• 제목/요약/키워드: Internal standard method

검색결과 696건 처리시간 0.029초

Development of a high-performance liquid chromatographic method for the determintion of levosulpiride in plasma

  • Ban, Eun-Mi;Jang, Dong-Jin;Kim, Adele;Park, Jeong-Sook;Kim, Chong-Kook
    • 대한약학회:학술대회논문집
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    • 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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    • pp.400.3-401
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    • 2002
  • Levosulpiride is the levo-enantiomer from of racemic sulpride. abenzamide derivative selectively inhibition doparninergic D2 receptos at the trigger zone both in the central nervous system and in the gastrointestinal tract. We report a rapid and sensitive HPLC method using reverse phase C 18 column with fluorescence detection for separation and quantitation of levosulpiride in plasma. Tiapride was used as an internal standard. After adding an internal standard. levosulpiride in 800 ${\mu}l$ of plasma was extracted under basic conditions with ethyl acetate and methylene chloride. (omitted)

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모래다짐말뚝의 품질평가 방법과 프로그램의 개발 (Development of a quality evaluation method and computer program of Sand Compaction Pile)

  • 전흥수;임종철;강연익;권정근;주인곤
    • 한국지반공학회:학술대회논문집
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    • 한국지반공학회 2009년도 세계 도시지반공학 심포지엄
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    • pp.1132-1140
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    • 2009
  • Recently soil improvement methods are using in many ways such as costal and soft ground of inland. Among them, sand compaction pile be widely used because of quiet few advantages. There are two ways for quality evaluation method of sand compaction pile. Especially standard penetration test is used the most general method. However, Current method have problems in that it is not consider the condition of construction site. Therefore this study is propose new quality evaluation method. Relation of N-$\Phi$ is always not fixed but changing by condition of construction site. By through the Laboratory test we can know relationship between relative density and internal friction. Also this study propose revision for effective stress. From these study, we can acquire more accurate and reasonable result than current method.

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전립선비대증 변증도구 개발 기초 연구 (Development of a Basic Standard Tool for Pattern Identification of Benign Prostatic Hyperplasia (BPH))

  • 정호영;이지윤;박양춘;정인철;조충식
    • 대한한방내과학회지
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    • 제38권3호
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    • pp.301-318
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    • 2017
  • Objective: The purpose of this study was to develop a standard tool of pattern identification, which will be applied to clinical research, for benign prostatic hyperplasia. Method: The items and structure of the instrument were based on a review of the published literature in China and Korea. The advisory committee on this study included 11 kidney-endocrine professors of the Korean Medical Colleges Division and 4 Korean medicine doctors who had a doctor's degree in the Kidney-Endocrine Division. The advisory committee was questioned regarding pattern identification importance, symptom weight, treatment importance, changes in the symptoms, rare changes in the symptoms, and frequency of prescriptions regarding benign prostatic hyperplasia. Results: The Korean instrument of pattern identification was completed; it was composed of four questions for benign prostatic hyperplasia. Conclusion: We sincerely look forward to improving the instrument through the continuous clinical studies.

X-線回折法에 의한 國産無煙炭中의 黑鉛含量의 定量分析 (Quantitative Analysis of Graphite Contents in Some Korean Anthracites by X-Ray Diffraction Method)

  • 손무룡;정명수;조성일;구정회
    • 대한화학회지
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    • 제22권2호
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    • pp.105-110
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    • 1978
  • 産地가 다른 22種類의 國産無煙炭에 含有되어 있는 黑鉛의 含量을 internal standard method와 direct method로 定量分析하였다. 두 方法으로 實驗한 分析結果는 約 $\pm$ 3%內에서 잘 一致하였다. 各 試料中에 含有되어 있는 無定形炭素와 黑鉛性炭素의 含量比는 地域別로 多小 差異가 있으며 聞慶地區가 14${\sim}$24%,大川地區가 12${\sim}$14%, 江原地區가 3${\sim}$5%로서 江原地區에서 産出되는 無煙炭中의 黑鉛含量이 가장 적음을 알 수 있다.

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다단식 보강토 옹벽 설계사례에 관한 고찰 (A Case Study on Design of Geosynthetic-Reinforced Segmental Retaining Walls)

  • 박시삼;조삼덕;박두희;장기수
    • 한국지반공학회:학술대회논문집
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    • 한국지반공학회 2008년도 추계 학술발표회
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    • pp.168-175
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    • 2008
  • The method of reinforced earth walls has grown remarkably and the frequency of utilization has been increased on a national scale thereafter introduced in the middle 1980s in Korea. Furthermore the construction case of the extensive Geosynthetic-Reinforced Segmental Retaining Walls had been increased. Currently, the design criterion of FHWA and NCMA mainly used in Korea suggest determining the horizontal distance of the upper/lower retaining wall based on the study results of the internal stability and the external stability of Segmental Retaining Walls but in many cases are not suitable for the actual situation in Korea. Therefore, in this study reviewed the design criterion of Geosynthetic-Reinforced Segmental Retaining Walls, performed the internal and external stability in Paju, Gyeonggi-do based on the design criterion of FHWA and NCMA, suggested the modified design criterion of FHWA with analyzing the results, and performed the stability analysis for the internal and external stability and the compound failure. Moreover for the confirmation of the modified FHWA design standard, the suggestion and the analysis of the numerical analysis approaching method using shear strength reduction technique were performed and the design cases utilized the modified FHWA design standard based on the study analysis were introduced.

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X-선 분말 회절법을 이용한 소결광 구성광물상의 정량분석 (Quantitative analysis of iron ore sinter by X-ray powder diffraction method)

  • 김덕남;김형순
    • 한국결정성장학회지
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    • 제10권3호
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    • pp.264-270
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    • 2000
  • 소결광을 구성하는 광물상(hematite, magnetite, calcium ferrite, slag)들을 X선 내부표준법을 이용하여 정량분석을 하였다. 분석에는 표준물질로 NaF와 SiO$_2$를 선택하여 교정곡선을 작성하여 내부표준법에 적용하였다. 소결광내에 존재하는 calcium ferrite는 순수 CF(CaO.$Fe_2$$O_3$에 X선 회절피크는 나타나지 않았으며, 순수 $CF_2(CaO.$2Fe_2$$O_3$)에 근접하였으나 CF2에 소량의 $Al_2$$O_3$$SiO_2$가 고용된 4원계($Fe_2$$O_3$-CaO-$AI_2$$O_3$-$SiO_2$)에 보다 더 근접한 것으로 나타났다. 합성소결광의 정량분석은 두 표준물질 모두 상대오차가 $\pm$5 wt% 내에서 일치하였다. 실제 소결광의 정량분석결과 hematite는 27~40 wt%, magnetite는 20~30 wt%, calcium ferrite 22~33 wt%, slag 10~20 wt% 범위에서 분포하였다.

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Analysis of three dimensional equivalent static wind loads of symmetric high-rise buildings based on wind tunnel tests

  • Liang, Shuguo;Zou, Lianghao;Wang, Dahai;Huang, Guoqing
    • Wind and Structures
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    • 제19권5호
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    • pp.565-583
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    • 2014
  • Using synchronous surface pressures from the wind tunnel test, the three dimensional wind load models of high-rise buildings are established. Furthermore, the internal force responses of symmetric high-rise buildings in along-wind, across-wind and torsional directions are evaluated based on mode acceleration method, which expresses the restoring force as the summation of quasi-static force and inertia force components. Accordingly the calculation methods of equivalent static wind loads, in which the contributions of the higher modes can be considered, of symmetric high-rise buildings in along-wind, across-wind and torsional directions are deduced based on internal forces equivalence. Finally the equivalent static wind loads of an actual symmetric high-rise building are obtained by this method, and compared with the along-wind equivalent static wind loads obtained by China National Standard.

콘칼로리미터를 사용한 샌드위치패널 연소특성에 대한 실험적 연구 (The Experimental Study for the Combustion-Property of Sandwich Panels using ISO 5660 Cone Calorimeter)

  • 박수영;김대회;임홍순
    • 한국화재소방학회논문지
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    • 제20권4호
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    • pp.33-41
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    • 2006
  • 국내에서는 현재 샌드위치패널의 화재안전성능 평가를 위하여 KS F 2271(건축물의 내장재료 및 구조의 난연성 시험방법)을 사용하고 있다. 국내와 동일한 시험방법을 사용하고 있던 일본에서는 2000년 건축기준법 개정시 ISO 5660-1 시험방법을 내장재의 연소성능시험으로 채택하였다. 그에 따라 국내에서도 KS F 2271 시험방법을 보완하는 건축법 개정고시(안)을 예고하였고, 그 내용은 ISO 5660-1(Cone Calorimeter Method) 시험방법을 도입하는 것으로 알려져 있다. 본 연구에서는 샌드위치패널의 연소특성을 ISO 5660-1 콘칼로리미터 시험방법을 사용하여 검토하였다. 국내에서 일반적으로 사용되는 4종의 샌드위치패널과 4종의 심재(단열재)의 착화시간, 최대열방출율, 총 열방출량을 검토하였으며, 시험체별 시험결과를 분석하였다. 최종적으로 일본과 NBC개정안에서 제시하는 분류기준에 시험결과를 적용하였다.

유리 복부 피판 유방재건술에서 늑연골을 절제하지 않는 Internal mammary vessel로의 접근법 (Approach to Internal Mammary Vessel without Rib Cartilage Resection in Free Abdominal Flap Breast Reconstruction)

  • 엄진섭;선상훈;김태곤;이택종
    • Archives of Plastic Surgery
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    • 제36권6호
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    • pp.750-754
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    • 2009
  • Purpose: The thoracodorsal vessels have been the standard recipient vessels for the majority of surgeons performing free abdominal flap breast reconstructions. Recently, the internal mammary vessels have been recommended as the first - choice recipient vessels for microvascular breast reconstruction. To approach the internal mammary vessel, 3rd or 4th rib cartilage excision is needed, but this method has some demerits - vessel injury, post operative pain and post operative chest hollowness. So, authors propose the approach method to the internal mammary vessel through intercostal space without rib cartilage resection. Methods: From November, 2008 to May, 2009, 13 patients underwent free abdominal flap breast reconstruction with approach to the internal mammary vessel through intercostal space without rib cartilage resection. Results: The mean patient age was 41.8 years, and the mean height was 159.3 cm. 11 patients underwent immediate breast reconstruction. Free DIEP flap reconstruction was performed in 7 patients, Free TRAM flap was performed in 5 patients, and Free SIEA flap was performed in 1 patient. Except 1 case, approach to the internal mammary vessel was took through 3rd intercostal space, and all width of intercostal space exceeded 1 cm. Conclusion: In the authors' experience, use of approach to the internal mammary vessels without rib cartilage resection method is safe and reliable to overcome demerits of rib cartilage resection method.