• 제목/요약/키워드: Internal membrane

검색결과 537건 처리시간 0.032초

Clinical outcomes and characteristics of acute myocardial infarction patients with developing fever after percutaneous coronary intervention

  • Jae-Geun Lee;Yeekyoung Ko;Joon Hyouk Choi;Jeong Rae Yoo;Misun Kim;Ki Yung Boo;Jong Wook Beom;Song-Yi Kim;Seung-Jae Joo
    • Journal of Medicine and Life Science
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    • 제19권2호
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    • pp.46-56
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    • 2022
  • The incidence of fever complicating percutaneous coronary intervention (PCI) is rare. However, little is known regarding the cause of fever after PCI. Therefore, this study aimed to determine the clinical characteristics of patients with acute myocardial infarction (AMI), with or without fever, after PCI. We enrolled a total of 926 AMI patients who underwent PCI. Body temperature (BT) was measured every 4 hours or 8 hours for 5 days after PCI. Patients were divided into two groups according to BT as follows: BT<37.7℃ (no-fever group) and BT ≥37.7℃ (fever group). The 2 years clinical outcomes were compared subsequently. Fever after PCI was associated with higher incidence of major adverse cardiac events (MACE) (hazard ratio [HR], 1.56; 95% confidence interval [CI], 1.07-2.28; P=0.021), all-cause death (HR, 2.32; 95% CI, 1.18-4.45; P=0.014), cardiac death (CD) (HR, 2.57; 95% CI, 1.02-6.76; P=0.049), and any revascularization (HR, 1.69; 95% CI, 1.02-2.81; P=0.044) than without fever. In women, prior chronic kidney disease, lower left ventricular (LV) ejection fraction, higher LV wall motion score index, white blood cell count, peak creatine kinase-myocardial band level, and longer PCI duration were associated with fever after PCI. Procedures such as an intra-aortic balloon pump, extracorporeal membrane oxygenation, continuous renal replacement therapy, central and arterial line insertion, and cardiopulmonary resuscitation were related to fever after PCI. Fever after PCI in patients with AMI was associated with a higher incidence of MACE, all-cause death, CD, and any revascularization at the 2 years mark than in those without fever.

Plasma Protein Adsorption to Anion Substituted Poly(vinyl alcohol) Membranes

  • Ryu, Kyu-Eun;Hyangshuk Rhim;Park, Chong-Won;Chun, Heung-Jae;Hong, Seung-Hwa;Kim, Jae-Jin;Lee, Young-Moo
    • Macromolecular Research
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    • 제11권6호
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    • pp.451-457
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    • 2003
  • Anion-substituted poly(vinyl alcohol) (PVA) membranes, carboxymethylated PVA (C-PVA), and sulfonated PVA (S-PVA) were prepared and the effects of these substitutions on the plasma protein adsorption were studied by one- and two-dimensional gel electrophoresis and immunoblotting. When Cuprophane was used as a negative control, the amount of total proteins bound to samples decreased in the order Cuprophane > PVA > C-PVA > S-PVA, which we attribute to the effects of the surface characteristics of the samples, such as their surface tensions and electrostatic properties, on the adsorption of proteins to the surfaces of the materials. The results revealed that albumin was the most abundant protein in all the samples. The proportion of adsorbed fibrinogen to S-PVA exceeded those of PVA and C-PVA, whereas S-PVA exhibited the lowest IgG adsorption affinity among the samples we studied.

Indomethacin으로 유발된 생쥐의 위 점막 손상에 대한 향사평위산(香砂平胃散)의 보호 효과 (The Effects of Hyangsapyeongwisan on Gastric Mucosal Lesions Induced by Indomethacin)

  • 최흥민;임성우
    • 대한한방내과학회지
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    • 제25권3호
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    • pp.518-528
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    • 2004
  • This study was carried out to investigate the effects of Hyangsapyeongwisan(HP) on gastric mucosal lesions induced by indomethacin in mice. The control group consisted of gastro-inflammation elicited mice. The sample group consisted of mice given HP after onset of gastro-inflammation. In common morphological and histochemical change, various cell abnormalities were observed in the control group, such as mucous surface cell, peanut cell, surface epithelial cell, goblet cell abnormalities, all caused hemorrhagic erosion. The sample group was the same as the control group. In the immunohistochemical change, the distributions of COX-I, BrdU treated with HP were notably higher than those of the control group(p$NF-{\kappa}B$, COX-2, PKC, IL-12B in mice treated with HP were notably lower than those of the control group(p

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인체 유방암세포 MDA-MB-231에서 건칠(乾漆) 추출물이 PI3K/AKT 신호경로를 통한 caspase 의존적 apoptosis 유발에 미치는 영향 (Caspase-dependent and Akt-pathway Regulated Rhus Verniciflua Stokes Extract-induced Apoptosis in Human Breast Carcinoma MDA-MB-231 Cells)

  • 홍상훈;박상은
    • 대한한방내과학회지
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    • 제38권4호
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    • pp.409-418
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    • 2017
  • In Korea, Rhus verniciflua Stokes is used to purge hardness, alleviate blood stasis, and treat cancer. However, the mechanisms of related anti-cancer activity are not fully understood in human cancer cells. This study investigated the anti-cancer effects and mechanisms of Rhus verniciflua Stokes on MDA-MB-231 human breast cancer cells and found that treatment with a Rhus verniciflua Stokes extract resulted in time- and concentration-responses that indicated growth inhibition of breast cancer cells by induced apoptosis. This was followed by a decrease in mitochondrial membrane potential; the activation of caspase-3, -8, and -9; and the up-regulation of tBid. Caspase-dependent apoptosis was induced through the inhibition of phosphatidylinositol 3-kinase (PI3K) and the Akt signaling pathway. This study provides evidence that Rhus verniciflua Stokes might be useful for the treatment of breast cancer.

내력상태계수 도입을 통한 RC보의 전단강도분석 (Shear Strength Incorporated with Internal Force State Factor in RC Slender Beams)

  • 정제평;김희정;김우
    • 한국콘크리트학회:학술대회논문집
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    • 한국콘크리트학회 2003년도 봄 학술발표회 논문집
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    • pp.912-917
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    • 2003
  • In this paper a new truss modeling technique for describing the beam shear resistance mechanism is proposed based on the reinterpretation of the well-known relationship between shear and the rate of change of bending moment in a reinforced concrete beam subjected to combined shear and moment loads. The core of the model is that a new perspective on the shear resistance can be gained by viewing the internal stress filed in terms of the superposition of two base components of shear resistance; arch action and beam action. The arch action can be described as a simple tied-arch which is consisted of a curved compression chord and a tension tie of the longitudinal steel, while the beam action between the two chords can be modeled as a membrane shearing element with forming a smeared truss action. The compatibility of deformation associated to the two action is taken into account by employing an experimental factor or internal state force factor a. Then the base equation of V=dM/dx is numerically duplicated. The new model was examined by the 362 experimental results. The shear strength predicted by the internal force state factor a show better correlation with the tested values than the present shear design.

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막응력과 휨을 고려한 RC 쉘의 설계와 극한거동 (Combined membrane and flexural reinforcement design in RC shells and ultimate behavior)

  • 민창식
    • 한국콘크리트학회:학술대회논문집
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    • 한국콘크리트학회 1998년도 가을 학술발표논문집(II)
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    • pp.405-411
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    • 1998
  • An iterative numerical computational algorithm is presented to design a plate of shell element subjected to membrane and flexural forces. Based on equilibrium consideration, equations for capacities of top and bottom reinforcements in two orthogonal directions have been derived. The amount of reinforcement is determined locally, i. e., for each sampling point, from the equilibrium between applied and internal forces. One case of design is performed for a hyperbolic paraboloid saddle shell (originally used by Lin and Scordelis) to check the design strength against a consistent design load, therefore, to verify the adequacy of design practice for reinforced concrete shells. Based on nonlinear analyses performed, the analytically calculated ultimate load exceeded the design ultimate load from 14-43% for an analysis with relatively low to high tension stiffening, ${\gamma}$ =5~20 cases. For these cases, the design method gives a lower bound on the ultimate load with respect to Lower bound theorem. This shows the adequacy of the current practice at least for this saddle shell case studied. To generalize the conclusion many more designs-analyses are performed with different shell configurations.

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Electrospinning Technology for Novel Energy Conversion & Storage Materials

  • 조성무;김동영
    • 한국재료학회:학술대회논문집
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    • 한국재료학회 2011년도 추계학술발표대회
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    • pp.1.1-1.1
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    • 2011
  • Electrospinning has known to be very effective tool for production of versatile one-dimensional (1D) nanostructured materials such as nanofibers, nanorod, and nanotubes and for easily assembly to two-, three-dimensional(2D, 3D) nanostructures such as thin film, membrane, and nonwoven web, etc. We have studied on the electrospinning technology for novel energy storage and conversion materials such as advanced separator, dye sensitized solar cell, supercapacitor, etc. High heat-resistive nanofibrous membrane as a new separator for future lithium ion polymer battery was prepared by electrospinning of PVdF based composite solution. The novel nanofibrous composite nonwovens have tensile strength of above 50 MPa and modulus of above 1.3 GPa. The internal structure of the electrospun composite nanofiber with a diameter of few hundreds nanometer were composed of core-shell nanostructure. And also electrospun $TiO_2$ nanorod/nanosphere based dye-sensitized solar cells with high efficiency are successfully prepared. Some battery performance will be introduced.

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삼초유형(三焦有形)으로 살펴본 삼초(三焦)의 기능(機能), 병증(病證) 및 장부배합(臟腑配合) (Function Disease Symptom And Organ Coordination of Tri-Energizer Based on the Materiality of Tri-Energizer)

  • 윤창열
    • 대한한의학원전학회지
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    • 제26권2호
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    • pp.1-7
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    • 2013
  • Objective & Method : By investigating physiological function of tri-energizer, symptoms, and organ coordination, we obtained following conclusion. Tri-energizer is the membrane structure that surrounds the five visceral organs and six hollow organs, and filled with fluid. Tri-energizer acts as the passage for the flow of qi energy. Result & Conclusion : Therefore, dysfunction of the tri-energizer is caused by abnormal evaporation and metabolism. Upper-energizer regulates cardiopulmonary function, middle-energizer regulates spleen and stomach functions, and lower-energizer regulates liver, kidneys, small and large intestines, and bladder functions. Such a functional specialization is possible by receiving the source of qi through the wall wrapping around the internal organs. Tri-energizer represents the exterior and interior relationship by acting as the membrane structure supporting the five visceral organs and six hollow organs and at the same time, as the pericardium surrounding the heart.

Derivation of design charts based on the two-dimensional structural analysis of geotextile tubes

  • Kim, Hyeong-Joo;Won, Myoung-Soo;Park, Tae-Woong;Choi, Min-Jun;Jamin, Jay C.
    • Structural Engineering and Mechanics
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    • 제55권2호
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    • pp.349-364
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    • 2015
  • Analytical solutions for modeling geotextile tubes during the filling process and approximation method to determine the densified tube shape are reviewed. The geotextile tube filling analysis is based on Plaut & Suherman's two-dimensional solution for geotextile tubes having a weightless and frictionless inextensible membrane resting on a rigid horizontal foundation subjected to internal and external hydrostatic pressures. The approximation for the densified tube shape developed by Leshchinsky et al. was adopted. A modified method for approximating the densified tube shape based on an areal-strain deformation analysis is introduced. Design diagrams useful for approximating geotextile tube measurements in the design process are provided.

물이 인체 건강에 미치는 영향 (Human Health Effects due to Consumption of Low TDS Water)

  • Rozelle, Lee T.
    • 멤브레인
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    • 제6권4호
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    • pp.189-195
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    • 1996
  • It is concluded from this study that human consumption of very low TDS water does not leach minerals from the body that cause ill health effects because; -The human body's own control mechanism of homeostasis and internal body secretions keep tight controls on body fluid composition regardless of drinking water TDS for a normal person under normal csonditions. -The unofficial WHO document's proposed guideline of a 100m/l lower limit for drinking water due to mineral leaching and subsequent ill health was not found to be scientifically or physiologically credible. Leaching of minerals from the body is not officially recognized by WHO. -The experience of the U.S. Navy, Army, NASA and dommunity demonstrations do not support ill health symptoms caused by consumption of low TDS drinking water. -Millions of people regularly consume maturally occurring low TDS water without symptoms of ill health.

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