the electron microscope. Result. The morphologic features of keloid showed thick, homogenously eosinophilic bands of collagen and numberous large active fibroblasts. The hypertrophic scar and soft scar are more cellular than keloid and composed thinner collagenous fiber. For this paper in the etiology of keloids can not as be defined, but and interesting keloidal tissue fibroblast showed irregular nucleus with irregular shape dense bodies and fibril materials contained in to the cytoplasm.

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Factors Related to Perceived Life Satisfaction Among the Elderly in South Korea

  • Jung, Min-Soo;Muntaner, Carles;Choi, Man-Kyu
    • Journal of Preventive Medicine and Public Health
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    • v.43 no.4
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    • pp.292-300
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    • 2010
  • Objectives: This study attempted to explore the aging phenomena that now characterize much of Korean society, and assessed issues associated with the life satisfaction experienced during the process of aging. Methods: By employing the National Survey on the State of Life and the Desire for Welfare of the Elderly, 2004 in South Korea this study attempted to identify the factors that determine subjective life satisfaction among the elderly. The data utilized herein consisted of 3278 elderly people aged 65 years or older, from 9308 households. Results: The results of analysis from the final model after the introduction of 19 variables in 8 factors showed statistically similar explanatory power in men (adj. $R^2=0.320$) and in women (adj. $R^2=0.346$). We found that economic condition was the most influential factor in both men (B = 0.278) and women (B = 0.336) except perceived health condition variables. The second most influential variable in life satisfaction was health checkups in men (B = 0.128) and degree of nutritional diet in women (B = 0.145). Those who had experience with chronic diseases also reported significantly lower perceived life satisfaction and this was particularly true of women. Conclusions: The aging society requires an understanding of the lives of elderly individuals. This study explored factors associated with life satisfaction in old age by using a life satisfaction model. The success of an aging society begins with an accurate understanding of the elderly, and thus political attention will need to be focused on this matter.

Who are the Breast Cancer Survivors in Malaysia?

  • Ibrahim, Nor Idawaty;Dahlui, M.;Aina, E.N.;Al-Sadat, N.
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.5
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    • pp.2213-2218
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    • 2012
  • Introduction: Worldwide, breast cancer is the commonest cause of cancer death in women. However, the survival rate varies across regions at averages of 73%and 57% in the developed and developing countries, respectively. Objective: This study aimed to determine the survival rate of breast cancer among the women of Malaysia and characteristics of the survivors. Method: A retrospective cohort study was conducted on secondary data obtained from the Breast Cancer Registry and medical records of breast cancer patients admitted to Hospital Kuala Lumpur from 2005 to 2009. Survival data were validated with National Birth and Death Registry. Statistical analysis applied logistic regression, the Cox proportional hazard model, the Kaplan-Meier method and log rank test. Results: A total of 868 women were diagnosed with breast cancer between January 2005 and December 2009, comprising 58%, 25% and 17% Malays, Chinese and Indians, respectively. The overall survival rate was 43.5% (CI 0.573-0.597), with Chinese, Indians and Malays having 5 year survival rates of 48.2% (CI 0.444-0.520), 47.2% (CI 0.432-0.512) and 39.7% (CI 0.373-0.421), respectively (p<0.05). The survival rate was lower as the stages increased, with the late stages were mostly seen among the Malays (46%), followed by Chinese (36%) and Indians (34%). Size of tumor>3.0cm; lymph node involvement, ERPR, and HER 2 status, delayed presentation and involvement of both breasts were among other factors that were associated with poor survival. Conclusions: The overall survival rate of Malaysian women with breast cancer was lower than the western figures with Malays having the lowest because they presented at late stage, after a long duration of symptoms, had larger tumor size, and had more lymph nodes affected. There is an urgent need to conduct studies on why there is delay in diagnosis and treatment of breast cancer women in Malaysia.

Relationship between the Development Levels of Learning Organization and Organization Effectiveness in Hospital (의료조직에서 학습조직 구축수준 평가 및 조직유효성과의 관계분석)

  • Lee, Sun Hee;Cho, Woo Hyun;Nam, Jong Hae
    • Health Policy and Management
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    • v.15 no.3
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    • pp.1-16
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    • 2005
  • This study was planned to investigate the relationship between development levels of learning organization and organization effectiveness in Hospital. Data were collected from 285 respondents who have participated in 'Learning Organization Project'(response rate =$50.5\%$). Structured questionnaire were applied by self administrated survey for two weeks since 2003 May. Main results were as follows; In the result of factor analysis, four factor were created and almost questionnaire items were classified into as same categories as theoretical concepts. Cronbach's a coefficient also showed over 0.7 in all categories. This result means that measurement tool to evaluate the development level of learning organization is valid and reliable. In the comparison of the development level of learning organization by participants' specialties, managerial workers perceived the lowest construction level, while medical technicians evaluated it as the highest level. In regression analysis, the perception levels of work environment, task and human aspect showed positive relationship with job competency significantly. For job satisfaction, levels of task and human aspects had positive relationship significantly. In addition, for organizational commitement, levels of organization and human aspect were positive predictors. Finally, for the satisfaction about experience of learning organization project, levels of environment, task and hmm aspects were related positively. We concluded from these result that the positive relationship between construction levels of learning organization and organization effectiveness was extended to hospital, besides industrial fields. We recommend the introduction and facilitation of learning organization project in various settings to improve the competency of knowledge management in individual and organizational levels.