• Nutritional Sciences
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• 제7권4호
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• pp.214-217
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• 2004

Dietary intervention and simvastatin is beneficial in the prevention cardiovascular diseases by lowering plasma lipid levels. Endothelial dysfunction is associated with coronary artery disease and its risk factors and is reversed by dietary intervention. It has been suggested that hyperlipidemia contributes to the development of atherosclerosis by increasing inducible nitric oxide synthase (iNOS) expression via intimal thickening. Statins treatment has been found to decrease iNOS expression and atherogenensis in animal models. We hypothesized that dietary intervention and simvastatin therapy could decrease plasma nitric oxide in hypercholesterolemic patients, which would suggest the opportunity for modulation of iNOS expression through the use of statins in a clinical situation. We measured the plasma levels of nitrite and nitrate (NOx) in 19 hyperlipidemia patients. The subjects were under dietary intervention following simvastatin therapy for 12 weeks. As a result, the plasma level of NOx, stable metabolites of nitric oxide (NO), saw a two-fold elevation in hyperlipidemic patients as compared to normal levels. Although 12 weeks of dietary intervention did not lower NOx levels, subsequent 12-week simvastatin (10 mg/day) treatment, along with dietary intervention, lowered NOx levels significantly. This NOx reduction, induced by simvastatin therapy, positively correlated with lowered coronary risk factors (r=0.40, p=0.02). It indicated that simvastatin therapy decreases plasma NOx levels by, perhaps, decreasing iNOS expression or activity leading to the attenuation of the development of neointima.

• 대한감각통합치료학회지
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• 제7권2호
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• pp.37-47
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• 2009

목적: 본연구는 그룹 감각통합치료를 통해 학령기 감각통합장애 아동의 실행, 사회성에 미치는 효과에 대하여 알아보았다. 연구방법: 연구대상은 만 7~13세의 학령기 아동 5명으로, 실2험기간은 009년 6월에서 11월까지였다. 그룹 감각통합치료는 주 1회, 회7기 당 0분씩 총 26회기의 그룹 감각통합치료를 실시하였다. 아동의 실행능력을 알아보기 위해 Bruininks-Oseretasky Test of Motor Proficiency(BOT-2), 사회성을 알아보기 위해 사회성 기초기능척도를 사용하였다. 그룹 감각통합치료의 효과를 알아보기 위해 단일집단 사전-사후 설계(one group pretest-posttest design)을 사용하였다. 그룹 감각통합치료 사전/사후의 BOT-2,(Wi사회성 기초기능척도의 차이는 윌콕슨 순위검정 lcoxon matched-pairs signed ranks test)을 사용하여 분석하였다. 결과: 그룹 감각통합치료는 학령기 아동의 실행능력, 사회성 향상에 효과가 있었다. 결론: 본 연구는 감각통합장애가 있는 학령기 아동에게 그룹 감각통합치료에 대한 효과를 제시하여 학령기 아동의 그룹치료에 대한 초기연구모델을 제시하였으며, 감각통합 치료적용이 보다 확대될 수 있는 기회를 제공하였다. 향후 연구에서 연구 대상자의 수를 늘리고 표준 데이터를 제시해 줄 수 있는 다양한 평가기준을 사용한다면 보다 객관적이고 긍정적인 결과가 나올 것으로 사료된다.

• 대한물리치료과학회지
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• 제16권3호
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• pp.67-74
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• 2009

Background: Various functional factors should be incorporated during assessment and intervention for patient rehabilitation. Stable respiratory function is one of required factors for functional restoration. To maximize respiratory physical therapy intervention outcome, it is required to understand clinical features of respiratory diseases and physical therapy approaches. Methods: Previous studies were systematically reviewed through computerized search. Methodological qualities of selected studies were evaluated and the levels of recommendations were determined. Results: Assessment for respiratory pattern and thoracic mobility is of importance to improve cardiopulmonary fitness during physical reconditioning. Application of optimal therapeutic protocol can increase thoracic mobility and respiratory function. Interdisciplinary communication is critical during rehabilitation for respiratory patients. Health care provider should have professional knowledge and experience for cardiopulmonary fitness and obligation to endeavor for patients' respiratory rehabilitation. It is necessary to standardize therapeutic intervention, and rehabilitative respiratory exercise should be applied to confirm the effects of intervention. Conclusion: Respiratory diseases that may reduce patients' quality of life and cardiopulmonary fitness should be resolved through physical therapy approaches. Through conducting research, effect of evidence-based and patients' function-oriented intervention can be determined.

• 아동학회지
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• 제35권1호
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• pp.77-93
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• 2014

The purpose of this research is to develop and evaluate an emotional intervention program for maladaptive preschoolers. The emotional intervention program focused on nurturing the ability to express emotions in healthy ways and how to empathize with others while the preschoolers perceives negative emotions. The participants in this study were nineteen preschoolers, residing in S city. Nineteen subjects were assigned to an experimental group practicing an emotional intervention program. The preschoolers participated in 8-session programs once a week over the course of eight weeks. Descriptive statistics, paired t-test and hierarchical cluster analysis were performed. The results of this study were as follows. First, there were significant differences between posttests and pretests results. The results showed a decrease in maladaptive preschooler's problematic behaviors and aggressive strategies. The maladaptive preschoolers showed more representations of anxiety, avoidance/withdrawal, and deregulated/aggression. In addition the results also showed a decrease in preschooler's representations of anxiety, avoidance/withdrawal, and deregulated/aggression.

• 대한감각통합치료학회지
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• 제10권1호
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• pp.21-31
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• 2012

목적 : 본 연구는 형제그룹 감각통합치료가 전반적 발달장애 아동의 사회적 상호작용에 미치는 효과에 대해서 알아보고자 한다. 연구방법 : 전반적 발달장애 진단을 받은 만 7~8세 아동 2명을 대상으로 2011년 7월부터 9월까지 총 8주간 형제그룹 감각통합치료를 실시하였다. 개별실험연구방법(single subject research design) 중 A-B-A' 설계를 사용하였으며, 기초선 A 3회기, 중재기 B 16회기, 기초선 A' 3회기로 총 22회기를 적용하였다. 사회적 상호작용의 질은 기초선 A와 A'기간에 ESI(Evaluation Social Interaction)를 통하여 측정하였다. 사회적 상호작용의 빈도는 기초선 기간에는 중재가 없는 상태에서 측정하였으며, 중재기간에는 매 중재 후 10분간의 자유놀이를 비디오로 촬영하여 등간기록법(interval recording)을 통해 측정하였다. 결과 : 대상 아동 모두에게서 중재 후 사회적 상호작용의 질은 통계적으로 유의한 향상을 보였다. 또한 매 회기 중재 후 실시한 자유놀이에서 대상 아동 모두 기초선 A의 평균과 2표준편차 밴드 이상인 값들이 두 개 이상 연속으로 나타나 사회적 상호작용의 빈도에서도 통계적으로 유의한 변화가 나타났다. 결론 : 형제그룹 감각통합치료가 전반적 발달장애 아동의 사회적 상호작용에 긍정적인 효과가 있음을 확인하였다. 따라서 임상에서 전반적 발달장애 아동에게 사회적 상호작용 향상을 위한 치료방법으로써 형제그룹 감각통합치료를 효과적으로 적용할 수 있을 것이다.

• 한국간호교육학회지
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• 제17권3호
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• pp.464-477
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• 2011

Purposes: The purpose of this study was to identify recent trends of experimental research by analyzing doctoral dissertations in all colleges of nursing in Korea. Methods: The areas of research, the content, methodological and intervention characteristics used in this study were explored in experimental research on doctoral dissertations (n=132) published from 2006 to 2010. Results: In the issues of research, practice/clinical issues were most frequently used. As to outcome measurement, physiological variables increased more than psychological/emotional variables. Most theory applied in the research was taken from other disciplines, and nursing theory was only Roy's adaptation theory. A large majority of the research was quasi-experimental designs and the number of true-experimental designs was very low. In more than half of the dissertations, internal validity was not described, and the described external validity rate was very low. There were more single intervention programs than bundle ones and education/exercise programs were most frequently used as the source of intervention. Conclusion: Doctoral dissertations need to increase and encourage more high quality experimental research to expand nursing knowledge and to develop evidence based nursing practice.

• Journal of Korean Biological Nursing Science
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• 제19권3호
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• pp.141-150
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• 2017

Purpose: The purpose of this study was to investigate the effects of the Korean Dietary Approaches to Stop Hypertension (DASH) education program on oxidative stress, antioxidant capacity, and serum homocysteine (Hcy) level in elderly Korean women. Methods: This was a quasi-experimental study employing non-equivalent control group pretest-posttest design. The DASH group (n= 27) underwent the DASH education program for 12 weeks, whereas the control group (n= 21) was provided one education session. The survey was conducted before and after the intervention period. Results: In DASH group, monounsaturated fatty acid (MUFA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA) intakes significantly increased after the intervention as compared to prior to the intervention. No significant differences were found in the control group. After the intervention, thiobarbituric acid reactive substance (TBARS) and Hcy levels significantly decreased in the DASH group but not in the control group. Conclusion: The DASH education program was effective in reducing oxidative stress and Hcy levels in elderly Korean women.

• Asian Pacific Journal of Cancer Prevention
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• 제17권6호
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• pp.2871-2876
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• 2016

The Pap smear test is recommended for early diagnosis of cervical cancer. The aim of this study was to assess knowledge and behavior regarding the Pap smear test based on the Health Belief Model (HBM) in women referred to premarital counseling classes, Hamadan, Iran. This quasi-experimental study was conducted on 330 women, who were allocated randomly to two case and control groups (n=165). Two educational session classes were performed in the case group. Two stages in before and after intervention groups were evaluated. Analysis of data was performed by SPSS/16.0, using t-test, $x^2$, and McNemar's test. P-values <0.05 were regarded as significant. There was no significant difference between the mean scores of the various structures of this model in two groups before the intervention. However, after the intervention there were significant increase in mean score of knowledge and all variables of HBM in the intervention group(P<0.001). The findings of this study highlight the important role of education about cervical cancer on changing women's beliefs about cervical screening.

• Child Health Nursing Research
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• 제25권3호
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• pp.273-289
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• 2019

Purpose: The purpose of this study was to review the literature on intervention studies for abused children and adolescent in residential facilities in South Korea (ACARF-K). The goal was to understand the problems they experience, to evaluate the content and effectiveness of interventions applied to them, and to develop evidence-based nursing intervention programs. Methods: We used four electronic databases to search for relevant articles. 18 studies according to Whittemore and Knafl's integrative review method to synthesize the literature. Results: The ACARF-K experienced problems in biophysical, psychological, and sociocultural domains related to attachment impairment. Effective intervention strategies were building trust through empathy and fulfillment of needs, encouraging ACARF-K to express themselves and helping them to clarify emotions in an unthreatening environment, and improving their self-concept through activities in which they experienced achievement. Conclusion: Interventions are needed to help restore attachment damage among ACARF-K. The interventions in this study utilized emotional, cognitive, relational, and behavioral therapeutic tools to improve their psychological and social capacities. Future intervention programs for ACARF-K should include these key elements.

• 근관절건강학회지
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• 제29권2호
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• pp.113-123
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• 2022

Purpose: The present study aims to identify research trends on diabetes mellitus (DM) self-management intervention, suggesting directions for follow-up studies through a scoping review. Methods: This study conducted the scoping review process outlined by Arskey and O' Malley using the JBI (Joanna Briggs Institute) template. The databases used were Riss, Kiss, NDSL, KMbase, Google Scholar. This study searched the literature published between January 2011 and November 2021 by entering keywords related to DM self-management. Results: Thirty-five studies were selected for analysis. The period for 24 articles was 12 weeks or longer. The interventions consisted of education, exercise, counseling, and coaching. Not all studies applied the theory of behavior change. Fourteen studies included three factors relating to behavioral, cognitive, emotional, and blood sugar changes to measure effectiveness, while ten studies included all four factors. Most interventions were effective both in DM self-management and self-care. Further, the intervention persistence effect of each study varied. Conclusion: While research on DM self-management intervention has been conducted at domestically and abroad, this decreased during COVID-19 pandemic. This study suggests the importance of systematically developing effective necessary optimal DM self-management interventions that can change behaviors to prevent diabetic complications and improve quality of life.