• Journal of Korean Neurosurgical Society
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• 제30권sup2호
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• pp.344-347
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• 2001

Intramedullary spinal tuberculoma is a rare form of central nervous system tuberculosis. The authors presented a case of 41 years old male with intramedullary and intradural extramedullary tuberculoma of the thoracic spinal cord without systemic involvement. The preoperative diagnosis was a metastatic cancer. Subtotal removal of intradural extramedullary and intramedullary mass was performed and pathological diagnosis was tuberculosis granuloma. We suggest that Intramedullary spinal tuberculoma must be considered in the differential diagnosis of the spinal cord compressive lesions in our country.

• Journal of Korean Neurosurgical Society
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• 제54권1호
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• pp.61-64
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• 2013

As a cause of spinal cord compression, intramedullary spinal tuberculoma with central nervous system (CNS) involvement is rare. Aurthors report a 66-year-old female presented with multiple CNS tuberculomas including spinal intramedullary tuberculoma manifesting paraparesis and urinary dysfunction. We review the clinical menifestation and experiences of previous reported literature.

• Tuberculosis and Respiratory Diseases
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• 제49권2호
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• pp.237-245
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• 2000

폐결핵을 치료하는 중 갑작스럽게 생긴 하지의 근력저하와 배뇨장애를 호소하는 환자에서, MRI를 이용하여 척수내 결핵종이 진단되었다. 항결핵 제재와 대량의 스테로이드를 5일간 사용한 후 신경학적 증상은 호전되어 결핵치료를 지속하던 중 20일째 전신경련이 발생하여 다발성 뇌결핵종이 동반되어 있음이 MRI상에 나타났다. 이후 내과적 치료만으로 방사선 소견과 임상증상이 호전되어 가고 있어 9개월째 있는 증례이다. 우리나라는 결핵의 유병률이 높고 다제약제내성결핵이 늘고 있어, 신경학적 증상을 호소하는 환자에서는 반드시 중추신경계 결핵을 염두에 두고 MRI를 시행하면 중추신경계 결핵종의 발견율이 높아질 것으로 사료되어 이에 보고하는 바이다.

• Journal of Korean Neurosurgical Society
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• 제41권6호
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• pp.408-410
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• 2007

"Paradoxical deterioration" during antituberculous therapy is generally defined as the clinical or radiological worsening of pre-existing tuberculous lesions or the development of new lesions in a patient who initially improves. The phenomenon of paradoxical deterioration in intramedullary tuberculoma of the spinal cord is rare and is a less established entity. The authors present an unusual case of paraparesis as a result of paradoxical deterioration of intramedullary tuberculoma despite adequate antituberculous therapy. Here, we review the relevant literatures and discuss its possible pathogenic mechanisms.

• Journal of Korean Neurosurgical Society
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• 제44권1호
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• pp.36-39
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• 2008

Although tuberculosis of the central nervous system is well known, the incidence of intramedullary tuberculomas is low and a combination of intramedullary with intracranial tuberculomas is extremely rare. We report a case of disseminated tuberculoma involving brain and spine with miliary pulmonary tuberculosis in a 66-year-old woman initially presenting with fever, general weakness, back pain and motor weakness of both lower extremities. Despite medical therapy, she developed progressive motor weakness of both lower extremities with muscle strength 1/5 in both lower extremities. Urgent surgical intervention was followed and her muscle power and motor functions were improved gradually. The anti-tuberculous drugs were continued and the follow-up magnetic resonance imaging (MRI) of brain and spine showed that the lesions had become smaller or disappeared.