• 제목/요약/키워드: Interval Mapping

검색결과 140건 처리시간 0.029초

PC기반 8채널 해양 탄성파탐사 시스템을 이용한 고해상 천해저 탐사 (High-resolution Shallow Marine Seismic Survey using a PC based 8-channel Seismic System)

  • 김현도;김진후
    • 한국지구물리탐사학회:학술대회논문집
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    • 한국지구물리탐사학회 2005년도 공동학술대회 논문집
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    • pp.187-194
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    • 2005
  • PC기반의 8채널 해양 탄성파탐사 시스템을 개발하여 천해저 기반암 매핑에 적용시켜 보았다. 본 시스템은 PC에 탑재된 아날로그 신호처리기와 디지털 변환기, 그리고 그룹간격 5 m의 스트리머로 구성되어 있다. 이 시스템은 시스템을 제어하는 자료취득 프로그램과, 자료처리 소프트웨어에 의해 구동된다. PC기반 천해저 해양 탄성파탐사 시스템으로 적절한 자료처리 과정을 거쳐 신호 대 잡음비가 향상된 고해상 2차원 지층 단면도를 작성할 수 있었다.

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Predicting Factors for Positive Vaginal Surgical Margin Following Radical Hysterectomy for Stage IB1 Carcinoma of the Cervix

  • Sethasathien, Sethawat;Charoenkwan, Kittipat;Settakorn, Jongkolnee;Srisomboon, Jatupol
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권5호
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    • pp.2211-2215
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    • 2014
  • Background: To examine the incidence of positive vaginal surgical margins and determine the predicting factors following radical hysterectomy for stage IB1 carcinoma of the cervix. Materials and Methods: The clinical and histological data of 656 FIGO stage IB1 cervical cancer patients who had radical hysterectomy with bilateral pelvic lymphadenectomy (RHPL) from January 2003 to December 2012 were retrospectively reviewed and were analyzed for their association with a positive vaginal surgical margin. A p-value of < 0.05 was considered significant. Results: Thirty-five patients (5.3%) had positive vaginal surgical margins following RHPL; 24 (3.7%) for intraepithelial lesions and 11 (1.7%) for carcinoma. On multivariate analysis, microscopic vaginal involvement by high-grade squamous intraepithelial lesion and/or carcinoma (adjusted odd ratio (OR) 186.8; 95% confidence interval (CI) 48.5-718.5) and squamous histology (OR 8.7; 95% CI 1.7-44.0), were significantly associated with positive vaginal surgical margin. Conclusions: Microscopic vaginal involvement by HSIL and/or carcinoma are strong predictors for positive vaginal surgical margins for stage IB1 cervical cancer patients undergoing radical hysterectomy. Preoperative 'mapping' colposcopy or other strategies should be considered to ensure optimal vaginal resection.

The Role of Enzyme Replacement Therapy in Fabry Disease in Cardiology Perspective

  • Hongo, Kenichi
    • Journal of mucopolysaccharidosis and rare diseases
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    • 제4권1호
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    • pp.21-25
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    • 2018
  • Fabry disease is a hereditary lysosomal storage disorder caused by the reduction or absence of lysosomal enzyme alpha-galactosidase A and the accumulation of glycosphingolipids, such as globotriaosylceramide (Gb3), in various organs, including the heart. The prevention of cardiac involvement in Fabry disease can only be achieved by enzyme replacement therapy (ERT), and the method of assessing the efficacy of ERT should be confirmed. Changes in the electrocardiogram, such as the shortening of PQ interval, prolongation of QTc and repolarization abnormalities as well as left ventricular hypertrophy in voltage criteria, can be used to identify Fabry disease patients; however, the usefulness of electrocardiograms for evaluating the efficacy of ERT is limited. The assessment of left ventricular hypertrophy using echocardiography has been established to evaluate the efficacy of ERT during long-term period. A new technique involving speckled tracking method might be useful for detecting early cardiac dysfunction and identifying the effect of ERT for a relatively short period. The estimation of left ventricular hypertrophy using cardiac magnetic resonance (CMR) is also useful for assessing the efficacy of ERT. Identifying late gadolinium enhancement in CMR may affect the effectiveness of ERT, and the new technique of T1 mapping might be useful for monitoring the accumulation of Gb3 during ERT. Histopathology in cardiac biopsy specimens is another potentially useful method for identifying the accumulation of GB3; however, the use of histopathology to evaluate of the efficacy of ERT is limited because of the invasive nature of an endomyocardial biopsy.

Identification of quantitative trait loci for physical and chemical properties of rice grain

  • Cho, Yong-Gu;Kang, Hyeon-Jung;Lee, Young-Tae;Jong, Seung-Keun;Eun, Moo-Young;McCouch, Susan R.
    • Plant Biotechnology Reports
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    • 제4권1호
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    • pp.61-73
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    • 2010
  • Quantitative trait loci (QTL) associated with six physical traits of cooked rice and seven chemical properties of rice grain were identified using a recombinant inbred (RI) population of rice evaluated over 3 years at the National Honam Agricultural Research Institute in Korea. The RI population consisted of 164 lines derived from a cross between Milyang23 and Gihobyeo, and the genetic map consisted of 414 molecular markers. A total of 49 QTL were identified for the 13 physico-chemical properties using composite interval mapping. Of these, 13 QTL were identified for 2 or more years, while 36 were detected in only 1 year. Five QTL were identified over all 3 years and will be useful for marker-assisted improvement of rice grain quality in Korea. The two QTL with the highest LOD scores, adhesiveness1.2 and potassium content7.1, provide a valuable starting point for positional cloning of genes underlying these QTL.

Comparison of Two Methods for Measuring Daily Path Lengths in Arboreal Primates

  • Lappan, Susan
    • Journal of Ecology and Environment
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    • 제30권2호
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    • pp.201-207
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    • 2007
  • Researchers have used a variety of methods to measure patterns of animal movement, including the use of spatial data (mapping the position of a moving animal at specified intervals) and direct estimation of travel path length by pacing under a moving animal or group. I collected movement data from five groups of siamangs (Symphalangus syndactylus) using two different methods concurrently to estimate the effects of the method of data collection on estimates of daily path length (DPL). Estimates of DPL produced from spatial data collected at 15-minute intervals were 12% lower than estimates of DPL produced by pacing under the traveling animal. The actual magnitude of the difference was correlated with the travel distance, but there was no correlation between the proportional difference and the travel distance. While the collection of spatial data is generally preferable, as spatial data permit additional analyses of patterns of movements in two or three dimensions, the relatively small difference between the DPL's produced using different methods suggests that pacing is an acceptable substitute where the collection of spatial data is impractical. I also subsampled the spatial data at increasing time intervals to assess the effect of sampling interval on the calculation of daily path lengths. Longer sampling intervals produced significantly shorter estimates of travel paths than shorter sampling intervals. These results suggest that spatial data should be collected at short time intervals wherever possible, and that sampling intervals should not exceed 30 minutes. Researchers should be cautious when comparing data generated using different methods.

경암지반 NATM 터널에서 암반분류 및 계측에 의한 최적지보공 선정에 관한 연구 (Selection of Optimum Support based on Rock Mass Classification and Monitoring Results at NATM Tunnel in Hard Rock)

  • 김영근;장정범;정한중
    • 터널과지하공간
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    • 제6권3호
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    • pp.197-208
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    • 1996
  • Due to the constraints in pre site-investigation for tunnel, it is essential to redesign the support structures suitable for rock mass conditions such as rock strength, ground water and discontinuity conditions for safe tunnel construction. For the selection of optimum support, it is very important to carry out the rock mass classification and in-situ measurement in tunnelling. In this paper, in a mountain tunnel designed by NATM in hard rock, the selectable system for optimum support has been studied. The tunnel is situated at Chun-an in Kyungbu highspeed railway line with 2 lanes over a length of 4, 020 m and a diameter of 15 m. The tunnel was constructed by drill & blasting method and long bench cut method, designed five types of standard support patterns according to rock mass conditions. In this tunnel, face mapping based on image processing of tunnel face and rock mass classification by RMR carried out for the quantitative evaluation of the characteristics of rock mass and compared with rock mass classes in design. Also, in-situ measurement of convergence and crown settlement conducted about 30 m interval, assessed the stability of tunnel from the analysis of monitoring data. Through the results of rock mass classification and in-situ measurement in several sections, the design of supports were modified for the safe and economic tunnelling.

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Transcriptomic Profiling of Resistant and Susceptible Soybean Genotypes Following Inoculation of Phytophthora sojae

  • Hee Jin You;Jeongsun Lee;Sungwoo Lee
    • 한국작물학회:학술대회논문집
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    • 한국작물학회 2022년도 추계학술대회
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    • pp.188-188
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    • 2022
  • Our previous study identified a resistance locus to Phytophthora sojae (isolate 2457) in an interval of 3.8-4.7 Mbp on chromosome 3 via genetic mapping using a 'Daepung'×'Daewon' recombinant inbred population. Since differential gene expression between Daepung (susceptible) and Daewon (resistant) after inoculation of P. sojae is unknown, RNA sequencing was carried out to compare transcriptomic changes between the two genotypes following inoculation with P. sojae isolate 2457. The two varieties were inoculated using hypocotyl inoculation at the VC stage and stem tissue of 1 cm above and below of the inoculated site were sampled at 0, 6, 12 hours after inoculation (hai), respectively. Differentially expressed genes (DEGs) under same cultivar in different time point and Daepung vs. Daewon in same time point were investigated. In comparison of Daepung vs. Daewon at 12 hai, a total of 3,513 DEGs were identified, including two nucleotide-binding site-leucine rich repeat (NBS-LRR) genes (Glyma.03g034800 and Glyma.03g034900) that are located in the previously reported resistance locus on chromosome 3. In addition, 14,966 DEGs were detected between 0 vs. 6 hai, containing one of candidate genes (Glyma.03g035300). This gene was upregulated by up to 4-fold in Daewon and Daepung. Additional results will be further discussed in the presentation. This study will provide valuable information for soybean crop improvement.

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딥러닝 알고리즘을 이용한 매설 배관 피복 결함의 간접 검사 신호 진단에 관한 연구 (Indirect Inspection Signal Diagnosis of Buried Pipe Coating Flaws Using Deep Learning Algorithm)

  • 조상진;오영진;신수용
    • 한국압력기기공학회 논문집
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    • 제19권2호
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    • pp.93-101
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    • 2023
  • In this study, a deep learning algorithm was used to diagnose electric potential signals obtained through CIPS and DCVG, used indirect inspection methods to confirm the soundness of buried pipes. The deep learning algorithm consisted of CNN(Convolutional Neural Network) model for diagnosing the electric potential signal and Grad CAM(Gradient-weighted Class Activation Mapping) for showing the flaw prediction point. The CNN model for diagnosing electric potential signals classifies input data as normal/abnormal according to the presence or absence of flaw in the buried pipe, and for abnormal data, Grad CAM generates a heat map that visualizes the flaw prediction part of the buried pipe. The CIPS/DCVG signal and piping layout obtained from the 3D finite element model were used as input data for learning the CNN. The trained CNN classified the normal/abnormal data with 93% accuracy, and the Grad-CAM predicted flaws point with an average error of 2m. As a result, it confirmed that the electric potential signal of buried pipe can be diagnosed using a CNN-based deep learning algorithm.

한반도 상공의 오존층 변화 1985~2009 (The Variations of Stratospheric Ozone over the Korean Peninsula 1985~2009)

  • 박상서;김준;조나영;이윤곤;조희구
    • 대기
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    • 제21권4호
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    • pp.349-359
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    • 2011
  • The climatology in stratospheric ozone over the Korean Peninsula, presented in previous studies (e.g., Cho et al., 2003; Kim et al., 2005), is updated by using daily and monthly data from satellite and ground-based data through December 2009. In addition, long-term satellite data [Total Ozone Mapping Spectrometer (TOMS), Ozone Monitoring Instrument (OMI), 1979~2009] have been also analyzed in order to deduce the spatial distributions and temporal variations of the global total ozone. The global average of total ozone (1979~2009) is 298 DU which shows a minimum of about 244 DU in equatorial latitudes and increases poleward in both hemispheres to a maximum of about 391 DU in Okhotsk region. The recent period, from 2006 to 2009, shows reduction in total ozone by 6% relative to the values for the pre-1980s (1979~1982). The long-term trends were estimated by using a multiple linear regression model (e.g., WMO, 1999; Cho et al., 2003) including explanatory variables for the seasonal variation, Quasi-Biennial Oscillation (QBO) and solar cycle over three different time intervals: a whole interval from 1979 to 2009, the former interval from 1979 to 1992, and the later interval from 1993 to 2009 with a turnaround point of deep minimum in 1993 is related to the effect of Mt. Pinatubo eruption. The global trend shows -0.93% $decade^{-1}$ for the whole interval, whereas the former and the later interval trends amount to -2.59% $decade^{-1}$ and +0.95% $decade^{-1}$, respectively. Therefore, the long-term total ozone variations indicate that there are positive trends showing a recovery sign of the ozone layer in both North/South hemispheres since around 1993. Annual mean total ozone (1985~2009) is distributed from 298 DU for Jeju ($33.52^{\circ}N$) to 352 DU for Unggi ($42.32^{\circ}N$) in almost zonally symmetric pattern over the Korean Peninsula, with the latitudinal gradient of 6 DU $degree^{-1}$. It is apparent that seasonal variability of total ozone increases from Jeju toward Unggi. The annual mean total ozone for Seoul shows 323 DU, with the maximum of 359 DU in March and the minimum of 291 DU in October. It is found that the day to day variability in total ozone exhibits annual mean of 5.7% in increase and -5.2% in decrease. The variability as large as 38.4% in increase and 30.3% in decrease has been observed, respectively. The long-term trend analysis (e.g., WMO, 1999) of monthly total ozone data (1985~2009) merged by satellite and ground-based measurements over the Korean Peninsula shows increase of 1.27% $decade^{-1}$ to 0.80% $decade^{-1}$ from Jeju to Unggi, respectively, showing systematic decrease of the trend magnitude with latitude. This study also presents a new analysis of ozone density and trends in the vertical distribution of ozone for Seoul with data up to the end of 2009. The mean vertical distributions of ozone show that the maximum value of the ozone density is 16.5 DU $km^{-1}$ in the middle stratospheric layer between 24 km and 28 km. About 90.0% and 71.5% of total ozone are found in the troposphere and in the stratosphere between 15 and 33 km, respectively. The trend analysis reconfirms the previous results of significant positive ozone trend, of up to 5% $decade^{-1}$, in the troposphere and the lower stratosphere (0~24 km), with negative trend, of up to -5% $decade^{-1}$, in the stratosphere (24~38 km). In addition, the Umkehr data show a positive trend of about 3% $decade^{-1}$ in the upper stratosphere (38~48 km).

MMS 점군 데이터를 이용한 CCTV의 실질적 감시영역 추출 (Creation of Actual CCTV Surveillance Map Using Point Cloud Acquired by Mobile Mapping System)

  • 최원준;박소연;최윤조;홍승환;김남훈;손홍규
    • 대한원격탐사학회지
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    • 제37권5_3호
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    • pp.1361-1371
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    • 2021
  • 스마트 시티 서비스 중 방범·방재 분야가 2018년 기준 가장 높은 24%를 차지하고 있으며, 실시간 상황정보제공에 가장 중요한 플랫폼은 CCTV(Closed-Circuit Television) 이다. 이러한 CCTV의 활용을 극대화 하기 위해서는 CCTV가 제공하는 실질적인 감시 영역을 파악하는 것이 필수적이다. 하지만 국내에 설치된 CCTV양은 지자체 관리대상 포함 100만대를 넘고 있다. 이러한 방대한 양의 CCTV의 가시영역을 수동적으로 파악해야 하는 것은 문제점으로 제기되고 있다. 이에 본 연구에서는 CCTV의 실질적 가시권 영역 데이터를 효율적으로 구축하고, 관리자가 상황 파악에 소요되는 시간을 단축하는 방안을 제시하고자 하였다. 이를 위하여 첫째, 접근이 어려운 기 설치된 CCTV 카메라의 외부표정요소와 초점 거리를 MMS(Mobile Mapping System)의 점군 데이터를 활용하여 계산하고, 이 결과를 활용하여 FOV(Field of View)를 계산하였다. 둘째, 첫 단계에서 계산된 FOV 결과를 이용하여 건물에 의하여 발생하는 폐색 영역을 고려하여 CCTV의 실질적 감시 영역을 그리드 단위 1 m, 2 m, 3 m, 5 m, 10 m 폴리곤 데이터로 구축하였다. 이 방법을 경상북도 울진군에 위치한 5개소의 CCTV 영상에 적용한 결과, 평균 재투영 오차는 약 9.31 pixel, 공공데이터포털(Data Portal)에서 제공하는 위·경도 좌표와의 거리는 평균 약 10 m의 거리 차이가 발생하였고, MMS를 통해 취득한 점군 데이터 상의 CCTV 위치 좌표 값과는 평균 약 1.688 m의 위치 차이를 나타냈다. 단위 그리드의 한 변의 크기가 3 m인 경우, 본 연구를 통하여 계산된 감시 영역 폴리곤은 육안으로 확인한 실제 감시 영역과 최소 70.21%에서 최대 93.82%까지 일치함을 확인할 수 있었다.