• Asian-Australasian Journal of Animal Sciences
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• 제29권8호
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• pp.1120-1128
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• 2016

The objective of this work was to evaluate the effects of supplementation with nitrogen and starch on the nutritional performance of grazing cattle during the rainy season. Five rumen cannulated Nellore steers, averaging 211 kg of body weight (BW), were used. Animals grazed on five signal grass paddocks. Five treatments were evaluated: control (forage only), ruminal supplementation with nitrogen at 1 g of crude protein (CP)/kg BW, ruminal supplementation with starch at 2.5 g/kg BW, supplementation with nitrogen (1 g CP/kg BW) and starch (2.5 g/kg BW), and supplementation with nitrogen (1 g CP/kg BW) and a mixture of corn starch and nitrogenous compounds (2.5 g/kg BW), thereby resulting in an energy part of the supplement with 150 g CP/kg of dry matter (DM). This last treatment was considered an additional treatment. The experiment was carried out according to a $5{\times}5$ Latin square design following a $2{\times}2+1$ factorial arrangement (with or without nitrogen, with or without starch, and the additional treatment). Nitrogen supplementation did not affect (p>0.10) forage intake. Starch supplementation increased (p<0.10) total intake but did not affect (p<0.10) forage intake. There was an interaction between nitrogen and starch (p<0.10) for organic matter digestibility. Organic matter digestibility was increased only by supplying starch and nitrogen together. Nitrogen balance (NB) was increased (p<0.10) by the nitrogen supplementation as well as by starch supplementation. Despite this, even though a significant interaction was not observed (p>0.10), NB obtained with nitrogen plus starch supplementation was greater than NB obtained with either nitrogen or starch exclusive supplementation. Supplementation with starch and nitrogen to beef cattle grazing during the rainy season can possibly improve digestion and nitrogen retention in the animal.

• 대한후두음성언어의학회지
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• 제8권1호
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• pp.18-26
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• 1997

There are two types of phonetic study, acoustic and physiologic, for differentiating the three manner categories of Korean stop consonants. On the physiologic studies, there are endoscopic, electromyographic(EMG), electroglottographic(EGG) and aerodynamic studies. In this study, I tried to investigate general features of Korean stops using EGG study for the open quotient of vocal fold and baseline shift during speech, and aerodynamic characteristics for e subglottal air pressure, air flow and glottal resistance at consonants. On the aerodynamic study, the glottalized and aspirated stops may be characterized by e increasing subglottal pressure comparing with lenis stop at consonants. The airflow is largest in the aspirated stops followed by lenis stops and glottalized. The glottal airway resistance (GAR) showed highest in the glottalized followed by the lenis, but lowest in e aspirated during e production of consonants, and showed highest in e aspirated, but low in the glottalized and lenis during the production of vowel. The glottal resistance at consonant showed significant difference among consonants and significant interaction between subject and types of consonant. The glottal resistance at vowel showed significant difference among consonants, and e interaction occured between subject and types of consonant. The electroglottography(EGG) has been used for investigating e functioning of e vocal folds during its vibration. The EGG should be related to the patterns of the vocal fold vibration during phonation in characterizing the temporal patterns of each vibratory cycle. The purpose of this study is to investigate the dynamic change of EGG waveforms during continuous speech. The dynamic changes of EGG waveforms fir the three-way distinction of Korean stops were characterized that the aspirated stop appears to be characterized by largest open quotient and smallest glottal contact area of the vocal folds in e initial portion of vocal fold vibration ; the lenis stop by moderate open quotient and glottal contact area ; but the glottalized stop by smallest open quotient and largest glottal contact area. There may be close relationship between the OQ(open quotient) in the initial voice onset and the glottal width at the time of consonant production, the larger glottal width just before vocal fold vibration results in the smaller OQ of the vocal fold vibration in the initial voice onset. The EGG changes of baseline shift during continuous speech production were characterized by the different patterns for the three types of Korean consonants. The small and less stiffness change of baseline shift was found for the lenis and the glottalized, and the largest and stiffest change was found for the aspirated. On the baseline shift for the initial voice onset, they showed so similar patterns with for the consonant production, larger changed in the aspirated. for the lenis and the glottalized during the initial voice onset, three subjects showed individual difference each other. I suggest at s characteristics were strongly related with articulatory activity of vocal tract for the production of consonant, especially for the aspirated stop. The suspecting factors to affect EGG waveforms are glottal width, vertical laryngeal movement and the intrapharyngeal pressure to neighboring tissue during connected spech. So the EGG may be an useful method to describe laryngeal activity to classify pulsing conditions of the larynx during speech production, and EGG research can be controls for monitoring the vocal tract articulation, although above factors to affect EGG would have played such a potentially role on vocal fold vibratory behavior obtained using consonant production.

• 감성과학
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• 제18권4호
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• pp.59-74
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• 2015

제품이나 서비스에서 사용자가 예상하지 못한 의외성을 제공할 때 사용자는 만족을 넘어 감동할 수 있으며, 최근 몇몇 애플리케이션이나 웹서비스는 이러한 의외성을 제공하고 있다. 그러나 의외성 자체는 오히려 사용 용이성을 떨어뜨리는 등 문제를 야기 시킬 수 있음에도, 기존 모바일 애플리케이션 관련 연구들은 주로 사용성 중심의 만족을 다루었다. 따라서 본 연구에서는 이러한 의외성으로 인한 사용자 경험의 변화를 세렌디피티(뜻밖의 발견으로부터 유발되는 예상치 못한 즐거움) 개념을 이용하여 모바일 애플리케이션의 UX 분야에서 실험적으로 확인하고, 이로부터 유발되는 요인이 사용자 만족에 미치는 영향에 대해 관찰했다. 즉, 모바일 애플리케이션의 인터랙션을 통해 유발시킨 의외성과 동시에 게임 요소를 제공한 세렌디피티, 지각된 신규성과 지각된 사용 용이성, 지각된 유용성, 그리고 만족 등의 요인들 간 관계를 살펴봤다. 그 결과 세렌디피티가 지각된 신규성에 정(+)의, 사용 용이성에 부(-)의 영향을 미치고, 지각된 신규성과 지각된 사용 용이성이 지각된 유용성에 정(+)의 영향을 미치며, 세 가지 요인 모두 사용자 만족에 정(+)의 영향을 미치는 것이 관찰됐다.

• 생물정신의학
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• 제18권2호
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• pp.95-100
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• 2011

Objectives To evaluate the drug interactions between aripiprazole and haloperidol, authors investigated plasma concentrations of those drugs by genotypes. Method Fifty six patients with a confirmed Diagnostic and Statistical Manual of Mental Disorders 4th edition diagnosis of schizophrenia were enrolled in this eight-week, double blind, placebo-controlled study. Twenty-eight patients received adjunctive aripiprazole treatment and twenty-eight patients received placebo while being maintained on haloperidol treatment. Aripiprazole was dosed at 15 mg/day for the first 4 weeks, and then 30 mg for the next 4 weeks. The haloperidol dose remained fixed throughout the study. Plasma concentrations of haloperidol and aripiprazole were measured by high-performance liquid chromatography-tandem mass spectrometry (LC-MS/MS) at baseline, week 1, 2, 4 and 8. $^*1$, $^*5$, and $^*10$ B alleles of CYP2D6 and $^*1$ and $^*3$ alleles of CYP3A5 were determined. The Student's T-test, Pearson's Chi-square test, Wilcoxon Rank Sum test and Logistic Regression analysis were used for data analysis. All tests were two-tailed and significance was defined as an alpha < 0.05. Results In the frequency of CYP2D6 genotype, $^*1/^*10$ B type was most frequent (36.5%) and $^*1/^*1$ (30.8%), $^*10B/^*10B$ (17.3%) types followed. In the frequency of CYP3A5 genotype, $^*3/^*3$ type was found in 63.5% of subjects, and $^*1/^*3$ type and $^*1/^*1$ were 30.8% and 5.8% respectively. The plasma levels of haloperidol and its metabolites did not demonstrate significant time effects and time-group interactions after adjunctive treatment of aripiprazole. The genotypes of CYP2D6 and 3A5 did not affect the plasma concentration of haloperidol in this trial. No serious adverse event was found after adding aripiprazole to haloperidol. Conclusion No significant drug interaction was found between haloperidol and aripiprazole. Genotypes of CYP2D6 and 3A5 did not affect the concentration of haloperidol after adding aripiprazole.

• Asian-Australasian Journal of Animal Sciences
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• 제15권12호
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• pp.1760-1764
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• 2002

In order to elucidate the physiological function of circulating IGF-I on muscle protein synthesis in the chicken under malnutritional conditions, we administrated recombinant chicken IGF-I using a osmotic mini pump to fasted young chickens and measured the rate of muscle protein synthesis and plasma metabolite. The pumps delivered IGF-I at the rate of $22{\mu}g/d\{300{\mu}g{\cdot}(kg\;body\;weight{\cdot}d)^{-1}\}$. Fractional rate of protein synthesis in the muscle was measured using a large dose injection of L-[$2,6-^3H$]phenylalanine. Constant infusion of chicken IGF-I did not affect plasma glucose level. Significant interaction between dietary treatment and IGF-I infusion was observed in plasma NEFA and total cholesterol concentrations. When chicks were fasted, IGF-I infusion decreased plasma NEFA and total cholesterol concentrations. On the other hand, IGF-I administration did not affect plasma levels of both metabolites. Fasting reduced plasma triglyceride concentration significantly. IGF-I infusion also decreased the level of plasma triglyceride. Plasma IGF-I concentration of young chickens was halved by fasting for 1 d. IGF-I infusion using an osmotic minipump for 1 d increased plasma IGF-I concentration in fasted chicks to the level of fed chicks. Fasting decreased body weight and the loss of body weight was significantly ameliorated by IGF-I infusion. There was a significant interaction between dietary treatment and IGF-I infusion in the fractional rate of breast muscle protein synthesis. There was no effect of IGF-I infusion on muscle protein synthesis in fed chicks. Muscle protein synthesis reduced by fasting was ameliorated by IGF-I infusion, but did not reach to the level of fed control. Muscle weight of fasted chicks infused with IGF-I was similar to fasted birds without IGF-I infusion, which suggests that muscle protein degradation would be increased by IGF-I infusion as well as protein synthesis in fasted chicks.

• 생명과학회지
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• 제26권1호
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• pp.123-128
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• 2016

본 연구의 최종 목표는 한방제제인 심적환과 심혈관계 양방 치료제인 cilostazol과 병용 투여 효과에 대한 포괄적이고 통합의학 측면에서 정확한 정보를 얻는 것이다. Cilostazol은 말초 동맥질환 치료제로 개발 된 항 혈소판 및 혈관확장제이다. 사이클릭 AMP protein kinase A를 활성 시켜 세포내 사이클릭 AMP (cAMP) 증가를 통하여 내피세포의 NO생산을 활성화 시킨다. 심적환을 단 회 또는 반복 투여 후 cilostazol의 약물 동태학적 효과를 평가하기 위하여 순수한 증류수 단회 용량과 증류수에 심적환 콜로이드 현탁액을 각각 대조군과 시험군에 투여 하여 30분 후, 두 그룹에 cilostazol를 투여하였다. 혈청은 cilostazol 약물 투여 30분 전에 수집 하였으며, cilostazol 약물 처리 후 0.25, 0.5, 0.45 및 1, 2, 4, 6, 8, 24시간 후에 각각 수집 하였다. 그 다음 실험군과 및 테스트 그룹 사이에 실로 스타 졸에서 관찰 된 약동학 적 변화를 평가 하였다. 통계적으로 유의 한 차이는 심적관 단독 투여와 반복투여군 그룹의 약물 동태 학에서 관찰되지 않았다. 이러한 연구 결과는 만성 질환 환자에서 한약제인 심적환의 투여는 cilostazol의 약동학에 영향을 미치지 않았음을 보여 주었다. 본 연구에서 얻어진 결과는 만성 혈관질환 환자에서 심적환과 cilostazol의 병용 투여를 제안하며 두 약물간의 잠재적 인 약물 상호 작용에 대한 cilostazol의 생체 이용률에 영향을 미치지 않을 것이라 판단된다.

• 감성과학
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• 제15권1호
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• pp.65-72
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• 2012

최근 인터넷의 발달과 스마트폰의 보급으로 미디어와 정보 수용자는 상호작용이 가능하게 되었고, 휴대용 디바이스를 통해 실시간으로 정보를 접할 수 있게 되었다. 하지만 정보의 특성이나 정보가 전달되는 미디어의 종류에 따라 정보 수용자가 정보에 대해 가지는 신뢰도에 영향을 준다. 이러한 이유로 미디어와 정보의 신뢰도와의 관계에 대해 많은 연구가 이루어지고 있지만, 대부분의 연구는 신문, 방송, 온라인 뉴스 매체의 신뢰도를 비교하는데 그 중점을 두고 있다. 또한 인터넷을 기반으로 쌍방향성의 특징이 있는 미디어 기기간의 신뢰도 비교연구는 드문 것이 현실이다. 이에 본 연구는 화면 크기의 차이에 따른 미디어 기기별 사용성의 차이를 가정하여, 인터넷을 통해 정보를 접할 수 있는 서로 다른 세 가지 기기(PC, 태블릿 PC, 스마트폰)가 기사정보 내용을 전달할 때 신뢰도에 어떠한 영향을 미치는지 알아보고자 하였다. 본 연구의 결과는 미디어 기기의 화면 크기에 따른 기사정보 내용의 신뢰도가 보도기사, 의견기사, 피처기사 등 기사의 종류별로 다르게 나타났다. 즉 미디어 기기의 특성에 대한 정보 수용자의 감정이나 이미지, 신뢰도 등이 그 매체를 통해 전달되는 정보에도 투영되어 상호작용하는 것을 경험적으로 확인할 수 있었다. 이러한 결과를 통해 미디어 기기의 화면 크기와 같은 사용성 차이 발생 요소들이 미디어 콘텐츠 개발에 중요한 요소로서 의미가 있음을 알 수 있다.

• 한국가금학회지
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• 제30권2호
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• pp.113-118
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• 2003

In this study, broilers were raised up to 6 weeks of age in a single room to determine if different levels of dietary protein or addition of aluminum sulfate[alum, $Al_2$(SO$_4$)$_3$ㆍ14$H_2O$] to the litter affected growth performance, production of ammonia(NH$_3$) and soluble phosphorus(SP) content of the litter.The experimental treatments consisted of six treatments in a 2x3 factorial arrangements: T$_1$＝23% protein ＋ 0.2% alum to litter; T$_2$＝21% protein ＋ 0.2% alum to litter; T$_3$＝19% protein ＋ 0.2% alum to litter; T$_4$＝23% protein ＋ no alum; T$_{5}$＝21% protein ＋ no alum; T$_{6}$＝19% protein ＋ no alum. For broiler performance, there was no effect of alum addition to the litter, but the dietary protein levels significantly affected feed intake from days 22 to 42(P<0.05) and day 0 to 42(P< 0.05), weight gain during all periods(P<0.05 or 0.01), and feed:gain from day 0 to 21(P<0.05) and day 0 to 42(P<0.05). Alum addition to the litter did not affect body weight at 21 and 42 days, but dietary protein levels has a significant effect on it at both 21(P<0.0l) and 42 days(P<0.05). Alum addition only affected ammonia production at weeks 3(P

• 한국산학기술학회논문지
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• 제17권10호
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• pp.449-457
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• 2016

청소년기는 아동에서 성인으로 넘어가는 과도기의 중간 기점으로서, 자신이 앞으로 어떠한 방향으로 살아갈지에 대한 고민과 자아를 정립하는 매우 중요한 시기이다. 이처럼 중요한 청소년기에 대한민국 청소년들의 행복지수는 OECD국가 중 최하위로, 특히 학업에 상당한 영향을 받는 것으로 조사되었다. 따라서 그들의 삶에 대한 만족도가 높을 것이라고 기대하기는 어려울 것으로 판단하였으며, 이러한 결과를 토대로 청소년들의 삶의 만족을 조절하는 요인들에는 어떠한 것이 있는지 연구하고자 하였다. 연구의 자료는 한국청소년정책연구원에서 수행된 '한국 아동 청소년 패널조사' 의 2012년도 KCYPS 중1 패널 제 3차의 원시자료를 활용하였다. 본 연구에서는 청소년의 학습태도 및 삶의 만족에 영향을 미치는 요인들을 분석하기 위해 먼저 학습태도 및 삶의 만족에 영향을 미치는 요인으로서 부모, 또래, 교사와의 관계가 중요하다고 보았다. 탐색적 요인분석을 통해 설문에 사용된 변수들 간 관계를 찾아내었고, 이들 요인간의 구조적인 관계를 규명하고자 구조방정식 모형을 이용하여 분석을 실시하였다. 실증분석 결과, 청소년 시기의 부모양육방식, 또래애착, 교사관계는 학습태도 및 삶의 만족에 상당한 영향을 미치는 것으로 나타났으며, 직접 또는 간접적으로 모두 삶의 만족에 유의한 영향을 미치는 것으로 나타났다. 분석된 결과를 통해 추후 대한민국 청소년들의 건강한 삶에 대한 결론 및 제언을 시사해보고자 하였다.

• Asian-Australasian Journal of Animal Sciences
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• 제32권6호
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• pp.865-873
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• 2019

Objective: The study was designed to investigate the effects of restraint method, restraint duration, and body weight on stress-linked hormones (corticosterone, adrenaline, and noradrenaline), blood biochemical (namely glucose and lactate), and the meat quality in broiler chickens. Methods: A total of 120 male broiler chickens (Cobb 500) were assigned to a $2{\times}3{\times}2$ factorial arrangement in a completely randomized design using two restraint methods (shackle and cone), three durations of restraint (10, 30, and 60 s), and two categories of live body weight ($1.8{\pm}0.1kg$ as lightweight and $2.8{\pm}0.1kg$ as heavyweight). Results: Irrespective of the duration of restraint and body weight, the coned chickens were found to have lower plasma corticosterone (p<0.01), lactate (p<0.001), lower meat drip loss (p<0.01), cooking loss (p<0.05), and higher blood loss (p<0.05) compared with their shackled counterparts. The duration of restraint had significant effects on the meat initial pH (p<0.05), ultimate pH (p<0.05), and yellowness (p<0.01). The lightweight broilers exhibited higher (p<0.001) blood loss and lower (p<0.05) cooking loss compared to the heavyweight broilers, regardless of the restraint method used and the duration of restraint. However, the interaction between the restraint method, duration of restraint, and body weight contributed to differences in pre-slaughter stress and meat quality. Therefore, the interaction between the restraint method and the duration of restraint affected the meat shear force, lightness ($L^*$) and redness ($a^*$). Conclusion: The duration of restraint and body weight undoubtedly affect stress responses and meat quality of broiler chickens. Regardless of the duration of restraint and body weight, the cone restraint resulted in notably lower stress, lower meat water loss, and higher blood loss compared to shackling. Overall, the findings of this study showed that restraint method, duration of restraint, and body weight may affect the stress response and meat quality parameters in broilers and should be considered independently or interactively in future studies.