• Title/Summary/Keyword: Internal Cavity

검색결과 393건 처리시간 0.021초

Feasibility of normal tissue dose reduction in radiotherapy using low strength magnetic field

  • Jung, Nuri Hyun;Shin, Youngseob;Jung, In-Hye;Kwak, Jungwon
    • Radiation Oncology Journal
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    • 제33권3호
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    • pp.226-232
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    • 2015
  • Purpose: Toxicity of mucosa is one of the major concerns of radiotherapy (RT), when a target tumor is located near a mucosal lined organ. Energy of photon RT is transferred primarily by secondary electrons. If these secondary electrons could be removed in an internal cavity of mucosal lined organ, the mucosa will be spared without compromising the target tumor dose. The purpose of this study was to present a RT dose reduction in near target inner-surface (NTIS) of internal cavity, using Lorentz force of magnetic field. Materials and Methods: Tissue equivalent phantoms, composed with a cylinder shaped internal cavity, and adjacent a target tumor part, were developed. The phantoms were irradiated using 6 MV photon beam, with or without 0.3 T of perpendicular magnetic field. Two experimental models were developed: single beam model (SBM) to analyze central axis dose distributions and multiple beam model (MBM) to simulate a clinical case of prostate cancer with rectum. RT dose of NTIS of internal cavity and target tumor area (TTA) were measured. Results: With magnetic field applied, bending effect of dose distribution was visualized. The depth dose distribution of SBM showed 28.1% dose reduction of NTIS and little difference in dose of TTA with magnetic field. In MBM, cross-sectional dose of NTIS was reduced by 33.1% with magnetic field, while TTA dose were the same, irrespective of magnetic field. Conclusion: RT dose of mucosal lined organ, located near treatment target, could be modulated by perpendicular magnetic field.

실내모형시험을 통한 도로함몰 매커니즘에 대한 기초적 연구 (Basic Study on Mechanism of Cave-in in Road through Laboratory Model Tests)

  • 권기철;김상록;홍석우
    • 한국도로학회논문집
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    • 제18권5호
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    • pp.11-19
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    • 2016
  • PURPOSES : This study identifies the causes and the mechanism of the occurrence of underground cavities. METHODS : A case study on cave-in and a series of model tests with a small soil chamber were conducted. RESULTS : A hypothesis about the mechanism of the cave-in in road was established, and the basic influencing factors on underground cavity expansion were identified. CONCLUSIONS : It was found that the characteristics of shear strength of soil and direction of water flow had a larger influence on cavity formation and expansion than the characteristics of internal erosion. In addition, large cavities suddenly expanded when cavities were caused owing to breakage of buried sewer pipe.

Tuberculosis-Infected Giant Bulla Treated by Percutaneous Drainage Followed by Obliteration of the Pulmonary Cavity Using Talc: Case Report

  • Heo, Jeongwon;Bak, So Hyeon;Ryu, Se Min;Hong, Yoonki
    • Journal of Chest Surgery
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    • 제54권5호
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    • pp.408-411
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    • 2021
  • Tuberculosis (TB)-infected giant bullae are rare. A 55-year-old man was referred when an infected bulla did not respond to empirical treatment. Computed tomography showed a giant bulla in the right upper lobe with an air-fluid level and surrounding infiltrate. Sputum culture, acid-fast bacilli (AFB) stain, and polymerase chain reaction (PCR) for TB were negative. Percutaneous drainage of the bullous fluid was performed. AFB stain and PCR were positive in the drained fluid. The patient was given anti-TB drugs and later underwent obliteration of the pulmonary cavity using talc. To summarize, we report a patient with a TB-infected giant bulla that was treated successfully with anti-TB drugs and obliteration of the pulmonary cavity using talc.

종격동 내 발생한 활막 육종 1예 (A Case of Synovial Sarcoma in Mediastinum)

  • 윤용훈;강동욱;공은정;엄상용;이진서;류지원;김우성
    • Journal of Yeungnam Medical Science
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    • 제30권1호
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    • pp.51-54
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    • 2013
  • Synovial sarcoma is a rare malignancy in the thoracic cavity, especially in the mediastinum. In this paper, a case of primary mediastinal synovial sarcoma is reported. A 34-year-old woman was hospitalized with dyspnea. Her chest X-ray and computed tomography (CT) showed a $16{\times}13{\times}11$ cm mass in her anterior mediastinal space. Surgical resection was performed but was incomplete. The pathological and immunohistochemical analysis confirmed the diagnosis of monophasic spindle cell synovial sarcoma. The patient underwent adjuvant radiotherapy for two months, but local recurrence and metastasis occurred in her pleural cavity. She eventually underwent chemotherapy for one year and died 18 months after her operation.

Cavity 형상비에 따른 혼합 중대 효과의 수치적 연구 (NUMERICAL STUDY OF MIXING ENHANCEMENT EFFECT DUE TO THE CONFIGURATION RATIO OF CAVITY)

  • 오주영;배영우;김기수;변영환;이재우
    • 한국전산유체공학회:학술대회논문집
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    • 한국전산유체공학회 2005년도 추계 학술대회논문집
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    • pp.245-248
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    • 2005
  • SCRamjet is the key technology for hypersonic flight over mach number 6. It is characterized by very short residence time in combustor because its internal flow is supersonic. In this short time, the whole process of combustion must be done. Especially numerical study of combustor is important because air-fuel mixing rate influences the performance of combustor. Various methods of air-fuel mixing enhancement are proposed. Among these, cavity injection method is selected to study in this paper. The numerical study is conducted with the variation of the cavity length at the fixed height of unit and jet injection on the downstream of cavity.

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음향에너지를 이용한 내부 혼합형 이유체 분사노즐의 분무특성 (Spray Characteristics of Internal-Mixing Twin-Fluid Atomizer using Sonic Energy)

  • 조형건;강원수;석지권;이근선;이충원
    • 한국분무공학회지
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    • 제4권3호
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    • pp.32-41
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    • 1999
  • In this research, internal-mixing twin-fluid atomizer using sonic energy is designed and manufactured. We are trying to intimate high efficiency twin-fluid atomizer to obtain good liquid atomization in the low pressure region. Define of geometric form of atomizer, characteristics of spray is influenced by position, depth and height variation of cavity resonator, variation of sound intensity and resonant sound frequency with liquid flow rate. The liquid atomization is promoted by multi-stage disintegration of mixing flow of gas with liquid and the optimum condition of position and depth of cavity resonator according to sonic energy is obtained from the condition at a=2.5mm and L=2mm. The velocity distribution of droplets shows negative value due to recirculation region at the center of axial, and as the radial direction distance is far, the velocity distribution of droplets decrease slowly after having a maximum value. However velocity and SMD show nearly uniform distribution at the down stream and as result compared to Nukiyama and Tanasawa's equation. atomization of mixing flow with air and liquid dispersing from the outlet of the nozzle is promoted by the effect of collision at the cavity resonator.

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Improved Regenerative Responses of Injured Spinal Cord Nerve Fibers by the Treatment of Sukjihwang(Rehmanniae radix preparat)

  • Han, Kyu-Sul;Seol, In-Chan;Ryu, Ho-Ryong;Jo, Hyun-Kyung;An, Jung-Jo;NamGung, Uk;Kim, Yoon-Sik
    • 동의생리병리학회지
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    • 제21권6호
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    • pp.1569-1575
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    • 2007
  • In oriental medicine, Sukjihwang (SJH, Rehmanniae radix preparat) has been used as one of the key ingredients for the prescription of several herbal decoctions and applied clinically for the treatment of several diseases including nervous system and cardiovascular disease. Here, possible growth-promoting effects of SJH on injured spinal cord axons were investigated in the rats. SJH administration increased levels of active form of ERK1/2 protein and Cdc2 proteins in the injured spinal cord tissue. Anterograde DiI-tracing of corticospinal tract axons showed that SJH-treatment enhanced axonal arborization in the injury area and extensive axonal extension into the caudal area. In SJH-treated group, glial scar formed after spinal cord injury was confined in a smaller area compared to the control group, and the trabecula structure was well observed within the injury cavity. Furthermore, increased proliferation and migration of astrocytes in the injury cavity were observed by SJH treatment. Thus, these present data provide a biological evidence on potential importance of SJH therapy for the treatment of injured spinal cord.

2차원과 3차원 아음속 공동 유동 특성에 대한 수치적 연구 (NUMERICAL ANALYSIS OF TWO- AND THREE-DIMENSIONAL SUBSONIC TURBULENT CAVITY FLOWS)

  • 최홍일;김재수
    • 한국전산유체공학회:학술대회논문집
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    • 한국전산유체공학회 2007년도 추계 학술대회논문집
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    • pp.187-193
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    • 2007
  • The flight vehicles have cavities such as wheel wells and bomb bays. The flow around a cavity is characterized as unsteady flow because of the formation and dissipation of vortices due to the interaction between the freestream shear layer and cavity internal flow, the generation of shock and expansion waves. Resonance phenomena can damage the structures around the cavity and negatively affect aerodynamic performance and stability. In the present study, numerical analysis was performed for cavity flows by the unsteady compressible three dimensional Reynolds-Averaged Navier-Stokes (RANS) equations with Wilcox's ${\kappa}\;-\;{\omega}$ turbulence model. The cavity has the aspect ratios of 2.5, 3.5 and 4.5 for two-dimensional case, same aspect ratios with the W/D ratio of 2 for three-dimensional case. The Mach and Reynolds numbers are 0.53 and 1,600,000 respectively. The flow field is observed to oscillate in the "shear layer mode" with a feedback mechanism. Based on the SPL(Sound Pressure Level) analysis of the pressure variation at the cavity trailing edge, the dominant frequency was analyzed and compared with the results of Rossiter's formula. The MPI(Message Passing Interface) parallelized code was used for calculations by PC-cluster.

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LES를 이용한 열린 공동 유동과 공동 내 물질 확산의 수치적 모사 (LARGE EDDY SIMULATION OF FLOW AND MASS EXCHANGE PROCESSES BETWEEN A CHANNEL AND AN OPEN CAVITY)

  • 장경식;박승오
    • 한국전산유체공학회:학술대회논문집
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    • 한국전산유체공학회 2005년도 추계 학술대회논문집
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    • pp.239-243
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    • 2005
  • Fully three-dimensional Large Eddy Simulation calculations of the flow past 2D cavity are conducted to study the purging of neutrally buoyant or dense miscible contaminants introduced instantaneously inside the cavity. The length to depth ratio(L/D) is 2 and Reynolds number based on the depth is 3,360. Fully developed turbulent inflow are fed at the inlet from precursor simulation of channel flow. Mean flow pattern and unsteady features are investigated based on the experimental data of Pereira and Sousa. From the study of mass exchange processes, it is found that the mechanism of removal of the contaminant is very different between the non-buoyant and buoyant cases. In the buoyant case, internal wave motion which interacts with a strong cavity vortex is dominant in the ejection mechanism of the contaminants.

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Thermal-hydraulic behavior simulations of the reactor cavity cooling system (RCCS) experimental facility using Flownex

  • Marcos S. Sena;Yassin A. Hassan
    • Nuclear Engineering and Technology
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    • 제55권9호
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    • pp.3320-3325
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    • 2023
  • The scaled water-cooled Reactor Cavity Cooling System (RCCS) experimental facility reproduces a passive safety feature to be implemented in Generation IV nuclear reactors. It keeps the reactor cavity and other internal structures in operational conditions by removing heat leakage from the reactor pressure vessel. The present work uses Flownex one-dimensional thermal-fluid code to model the facility and predict the experimental thermal-hydraulic behavior. Two representative steady-state cases defined by the bulk volumetric flow rate are simulated (Re = 2,409 and Re = 11,524). Results of the cavity outlet temperature, risers' temperature profile, and volumetric flow split in the cooling panel are also compared with the experimental data and RELAP system code simulations. The comparisons are in reasonable agreement with the previous studies, demonstrating the ability of Flownex to simulate the RCCS behavior. It is found that the low Re case of 2,409, temperature and flow split are evenly distributed across the risers. On the contrary, there's an asymmetry trend in both temperature and flow split distributions for the high Re case of 11,524.