• 한방재활의학과학회지
• /
• 제23권2호
• /
• pp.163-174
• /
• 2013

Restless legs syndrome(RLS) is a neurological disorder characterized by an irresistible urge to move legs to stop uncomfortable or odd sensations. We report a new approach to improve RLS using acupuncture and massage on iliopsoas Muscle. The patients who have RLS were treated by acupuncture and massage on iliopsoas Muscle. We measured 3~6 times IRLS(Korean Versoin of International Restless Legs Scale), VAS(visual analogue scale), and angle(between the legs and the table) during the treatment period. After treatment, RLS symptoms decreased, In case 1, IRLS changed 34 to 10, VAS changed 8 to 2, angle changed 20 to 5. In case 2, IRLS changed 22 to 12, VAS changed 10 to 5, angle changed 15 to 10. In case 3, IRLS changed 30 to 9, VAS changed 8 to 1, angle changed 25 to 5. Acupuncture and massage on iliopsoas muscle for RLS was effective. To effective acupuncture treatment for RLS, more research is needed.

• 사상체질의학회지
• /
• 제27권4호
• /
• pp.419-428
• /
• 2015

Objectives The aim of this study was to report an improvement on the symptoms of Restless Legs Syndrome (RLS) after using Hyeongbangsabaeksan.Methods The patient was diagnosed with Soyangin Soyang-sangpung Symptomatology and treated with Hyeongbangsabaeksan. The patient's subjective symptoms of pain on the lower limb and discomfort in sleeping were observed using the Numerical Rating Scale(NRS) and Visual Analogue Scale(VAS) respectively during the treatment period. And other specific symptoms of RLS were assessed once per week for a total of three times with Korean Versions of the International Restless Legs Scale.Results and Conclusions The pain on the patient's lower limb decreased from NRS 4 to NRS 0 after one week of treatment. And discomfort in sleeping decreased from VAS 5.5 to VAS 0 after one week of treatment. Furthermore, the score of Korean Versions of the International Restless Legs Scale decreased from 40 to 5 after two weeks of treatment. In conclusion, this study shows that Sasang Constitutional Medicine can be an effective treatment for Soyangin patient with Restless Legs Syndrome as Soyangin Soyang-sangpung Symptomatology.

• 대한상한금궤의학회지
• /
• 제11권1호
• /
• pp.125-138
• /
• 2019

Objective : This study was intended to evaluate if treatment with Osuyu-Tang following the disease pattern identification diagnostic system based on Shanghanlun provisions (DPIDS) worked analyzing the progress of patients with migraine and restless legs syndrome and to reinterpret the provision of 309 Soyinbing Osuyu-Tang based on the analysis of whether it worked. Methods : Two cases treated with Soyinbing Osuyu-Tang were analyzed using DPIDS. The migraine and restless legs syndrome in both cases were evaluated using the migraine disability assessment (MIDAS) and the Korean versions of the international restless legs scale (K-IRLS), respectively. Results : In the first case, during 45 days of treatment, the MIDAS decreased from 10 days to 3 days. In the second case, during 30 days of treatment, the K-IRLS decreased from 30 to 9. In both cases, Soyinbing was associated with the disease, although the activity was less; and Leng (冷) was associated with numbness in the kneeling position. Conclusions : It was confirmed that treatment with Osuyu-Tang was effective against migraine and restless legs syndrome and that Leng could be associated with numbness in the kneeling position. The etymological analysis of the Shanghanlun characters suggested the possibility of further clarifying the clinical significance and interpretation of Shanghanlun.

• 수면정신생리
• /
• 제14권2호
• /
• pp.99-106
• /
• 2007

목 적：혈액투석을 받고 있는 만성신부전 환자들에서 하지불안증후군(restless legs syndrome, RLS)의 발생빈도와 삶의 질과의 관계에 대한 연관성을 평가하는 것을 목적으로 하였다. 방 법：고대안암병원 인공신장실에서 만성신부전증으로 혈액투석 중인 83명의 환자들을 대상으로 직접 면담과 설문지를 통해 International Restless Legs Syndrome Study Group(IRLSSG) 진단기준에 합당한 지를 검사하였고 International Restless Legs Scale(IRLS), Athens insomnia scale(AIS), Epworth sleepiness scale(ESS), Medical Outcome Study Short Form-36(SF-36)을 설문지를 통해 측정하였다. 또한 각 환자들의 정신적 상태와 우울증에 대한 선별을 위해 Clinical Global Impression(CGI)와 Hamilton Depression Rating Scale(HDRS)을 시행하였다. 결 과：31명(37.3%)이 IRLSSG 진단기준에 합당한 RLS 환자로 판명이 되었고 RLS 증상을 가지는 환자들은 51.8%에 이르렀다. RLS로 판정된 경우에는 높은 AIS, ESS, HDRS, CGI 점수와 통계적으로 유의한 관련성이 있었다. 또한 RLS 환자로 판정된 경우 낮은 SF-36 총점, 신체적 정신적 요소 점수를 보였고 특히 세부항목으로는 낮은 신체적 역할 제한, 전반적인 건강상태, 신체적 역할제한, 정신적 역할제한, 정신건강 점수와 통계적으로 유의한 관련성이 있었다. 결 론：혈액투석을 하는 만성신부전 환자에서 높은 RLS 유병률을 보이고 있다. RLS를 동반한 경우는 동반하지 않은 경우보다 전반적인 삶의 질의 저하를 보였고 세부적으로는 역할의 제한, 전반적인 건강 및 정신건강 상태 항목에서의 저하가 뚜렷하게 나타났다.

• 대한한방내과학회지
• /
• 제40권2호
• /
• pp.270-278
• /
• 2019

Objective: In this case report, we address the case of a 68-year-old woman with numbness in both soles due to restless legs syndrome. Methods: A patient was treated with Korean medicine including herbal medication Gyejibokryeong-hwan during 73 days as an outpatient. We evaluated the improvements of symptoms by use of the International Restless Legs Scale (IRLS) and checking subjective symptoms of patient. Results: After 73 days of Korean medicine treatment, there was improvement in patient's symptoms. IRLS score improved from 12 to 8, and subjective symptoms improved to about 30% compared to the first time. Conclusions: This study suggested that Korean medicine treatments might be effective in RLS patient recovery.

• Journal of Acupuncture Research
• /
• 제40권4호
• /
• pp.308-318
• /
• 2023

To determine the effectiveness of acupuncture in treating restless legs syndrome (RLS), we conducted a literature review of randomized controlled trials (RCTs) that utilized acupuncture as an intervention for patients diagnosed with RLS. Relevant clinical studies (n = 158) from seven databases (the Cochrane Library, PubMed, Embase, CNKI, KISS, RISS, and OASIS) were included based on the inclusion and exclusion criteria and analyzed. Moreover, 6 RCTs were selected for review. In all six studies, it was indicated people who underwent acupuncture treatment showed significant improvements in their overall health. An increase in the treatment efficacy rate, sleep quality, and quality of life indicators after the acupuncture treatment was confirmed. The severity of pain as assessed using the visual analog scale (VAS) scores and International RLS Study Group Rating Scale (IRLSRS) scores and the severity of RLS symptoms were significantly reduced. Any significant side effects were not reported. Acupuncture is suggested as an effective and safe treatment method for RLS. However, further large-scale RCT studies are needed to confirm our findings.

• 수면정신생리
• /
• 제20권1호
• /
• pp.35-40
• /
• 2013

목 적: 임상실제에서 하지불안증후군(restless legs syndrome, RLS) 환자들의 수면다원검사 결과의 특징과 약물치료의 현황을 자연적인 후향성 연구로 조사하는 것이다. 방 법: 임상적으로 RLS의 진단기준을 만족하며 수면다원검사를 시행 받고 치료받은 18세 이상 환자들의 의무기록을 검토하여 분석하였다. 대상자들에 대해 초진시 International Restless Legs Syndrome Study Group(IRLSSG)의 4가지 진단기준과 국제하지불안척도(International Restless Legs Scale, IRLS)를 평가하고 야간수면다원검사와 제안부동검사(suggested immobilization test, SIT)를 시행하였고, 도파민효현제로 한 달간 약물치료 후 IRLS를 재평가하였다. 결 과: 분석에 포함된 총 대상자수는 211명으로 남자가 94명(44.5%), 여자가 117명(55.5%)이었고 평균연령은 46.9세였다. 폐쇄성수면무호흡증이 136명(64.5%), PLMD가 53명(25.1%)에서 동반되어 다른 수면장애를 동반한 환자의 수는 185명(87.7%)이었다. 수면다원검사결과 수면효율은 78.0%, 수면중각성시간(wake after sleep onset)는 86.8분, N3는 3.4%였다. 평균 무호흡저호흡지수(apnea hypopnea index)는 시간당 12.4회, PLMS는 시간당 14.8회, SIT 중 PLMW는 시간당 41.2회였다. 수면중 총 각성지수는 시간당 21.6회였다. 전체 환자 중 ropinirole을 복용한 환자는 149명(70.6%), pramipexole을 복용한 환자수는 47명(22.3%)이었고 ropinirole은 평균 0.9 mg(용량범위 0.125~5 mg), pramipexole은 평균 0.5 mg(용량범위 0.125~4 mg)을 사용하였다. Ropinirole의 용량은 연령과 유의한 양의 상관관계를 보였고(r=0.25, p=0.002), IRLS와도 유의한 양의 상관관계를 보였다(r=0.23, p=0.038). IRLS는 초진시 24.9점에서 1달 뒤 13.4점으로 감소하였다. 결 론: 본 연구의 분석결과 임상적으로 RLS 진단이 가능한 환자 중에 다른 수면장애를 동반하는 경우가 대다수였다. PLMD에 해당되는 사람은 25.1%로 기존 보고보다 적었고 평균 PLMS도 시간당 14.8회로 높지 않았다. 사용하는 도파민효현제의 용량은 한국에서 허가용량으로 승인받은 용량보다 더 높은 경우가 많았다. 향후 이 주제에 대한 전향적이고 통제된 대규모의 연구가 필요하다.

• 대한중풍순환신경학회지
• /
• 제22권1호
• /
• pp.1-10
• /
• 2021

■ Objectives The purpose of this case study is to report the effectiveness of Gami Ssanghwa-tang on the restless legs syndrome patient. ■ Methods The patient was treated with Korean medicine, including herbal medication Gami Ssanghwa-tang for 26 days and acupuncture for once a week as an out patient. The evaluation was performed using the Korean versions of the International Restless Legs Scale(K-IRLS). ■ Results After 34 days of treatment, the K-IRLS total score improved from 24 to 8. And at the follow up session(7 days after end of treatment), the K-IRLS total score improved to 0. ■ Conclusion This study suggested that herbal medicine, Gami Ssanghwa-tang might be effective in Restless legs syndrome.

• 수면정신생리
• /
• 제15권1호
• /
• pp.39-43
• /
• 2008

목 적 : 하지불안증후군(restless legs syndrome ; RLS)의 병인은 아직 불명확하지만, 도파민 결핍과 유전적 소인이 흔히 제기된다. RLS는 도파민수용체를 차단하는 항정신 병약물을 복용하는 환자들에서 더 흔히 발생하는 것으로 보인다. 본 연구에서는 정신분열병환자에서 항정신병약물에 의해 유발된 RLS와 도파민 수송체(dopamine transporter gene ; DAT1) 유전자가 연관이 있는지 알아보고자 하였다. 방 법: International Restless Legs Syndrome Study Group의 진단기준으로 190명의 한국인 정신분열병 환자들을 대상으로 RLS에 대해서 평가하였다. 유전자형분석은 중합효소연쇄반응기법을 사용하여 DAT1 유전자의 40 염기쌍(basepair) variable number of tandem repeat(VNTR)에 대해서 시행되었다. 결 과 : 우리는 44명의 RLS군과 146명의 비RLS군으로 환자들을 분류하였다. 두 군간의 유전자형과 대립유전자 빈도의 차이를 분석한 결과 유의한 차이를 발견할 수 없었다. 결 론 : 이 연구는 DAT1 유전자의 40 bp VNTR 다형성이 항정신병약물로 유발된 RLS와 연관이 없다는 것을 시사한다. 이 결과를 확증하기 위해서는 향후 보다 대규모의 연합연구가 필요할 것이다.

• 대한한방내과학회지
• /
• 제42권5호
• /
• pp.991-1000
• /
• 2021

Objective: This study examined the effectiveness of Korean medical treatment for an 81-year-old female patient with pontine infarction complaining of discomfort in both legs. Methods: The patient was hospitalized for 45 days and treated with herbal medicine (mainly Bohyulanshin-tang [補血安神湯], pharmacopuncture, acupuncture, electroacupuncture, and moxibustion). We used the International Restless Legs Scale (IRLS) and Numerical Rating Scale (NRS) and checked the duration of the symptoms to evaluate the clinical effects of the treatment. Results: After 45 days of hospitalization, the IRLS score decreased from 33 to 19, with the lowest score of 8 recorded on the twenty-seventh day after discharge. The NRS score and the duration of symptoms also improved, and the treatment effect continued following discharge. Conclusions: This study suggests that Korean medical treatment may be effective for the treatment of restless legs.