• Pediatric Infection and Vaccine
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• v.25 no.2
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• pp.107-112
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• 2018

Staphylococcus aureus is now a major community-acquired pathogen worldwide, notably associated with skin and soft tissue infections. Staphylococci are present in the form of colonizers or environmental contaminants at home and increase the risk of recurrent infection. We are describing recurrent familial furunculosis caused by Panton-Valentine Leukocidin-positive methicillin susceptible S. aureus ST1 in Korea. An infant, his father and mother had furunculosis due to methicillin-sensitive S. aureus (MSSA) infection with identical susceptibility patterns. ST1 accounted for all 3 isolates and they were confirmed of having agr group I. Both sec and seh were detected in all isolates using polymerase chain reaction (PCR) assays, and all isolates contained Panton-Valentine leukocidin (PVL) genes. Risk factors for the household spread of S. aureus include skin conditions and close physical contact among household members. The relationship between S. aureus colonization of household contacts and the occurrence of S. aureus infection should be studied into more detail.

• Journal of Society of Preventive Korean Medicine
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• v.23 no.3
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• pp.21-30
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• 2019

Objective : The study aimed to report the results of workplace-based Korean Medicine cohort, The cohort collected the health information including physical measurements, questionnaires, and biomarkers. Method : This study was conducted on 200 faculty members of two hospitals and two universities in 2017 through 2018. The study analyzed physical measurement, cold-heat questionnaire, body compositions and pulse characteristics. Result : The heat-cold score, waist circumference, visceral fat area, and body water were different according to the Sasang constitution, in order of Taeum > Soyang > Soeum. The pulse energy difference was shown only in women. Conclusion : There were differences in body composition such as heat point, waist circumference, internal fat area and body water content by constitution, and also difference by body mass in total energy in pulse examination. It is believed that there were significant relation between physical, physical and energy metabolic aspects through Sasang constitution.

• Journal of the Korea Convergence Society
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• v.13 no.1
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• pp.365-373
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• 2022

The purpose of this study is to determine the effect of concurrent appointment as a director on the quality of the internal accounting management system (IACS). For analysis, 9,343 KOSPI & KOSDAQ company-year data from 2014-2019, excluding the financial industry, were used. As a result of the analysis, it was confirmed that the quality of IACS decreased as the number of multiple positions in the director increased. Although there is a difference in the roles of inside and outside directors, it was found that the quality of IACS decreases equally as the number of board members. According to the business hypothesis, this can be said to be the result of the agency problem within the company because directors, who were more busy with concurrent positions as directors, did not put sufficient effort into their work. This study suggests that information on the concurrent position of directors can be a new indicator that reflects the characteristics of the board in evaluating the effectiveness of corporate governance.

• The Journal of Internal Korean Medicine
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• v.37 no.1
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• pp.65-76
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• 2016

Objectives: The purpose of this study was to identify the inhibitory effects of Hwangheuk-san (HHS), a Korean multi-herb formula comprising four medicinal herbs, on cell migration and invasion, two critical cellular processes that are often deregulated during metastasis, using the human bladder cancer 5637 cell line.Methods: Cell viability, motility, and invasion were assessed by 3-(4,5-dimethyl-2 thiazolyl)-2,5-diphnyl-2H-tetrazolium bromide (MTT), wound healing migration, and Transwell assays, respectively. Gene expression was detected by Western blot analysis. In addition, the activities of matrix metalloproteinases (MMPs) and the values for transepithelial electrical resistance (TER) were analyzed using a Gelatinase Activity Assay Kit and an Epithelial Tissue Voltohmmeter, respectively.Results: Our data indicated that within the concentration range that was not cytotoxic, HHS effectively inhibited the cell motility and invasiveness of 5637 cells. HHS markedly decreased the expression and activity of MMP-2 and MMP-9, which was associated with unregulation of tissue inhibitors of metalloproteinase (TIMP)-1 and TIMP-2. Further investigation revealed that phosphorylation of phosphatidylinositol 3-kinase (PI3K) and AKT was decreased in HHS-treated 5637 cells, and a PI3K/AKT inhibitor synergistically reduced the inhibition of migration and invasion and also inactivated MMP-2 and MMP-9. Moreover, HHS increased the tightening of tight junctions (TJs), which was demonstrated by an increase in the TER, and reduced the expression the levels of claudin family members (claudin-3 and -4), which are major components involved in the tightening of TJs.Conclusions: The present findings demonstrated that HHS attenuated the migration and invasion of bladder cancer 5637 cells by modulating the activity of the PI3K/Akt signaling pathway and also through TJ tightening.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.3
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• pp.89-95
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• 2020

This study is a descriptive research to investigate the effects of nurses' internal orientation, social support and job orientation on turnover intention. The subjects were two university hospital nurses in D metropolitan city who agreed to participate in the study. Data collection was conducted from October 2, 2018 to March 20, 2019. The data were analyzed using SPSS 22.0 program, frequency and percentage, mean and standard deviation, correlation analysis, t-test, ANOVA, Pearson's correlation, and multiple regression. The study results were 3.04 ± .62 points for internal orientation policy, 3.08 ± .55 points for social support, 3.81 ± .59 points for peers, 3.67 ± .60 points for family members, and 2.98 ± 0.43 points for job placement and intention to turnover. The degree of turnover decreased with higher internal orientation, social support and job orientation. An examination of the general characteristics of the factors affecting turnover intention showed significant results with clinical experience and working department. The higher the clinical experience, the higher the turnover intention, and the department of work showed the higher turnover intention in the order of surgical ward, medical ward, ICU, and OR. These results show the need to actively develop and educate programs to improve nurses' intention to turnover, as well as internal hospital-oriented policies, social support, and job placement.

• The Journal of Korean Medicine
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• v.17 no.1 s.31
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• pp.48-83
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• 1996

Our conclusions for function evaluation tools of Stroke patients are as follows. 1. Evaluating tools of Activities of Daily Living, Katz Index, Barthel Index, Modified Barthel Index have high validity and reliability because of ease of measuring, high accuracy, consistency, sensitivity and sufficient stastistics, but they mainly measure motor function except sense, mentation, language, and social conception. Therefore cerebrovascular disease and brain injury in trauma patients with lacked acknowledgement and sensation, we are not able to apply these tools. 2. PULSES Profile is a useful scale for measuring the patient's over-all status, upper and lower limb functions, sensory components, excretary functions, and intellectual and emotional adaptabilities. It is recognized as a good, useful tool to evaluate patient's whole function. 3. Motor Assessment Scale was designed to measure the progress of stroke patients. The scale was supplemented with upper arm function items. We believe that the Motor Assessment Scale could be a useful evaluation tool with inter-rater reliability ,test-retest reliability. 4. The existing evaluation tools, Katz Index, Barthel Index, Modified Barthel Index, PULSES Profile, Motor Assessment Scale, mainly measured the rehabilitational motor function of sequela of cerebrovascular patients. On the other hand CNS & INH stroke scale can measure cerebrovascular disease patient's neurologic deficits and over-all stautus, which are recognition ability, speech status, motor function, sensory function, activities of daily living. Those scales have been recognized as useful tools to measure function of cerebrovascular disease patients and have increased in use. 5. Every function evaluation tool was recognized to have some validity and inter-rater, test-retest reliability in items of each evaluation tool and total scores of each evaluation tools, but it is thought that none of these scales have been fully validated and proved reliable. Therefore afterward, the development of a highly reliable rating system may best be accomplished by a careful comparison of several tools, using the same patients and the same observers in order to choose the most reliable items from each. 6. Ideal evaluation tools must have the following conditions; (1) It should show the objective functional statues at the same time. (2) It should be repeated consecutively to know changed function status. (3) It should be easy to observe the treatment program. (4) It should have the same result with another rater to help rater exchange information with treatment team members. (5) It should be practical and simple. (6) The patient should not suffer from the observer.

• Journal of Radiation Protection and Research
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• v.40 no.4
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• pp.211-215
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• 2015

In case of radiation emergencies, radioactive materials released into environments can cause internal exposure of members of the public. Even though whole body counters are widely used for direct measurement of internally deposited radionuclides, those are not likely to be used at the field to rapidly screen internal exposure. In this study, we estimated the counting efficiencies of portable NaI detector for different size BOMAB phantoms using Monte Carlo transport code to apply handheld gamma spectrometers for rapid screening of internal exposure following radiological accidents. As a result of comparison for two counting geometries, counting efficiencies for sitting model were about 1.1 times higher than those for standing model. We found, however, that differences of counting efficiencies according to different size are higher than those according to counting geometry. Therefore, we concluded that when we assess internal exposure of small size people compared to the reference male, the body size should be considered to estimate more accurate radioactivity in the human body because counting efficiencies of 4-year old BOMAB phantom were about 2.4~3.1 times higher than those of reference male BOMAB phantom.

• Korean Journal of Construction Engineering and Management
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• v.14 no.2
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• pp.65-77
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• 2013

Recent economic slump is making the construction industry's overall construction business environment worse. Contractors which are under the legal management and/or walk out are to the brink of 25 companies according to the Construction association of Korea released in 2011. It means that existing construction companies are required to transform the fundamental ideology of existing operation framework, and besides, existing companies should be transformed to service industry in order to proceed further into the developing future industries. In this study, it will be chosen the internal marketing related factor like 'Satisfying employees, internal customer, are the first thing to do in order to satisfy external customer.' which is about existing service industry field before its implementation in construction companies. In addition, appropriateness test will be performed including both interactions between each of the factors affect mutually and looking into any management improvement effects on contractors. And also, this proposal is suggested by approaching with internal marketing strategy which is both paradigm shift for customers by construction company members and another internal communication way as a means of overcoming the crisis of overall construction industry under currently happening.

• Proceedings of the Korea Concrete Institute Conference
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• 1998.10a
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• pp.577-581
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• 1998

Recent trends in the construction of building frame feature the increase use of composite steel concrete members functioning together in what terms of mixed structural systems. One of such systems, RCS(reinforced concrete column and steel beam) system, is known to make use of type of member in the most efficient manner to maximize the structural and economic benifits. Based on the results, joint behavior and design were described in terms of two primary modes of failure ; joint panel shear and vertical bearing. In test specimen, joint deformation is observed at internal region greater than at external region.

• Journal of Information Technology Applications and Management
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• v.11 no.4
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• pp.1-23
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• 2004

This study identifies communication patterns of groups using synchronous text communication medium for their group decision-making, and examines how these patterns are associated with creative solutions to problems. Our research suggests that certain communication behavior of groups, when appropriately organized, can be of help in enhancing creative production of outcomes. A qualitative study was conducted on communication patterns based on an analysis of text-based electronic conversation protocols. Specifically this research tried to overcome existing studies on electronic groups by focusing on interactive process of communication among participants. The major study conclusion; are: (1) The production of creative outcome may depend on the process or sequence of discussion among group members with synchronous text communication medium. That is, proper interactive responses and appropriate control of the discussion process are essential to obtain a high level of performance. (2) It is importantto make discuss rules based on meta-cognitive and interactive protocols in the early stage. Explicit rules relating to internal group processes as well as communication medium use are even more important to groups with electronic communication medium than face-to-face groups.