• Title/Summary/Keyword: Internal problems

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입효산(立效散)의 Methicillin-Resistant Staphylococcus aureus에 대한 항균활성에 관한 연구 (Antibacterial Effect of Ipyo-san against Methicillin-Resistant Staphylococcus aureus)

  • 윤재홍;최연주;정승현;신길조
    • 대한한방내과학회지
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    • 제34권3호
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    • pp.278-288
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    • 2013
  • Objectives : Methicillin-resistant Staphylococcus aureus (MRSA) has a cephalosporin and beta-lactam antibiotic-resistant strains. MRSA is one of the major pathogens causing hospital infection and the isolation ratio of MRSA has gradually increased. Consequently, increased resistance to antibiotics is causing serious problems in the world. Therefore, there is a need to develop alternative antimicrobial drugs for the treatment of infectious diseases. Methods : The antibacterial activities of Ipyo-san were evaluated against 2 strains of MRSA and 1 standard Methicillin-susceptible staphylococcus aureus (MSSA) strain by using the disc diffusion method, minimal inhibitory concentrations (MIC) assay, colorimetric assay using MTT test, checkerboard dilution test and time-kill assay performed under dark. Results : The MIC of Ipyo-san water extract against S. aureus strains ranged from 1000 to $2,000{\mu}g/ml$, so we confirmed that it had a strong antibacterial effect. Also, the combinations of Ipyo-san water extract and conventional antibiotics exhibited improved inhibition of MRSA with synergy effect. We suggest that Ipyo-san water extract against MRSA has antibacterial activity so it has potential as alternatives to antibiotic agents. For the combination test, we used Triton X-100 (TX) and DCCD for measurement of membrane permeability and inhibitor of ATPase. As a result, antimicrobial activity of Ipyo-san water extract was affected by the cell membrane. Conclusions : We suggest that the Ipyo-san water extract lead the treatment of bacterial infection to solve the resistance and remaining side-effect problems that are the major weak points of traditional antibiotics.

LED 칩 제조용 사파이어 웨이퍼 절단을 위한 내부 레이저 스크라이빙 가공 특성 분석 (Analysis of Cutting Characteristic of the Sapphire Wafer Using a Internal Laser Scribing Process for LED Chip)

  • 송기혁;조용규;김병찬;강동성;조명우;김종수;유병소
    • 한국산학기술학회논문지
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    • 제16권9호
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    • pp.5748-5755
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    • 2015
  • 스크라이빙 공정은 LED 칩 생성을 위한 절단 공정으로 칩의 특성 및 생산량을 결정하는 중요한 공정이다. 기존의 기계적 방식 및 레이저 방식의 스크라이빙 공정은 칩의 열 변형 및 강도 저하, 절단 영역의 제한 등의 문제점이 있다. 이러한 문제를 해결하기 위해 웨이퍼 내부에 공극을 생성하여 자가 균열을 유도하는 내부 레이저 스크라이빙 공정이 연구되고 있으나 LED 칩 제작을 위한 사파이어 웨이퍼의 절단에 대한 연구는 미비한 실정이다. 본 논문은 LED 칩 제작에 사용되는 사파이어 웨이퍼의 내부 레이저 스크라이빙 공정을 적용하기 위해 주요 가공 변수를 정립하고 가공 실험을 통하여 절단 특성을 분석함으로써 내부 레이저 스크라이빙 시스템 구축을 위한 기초 가공 조건을 확립하였다.

억간산(抑肝散) 가미방(加味方)으로 증상 호전 보인 진전 환자 1례에 대한 증례 보고 (A case study of tremor patient with Yeokgansan-gamibang)

  • 임승민;안정조;최병렬;송기철;김만호;김윤식;설인찬
    • 대한한방내과학회지
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    • 제24권2_4호
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    • pp.1062-1066
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    • 2003
  • Tremor is a rhythmic and involuntary muscular contraction characterized by oscillations of body parts. Tremor often accompanies neurological disorders associated with aging. Although the disorder is not life-threatening, it can be responsible for functional disability and interpersonal relationship problems. We have recently examined a number of tremor-patients. one of them was improved significantly through the herbal medicine (Yeokgansan-gamibang) and acupuncture, so we report it for the better treatment.

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위절제술후 증후군에 대한 증례 2례 (Two Cases of Postgastrectomy Syndrome Treatment with Oriental Medicine)

  • 류지철;김영균;권정남
    • 대한한방내과학회지
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    • 제25권3호
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    • pp.596-601
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    • 2004
  • After a gastrectomy, various forms of postgastrectomy syndrome may happen, such as dumping syndrome, reflux $^{\wedge}esophagitis$, afferent loop syndrome, marginal ulcer, anemia, etc. These can cause some problems in the quality of life for post-gastrectomy patients. This oriental medicine treatment was designed to improve digestion and relieve symptoms, correct imbalance and prevent relapse in each case. This study suggests a level of efficacy of oriental medicine(Samryungbaekchul-san, Bobi-tang) in treating postgastrectomy syndrome.

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Internal Structure of Information Packages in Digital Preservation

  • Lee, Seungmin
    • Journal of Information Science Theory and Practice
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    • 제2권4호
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    • pp.6-19
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    • 2014
  • The description of preserved resources is one of the requirements in digital preservation. The description is generally created in the format of metadata records, and those records are combined to generate information packages to support the process of digital preservation. However, current strategies or models of digital preservation may not generate information packages in efficient ways. To overcome these problems, this research proposed an internal structure of information packages in digital preservation. In order to construct the internal structure, this research analyzed existing metadata standards and cataloging rules such as Dublin Core, MARC, and FRBR to extract the core elements of resource description. The extracted elements were categorized according to their semantics and functions, which resulted in three categories of core elements. These categories and core elements were manifested by using RDF syntax in order to be substantially applied to combine metadata records in digital preservation. Although the internal structure is not intended to create metadata records, it is expected to provide an alternative approach to enable combining existing metadata records in the context of digital preservation in a more flexible way.

파두 투여 후 호전된 뇌경색 환자의 장마비 치험 1례 (A case report of stroke patient with ileus treated with Crotonis Fructus(巴豆))

  • 양나래;권영주;조우근;최동준;한창호
    • 대한중풍순환신경학회지
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    • 제11권1호
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    • pp.99-104
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    • 2010
  • Paralytic ileus is one of the common complications in stroke patients. In western medical treatment, surgery or conservative care is used for treating ileus. In this case, patient diagnosed as paralytic ileus had problems of constipation, or abdominal distension. Therefore the patient were treated with Crotonis Fructus(巴豆), and the patient showed improvement in X-ray findings and these symptoms. So we report this case.

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창포울금탕(菖蒲鬱金湯)으로 호전된 중풍환자 불면증(不眼症) 치험 2례 (Two Cases of Insomnia in Stroke Patiens Treated with Changpoulgeumtang)

  • 오용성;임명현;장우석;이소연;박치상;박창국
    • 대한한방내과학회지
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    • 제24권2_4호
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    • pp.1055-1061
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    • 2003
  • Insomnia is a disorder of initiation and maintenance of sleep that is derived from multiple factors such as psychologic, physiological and environmental problems. A number of stroke patients suffer from insomnia classified as one of the sleep disorders associated with physical illness and on the contrary insomnia may have profound deleterious effects on the natural course of stroke. Sedative-hypnotics including benzodiazepine and non-benzodiazepine have widely been used in chronic insomniacs. However, most hypnotics cause dependence, tolerance, impaired daytime function and rebound insomnia. Therefore, we are looking forward to proposing an effective oriental treatment for insomnia. We report two cases of insomniacs, treated with Changpoulgeumtang. After the treatment, insomnia and other accompanied symptoms were improved.

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