• Nuclear Engineering and Technology
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• v.38 no.8
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• pp.753-762
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• 2006

In this paper, works related to enhancement of the CHF are reviewed in terms of fundamental mechanisms and practical applications. Studies on CHF enhancement in forced convection are divided into two categories, CHF enhancement of internal flow in tubes and enhancement of CHF in the nuclear fuel bundle. Methods of enhancing the CHF of internal flows in tubes include enhancement of the swirl flow using twisted tapes, a helical coil, and a grooved surface; promotion of flow mixing using a hypervapotron; altering the characteristics of the heated surface using porous coatings and nano-fluids; and changing the surface tension of the fluid using additives such as surfactants. In the fuel bundle, mixing vanes or wire wrapped rods can be employed to enhance the CHF by changing the flow distributions. These methods can be applied to practical heat exchange systems such as nuclear reactors, fossil boilers, fusion reactors, etc.

• Journal of Digestive Cancer Reports
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• v.8 no.1
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• pp.56-60
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• 2020

In recent years, liquid biopsy has received immense attention. Liquid biopsy is a minimally invasive method used for obtaining biological fluids including urine, pleural fluid and, mostly, peripheral blood. Liquid biopsy involves various targets including circulating tumors cells (CTCs), circulating cell-free tumor DNA (ctDNA), and microRNA (miRNA). Colorectal cancer (CRC), like other solid tumors, shed tumor cells into the bloodstream. Analysis of these CTCs, as well as ctDNA is the primary objective of the liquid biopsy. Evaluation of CTC or ctDNA offers information about early tumor release, development of tumor metastasis and also about mechanisms involved in tumor resistance to treatment.

• Journal of Physiology & Pathology in Korean Medicine
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• v.18 no.1
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• pp.289-293
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• 2004

Hantaviruses are found worldwide and are known to cause two serious and often fatal human disease: hemorrhagic fever with renal syndrome(HFRS) and hantavirus pulmonary syndrome(HPS). The typical clinical prodrome consists of fever, chills, myalgia, headache, and gastrointestinal symptoms. Treatment usually involves maintenance of fluids, blood pressure, ventilation and electrolytes. We report a patient who had multisystem inflammatory symptom with Hantaan virus antibody positive accompanied by mild fever and myalgia. This case was diagnosed as HFRS. This patient was treated by Galgun hegi-tang. As a result of this treatment, symptoms were markedly improved.

• Journal of Mechanical Science and Technology
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• v.19 no.11
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• pp.2032-2039
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• 2005

The lattice Boltzman method (LBM) and the finite difference-based lattice Boltzmann method (FDLBM) are quite recent approaches for simulating fluid flow, which have been proven as valid and efficient tools in a variety of complex flow problems. They are considered attractive alternatives to conventional finite-difference schemes because they recover the Navier-Stokes equations and are computationally more stable, and easily parallelizable. However, most models of the LBM or FDLBM are for incompressible fluids because of the simplicity of the structure of the model. Although some models for compressible thermal fluids have been introduced, these models are for monatomic gases, and suffer from the instability in calculations. A lattice BGK model based on a finite difference scheme with an internal degree of freedom is employed and it is shown that a diatomic gas such as air is successfully simulated. In this research we present a 2-dimensional edge tone to predict the frequency characteristics of discrete oscillations of a jet-edge feedback cycle by the FDLBM in which any specific heat ratio $\gamma$ can be chosen freely. The jet is chosen long enough in order to guarantee the parabolic velocity profile of a jet at the outlet, and the edge is of an angle of $\alpha$=23$^{o}$. At a stand-off distance w, the edge is inserted along the centerline of the jet, and a sinuous instability wave with real frequency is assumed to be created in the vicinity of the nozzle exit and to propagate towards the downstream. We have succeeded in capturing very small pressure fluctuations resulting from periodic oscillation of the jet around the edge.

• Biomedical Science Letters
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• v.13 no.4
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• pp.325-332
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• 2007

Cell-mediated immune response (CMI) is a major immune protective mechanism against tuberculosis (TB) infection. Among several components involved in CMI, recent studies suggest that CD8+ T cells are important in controlling TB infection. In our previous report, we defined four Mycobacterium tuberculosis (MTB) derived epiotpe peptides specific for HLA-A*0201-restricted CD8+ T cells. These four peptides are $PstAl_{75-83}$, $ThyA_{30-38}$, $RpoB_{127-135}$ and $85B_{15-23}$. In this study, these epitope peptides specific CD8+ T cell responses in tuberculous pleurisy were investigated using ex vivo $IFN-\gamma$ elispot assay and intracellular $IFN-\gamma$ staining method. As a result, we observed these epitope peptide specific CD8+ T cell responses are induced in all three patients with tuberculous pleurisy suggesting that CD8+ T cells are involved in protective immune mechanism against MTB infection in tuberculous pleurisy. However, the CMI to mitogens and MTB antigens from pleural fluids of patients with tuberculous pleurisy does not seem to correlate with that from peripheral blood, although the sample size is too small to make any conclusion. In sum, the MHC I restricted CD8+ T cell responses seem to be induced efficiently in the pleural fluids, at the site of TB infection, in which the CMI is actively induced. In addition, these experiments suggest that MHC I restricted CD8+ T cell mediated immune responses are also involved in protective mechanism against MTB infection in extra-pulmonary TB.

• Journal of East-West Nursing Research
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• v.16 no.1
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• pp.70-75
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• 2010

Purpose: Nursing students face constant threats of blood-borne infections such as HIV, Hepatitis B, and Hepatitis C during their clinical rotation period. This study was done to determine the frequency and risk of the exposure to blood and body fluids. Methods: The data was collected using a questionnaire. Ninety eight junior & senior nursing students were participated in this study. Results: 75.6% of the participants reported more than once during practicum. The exposure occurred most frequently while checking the blood glucose (65.3%). The general ward (45.3%) was the most frequent site for the occurrence of the exposure. However, only eight cases (10.7%) were reported to the medical or nursing personnel in charge. Conclusions: This study shows nursing students are in a great risk of the exposure to blood & body fluid. The risk is highest in the general ward during checking the blood glucose. Thorough education on preventive measures, should be provided to nursing students prior to clinical practium.

• Journal of the Korean Society of Industry Convergence
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• v.26 no.5
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• pp.803-812
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• 2023

The subsea separator of an offshore plant for offshore oil and gas development performs the process of separating oil and gas from crude oil produced in the subsea. The oil-gas subsea separator can be divided into a gravity type that separates fluids by gravity and an in-line type that separates fluids using centrifugal force of density. In the case of the deep sea, the development of a small in-line type separator is required due to manufacturing cost and safety problems caused by water pressure. Therefore, in this study, the gas-liquid phase separation efficiency of the subsea separator was identified through the study of the multiphase flow characteristics of the in-line type separator. For the optimal design of the in-line type separator, the shape of the internal swirl element(ISE) was selected first, and the separation efficiency results for each section of the in-line type separator were analyzed. This study was conducted in parallel with experiments and numerical analysis, and it is expected that the reliability and efficiency of the in-line type separator will be improved through the results.

• 한국전산유체공학회:학술대회논문집
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• 2005.10a
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• pp.219-222
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• 2005

Recently, the interest of the engine capacity and environment of the atmosphere is increasing, so the researches for the engine capacity have been conducted for a long time. But the internal environment of an automotive engine is very severe. A piston is exposed to combustion gas of over $2000^{\circ}C$ and strong friction is occurred by high speed motion in the cylinder. The fraction between piston and wall of the cylinder causes the increase of temperature in the engine. The temperature of the engine has an effect on the engine capacity. If the temperature is high, the capacity of the engine is low. So we have to maintain the optimum temperature. To maintain the optimum temperature, the enough flow rate of the engine oil is needed. The oil jet is used to control the flow rate of the engine oil and supply the engine oil to the piston and cylinder. The purpose of this study is to check the mass flow rate of the engine oil and the characteristics of internal flow of the oil jet. Flow pattern of the engine oil is very important because it concludes the loss in the oil jet. This study is the previous research about the oil jet and we will consider the movement of the ball check valve to get more accuracy result.

• Journal of the Korean Society of Visualization
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• v.3 no.1
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• pp.3-19
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• 2005

Novel optical techniques are presented for three-dimensional tracking of nanoparticles; Optical Serial Sectioning Microscopy (OSSM) and Ratiometric Total Internal Reflection Fluorescent Microscopy (R-TIRFM). OSSM measures optically diffracted particle images, the so-called Point Spread Function (PSF), and dotermines the defocusing or line-of-sight location of the imaged particle measured from the focal plane. The line-of-sight Brownian motion detection using the OSSM technique is proposed in lieu of the more cumbersome two-dimensional Brownian motion tracking on the imaging plane as a potentially more effective tool to nonintrusively map the temperature fields for nanoparticle suspension fluids. On the other hand, R-TIRFM is presented to experimentally examine the classic theory on the near-wall hindered Brownian diffusive motion. An evanescent wave field from the total internal reflection of a 488-nm bandwidth of an argon-ion laser is used to provide a thin illumination field of an order of a few hundred nanometers from the wall. The experimental results show good agreement with the lateral hindrance theory, but show discrepancies from the normal hindrance theory. It is conjectured that the discrepancies can be attributed to the additional hindering effects, including electrostatic and electro-osmotic interactions between the negatively charged tracer particles and the glass surface.

• Journal of ILASS-Korea
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• v.16 no.2
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• pp.90-96
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• 2011

Atomized liquid jets from the washing nozzle which configured with recirculation chamber for cleaning hot-zone area are accelerated and impinged on the head lamp surface. Cleaning efficiency of head lamp can be increased with injecting washing fluids into the hot-zone area. Experimental and numerical studies with various design parameters were executed to reveal the relations between internal geometry and internal flow in the washing nozzle. Spray structures were fitted with each of the head lamp surfaces and spray nozzles were optimized to the spray pattern. The recirculation chamber induces a recirculation flow and can be decreased the pressures perturbation inside the chamber. Orifice determines the mass flow rate. When the diameter of orifice is excessively large, it showed an unstable spray pattern. As a nozzle exit angle increases, density distributions are separated with two section. Also, as a protrusion length of nozzle exit increases, spray patterns are spread into a large area and density distributions showed unstable trend.