• The Journal of Korean Medicine
• /
• v.26 no.4
• /
• pp.56-61
• /
• 2005

Objectives: The purpose of this study was to evaluate the effects of Baekyeum (BKE) on intestinal motility. Methods: The effects of BKE on intestinal motility at the physiological state were evaluated by determination of intestinal motility after administration of a charcoal meal. The effects of BKE on intestinal motility at cabachol-induced activated state and loperamide induced suppressed state were also evaluated by determination of intestinal motility after administration of charcoal meal. Results: BKE didn't affect the intestinal motility in physiological state, and BKE didn't affect the intestinal motility at the carbachol-induced activated state. BKE activated significantly the intestinal motility at the loperamide-induced suppressed state. Conclusions: It can be concluded that BKE is an effective herbal prescription for cancer-patients with gastrointestinal dysfunction, especially intestinal stasis.

• Journal of Acupuncture Research
• /
• v.25 no.5
• /
• pp.27-42
• /
• 2008

Objectives : The purpose of this study was to observe the effects of acupuncture and electro-acupuncture at $LR_3$ on intestinal motility in rat. Methods : We made over-activated state of intestinal motility with carbachol and suppressed state of intestinal motility with loperamide in rat and carried out needle retention acupuncture and high frequency electro-acupuncture at $LR_3$ in rat devided into pre-treatment group and post-treatment group. The charcoal travel rate was measured to evaluate the intestinal motility. Results : 1. High frequency electro-acupuncture at $LR_3$ have significant influences on intestinal motility of rat in normal state. 2. Pre-treatment of needle retention acupuncture, high frequency electro-acupuncture significantly decreased intestinal motility in rat which over-activated with carbachol. 3. Post-treatment of high frequency electro-acupuncture significantly increased intestinal motility in rat which suppressed with loperamide. Conclusions : These results suggest that acupuncture and electro-acupuncture at $LR_3$ are effective on intestinal motility in rat.

• Journal of Acupuncture Research
• /
• v.26 no.2
• /
• pp.79-89
• /
• 2009

Objectives : The aim of this study was to observe the effect of acupuncture and high frequency electroacupuncture at $ST_{39}$ on intestinal motility in rats. Methods: We made over-activated state of intestinal motility with carbachol and suppressed state of intestinal motility with loperamide in rat and carried out needle retention acupuncture and high frequency electroacupuncture at $ST_{39}$ or sham point in rat divided into pre-treatment group and post-treatment group. We fed charcoal to them after the treatment and measured the travel rate of charcoal in the gastrointestinal tract to observe intestinal motility. Results : Examining intestinal motility of normal rat treated with needle retention acupuncture at $ST_{39}$ significantly suppressed intestinal motility. Pre-treatment of needle retention acupuncture significantly suppressed intestinal motility in rat which over-activated with carbachol. Pre-treatment and post-treatment of high frequency electroacupuncture significantly suppressed intestinal motility in rat which over-activated with carbachol. All of the pre-treatment and post-treatment of needle retention acupuncture, high frequency electroacupuncture showed no significant effect than control group on intestinal motility of rat which was suppressed with loperamide. Conclusions : These results suggest that acupuncture and high frequency electroacupuncture at $ST_{39}$ have preventive and therapeutic effects on over-activated intestinal motility, and high frequency electroacupuncture is more effective.

• Journal of Acupuncture Research
• /
• v.33 no.1
• /
• pp.9-21
• /
• 2016

Objectives : The aim of this study was to investigate the effect of low frequency electro-acupuncture at ST39 on intestinal motility in rats. Methods : Intestinal hypermotility and hypomotility in rats were induced by oral carbachol ingestion and loperamide injection. Rats were divided into seventeen experimental groups including the normal and holder groups. The rats were induced with intestinal hypermotility and hypomotility and divided into pre and post-treatment groups. I also carried out acupuncture (needle retention) and low frequency electro-acupuncture at ST39 or the sham point. I fed charcoal to rats after the treatment and calculated its distance travelled in the gastrointestinal tract, which was compared by groups so as to determine which treatment was more effective in increasing or decreasing intestinal motility. Results : 1. In normal rats, low frequency electro-acupuncture at ST39 showed no significant effect on intestinal motility. 2. Pre-treatment with acupuncture (needle retention) at ST39 on intestinal motility over-activated with carbachol significantly decreased intestinal motility in rats. 3. Pre-treatment with low frequency electro-acupuncture at ST39 on intestinal motility over-activated with carbachol significantly decreased intestinal motility in rats. 4. Pre-treatment with acupuncture (needle retention and low frequency electro-acupuncture) at ST39 showed no significant effect on intestinal hypomotility in rats that was induced by loperamide injection. Conclusions : These results suggest that acupuncture (needle retention) and low frequency electro-acupuncture at ST39 have preventive effects on intestinal hypermotility. Regardless of the stimulation method, ST39 showed an effect on intestinal motility. Further study is required to confirm other effects of ST39.

• Korean Journal of Acupuncture
• /
• v.25 no.2
• /
• pp.179-197
• /
• 2008

Objectives and Methods : The purpose of this study was to observe the effects of acupuncture and electro-acupuncture (EA) at PC6 on intestinal motility in rats. We made over-activated state of intestinal motility with carbachol and suppressed state of intestinal motility with loperamide in rat, and carried out acupuncture with needle retained (NR), low frequency (2 Hz) EA and high frequency (100 Hz) EA at PC6 before or after the administration of carbachol or loperamide. The charcoal travel rate was measured to evaluate the intestinal motility. Results : 1. NR showed no significant influences on intestinal motility of rat in normal state. While, 2 Hz EA and 100 Hz EA at PC6 significantly increased the intestinal motility of rat in normal state. 2. All of the pre-treatment and post-treatment of NR, 2 Hz EA and 100 Hz EA at PC6 showed no significant effects on intestinal motility of rat which was over-activated with carbachol. 3. Both pre-treatment and post-treatment of NR significantly increased intestinal motility in rat which was suppressed with loperamide. 4. Pre-treatment of 2 Hz EA and post-treatment of 100 Hz EA significantly increased intestinal motility in rat which was suppressed with loperamide. Conclusions : These results suggest that acupuncture (NR) and EA on PC6 have preventive and therapeutic effect on suppressed intestinal motility, and NR may be more effective than EA in that condition.

• The Korea Journal of Herbology
• /
• v.25 no.4
• /
• pp.113-120
• /
• 2010

Objectives : This study was conducted to compare Chaenomelis Sinensis Fructus with Chaenomelis Lagenariae Fructus, and to examine Fructus chaenomelis having an influence on Intestinal Motility. Methods : We compared Chaenomelis Sinensis Fructus with Chaenomelis Lagenariae Fructus, by observing their effects on Intestinal Motility. Oral administration of water extracts of Chaenomelis Sinensis Fructus and Chaenomelis Lagenariae Fructus into albino rats was followed by dealing with carbachol or loperamide, injecting charcoal meal and measuring the moving length in the intestine. Results : By Chaenomelis Sinensis Fructus and Chaenomelis Lagenariae Fructus, the Intestinal Motility of normal albino rats did not change significantly. Chaenomelis Sinensis Fructus and Chaenomelis Lagenariae Fructus controled the accelerated Intestinal Motility of albino rats. Chaenomelis Sinensis Fructus was not different from the extracting method, Chaenomelis Lagenariae Fructus had effects of control on extracting by methanol significantly. When Chaenomelis Sinensis Fructus was compared with Chaenomelis Lagenariae Fructus, the former was proved to have control effects on Intestinal Motility in decoction extracts and extracts by ethyl ether higher than the latter. By both Chaenomelis Sinensis Fructus and Chaenomelis Lagenariae Fructus, the declined Intestinal Motility was not changed significantly. Conclusion : Chaenomelis Fructus suppressed the exasperated Intestinal Motility by carbachol, but did not influence the dropped Intestinal Motility by loperamide. In addition, Chaenomelis Sinensis Fructus was more excellent than Chaenomelis Lagenariae Fructus in its control effects of Intestinal Motility. inhibitory effects by DKT represent a potential therapeutic approach to the treatment of inflammatory diseases.

• Journal of Veterinary Clinics
• /
• v.19 no.2
• /
• pp.204-206
• /
• 2002

The effects of electroacupuncture on small intestinal motility in dogs were investigated. The acupoints used in the experiment were Shao Ze (SI-1), Hou Xi. (SI-3), Yang Lao (SI-6), Zhi Zheng (SI-7) and Xiao Hai (SI-8) which belong to small intestine meridian, Xiao Chang Shu (BL-27) which belongs to urinary bladder meridian, and Guan Yuan (CV-4) which belongs to conception vessel meridian. The anupoints were stimulated with 2-4 volt and 5 Hz for 20 minutes Electroacupuncture at Shao Ze, Yang Lao, and Xiao Hai acupoints increased the intestinal motility, but at Guan Yuan decreased the motility. The acupuncture at Hou Xi, Zhi Zheng and Xiao Chang Shu acupoints showed an increase or decrease of the intestinal movement. The results indicate that the electroacupuncture at Guan Yuan acupoint may depress intestinal motility in cases such as vomiting or diarrhea, and the acupuncture at Shao Ze, Yang Lao, and Xiao Hai acupoints to promote the motility in cases of digestive disturbance may be effective in veterinary practice.

• Journal of Acupuncture Research
• /
• v.25 no.4
• /
• pp.59-69
• /
• 2008

Objectives : The purpose of this study was to observe the effects of acupuncture and electro-acupuncture(EA) at $LI_{11}$ on intestinal motility in rats. Methods : We made over-activated and suppressed state of intestinal motility with carbachol and loperamide in rat and carried out acupuncture with needle retained(NR), low frequency(2 Hz) EA and high frequency(100Hz) EA at $LI_{11}$ before or after the administration of carbachol or loperamide. The charcoal travel rate was measured to evaluate the intestinal motility. Results : 1. NR, 2Hz EA and 100Hz EA at $LI_{11}$ showed no significant influences on intestinal motility of rat in normal state. 2. All of the pre-treatment and post-treatment of NR, 2Hz EA and 100Hz EA at $LI_{11}$ showed no significant effects than control group on intestinal motility of rat which was over-activated with carbachol. 3. The pre-treatment of 2Hz EA and 100Hz EA at $LI_{11}$ on intestinal motility of rat which was suppressed with loperamide showed no significant influences but in the L-$LI_{11}$-EA(L) and L-$LI_{11}$-EA(H) groups, intestinal motility was significantly increased than L-control group. Conclusions : These results suggest that acupuncture and EA on $LI_{11}$ have preventive effect and therapeutic effect on suppressed intestinal motility, and EA is more effective than NR.

• Journal of Acupuncture Research
• /
• v.25 no.4
• /
• pp.11-29
• /
• 2008

Objectives : The purpose of this study was to observe the effects of acupuncture and electro-acupuncture at $LI_4$ on intestinal motility in rat. Methods : We made over-activated state of intestinal motility with carbachol and suppressed state of intestinal motility with loperamide in rat and carried out needle retention acupuncture, low frequency electro-acupuncture and high frequency electro-acupuncture at $LI_4$ or sham point in rat devided into pre-treatment group and post-treatment group. and we resulted as follow for measuring charcoal travel rate to observe intestinal motility. Results : 1. Any of needle retention acupuncture, low frequency electro-acupuncture and high frequency electro-acupuncture at $LI_4$ have no significant influences on intestinal motility of rat in normal state. 2. All of the pre-treatment and post-treatment of needle retention acupuncture, low frequency electro-acupuncture and high frequency electro-acupuncture didn't significantly decrease intestinal motility in rat which over-activated with carbachol. 3. Pre-treatment of needle retention acupuncture and high frequency electro-acupuncture significantly increased intestinal motility in rat which suppressed with loperamide. 4. Post-treatment of needle retention acupuncture, low frequency electro-acupuncture and high frequency electro-acupuncture significantly increased intestinal motility in rat which suppressed with loperamide. Conclusions : These results suggest that acupuncture on $LI_4$ have preventive effect and therapeutic effect on suppressed intestinal motility, and especially high frequency electro-acupuncture is more effective.

• The Journal of Korean Medicine
• /
• v.33 no.3
• /
• pp.20-32
• /
• 2012

Objectives: The purpose of this study was to investigate the effect of acupuncture and electro-acupuncture (EA) of low and high frequencies at Haegye (ST41) in rats. Methods: The intestinal motility of rats was experimentally suppressed with loperamide. Acupuncture, low frequency EA and high frequency EA were carried out before the loperamide administration in the pre-treatment group, and after the loperamide administration in the post-treatment group. The rats were fed charcoal and the travel rate of charcoal in the gastrointestinal track was measured to analyze the effect of acupuncture, low frequency EA and high frequency EA on the intestinal hypo-motility. Results: 1. None of acupuncture, low frequency EA or high frequency EA at ST41 showed significant influences on intestinal motility of rats in normal status. 2. Pre-treatment with acupuncture at ST41 showed no significant effect on the intestinal hypo-motility induced by loperamide in rats. 3. Pre-treatment with low frequency EA and high frequency EA at ST41 significantly reduced the suppression of intestinal motility by loperamide in rats. 4. Post-treatment of acupuncture, low frequency EA and high frequency EA at ST41 had no significant influences on the intestinal hypo-motility induced by loperamide in rats. Conclusions: These results suggest that low and high frequency EA at ST41 may be effective to prevent gastric disorders such as intestinal hypo-motility.