• Radiation Oncology Journal
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• 제27권3호
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• pp.169-172
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• 2009

안구의 전이암은 안구의 악성 종양 중에서 가장 흔한 암이다. 많게는 암으로 인해 사망한 환자의 약 12%에서 안구의 전이가 보고되며, 암 환자의 생존 기간이 늘어남에 따라 안구로의 전이 가능성 또한 증가할 것으로 추정된다. 안구 전이는 실명과 같은 심각한 임상적 증상을 야기할 수 있으며, 조기 발견과 치료를 통해 시력을 보존하고 삶의 질을 최대화 할 수 있으나, 암 환자에 있어 안구 전이의 중요성은 비교적 낮게 평가되고 있다. 안구 전이에 대한 방사선치료는 국소치료이므로 전신적인 부작용이 없으며, 치료에 대한 반응이 조기에 나타나므로 실명 위기에 있는 안구 전이 환자에게 효과적인 치료법이 될 수 있다.

• Tuberculosis and Respiratory Diseases
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• 제59권1호
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• pp.93-96
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• 2005

저자들은 좌안의 시력 저하를 주소로 내원한 52세의 남자 환자에서 안구를 비롯한 간과 뇌 등에 전이성 병변을 동반한 세기관지폐포암 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

• Journal of Chest Surgery
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• 제43권1호
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• pp.117-119
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• 2010

맥락막 흑색종은 성인에서 가장 빈번한 안구 내 종양이다. 간, 폐, 뼈로 전이를 잘하며 그 예후는 나쁜 것으로 알려져 있다. 본 논문에서 저자들은 늑골 및 기관지에 전이된 맥락막 흑색종에 대하여 수술적 절제를 하였으며 이를 보고하고자 한다.

• 한국임상수의학회지
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• 제40권4호
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• pp.283-287
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• 2023

A 10-year-old spayed female beagle dog presented with a 2-month history of third-eyelid elevation in the left eye (OS). Ophthalmic examination revealed slightly diminished corneal and palpebral reflexes along with exophthalmos in the OS. Schirmer's tear test and intraocular pressure values were within the normal range for the OS. Slit-lamp biomicroscopy revealed protrusion of the third eyelid and corneal opacity in the OS. Fundoscopy revealed a prominent black mass in the OS covering the optic nerve. Tapetal hyper-reflectivity was also observed around the mass. Ocular ultrasonography showed a 0.74 × 0.67 cm echogenic posterior segment mass around the optic nerve protruding into the retrobulbar space. Computed tomography revealed a contrast-enhanced soft tissue lesion in the posteromedial aspect of the left eyeball protruding into the retrobulbar region, and the optic nerve was suspected to be involved. No evidence of osteolytic changes in the adjacent bone or distant metastasis was observed. Enucleation was performed to prevent potential metastasis or local invasion of the mass and to relieve discomfort due to exposure to keratopathy resulting from lagophthalmos. Histopathological examination revealed a central choroidal melanocytoma extending into the optic nerve. No local recurrence was detected until 16 months postoperatively.

• Tuberculosis and Respiratory Diseases
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• 제50권5호
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• pp.624-629
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• 2001

우안 시력 장애와 안구종괴를 주소로 내원한 환자에서 폐종괴가 관찰되어 경기관지 폐생검과 안구 적출술을 시행하여 폐선암의 우안구 전이를 진단한 1예를 경험하여 보고하는 바이다.

• 한국임상수의학회지
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• 제35권6호
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• pp.315-318
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• 2018

A 13-year-old spayed female Beagle dog was referred with high intraocular pressure, hyperemia, and exophthalmos of the left eye and underwent ultrasound, which revealed a mass in the ciliary body of the left eye. Magnetic resonance (MR) imaging was ordered to evaluate invasion of surrounding structures and metastasis to the brain via the optic nerve. On MR imaging, a single, well-defined, smoothly marginated, triangular-to-oval-shaped mass was found. The mass was hyperintense on T1-weighted images and hypointense on T2-weighted images, similar to a previous case of ocular melanoma. The mass originated from the ciliary body and extended from the anterior chamber to the posterior chamber. Slight enhancement was observed in the mass. There was no evidence of invasion into surrounding structures or the optic nerve, and no sign of metastasis to the brain. The mass was histopathologically diagnosed as benign uveal melanocytoma.

• 한국임상수의학회지
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• 제32권2호
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• pp.205-208
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• 2015

6년령 중성화 수컷의 말티즈가 서울대학교 부속 동물병원에 내원하였다. 안검사 상 우안의 전방출혈 및 안방수 흐림이 확인되었으며 포도막염에 대한 치료가 진행되었다. 4개월 후 우안 홍채의 등쪽 측면의 전방변위가 확인되었으며 안초음파 검사상 모양체 유래의 종괴로 잠정 진단되었다. 흉부 및 복부 영상검사에서는 종양의 전이소견이 발견되지 않았다. 이후 지속적인 포도막염과 종괴의 종대로 인해 우안의 안구 적출을 실시하였다. 조직병리학적 검사에서 우안의 종괴는 만성적인 출혈을 동반한 전포도막 흑색세포종으로 확진되었다. 본 증례와 같이 안내 종양 환자에서 비수술적인 처치로 눈의 지속적인 출혈이나 염증이 호전되지 않는 경우, 안구적출을 통한 적절한 안내 종양의 제거가 고려되어야 한다.

• 한국임상수의학회지
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• 제35권5호
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• pp.233-236
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• 2018

A 13-year-old spayed female Beagle dog was referred with high intraocular pressure, hyperemia, and exophthalmos of the left eye and underwent ultrasound, which revealed a mass in the ciliary body of the left eye. Magnetic resonance (MR) imaging was ordered to evaluate invasion of surrounding structures and metastasis to the brain via the optic nerve. On MR imaging, a single, well-defined, smoothly marginated, triangular-to-oval-shaped mass was found. The mass was hyperintense on T1-weighted images and hypointense on T2-weighted images, similar to a previous case of ocular melanoma. The mass originated from the ciliary body and extended from the anterior chamber to the posterior chamber. Slight enhancement was observed in the mass. There was no evidence of invasion into surrounding structures or the optic nerve, and no sign of metastasis to the brain. The mass was histopathologically diagnosed as benign uveal melanocytoma.

• Journal of Korean Neurosurgical Society
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• 제61권1호
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• pp.60-65
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• 2018

Objective : Choroidal metastases (CMs) are the most common intraocular tumor. Management is mainly radiation therapy with goals of pain control and visual improvement. However, many radiation-related complications are reported. Since gamma knife radiosurgery (GKS) for CM was first reported in 1995, few cases have been reported. We report 7 cases of CMs treated with GKS. Methods : From April 2011 to November 2014, 7 patients with CM underwent GKS. Their median age at treatment was 64 years (range, 51-71 years). Four males and three females were treated. Lung cancer was the most common primary pathology, followed by renal cell carcinoma and stomach cancer. Four patients had multiple cerebral lesions and were treated simultaneously for choroidal lesions. The median marginal dose of 20 Gy (range, 15-25 Gy) was administered at the 50% isodose line. Results : Median follow-up period after GKS was 8 months (range, 2-38.3 months). Four patients expired due to underlying malignancy progression. Except for two patients who were not followed with magnetic resonance image after GKS, all patients showed size reduction in the treated lesions, but a new choroidal lesion appeared in one patient and one recurred. Six of seven patients reported subjectively improved visual symptoms. Visual acuity improved in 2 patients, and 2 were stable upon objective examination. One patient showed no improvement in visual acuity, but ocular pain was relieved; another patient showed improved vision and tumor remission, but visual deterioration recurred. Conclusion : GKS was shown to be safe and effective and should be considered for CM treatment.