• Title/Summary/Keyword: Intermediate stress

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Inhibitory Activity of Blueberries on UVB-induced Oxidative Stress and Matrix Metalloproteinase Expression in Human Skin Fibroblasts (인간피부 섬유아세포에서 UVB 유도된 산화 스트레스와 기질금속단백질가수분해효소 발현에 블루베리의 저해능)

  • Jang, Young Ah;Kim, Se Gie
    • Journal of Life Science
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    • v.29 no.12
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    • pp.1321-1328
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    • 2019
  • Intermediate-wavelength solar radiation, also known as ultraviolet B (UVB: 290-320 nm) radiation, may cause premature aging and oxidative damage-dependent skin cancer in humans. UVB-induced formation of reactive oxygen species (ROS)-often a consequence of excessive exposure to these rays-could activate matrix metalloproteinases (MMPs) such as MMP-1 and MMP-3. These enzymes break down type I collagen in human fibroblasts. In this study, we assessed the antioxidant and anti-aging effects of ethyl acetate extract of blueberry (EEB). An antioxidant test in blueberries evaluated ROS production using CCD-986sk cells and DPPH assay. In order to evaluate the anti-wrinkle efficacy of blueberries, the MMP-1 production and type 1 procollagen synthesis evaluated and the expression of MMP 1, 3 were tested through Western blot and RT- PCR. EEB exhibited 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity and reduced the production of UVB-induced ROS. Also, EEB inhibited UVB-induced processes associated with photoaging and skin cancer, such as reduction in procollagen production and increase in MMP-1 production. More precisely, EEB (50 ㎍/ml) markedly suppressed mRNA and protein levels of MMP-1 and -3. The anti-aging effects are attributable to the antioxidant activity of EEB. These findings indicate that EEB has a protective effect against UVB-induced aging in human fibroblast cells by regulating the levels of type-1 procollagen, MMP-1, and MMP-3.

Ocean Surface Winds Over the Seas Around Korea Measured by the NSCAT(NASA Scatterometer) (NSCAT (NASA Scatterometer)에 의한 한국근해의 해상풍)

  • 이동규
    • Korean Journal of Remote Sensing
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    • v.14 no.1
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    • pp.37-52
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    • 1998
  • The NSCAT(NASA Scatterometer) carried by the japanese Advanced Earth Observing Satellite(ADEOS) was the first high resolution(25 km) device for the direct wind measurement over the ocean. Even it was ceased to operate in lune of 1977 because of the power failure, it gave the first opportunity to the marine meteorologists to study the direct measured ocean wind during its 9 months of operation, especially around Korea. This study is to show monthly mean ocean wind and wind stress curl fields around Korea from January, 1997 to June, 1997. Mean ocean winds in January are predominantly northwesterly and the strongest wind(12 m/s) is found near Vladivostok. The winds in the western East Sea are strongly inf1uenced by the mountain range in Korea and these topographically influenced winds make about five times larger wind stress curl fields than previous estimates based on the weather maps. The calculation of Sverdrup transport in the East Sea shows the possibility of the directional change of the East Korean Cold Current from southward to northward direction caused by the winter wind. The downwelling area near North Korea has maximum estimated speed of 45 m in january and this wind induced downwelling makes good condition for the formation of Intermediate East Sea Water together with vigorous mixing by the strong wind.

Paleogene dyke swarms in the eastern Geoje Island, Korea: their absolute ages and tectonic implications (거제도 동부에 분포하는 고제3기 암맥군: 절대연대와 지구조적 의미)

  • Son, Moon;Kim, Jong-Sun;Hwang, Byoung-Hoon;Lee, In-Hyun;Kim, Jeong-Min;Song, Cheol-Woo;Kim, In-Soo
    • The Journal of the Petrological Society of Korea
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    • v.16 no.2 s.48
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    • pp.82-99
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    • 2007
  • The Paleogene dikes intruding into the late Cretaceous granodiorite are pervasively observed in the Irun-myeon, eastern Geoje Island. They are classified into three groups: NW-trending acidic dike swarm and WNW- (A-Group) and $NS{\sim}NNE-trending$ (B-Group) basic dike swarms. Based on their cross-cutting relationships, the earliest is the acidic dike group and fellowed by A- and B-Groups in succession. The acidic dikes seem to have intruded into tension gashes induced by the sinistral strike-slip faulting of the Yangsan fault system during the late $Cretaceous{\sim}early$ Paleogene. In terms of rock-type, orientation, age, and geochemistry, A-Group and B-Group are intimately correlated with the intermediate and basic dike swarms in the Gyeongju-Gampo area, respectively. These results significantly suggest that the corresponding dike swarms are genetically related. Based on the K-Ar and Ar-Ar age data, A- and B- Groups were intruded during $64{\sim}52\;Ma$ and $51{\sim}44\;Ma$, respectively. The result means that the direction of tensional stress in and around the SE Korean peninsula was changed abruptly from NNE-SSW to $EW{\sim}WNW-ESE$ at about 51 Ma. Considering the tectonic environments during the Paleogene, it is interpreted that A-Group was injected along the WNW-trending tensional fractures developed under an regional sinistral simple shear regime which was caused by the north-northwestward oblique subduction of the Pacific plate beneath the Eurasian plate. Meanwhile, the regional stress caused by the collision of India and Eurasia continents at about 55 Ma was likely propagated to the East Asia at about 51 Ma, and then the East Asia including the Korean peninsula was extruded eastwards as a trench-rollback and the dip of downgoing slab of the Pacific plate was abruptly steepened. As a result, the strong suction-force along the plate boundary produced a tensional stress field trending EW or WNW-ESE in and around the Korean peninsula, which resultantly induced B-Group to intrude passively into the study area.

Comparison of Cognitive Loads between Koreans and Foreigners in the Reading Process

  • Im, Jung Nam;Min, Seung Nam;Cho, Sung Moon
    • Journal of the Ergonomics Society of Korea
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    • v.35 no.4
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    • pp.293-305
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    • 2016
  • Objective: This study aims to measure cognitive load levels by analyzing the EEG of Koreans and foreigners, when they read a Korean text with care selected by level from the grammar and vocabulary aspects, and compare the cognitive load levels through quantitative values. The study results can be utilized as basic data for more scientific approach, when Korean texts or books are developed, and an evaluation method is built, when the foreigners encounter them for learning or an assignment. Background: Based on 2014, the number of the foreign students studying in Korea was 84,801, and they increase annually. Most of them are from Asian region, and they come to Korea to enter a university or a graduate school in Korea. Because those foreign students aim to learn within Universities in Korea, they receive Korean education from their preparation for study in Korea. To enter a university in Korea, they must acquire grade 4 or higher level in the Test of Proficiency in Korean (TOPIK), or they need to complete a certain educational program at each university's affiliated language institution. In such a program, the learners of the Korean language receive Korean education based on texts, except speaking domain, and the comprehension of texts can determine their academic achievements in studying after they enter their desired schools (Jeon, 2004). However, many foreigners, who finish a language course for the short-term, and need to start university study, cannot properly catch up with university classes requiring expertise with the vocabulary and grammar levels learned during the language course. Therefore, reading education, centered on a strategy to understand university textbooks regarded as top level reading texts to the foreigners, is necessary (Kim and Shin, 2015). This study carried out an experiment from a perspective that quantitative data on the readers of the main player of reading education and teaching materials need to be secured to back up the need for reading education for university study learners, and scientifically approach educational design. Namely, this study grasped the difficulty level of reading through the measurement of cognitive loads indicated in the reading activity of each text by dividing the difficulty of a teaching material (book) into eight levels, and the main player of reading into Koreans and foreigners. Method: To identify cognitive loads indicated upon reading Korean texts with care by Koreans and foreigners, this study recruited 16 participants (eight Koreans and eight foreigners). The foreigners were limited to the language course students studying the intermediate level Korean course at university-affiliated language institutions within Seoul Metropolitan Area. To identify cognitive load, as they read a text by level selected from the Korean books (difficulty: eight levels) published by King Sejong Institute (Sejonghakdang.org), the EEG sensor was attached to the frontal love (Fz) and occipital lobe (Oz). After the experiment, this study carried out a questionnaire survey to measure subjective evaluation, and identified the comprehension and difficulty on grammar and words. To find out the effects on schema that may affect text comprehension, this study controlled the Korean texts, and measured EEG and subjective satisfaction. Results: To identify brain's cognitive load, beta band was extracted. As a result, interactions (Fz: p =0.48; Oz: p =0.00) were revealed according to Koreans and foreigners, and difficulty of the text. The cognitive loads of Koreans, the readers whose mother tongue is Korean, were lower in reading Korean texts than those of the foreigners, and the foreigners' cognitive loads became higher gradually according to the difficulty of the texts. From the text four, which is intermediate level in difficulty, remarkable differences started to appear in comparison of the Koreans and foreigners in the beginner's level text. In the subjective evaluation, interactions were revealed according to the Koreans and foreigners and text difficulty (p =0.00), and satisfaction was lower, as the difficulty of the text became higher. Conclusion: When there was background knowledge in reading, namely schema was formed, the comprehension and satisfaction of the texts were higher, although higher levels of vocabulary and grammar were included in the texts than those of the readers. In the case of a text in which the difficulty of grammar was felt high in the subjective evaluation, foreigners' cognitive loads were also high, which shows the result of the loads' going up higher in proportion to the increase of difficulty. This means that the grammar factor functions as a stress factor to the foreigners' reading comprehension. Application: This study quantitatively evaluated the cognitive loads of Koreans and foreigners through EEG, based on readers and the text difficulty, when they read Korean texts. The results of this study can be used for making Korean teaching materials or Korean education content and topic selection for foreigners. If research scope is expanded to reading process using an eye-tracker, the reading education program and evaluation method for foreigners can be developed on the basis of quantitative values.

Effect of High Temperature and High Humidity on Protein Expression and Plasma Membrane $H^{+}ATPase$ of Umbel with Flower of Onion (Allium cepa L.) (고온과 고습 조건하에서 양파 화구의 총 단백질의 발현과 원형질막 $H^{+}ATPase$의 영향)

  • Ku, Yang-Gyu;Park, Won;Lee, Eul-Tai;Kim, Cheol-Woo;Oh, Jeong-Min;Jang, Young-Seok;Kim, Yong-Kwon;Ahn, Sung-Ju
    • Journal of Bio-Environment Control
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    • v.18 no.2
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    • pp.160-165
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    • 2009
  • This study was undertaken the effect of high temperature and high humidity on protein expression and especially plasma membrane (PM) $H^{+}ATPase$ of umbel with flowers of early cultivar 'Shinsunhwang' and intermediate cultivar 'Maebsihwang' of onion (Allium cepa L.). There were no visible any difference on the protein pattern from before flowering stage to full flowering stage of two onion cultivars, however, seed set stages were revealed induced/deduced protein patterns. At day 18, protein expression pattern of the high temperature and high humidity treatments of two cultivars was significantly reduced compared to controls. Furthermore, various protein expression of the high temperature treatment was more reduced compared to high humidity treatment. PM $H^{+}ATPase$ expression of the control plants of two onion cultivars was clearly shown, but was not detectable under high temperature treatment of the two onion cultivars using western blot analysis. PM $H^{+}ATPase$ expression of the high humidity treatment was faintly detected intermediate cultivar 'Maebsihwang', not early cultivar 'Shinsunhwang'. These results indicate that protein expression pattern and PM $H^{+}ATPase$ under high temperature treatment was considered to be more damaged compared to high humidity.

The Relationship between Walking exercise and Quality of Life for Korean Adults (우리나라 성인의 걷기운동과 삶의 질의 관련성)

  • Jang, Young-Hee;Kim, So-Hui;Kim, Yu-Suk;Jung, Sun-Hee;Park, Jong
    • Journal of Digital Convergence
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    • v.11 no.5
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    • pp.325-334
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    • 2013
  • The study is to observe a degree of relation between quality of life and a degree of walking exercise for adult residents of cities of Korea. From data of the 4th round 3rd-year Korea National Health and Examination Survey, 7,851 in which 3,892 were male residents and 3,959 females, were selected as subjects, excluding 723 who didn't answer at least more than one question for 5th degree of EQ-5D and physical activities. As a result, quality of life showed statistically significant relation among gender, education level, spouses, average monthly income, stress, a number of chronic diseases, health recognition and whether walking exercise undertaken. Especially one who carried out walking exercise showed higher quality of life than one who did not. This showed more significant difference of quality of life between whether the exercise was undertaken and whether it is intensified or intermediate. Therefore, in accordance with results of this study, it is necessary to develop an effective exercise program that is designed to let residents to exercise in a regular basis and to guarantee a sustainable support from government.

Metabolic Engineering of the Brassinosteroid Biosynthetic Pathways (Brassinosteroid의 대사공학)

  • LEE Mi-Ock;SONG Ki-Hong;LEE Hyun-Kyung;JUNG Ji-Yoon;CHOE Vit-Nary;CHOE Sunghw
    • Proceedings of the Korean Society of Plant Biotechnology Conference
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    • 2002.04a
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    • pp.69-75
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    • 2002
  • Sterols play two major roles in plants: a bulk component in biological membranes and precursors of plant steroid hormones. Physiological effects of plant steroids, brassinosteroids (BRs), include cell elongation, cell division, stress tolerance, and senescence acceleration. Arabidopsis mutants that carry genetic defects in BR biosynthesis or its signaling display characteristic phenotypes, such as short robust inflorescences, dark-green round leaves, and sterility. Currently there are more than 100 dwarf mutants representing 7 genetic loci in Arabidopsis. Mutants of 6 loci, dwf1/dim1/cbb1, cpd/dwf3, dwf4, dwf5, det2/dwf6, dwf7 are rescued by exogenous application of BRs, whereas bri1/dwf2 shares phenotypes with the above 6 loci but are resistant to BRs. These suggest that the 6 loci are defective in BR biosynthesis, and the one locus is in BR signaling. Biochemical analyses, such as intermediate feeding tests, examining the levels of endogenous BR, and molecular cloning of the genes revealed that dwf7, dwf5, and dwf1 are defective in the three consecutive steps of sterol biosynthesis, from episterol to campesterol via 5-dehydroepisterol. Similarly, det2/dwf6, dwf4, and cpd/dwf3 were shown to be blocked in $D^4$ reduction, 22a-hydroxylation, and 23 a-hydroxylation, respectively. A signaling mutant bri1/dwf2 carries mutations in a Leucine-rich repeat receptor kinase. Interestingly, the bri1 mutant was shown to accumulate significant amount of BRs, suggesting that signaling and biosynthesis are dynamically coupled in Arabidopsis. Thus It is likely that transgenic plants over-expressing the rate-limiting step enzyme DWF4 as well as blocking its use by BRI1 could dramatically increase the biosynthetic yield of BRs. When applied industrially, BRs will boost new sector of plant biotechnology because of its potential use as a precursor of human steroid hormones, a novel lead compound for cholesterol-lowering effects, and a various application in plant protection.

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Tertiary Dyke Swarms and their Tectonic Importance in the Southeastern Part of the Korean Peninsula (한반도 남동부 제3기 암맥군과 지구조적 중요성)

  • Kim, Jin-Seop;Son, Moon;Kim, Jong-Sun;Kim, In-Soo
    • The Journal of the Petrological Society of Korea
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    • v.11 no.3_4
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    • pp.169-181
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    • 2002
  • Basic~intermediate dike swarms are pervasively developed in the east of the Ulsan Fault, SE Korea. Most of them intruded initially along the NS-trending extensional fractures which developed under EW extension during the East Sea opening in the Early Miocene (before about 17 Ma). The mean-strikes of the basic dikes intruding into the granites are more clockwise rotated in farther eastern side, i. e.$ N06^{\circ}$E, $Nl5^{\circ}$E, and $N37^{\circ}$E in the western side, in the just vicinities, and in the eastern side of the YBonil Tectonic Line (YTL), respectively. And the mean-strike of the basic dikes nearby shoreline is also most clockwise rotated ($N75^{\circ}$E in the Guryongpo Peninsula). The spatial variance indicates that the dikes, located only in the east of the YTL, experienced horizontal-clockwise rotation, and that the dikes in farther east from the YTL experienced more clockwise rotation. It is, thus, supported that the NNW dextral shear stress, generated by the spreading of the East Sea, was propagated toward inland from eastern continental margin of the Korean Peninsula, and that the YTL is an westernmost limit of the clockwise crustal rotations which are pervasively observed in the vicinities of the Miocene basins, SE Korea.

A Meta-analysis of variables related to organizational commitment of social workers (사회복지사의 조직몰입과 관련된 변인에 관한 메타분석)

  • Lee, Jung-Gun
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.11
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    • pp.455-464
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    • 2020
  • This study examined the correlation between the variables related to the organizational commitment of social workers. The research results are as follows. First, the overall effect size of the variable group had an intermediate effect size. Among the four organizational commitment-related variables, the job-related negative variable had the largest effect size. Next, the group of positive variables related to the organization, the group of positive variables related to the job, and the group of individuals related to the individual were in order. Second, among the individual-related variables, experience, gender, and education showed a small effect size, and other factors were close to the small effect size. In the group of positive variables related to organization, all variables except for transactional leadership and organizational fairness, which had a medium effect size, showed a large effect size. The job-related positive variables showed a large effect size only for job satisfaction, and customer orientation and job suitability were close to the large effect size. The turnover intention, which is a group of job-related negative variables, had a large effect size and job stress showed a medium effect size.

A study on the effect that brand image in sports equipment gets in consumer product purchase (스포츠용품에 있어서 브랜드 이미지가 소비자 제품구매에 미치는 영향에 관한 연구)

  • 윤선영;전성복
    • Archives of design research
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    • v.16 no.2
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    • pp.385-394
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    • 2003
  • Modem market's tendency is displaying brand strategy of Corporation sells product and consumer buys rand'.Brand acts by intermediate that reflect consumer's request and experience and attach product and consumer hat produce. Successful brand intended strategy empirical esthetics enemy, and consumer recognizes brand to novel experience and think by one fixed idea (awareness). any corporations wish to get maximum effect into minimum investment expense that reduce huge public elations and advertisement charge. Do to incuse impression for product brand through direct interview with consumer at purchase visual point, and do function hat drive purchase and the importance great rawly. Therefore, sight expression of brand image must be able to from immobile one impression in consumer's spirit being inked nearly with brand .Brand that situate by affirmative impression once can arrive in purchase by brand without alternative information being withdrawn by consumer's emory. Solution of visual expression for this being city cornification laying stress on logo and mark of brand as central element of brand image, speak as communication actor who back this. This to be Dija as direction that product and connection are deep before meaning that is sight language enemy who allow fetters special quality and the seniority in age sex language enemy of brand as ell as have direction of by methods method for problem solution present can .Therefore, relation with brand image analysis of sports equipment and consumer product purchase that this research forms market economy theoretical investigating to be effective and present direction that is image-making to be consistency this the purpose be.

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